This document discusses cirrhosis of the liver, including causes, histological types, clinical features, complications, investigations, management, and prognosis. Cirrhosis results in prolonged morbidity and premature death. Common causes include alcohol, viral hepatitis, and genetic conditions. Complications include portal hypertension, ascites, hepatic encephalopathy, and hepatocellular carcinoma. Management involves treating the underlying cause, managing complications, and liver transplantation in severe cases. Prognosis depends on liver function, with 50% surviving 5 years if function is good.