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Clostridia and n-butanol - Multi-market platforms
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- 2. Clostridia and n-butanol- Multi-market platforms for profitable introduction of commodity scale renewable chemicals
- 3. Mission and History Elcritonis inventing and commercializing technologies to supplant fossil fuel consumption, reduce green house gas emissions, and accelerate the expansion of cleantech industries. History: •Evolved out of the academic laboratory of Professor Terry Papoutsakis University of Delaware in 2009 - Bryan Tracy named CEO is PI on research grants that seeded company •2011 – license technology to the world’s largest biobutanol producer •2012 – Will sign a strategic partnership for development and integration of hydrolysis technology and potentially for novel separation technology
- 4. Mission and History All non-dilutive funding and profitable by the end of 2011. History: •Evolved out of the academic laboratory of Professor Terry Papoutsakis University of Delaware in 2009 - Bryan Tracy named CEO is PI on research grants that seeded company •2011 – license technology to the world’s largest biobutanol producer •2012 – Will sign a strategic partnership for development and integration of hydrolysis technology and potentially for novel separation technology
- 5. Two platforms, numerous markets HO • Specialty chemical • Biofuel (i.e., gasoline n-butanol alternative and Jet A or JP-8) • Chemical production • Waste stream remediation & upgrading • Exotic applications - CDEPT Clostridia genetic engineering & bioprocessing
- 6. Specialty chemical market >$5 (USD) billion/year n-butanol market Chemical feedstock •Glycol ethers (17%) •Butyl acetate (21%) •Butyl acrylate (39%) Uses Product formulations •Paints/Primers •Cosmetics •Lubricating oils •Etc.
- 7. Market need forsustainable solutions Need Driver • Cost increased propylene costs* • Secured supply chains unstable propylene supply • Increasing demand (11.9% CAGR) emerging markets • Green solutions Preferred buyer opportunities • New & MUCH BIGGER market opportunities gasoline alternatives & jet fuel
- 8. Case for abiofuel - >$100B market Compared to ethanol: 2. High energy content Butanol 3. Higher air to fuel ratio Better MPG 4. Lower heat of vaporization 5. Less hygroscopic 6. Less corrosive to gasoline FLEXFUEL infrastructure 7. Blending synergies with ethanol
- 9. Elcriton niche inthe butanol value chain Feedstock Manufacture Distribution or Off-take Mechanical Hydrolysis Separation/ prep. Purification Pretreat- Fermentation ethanol/ ment acetone butanol heat/ energy HO enzyme clostridia gas Pretreatment & Conversion the Separations Hydrolysis Elcriton way
- 10. Sugar to n-butanoltechnology 5-carbons (xylose) 6-carbons (glucose) + starch hemicellulose Metabolic Engineering Considerations: Molecular-scale solutions to •What’s it eating? multi-million dollar •How fast should they grow? •Can I reduce byproduct production? bioprocessing impediments •Can I integrate with purification? •Can they tolerate hydrolysis byproducts? •Can I shift production to another feedstock?
- 11. Clostridia bioprocessing platform Straindevelopment in clostridia and related species • Genetic engineering technologies • Opportunities for related, desirable species Synthetic biology • Novel pathways for new chemicals • Opportunities in chemolithotrophic clostridia Bioprocess development & integration • Concurrent strain and bioreactor development • Bioreactor and purification integration
- 12. Advantages of themulti-market, platform approach • Flexibility in business model development • Early revenue generation (e.g., licensing) • Demonstration of commercial credibility = de-risking larger market opportunities • Opportunities for Non-recurring revenues (NRR) • Bootstrapping opportunities • Reduce dilution in early rounds of fund raising • Increase value proposition • Expand options of later stage financing (e.g., debt financing)
- 13. Clostridia bioprocessing platform Green– Black processing • Remediation and upgrading of industrial waste • Glycerol, flue gases, methane and ag wastes Gaseous fermentations • Chemolithotropic fermentations • Ideally CO2 to specialty chemicals – H2? Renewable H2 production • Photosynthetic & CO2 sequestration • Algal photobioreactor & dewatering systems – DOE and ARPA-E
- 14. For questions pleasecontact: Bryan P. Tracy, PhD 15 Reads Way Suite 106 New Castle, DE 19720 BryanTracy@elcriton.com 302-220-4760 864-921-5146
Editor's Notes
- #4 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #5 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #6 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #7 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #8 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #12 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #13 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
- #14 Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -