Chicken pox is caused by the varicella-zoster virus and causes a rash that may include fever and malaise. It is highly infectious and spreads through respiratory droplets. The rash starts on the trunk and spreads outward, going through stages of macules, papules, vesicles and scabs. Complications can include pneumonia, encephalitis and Reye's syndrome in rare cases. There is no specific treatment, but isolation and disinfection can help control spread. Vaccination is effective for prevention.