The document discusses advancements in computer-aided technologies, particularly in drug design and genomics, highlighting the evolution of human genome studies and the potential for creating 'designer babies' free from genetic disorders. It emphasizes the role of computational methods in understanding complex biological systems, predicting outcomes, and improving disease treatments, with aspirations for a cancer-free society. The author envisions a future where advanced technology leads to significant improvements in healthcare without traditional human and animal testing.

1. A Galaxy Of
Codes In You........

2. TO THE ASCII OF HUMANS
-KRUPALI GANDHI

4. • Open source software-
- reproducibility
- faster development
-increased quality
- long term availability
• CADD- computer aided drug design
• CAD/CAM- computer aided design and computer
aided manufacturing
• BLAST- basic local alignment search tool

6. BIOINFOR
MATICS
COMPUTATIONAL
BIOMODELLING
COMPUTATIONAL
PHARMACOLOGY
CANCER COMPUTATIONAL
BIOLOGY
COMPUTATIONAL
GENOMICS

7. proteins
The
human
genome
project
data
Pharmacological
application

8. Darwin’s theory of evolution, the genetic bases of humans(homo sapiens) found
from apes..

9. 1953- structure of DNA
discovered
1995- first bacterial
genome
2001- first human
genome drafting starts
2004- human genome
completed
2004- computer
platform used
2010- bench-top next
gen sequencers used

10. The designer babies !!!
• Babies without
Genetic disorders!!

11. To eradicate diseases from babies is one story,
But to build a baby.....???

12. •Discovery
•Predicting
•Modeling
•Stimulating potential
therapeutic effects
•Pharmacokinetics

13.  Use of computer stimulations of biological systems,
including cellular subsystems (network metabolites,
enzymes, metabolism, signal transduction pathways, gene
regulatory networks) to analyze and visualize complex
connections of these cellular processes...
 Tasks- cellular model
- multi-cellular organism stimulation
- protein folding
- brain model
- immune systems
- virtual liver
- modeling of infectious disease

14. Computer assisted surgical planning
on 3-D liver
HEPATOSYS- programme supporting
projects looking at cellular networks of the
liver cell.

15. CAD/CAM techniques
-crowns, crown lays
-Veneers,
-Inlays, onlays
-Fixed bridges,
-Dental implant restorations,
-Dentures
-Orthodontic appliances

17.  To the era of disease free kids....
 No human and animal testing of drugs
 Cancer-free society
 Looking inside humans- human genomics
drafts....
 For us- computer dentists!!!

19. Thank you