The document provides an overview of colonial America from 1492 to 1763. It describes the events in Europe from 1450-1600 that impacted exploration, including the development of nation-states, the Renaissance, the Age of Exploration, the Reformation, and the Scientific Revolution. It then discusses the four colonial subcultures that developed - New England, Mid-Atlantic, Chesapeake, and Southern. Key people and events are highlighted for each region, including religious, ethnic, and cultural adaptations to the local geography. Population growth and the rise of urban centers are also summarized.