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Chapter 2 Blood Circulation And
Transport
Human Blood

Made by:
 Puteri Nurliyana
 Nur Ezlyin
 Aizatul
Introduction
A normal adult human has about 5 litres of blood
Blood is a fluid tissue that is made up of liquid
and solid component
The liquid component of blood is called plasma
and the solid component comprises blood cells
such as red blood cells, white blood cells and
platelets
Both components of blood can be separated
using a centrifuge
When blood is rotated in a spinning centrifuge, it
is separated into blood cells and plasma fluid
Centrifuge
Blood Components and Their Functions

Human blood is a suspension of red blood cells,white blood
cells,platelets and plasma
Blood Components and Their Functions
Plasma
- A pale yellowish fluid
- Consists of water (90%) and 10% dissolved substances,such as
nutrient,blood protein,minerals salts and hormones
Function: To carry dissolved substances and heat around the body

Red blood cells (erythrocytes)
- Have no nucleus
- Are biconcave disc-shaped
- Contains red pigments called the haemoglobin
Function: Carry oxygen in the form of oxyhaemoglobin
Blood Components and Their Functions
White Blood Cells (leucocytes)
- Have a nucleus
-Are irregular in shape
-Colourless
-Usually larger than the red blood cells
-The number white blood cells is less than the number of red blood cells in our
body
Function: Protct the body against diseases by fighting infection

Platelets
- Have no nucleus
- Tiny pieces of cells produced in the bone marrow
- Much smaller than the red or white blood cells
Function: Help in blood clotting to prevent blood loss
Blood Group
• Human blood can be
classified into four
different groups. The
four groups are
A,B,AB and O
• The blood group is
determined by the
type of protein on the
surface of the red
blood cells
Blood Group Donor To Recipient
• Transfusion is the process of transferring blood from a
donor to a recipient
• Donating and receiving of blood must be carried out
correctly accordind to the suitability and compatibility of
blood group
• When the blood of two incompatible groups are mixed
together, the red blood cells of the donor and recipient
will clump together. This condition is called agglutination
• Agglutination reduces the efficiency of red blood cells in
transporting oxygen. It also lead to death of the recipient.
Blood Donor To Recipient
•

Compatibility of blood among
the donors and the recipients
using ABO identification
system

•

Blood group O known as the
universal donor because it can
be accepted by a person of
any blood group. It can receive
blood from the donor who has
blood group O only

•

Blood group AB known as the
universal recipient because the
person can receive blood from
the donor of any blood. It can
donate to only group AB
recipient
The Importance Of Donating Blood
•

•
•
•

•

Blood is needed for major
surgery, childbirth, or cancer
treatment
Donating blood saves lives
and bring no harm to the donor
A person can donate blood
about 4-6 times a year
A suitable donor must
generally healthy, weighs 50kg
and should be above the age
of 18
A donor may give up to 0.5
litres of blood at one time.
Handling And Storage
• The blood is collected in a sterilised bag containing
sodium citrate which prevents clotting of the blood.
• The sterilised bag of blood then stored in a refrigerator at
5 º C for 10 days or longer if glucose is added
• A sample of the blood is removed from the bag of donated 
blood. The sample is then tested for its group, the presence of 
viruses such as the AIDS virus and other unwanted substances 
will be rejected.
• Before blood is transfused, it is carefully tested against the 
recipient's blood to make sure it is a good match. Then the 
blood is transfused into the recipient through a vein in the 
recipient's arm at the correct rate and temperature
Chapter 2 blood circulation and transport

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Chapter 2 blood circulation and transport

  • 1. Chapter 2 Blood Circulation And Transport Human Blood Made by:  Puteri Nurliyana  Nur Ezlyin  Aizatul
  • 2. Introduction A normal adult human has about 5 litres of blood Blood is a fluid tissue that is made up of liquid and solid component The liquid component of blood is called plasma and the solid component comprises blood cells such as red blood cells, white blood cells and platelets Both components of blood can be separated using a centrifuge When blood is rotated in a spinning centrifuge, it is separated into blood cells and plasma fluid
  • 4. Blood Components and Their Functions Human blood is a suspension of red blood cells,white blood cells,platelets and plasma
  • 5. Blood Components and Their Functions Plasma - A pale yellowish fluid - Consists of water (90%) and 10% dissolved substances,such as nutrient,blood protein,minerals salts and hormones Function: To carry dissolved substances and heat around the body Red blood cells (erythrocytes) - Have no nucleus - Are biconcave disc-shaped - Contains red pigments called the haemoglobin Function: Carry oxygen in the form of oxyhaemoglobin
  • 6. Blood Components and Their Functions White Blood Cells (leucocytes) - Have a nucleus -Are irregular in shape -Colourless -Usually larger than the red blood cells -The number white blood cells is less than the number of red blood cells in our body Function: Protct the body against diseases by fighting infection Platelets - Have no nucleus - Tiny pieces of cells produced in the bone marrow - Much smaller than the red or white blood cells Function: Help in blood clotting to prevent blood loss
  • 7. Blood Group • Human blood can be classified into four different groups. The four groups are A,B,AB and O • The blood group is determined by the type of protein on the surface of the red blood cells
  • 8. Blood Group Donor To Recipient • Transfusion is the process of transferring blood from a donor to a recipient • Donating and receiving of blood must be carried out correctly accordind to the suitability and compatibility of blood group • When the blood of two incompatible groups are mixed together, the red blood cells of the donor and recipient will clump together. This condition is called agglutination • Agglutination reduces the efficiency of red blood cells in transporting oxygen. It also lead to death of the recipient.
  • 9. Blood Donor To Recipient • Compatibility of blood among the donors and the recipients using ABO identification system • Blood group O known as the universal donor because it can be accepted by a person of any blood group. It can receive blood from the donor who has blood group O only • Blood group AB known as the universal recipient because the person can receive blood from the donor of any blood. It can donate to only group AB recipient
  • 10. The Importance Of Donating Blood • • • • • Blood is needed for major surgery, childbirth, or cancer treatment Donating blood saves lives and bring no harm to the donor A person can donate blood about 4-6 times a year A suitable donor must generally healthy, weighs 50kg and should be above the age of 18 A donor may give up to 0.5 litres of blood at one time.
  • 11. Handling And Storage • The blood is collected in a sterilised bag containing sodium citrate which prevents clotting of the blood. • The sterilised bag of blood then stored in a refrigerator at 5 º C for 10 days or longer if glucose is added • A sample of the blood is removed from the bag of donated  blood. The sample is then tested for its group, the presence of  viruses such as the AIDS virus and other unwanted substances  will be rejected. • Before blood is transfused, it is carefully tested against the  recipient's blood to make sure it is a good match. Then the  blood is transfused into the recipient through a vein in the  recipient's arm at the correct rate and temperature