Step-by-Step Stereotactic Radiotherapy Planning of Vestibular Schwannoma: A G...Kanhu Charan
Step-by-Step Stereotactic Radiotherapy Planning of Vestibular
Schwannoma: A Guide to Radiation Oncologists—the ROSE
Case (Radiation Oncology from Simulation to Execution)
Assessment of Intrafraction Motion during real-time tracking in the treatment...Subrata Roy
In our experience, intrafraction motion for intracranial targets treated with fiducial free, frameless cranial SRS / SRT on CyberKnife with 6-D skull tracking, is within the acceptable range, and can be reliably detected and corrected. A PTV margin of 1 mm appears adequate to account for most of the intrafraction motion in this situation. However, significant intrafraction motion occurs during treatment delivery when mask based immobilization is used, and hence the same should be accounted for, in situations where intrafraction imaging is not being practiced. Owing to the highest level of precision, excellent automation, ease of treatment planning and delivery and avoidance of anaesthesia, CyberKnife Stereotactic Radiosurgery / Radiotherapy is highly recommended as an alternative to complex cranial neurosurgical procedures.
Step-by-Step Stereotactic Radiotherapy Planning of Vestibular Schwannoma: A G...Kanhu Charan
Step-by-Step Stereotactic Radiotherapy Planning of Vestibular
Schwannoma: A Guide to Radiation Oncologists—the ROSE
Case (Radiation Oncology from Simulation to Execution)
Assessment of Intrafraction Motion during real-time tracking in the treatment...Subrata Roy
In our experience, intrafraction motion for intracranial targets treated with fiducial free, frameless cranial SRS / SRT on CyberKnife with 6-D skull tracking, is within the acceptable range, and can be reliably detected and corrected. A PTV margin of 1 mm appears adequate to account for most of the intrafraction motion in this situation. However, significant intrafraction motion occurs during treatment delivery when mask based immobilization is used, and hence the same should be accounted for, in situations where intrafraction imaging is not being practiced. Owing to the highest level of precision, excellent automation, ease of treatment planning and delivery and avoidance of anaesthesia, CyberKnife Stereotactic Radiosurgery / Radiotherapy is highly recommended as an alternative to complex cranial neurosurgical procedures.
Eclipse Con US 2013 - Buildroot Eclipse Bundle : A powerful IDE for Embedded ...melbats
Buildroot is a tool designed by embedded Linux developers to build embedded Linux systems using cross-compilation. It allows to build a cross-compilation toolchain (or re-use an existing one), a root filesystem image with applications and libraries, a kernel image and a bootloader image or any combination of these. Buildroot is typically used to create the embedded Linux systems of industrial systems based on the ARM, PowerPC or x86 architectures, by integrating multiple existing open-source components (kernel, base components, graphical libraries, networking applications, etc.) and in-house components specific to the embedded system.
Many of the early embedded Linux developers are used to work with text editors such as Emacs or Vi. However, in the recent years, the major expansion of the embedded Linux platform has attracted many more developers that are more familiar with feature-full, integrated, and user-friendly development environments. To fulfill this need, Eclipse provides an excellent platform, especially with extensions such as CDT, the Autotools plugin, the multiple plugins from the Linux tools project, the Target Communication Framework, and more.
As many embedded Linux developers use Buildroot to build their system, it sounded natural to provide an easy-to-use integration with Eclipse. To achieve that, we:
Developed an Eclipse plugin that automatically registers the available Buildroot toolchains into Eclipse CDT. This allows application developers to transparently build their application, and then execute it and debug it on the embedded target platform directly within Eclipse.
Improved the pkg-config plugin for a better integration with different toolchains.
Created a specialized Eclipse version bundling all the useful existing plug-ins for embedded Linux developers: Eclipse CDT, our specialized Buildroot plugin, the latest remote debugging mechanisms, the Autotools plugin, Linux Tools plugins, etc.
At Eclipse Con Europe, we presented a first initial version of those developments, with basic support for compilation, remote execution and debugging. Through this new talk, we would like to present the improvements that have been brought to the project: integration with pkg-config, improvements of the remote debugging mechanisms, integration with the Autotools plugin and the LTT-ng plugins. We will demonstrate how Eclipse has been extended to match the needs of embedded Linux developers, and we will perform a live demonstration of these capabilities using an ARM development platform for which Eclipse will help build, execute and debug applications.
¿Tienes problemas de pareja? ¿Tienes problemas de relaciones? ¿Estás en una crisis de pareja? Quizá esta presentación te pueda ayudar a pasar de la luna de hiel de nuevo a la luna de miel...
Feminist Criticism: is a literary form of criticism that gives the perspective of writing through a feminist perspective. It is a political form of literature that analyzes the questions of how male and females relate to each other and the world, the repression of women and how women are portrayed in literature
The customer is always right; yet, many companies do not realize that their employees are their first customers. Successful businesses build their brand love from the inside out by focusing on their best advocates - highly engaged employees. Yet a recent Gallup Poll found 75% of the workforce are not engaged with their jobs. Companies must adapt by shifting their corporate culture as a socially conscious, community-minded generation grows within the workforce. This session will explore the power of a brand's social impact on employee engagement and organizational performance and how building internal community can be transformed into external advocacy.
I shared this talk at Columbia University's 2017 BRITE Conference on Brands, Innovation, and Technology: http://briteconference.com/agenda/
Γ6.1 Εισαγωγή στις Βάσεις Δεδομένων
Να ορίζουμε τι είναι μια βάση δεδομένων
Να διακρίνουμε τα είδη των βάσεων δεδομένων (έντυπη/ηλεκτρονική)
Να διακρίνουμε και να αναφέρουμε τα πλεονεκτήματα και τα μειονεκτήματα μιας βάσης δεδομένων
Να αναφέρουμε βάσεις δεδομένων από την καθημερινή ζωή
Να αναφέρουμε παραδείγματα προγραμμάτων διαχείρισης μηχανογραφημένων βάσεων δεδομένων.
Majorana Representation in Quantum Optics - SU(2) Interferometry and Uncertai...Saroosh Shabbir
The algebra of SU(2) is ubiquitous in physics, applicable both to the atomic spin states and the polarisation states of light. The method developed by Majorana to represent pure, symmetric spin-states of arbitrary value as a product of spin-1/2 states is a powerful tool allowing the representation of a qudit on the same geometry as a qubit, i.e., the Bloch sphere.
An experimental implementation of the Majorana representation in the realm of quantum optics is presented. The technique allows the projection of arbitrary, two-mode, pure states from a coherent state input and the construction of arbitrary interference patterns.
The representation also proves useful in delineating uncertainty limits of states with a particular spin value. Issues with traditional uncertainty relations involving the SU(2) operators, such as trivial bounds for certain states and non-invariance, are thereby resolved with the presented pictorial solution.
Presentation in the Franhoufer IIS about my thesis: A wavelet transform based...Pedro Cerón Colás
Presentation in the Franhoufer IIS about my thesis: A wavelet transform based application for seismic waves. Analysis of the performance. Code made in Matlab.
2019-06-07 Characterization and research of semiconductors with an FTIR spect...LeonidBovkun
2019-06-07 Educational seminar at EP-3 University of Wuerzburg
I will present particular experiments and related results with FTIR spectrometer, so one may consider these experiments complimentary for you research.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
2. Interferometric signatures of quantum and classical states
Do interferometric signals of quantum states differ fundam-
entally from classical states, in terms of shape and visibility?
How do the interferometric signals vary as states are trans-
formed from quantum to classical?
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 1 / 38
4. Classical Interference - First order
Unfiltered 605 nm, FWHM 5 nm HeNe laser
Chris�an Huygens
(1629-1659)
Thomas Young
(1773-1829)
All single mode states display first order interference.
First order interference does not discriminate between states.
It thus does not separate classical from quantum.
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 3 / 38
6. Quantum Interference - Hong-Ou-Mandel effect
2,0 1,1 0,2
25% 50% 25%
Classically we would get:
2,0 1,1 0,2
50% 0% 50%
When wave packets overlap:
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 5 / 38
7. Quantum Interference - Hong-Ou-Mandel effect
2,0 1,1 0,2
25% 50% 25%
Classically we would get:
2,0 1,1 0,2
50% 0% 50%
When wave packets overlap:
Hong et al., PRL (1987)
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 6 / 38
8. Higher order (multiphoton) quantum interference
Y.-S Kim et al., Opt. Express 19, 24956 (2011)
Both the genera�on and the det-
ec�on of mul�-photon states is
complicated.
Non-linear op�cs is required to
generate states.
Polarisa�on op�cs and coincide-
nce detec�on is required to
detect states.
The measurement is probabilis�c.
Only when N photodetectors click
in coincidence the result is rec-
orded.
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 7 / 38
9. N00N states, de Broglie waves and quantum phase
super-resolution
1 2 3 4 5 6
0.2
0.4
0.6
0.8
1.0
phase shi�
No. of counts
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 8 / 38
10. N00N states, de Broglie waves and quantum phase
super-resolution
phase shi�
No. of counts
0 1 2 3 4 5 6
0.0
0.2
0.4
0.6
0.8
1.0
Phase difference
Countrate
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 9 / 38
11. N00N states, de Broglie waves and quantum phase
super-resolution
2 oscillations where we
would classically expect 1!
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 10 / 38
12. N00N states, de Broglie waves and quantum phase
super-resolution
N oscillations where we
would classically expect 1!
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 11 / 38
13. N00N states, de Broglie waves and quantum phase
super-resolution
N oscillations where we
would classically expect 1!
Phase super-resolu�on : Resolve features
�mes smaller than with ordinary light
Beyond Rayleigh diffraction limit
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 12 / 38
14. N00N states, de Broglie waves and quantum phase
super-resolution
N oscillations where we
would classically expect 1!
Phase super-sensi�vity : Uncertainty
in phase measurement
Phase super-resolu�on : Resolve features
�mes smaller than with ordinary light
Beyond Rayleigh diffraction limit
Heisenberg limit
J. Jacobson, G. Björk, I. Chuang, and Y. Yamamoto, PRL 74, 4835-4838 (1995)Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 13 / 38
15. Measurement post-selection of N00N states
given that we have only available.
Suppose we want to project out the state
Write the wanted state as
Form the polynomial and factorise over complex numbers
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 14 / 38
16. Measurement post-selection of N00N states
given that we have only available.
Suppose we want to project out the state
Write the wanted state as
Form the polynomial and factorise over complex numbers
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 15 / 38
17. Measurement post-selection of N00N states
given that we have only available.
Suppose we want to project out the state
Write the wanted state as
Form the polynomial and factorise over complex numbers
D A R L
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 16 / 38
18. Measurement post-selection of N00N states
given that we have only available.
Suppose we want to project out the state
Write the wanted state as
Form the polynomial and factorise over complex numbers
D A R L
A beam spli�er has the transforma�on law
and addi�onal phase-shi� gives the transforma�on
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 17 / 38
19. Measurement post-selection of N00N states
D A R L
A beam spli�er has the transforma�on law
and addi�onal phase-shi� gives the transforma�on
Coincident detection in all 4 SPDs
projects outs the NOON4 state
from the input!
R
L
A
D
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 18 / 38
20. Post-selection using coherent state input
A linearly polarised coherent state
also has a non-zero overlap with
NOON4 state!
R
L
A
D
With very weak excita�on, probability of having 5 or more photons << probability
of having exactly 4 photons
If 4 detectors click in coincidence, we are pre�y sure we've detected NOON4 state!
K. J. Resch et al., Phys. Rev. Le�. 98, 223601 (2007)
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 19 / 38
21. Quantum optics from semi-classical states
A linearly polarised coherent state
also has a non-zero overlap with
NOON4 state!
R
L
A
D
With very weak excita�on, probability of having 5 or more photons << probability
of having exactly 4 photons
If 4 detectors click in coincidence, we are pre�y sure we've detected NOON4 state!
K. J. Resch et al., Phys. Rev. Le�. 98, 223601 (2007)
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 20 / 38
22. Generalising the projection measurement method
Any complex polynomial can be factored over the field of complex numbers.
Mathematical Theorem:
Implication:
The corresponding projector to any N-photon, two-mode state can be implemented
through a series of beam-spli�ers, polarising op�cs, and signle photon coincidence
measurements!
Example:
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 21 / 38
23. Coherent state - temporal instead of spatial splitting
Uncorrelated (product state)!
R. J. Glauber, Phys. Rev. 131, 2766 (1963)
where
Laser
Laser
Laser
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 22 / 38
24. Coherent state - temporal instead of spatial splitting
Uncorrelated (product state)!
R. J. Glauber, Phys. Rev. 131, 2766 (1963)
where
Laser
Laser
Laser
Switch spa�al spli�ng for temporal spli�ng!
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 23 / 38
25. Coherent state - temporal instead of spatial splitting
R
L
A
D
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 24 / 38
27. Arbitrary interference a using coherent state
S. Shabbir, M. Swillo, G. Björk, Phys. Rev. A 87, 053821
Birefringence
N-photon
coincident
detec�on
General two-mode state:
Overlap with phase-shifted coherent state:
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 26 / 38
28. Arbitrary interference a using coherent state
S. Shabbir, M. Swillo, G. Björk, Phys. Rev. A 87, 053821
Fourier series
Birefringence
N-photon
coincident
detec�on
General two-mode state:
Overlap with phase-shifted coherent state:
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 27 / 38
29. Arbitrary interference a using coherent state
S. Shabbir, M. Swillo, G. Björk, Phys. Rev. A 87, 053821
Fourier series
Birefringence
N-photon
coincident
detec�on
General two-mode state:
Overlap with phase-shifted coherent state:
Engineer any interference pa�ern!
Saroosh Shabbir, Gunnar Bj¨ork Interferometric signatures June 3, 2014 28 / 38