SlideShare a Scribd company logo
COMBINED ORAL
CONTRACEPTIVE PILLS
DONE BY: ALI NAJAT JABBAR
KIRKUK MEDICAL COLLAGE
INTRODUCTION
• The combined oral contraceptive pill (COCP), often
referred to as the birth control pill
• Is a type of birth control that is designed to be taken
orally by women. It includes a combination of an estrogen
(usually ethinylestradiol) and a progestogen (specifically
a progestin)
• It alters the menstrual cycle to eliminate ovulation and
prevent pregnancy.
• Have many formulations include monophasic, diphasic
and triphasic.
MECHANISM OF ACTION
• Estrogen and progesterone have negative feedback effect
which decrease the pulse frequency of gonadotropin-releasing
hormone (GnRH) release by the hypothalamus, which
decreases the secretion of follicle-stimulating hormone (FSH)
and greatly decreases the secretion of luteinizing hormone
(LH) by the anterior pituitary.
• Decreased levels of FSH inhibit follicular development,
preventing an increase in estradiol levels. Progestogen
negative feedback and the lack of estrogen positive feedback
on LH secretion prevent a mid-cycle LH surge. Inhibition of
follicular development and the absence of an LH surge prevent
ovulation.
Contraceptive use
• Combined oral contraceptive pills are a type of oral medication
that is designed to be taken every day, at the same time of day,
in order to prevent pregnancy. There are many different
formulations or brands, but the average pack is designed to be
taken over a 28-day period, or cycle. For the first 21 days of
the cycle. The last 7 days of the cycle are hormone free days
(placebo pills).
Effectiveness
the estimated risk of getting pregnant is 0.3%, or about 3 in
1000 women on COCPs will become pregnant within one year.
MEDICAL USES
Used in treatment of:
• PCOS
• Endometriosis
• Adenomyosis
• Acne
DRUG INTERACTIONS
Some drugs reduce the effect of the pill and can cause
breakthrough bleeding, or increased chance of pregnancy.
These include drugs such as rifampicin, barbiturates,
phenytoin and carbamazepine. In addition cautions are
given about broad spectrum antibiotics, such as ampicillin
and doxycycline.
SIDE EFFECTS
• Nausea, vomiting, headache, bloating, breast tenderness, swelling of
the ankles/feet (fluid retention), or weight change may occur.
• Vaginal bleeding.
• Increase the risk of venous thromboembolism (including deep vein
thrombosis (DVT) and pulmonary embolism (PE)).
• Increase the risk of ischemic stroke and myocardial infarction at
high doses.
• Increase in breast cancer risk.
• Depression (decrease of serotonin levels).
• Hypertension (increase bradykinin breakdown).
CONTRAINDICATION
• Cardiovascular disease (such as valvular heart disease or ischemic heart
disease), history of thromboembolism or pulmonary embolism,
cerebrovascular accident, migraine with aura, a familial tendency to form
blood clots (such as familial factor V Leiden), and in smokers over age 35.
• Advanced diabetes, liver tumors, hepatic adenoma or severe cirrhosis of the
liver.
• Breast cancer, endometrial cancer.
• Pregnancy.
• Women who are breastfeeding are also advised not to start COCPs until 4
weeks after birth due to increased risk of blood clots.
• Severe hypercholesterolemia and hypertriglyceridemia.
THANK YOU

More Related Content

What's hot

Drugs used or avoided in pregnancy
Drugs used or avoided in pregnancyDrugs used or avoided in pregnancy
Drugs used or avoided in pregnancy
mostafa hosni
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
vinayakgaware
 
Tocolytic drug
Tocolytic drugTocolytic drug
Tocolytic drug
magdy abdel
 
Pharmacological management of female infertility
Pharmacological management of female infertilityPharmacological management of female infertility
Pharmacological management of female infertility
Abeer Abd Elrahman
 
Oxytocics & Tocolytics
Oxytocics & TocolyticsOxytocics & Tocolytics
Oxytocics & Tocolytics
ankita0809
 
Combined oral contraceptive pills
Combined oral contraceptive pillsCombined oral contraceptive pills
Combined oral contraceptive pills
Dr.Laxmi Agrawal Shrikhande
 
Drugs used in pregnancy
Drugs used in pregnancyDrugs used in pregnancy
Drugs used in pregnancy
ethan1hunt
 
Progesterone in clinical practice
Progesterone in clinical practiceProgesterone in clinical practice
Progesterone in clinical practice
Aboubakr Elnashar
 
HORMONAL CONTRACEPTIVES
HORMONAL CONTRACEPTIVESHORMONAL CONTRACEPTIVES
HORMONAL CONTRACEPTIVES
sharonsheregar
 
Progesterone and related drugs
Progesterone and related drugsProgesterone and related drugs
Progesterone and related drugs
Azheen Kanabi
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
velspharmd
 
Estrogen and progestins
Estrogen and progestinsEstrogen and progestins
Estrogen and progestins
Pravin Prasad
 
ORAL CONTRACEPTIVES
ORAL CONTRACEPTIVES ORAL CONTRACEPTIVES
ORAL CONTRACEPTIVES
tazeensyed6
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
DRx Priya Shukla
 
Class oral contraceptives
Class oral contraceptivesClass oral contraceptives
Class oral contraceptives
Raghu Prasada
 
Uterine stimulants & relaxants
Uterine stimulants & relaxantsUterine stimulants & relaxants
Uterine stimulants & relaxants
BikashAdhikari26
 
Oral Contraceptive Pills
Oral Contraceptive Pills Oral Contraceptive Pills
Oral Contraceptive Pills
faysalahmed35
 
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
DR SHASHWAT JANI
 
Misoprostol use in Obstetrics and Gynaecology
Misoprostol use in Obstetrics and GynaecologyMisoprostol use in Obstetrics and Gynaecology
Misoprostol use in Obstetrics and Gynaecology
Chimezie Obi
 

What's hot (20)

Drugs used or avoided in pregnancy
Drugs used or avoided in pregnancyDrugs used or avoided in pregnancy
Drugs used or avoided in pregnancy
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
 
Tocolytic drug
Tocolytic drugTocolytic drug
Tocolytic drug
 
Pharmacological management of female infertility
Pharmacological management of female infertilityPharmacological management of female infertility
Pharmacological management of female infertility
 
Oxytocics & Tocolytics
Oxytocics & TocolyticsOxytocics & Tocolytics
Oxytocics & Tocolytics
 
Combined oral contraceptive pills
Combined oral contraceptive pillsCombined oral contraceptive pills
Combined oral contraceptive pills
 
Drugs used in pregnancy
Drugs used in pregnancyDrugs used in pregnancy
Drugs used in pregnancy
 
Progesterone in clinical practice
Progesterone in clinical practiceProgesterone in clinical practice
Progesterone in clinical practice
 
HORMONAL CONTRACEPTIVES
HORMONAL CONTRACEPTIVESHORMONAL CONTRACEPTIVES
HORMONAL CONTRACEPTIVES
 
Progesterone and related drugs
Progesterone and related drugsProgesterone and related drugs
Progesterone and related drugs
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
 
Estrogen and progestins
Estrogen and progestinsEstrogen and progestins
Estrogen and progestins
 
ORAL CONTRACEPTIVES
ORAL CONTRACEPTIVES ORAL CONTRACEPTIVES
ORAL CONTRACEPTIVES
 
HRT
HRTHRT
HRT
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
 
Class oral contraceptives
Class oral contraceptivesClass oral contraceptives
Class oral contraceptives
 
Uterine stimulants & relaxants
Uterine stimulants & relaxantsUterine stimulants & relaxants
Uterine stimulants & relaxants
 
Oral Contraceptive Pills
Oral Contraceptive Pills Oral Contraceptive Pills
Oral Contraceptive Pills
 
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
COMBINED ORAL CONTRACEPTIVE PILLS AND NEWER ADVANCES IN CONTRACEPTION BY DR S...
 
Misoprostol use in Obstetrics and Gynaecology
Misoprostol use in Obstetrics and GynaecologyMisoprostol use in Obstetrics and Gynaecology
Misoprostol use in Obstetrics and Gynaecology
 

Similar to Combined oral contraceptive pills

Estrogen, progesterone and contraceptives
Estrogen, progesterone and contraceptivesEstrogen, progesterone and contraceptives
Estrogen, progesterone and contraceptives
DrShrey Bhatia
 
contraception.pptx
contraception.pptxcontraception.pptx
contraception.pptx
PrilaVk
 
Oral contraceptive
Oral contraceptiveOral contraceptive
Oral contraceptive
Koppala RVS Chaitanya
 
PH1.40.pptx
PH1.40.pptxPH1.40.pptx
PH1.40.pptx
Dr-Mani Bharti
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
Rajesh Yadav
 
L4-Pharmacology of local anesthesia.esters and amides
L4-Pharmacology of local anesthesia.esters and amidesL4-Pharmacology of local anesthesia.esters and amides
L4-Pharmacology of local anesthesia.esters and amides
bwalyakangwa582
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
ankit
 
Gonadal Hormones And Inhibitors.pptx
Gonadal Hormones And Inhibitors.pptxGonadal Hormones And Inhibitors.pptx
Gonadal Hormones And Inhibitors.pptx
Dr. Maria Qammar
 
Contraception & famiy planning
Contraception & famiy planningContraception & famiy planning
Contraception & famiy planning
Naila Memon
 
9 Pregnancy and Lactation.pptx
9 Pregnancy and Lactation.pptx9 Pregnancy and Lactation.pptx
9 Pregnancy and Lactation.pptx
Sani42793
 
COCP.pptx
COCP.pptxCOCP.pptx
Induction of lactation in fostering mothers
Induction of   lactation   in   fostering   mothersInduction of   lactation   in   fostering   mothers
Induction of lactation in fostering mothers
muhammad al hennawy
 
Oral contraceptives by shivam
Oral contraceptives by shivamOral contraceptives by shivam
Oral contraceptives by shivam
Shivam Diwaker
 
progesterone receptor.pptx
progesterone receptor.pptxprogesterone receptor.pptx
progesterone receptor.pptx
ashharnomani
 
Drm science lecture 2 CONTRACEPTIVES AND IUDs
Drm science lecture 2 CONTRACEPTIVES AND IUDsDrm science lecture 2 CONTRACEPTIVES AND IUDs
Drm science lecture 2 CONTRACEPTIVES AND IUDs
Raghu Prasada
 
ORAL CONTRACEPTIVE PILL.pptx
ORAL CONTRACEPTIVE PILL.pptxORAL CONTRACEPTIVE PILL.pptx
ORAL CONTRACEPTIVE PILL.pptx
markcofie2
 
Hormonal contraception
Hormonal contraceptionHormonal contraception
Hormonal contraception
Dr. Pramod B
 
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptxSEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
Bakut John Maiganga
 
Oral Contraceptive Pills (OCP)
Oral Contraceptive Pills (OCP)Oral Contraceptive Pills (OCP)
Oral Contraceptive Pills (OCP)
Roshan Subedi
 
Progesterone & oral contraceptives
Progesterone & oral contraceptivesProgesterone & oral contraceptives
Progesterone & oral contraceptives
Chintan Doshi
 

Similar to Combined oral contraceptive pills (20)

Estrogen, progesterone and contraceptives
Estrogen, progesterone and contraceptivesEstrogen, progesterone and contraceptives
Estrogen, progesterone and contraceptives
 
contraception.pptx
contraception.pptxcontraception.pptx
contraception.pptx
 
Oral contraceptive
Oral contraceptiveOral contraceptive
Oral contraceptive
 
PH1.40.pptx
PH1.40.pptxPH1.40.pptx
PH1.40.pptx
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
 
L4-Pharmacology of local anesthesia.esters and amides
L4-Pharmacology of local anesthesia.esters and amidesL4-Pharmacology of local anesthesia.esters and amides
L4-Pharmacology of local anesthesia.esters and amides
 
Oral contraceptives
Oral contraceptivesOral contraceptives
Oral contraceptives
 
Gonadal Hormones And Inhibitors.pptx
Gonadal Hormones And Inhibitors.pptxGonadal Hormones And Inhibitors.pptx
Gonadal Hormones And Inhibitors.pptx
 
Contraception & famiy planning
Contraception & famiy planningContraception & famiy planning
Contraception & famiy planning
 
9 Pregnancy and Lactation.pptx
9 Pregnancy and Lactation.pptx9 Pregnancy and Lactation.pptx
9 Pregnancy and Lactation.pptx
 
COCP.pptx
COCP.pptxCOCP.pptx
COCP.pptx
 
Induction of lactation in fostering mothers
Induction of   lactation   in   fostering   mothersInduction of   lactation   in   fostering   mothers
Induction of lactation in fostering mothers
 
Oral contraceptives by shivam
Oral contraceptives by shivamOral contraceptives by shivam
Oral contraceptives by shivam
 
progesterone receptor.pptx
progesterone receptor.pptxprogesterone receptor.pptx
progesterone receptor.pptx
 
Drm science lecture 2 CONTRACEPTIVES AND IUDs
Drm science lecture 2 CONTRACEPTIVES AND IUDsDrm science lecture 2 CONTRACEPTIVES AND IUDs
Drm science lecture 2 CONTRACEPTIVES AND IUDs
 
ORAL CONTRACEPTIVE PILL.pptx
ORAL CONTRACEPTIVE PILL.pptxORAL CONTRACEPTIVE PILL.pptx
ORAL CONTRACEPTIVE PILL.pptx
 
Hormonal contraception
Hormonal contraceptionHormonal contraception
Hormonal contraception
 
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptxSEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
SEX HORMONES (Oestrogen Progesterone and their Antagonist.pptx
 
Oral Contraceptive Pills (OCP)
Oral Contraceptive Pills (OCP)Oral Contraceptive Pills (OCP)
Oral Contraceptive Pills (OCP)
 
Progesterone & oral contraceptives
Progesterone & oral contraceptivesProgesterone & oral contraceptives
Progesterone & oral contraceptives
 

More from Ali Najat

HYDROCARBONS (KEROSENE) POISENING
HYDROCARBONS (KEROSENE) POISENINGHYDROCARBONS (KEROSENE) POISENING
HYDROCARBONS (KEROSENE) POISENING
Ali Najat
 
Cardiomyopathies.pdf
Cardiomyopathies.pdfCardiomyopathies.pdf
Cardiomyopathies.pdf
Ali Najat
 
NORMAL LABOUR.pdf
NORMAL LABOUR.pdfNORMAL LABOUR.pdf
NORMAL LABOUR.pdf
Ali Najat
 
Acute exacerbation of asthma
Acute exacerbation of asthmaAcute exacerbation of asthma
Acute exacerbation of asthma
Ali Najat
 
Upper GIT Bleeding
Upper GIT BleedingUpper GIT Bleeding
Upper GIT Bleeding
Ali Najat
 
Anthrax
AnthraxAnthrax
Anthrax
Ali Najat
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
Ali Najat
 
Brucellosis
BrucellosisBrucellosis
Brucellosis
Ali Najat
 
Sjogren's syndrome
Sjogren's syndromeSjogren's syndrome
Sjogren's syndrome
Ali Najat
 
Budd chiari syndrome
Budd chiari syndromeBudd chiari syndrome
Budd chiari syndrome
Ali Najat
 
Zollinger ellison syndrome
Zollinger ellison syndromeZollinger ellison syndrome
Zollinger ellison syndrome
Ali Najat
 
BCG vaccine
BCG vaccineBCG vaccine
BCG vaccine
Ali Najat
 

More from Ali Najat (12)

HYDROCARBONS (KEROSENE) POISENING
HYDROCARBONS (KEROSENE) POISENINGHYDROCARBONS (KEROSENE) POISENING
HYDROCARBONS (KEROSENE) POISENING
 
Cardiomyopathies.pdf
Cardiomyopathies.pdfCardiomyopathies.pdf
Cardiomyopathies.pdf
 
NORMAL LABOUR.pdf
NORMAL LABOUR.pdfNORMAL LABOUR.pdf
NORMAL LABOUR.pdf
 
Acute exacerbation of asthma
Acute exacerbation of asthmaAcute exacerbation of asthma
Acute exacerbation of asthma
 
Upper GIT Bleeding
Upper GIT BleedingUpper GIT Bleeding
Upper GIT Bleeding
 
Anthrax
AnthraxAnthrax
Anthrax
 
Typhoid fever
Typhoid feverTyphoid fever
Typhoid fever
 
Brucellosis
BrucellosisBrucellosis
Brucellosis
 
Sjogren's syndrome
Sjogren's syndromeSjogren's syndrome
Sjogren's syndrome
 
Budd chiari syndrome
Budd chiari syndromeBudd chiari syndrome
Budd chiari syndrome
 
Zollinger ellison syndrome
Zollinger ellison syndromeZollinger ellison syndrome
Zollinger ellison syndrome
 
BCG vaccine
BCG vaccineBCG vaccine
BCG vaccine
 

Recently uploaded

Fish and Chips - have they had their chips
Fish and Chips - have they had their chipsFish and Chips - have they had their chips
Fish and Chips - have they had their chips
GeoBlogs
 
Unit 8 - Information and Communication Technology (Paper I).pdf
Unit 8 - Information and Communication Technology (Paper I).pdfUnit 8 - Information and Communication Technology (Paper I).pdf
Unit 8 - Information and Communication Technology (Paper I).pdf
Thiyagu K
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
MIRIAMSALINAS13
 
Digital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and ResearchDigital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and Research
Vikramjit Singh
 
Thesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.pptThesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.ppt
EverAndrsGuerraGuerr
 
The French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free downloadThe French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free download
Vivekanand Anglo Vedic Academy
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
Celine George
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
DeeptiGupta154
 
Language Across the Curriculm LAC B.Ed.
Language Across the  Curriculm LAC B.Ed.Language Across the  Curriculm LAC B.Ed.
Language Across the Curriculm LAC B.Ed.
Atul Kumar Singh
 
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCECLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
BhavyaRajput3
 
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
EugeneSaldivar
 
The Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official PublicationThe Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official Publication
Delapenabediema
 
Operation Blue Star - Saka Neela Tara
Operation Blue Star   -  Saka Neela TaraOperation Blue Star   -  Saka Neela Tara
Operation Blue Star - Saka Neela Tara
Balvir Singh
 
2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...
Sandy Millin
 
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxStudents, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
EduSkills OECD
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
beazzy04
 
MARUTI SUZUKI- A Successful Joint Venture in India.pptx
MARUTI SUZUKI- A Successful Joint Venture in India.pptxMARUTI SUZUKI- A Successful Joint Venture in India.pptx
MARUTI SUZUKI- A Successful Joint Venture in India.pptx
bennyroshan06
 
Sectors of the Indian Economy - Class 10 Study Notes pdf
Sectors of the Indian Economy - Class 10 Study Notes pdfSectors of the Indian Economy - Class 10 Study Notes pdf
Sectors of the Indian Economy - Class 10 Study Notes pdf
Vivekanand Anglo Vedic Academy
 
Ethnobotany and Ethnopharmacology ......
Ethnobotany and Ethnopharmacology ......Ethnobotany and Ethnopharmacology ......
Ethnobotany and Ethnopharmacology ......
Ashokrao Mane college of Pharmacy Peth-Vadgaon
 
Chapter 3 - Islamic Banking Products and Services.pptx
Chapter 3 - Islamic Banking Products and Services.pptxChapter 3 - Islamic Banking Products and Services.pptx
Chapter 3 - Islamic Banking Products and Services.pptx
Mohd Adib Abd Muin, Senior Lecturer at Universiti Utara Malaysia
 

Recently uploaded (20)

Fish and Chips - have they had their chips
Fish and Chips - have they had their chipsFish and Chips - have they had their chips
Fish and Chips - have they had their chips
 
Unit 8 - Information and Communication Technology (Paper I).pdf
Unit 8 - Information and Communication Technology (Paper I).pdfUnit 8 - Information and Communication Technology (Paper I).pdf
Unit 8 - Information and Communication Technology (Paper I).pdf
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
 
Digital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and ResearchDigital Tools and AI for Teaching Learning and Research
Digital Tools and AI for Teaching Learning and Research
 
Thesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.pptThesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.ppt
 
The French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free downloadThe French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free download
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
 
Language Across the Curriculm LAC B.Ed.
Language Across the  Curriculm LAC B.Ed.Language Across the  Curriculm LAC B.Ed.
Language Across the Curriculm LAC B.Ed.
 
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCECLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
CLASS 11 CBSE B.St Project AIDS TO TRADE - INSURANCE
 
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
 
The Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official PublicationThe Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official Publication
 
Operation Blue Star - Saka Neela Tara
Operation Blue Star   -  Saka Neela TaraOperation Blue Star   -  Saka Neela Tara
Operation Blue Star - Saka Neela Tara
 
2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...2024.06.01 Introducing a competency framework for languag learning materials ...
2024.06.01 Introducing a competency framework for languag learning materials ...
 
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxStudents, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptx
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
 
MARUTI SUZUKI- A Successful Joint Venture in India.pptx
MARUTI SUZUKI- A Successful Joint Venture in India.pptxMARUTI SUZUKI- A Successful Joint Venture in India.pptx
MARUTI SUZUKI- A Successful Joint Venture in India.pptx
 
Sectors of the Indian Economy - Class 10 Study Notes pdf
Sectors of the Indian Economy - Class 10 Study Notes pdfSectors of the Indian Economy - Class 10 Study Notes pdf
Sectors of the Indian Economy - Class 10 Study Notes pdf
 
Ethnobotany and Ethnopharmacology ......
Ethnobotany and Ethnopharmacology ......Ethnobotany and Ethnopharmacology ......
Ethnobotany and Ethnopharmacology ......
 
Chapter 3 - Islamic Banking Products and Services.pptx
Chapter 3 - Islamic Banking Products and Services.pptxChapter 3 - Islamic Banking Products and Services.pptx
Chapter 3 - Islamic Banking Products and Services.pptx
 

Combined oral contraceptive pills

  • 1. COMBINED ORAL CONTRACEPTIVE PILLS DONE BY: ALI NAJAT JABBAR KIRKUK MEDICAL COLLAGE
  • 2. INTRODUCTION • The combined oral contraceptive pill (COCP), often referred to as the birth control pill • Is a type of birth control that is designed to be taken orally by women. It includes a combination of an estrogen (usually ethinylestradiol) and a progestogen (specifically a progestin) • It alters the menstrual cycle to eliminate ovulation and prevent pregnancy. • Have many formulations include monophasic, diphasic and triphasic.
  • 3. MECHANISM OF ACTION • Estrogen and progesterone have negative feedback effect which decrease the pulse frequency of gonadotropin-releasing hormone (GnRH) release by the hypothalamus, which decreases the secretion of follicle-stimulating hormone (FSH) and greatly decreases the secretion of luteinizing hormone (LH) by the anterior pituitary. • Decreased levels of FSH inhibit follicular development, preventing an increase in estradiol levels. Progestogen negative feedback and the lack of estrogen positive feedback on LH secretion prevent a mid-cycle LH surge. Inhibition of follicular development and the absence of an LH surge prevent ovulation.
  • 4. Contraceptive use • Combined oral contraceptive pills are a type of oral medication that is designed to be taken every day, at the same time of day, in order to prevent pregnancy. There are many different formulations or brands, but the average pack is designed to be taken over a 28-day period, or cycle. For the first 21 days of the cycle. The last 7 days of the cycle are hormone free days (placebo pills). Effectiveness the estimated risk of getting pregnant is 0.3%, or about 3 in 1000 women on COCPs will become pregnant within one year.
  • 5. MEDICAL USES Used in treatment of: • PCOS • Endometriosis • Adenomyosis • Acne
  • 6. DRUG INTERACTIONS Some drugs reduce the effect of the pill and can cause breakthrough bleeding, or increased chance of pregnancy. These include drugs such as rifampicin, barbiturates, phenytoin and carbamazepine. In addition cautions are given about broad spectrum antibiotics, such as ampicillin and doxycycline.
  • 7. SIDE EFFECTS • Nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles/feet (fluid retention), or weight change may occur. • Vaginal bleeding. • Increase the risk of venous thromboembolism (including deep vein thrombosis (DVT) and pulmonary embolism (PE)). • Increase the risk of ischemic stroke and myocardial infarction at high doses. • Increase in breast cancer risk. • Depression (decrease of serotonin levels). • Hypertension (increase bradykinin breakdown).
  • 8. CONTRAINDICATION • Cardiovascular disease (such as valvular heart disease or ischemic heart disease), history of thromboembolism or pulmonary embolism, cerebrovascular accident, migraine with aura, a familial tendency to form blood clots (such as familial factor V Leiden), and in smokers over age 35. • Advanced diabetes, liver tumors, hepatic adenoma or severe cirrhosis of the liver. • Breast cancer, endometrial cancer. • Pregnancy. • Women who are breastfeeding are also advised not to start COCPs until 4 weeks after birth due to increased risk of blood clots. • Severe hypercholesterolemia and hypertriglyceridemia.