Chronic periodontitis is an infectious disease that results in inflammation of the tissues supporting the teeth and progressive bone and attachment loss. It is caused mainly by plaque and can be localized, affecting less than 30% of sites, or generalized, affecting more than 30% of sites. Risk factors include diabetes, smoking, poor oral hygiene, and a genetic predisposition. Symptoms include bleeding gums, loose teeth, and pain. Diagnosis is based on clinical signs of inflammation, pocket formation, attachment and bone loss seen during examination and on radiographs.