Cerebral palsy is an abnormality of motor function that is acquired before or during early childhood and affects movement, posture, and balance. It can be caused by events during pregnancy like premature birth, genetic disorders, infections, strokes or lack of oxygen to the brain. The main types of cerebral palsy are spastic, which affects muscle tone, ataxic which affects coordination, and athetoid with involuntary movements. Treatment involves physical, occupational and speech therapy as well as medications to address symptoms, with the goal of helping those with cerebral palsy to lead full lives.
Ataxic cerebral palsy is a rare form of cerebral palsy affecting around 5% to 10% of all people diagnosed. It gets its name from the word ataxia, which means lack of coordination and without order.
The term ‘cerebral palsy’ includes a group of disorders that result from permanent non-progressive brain damage during early development and are characterized by abnormalities of movement and posture.
A group of motor impairment syndromes resulting from disorders of early brain development and often associated with epilepsy and abnormalities of speech, vision and intellect
Habilitation Perspective in the management of Cerebral Palsy.pptxICDDelhi
Institute for Child Development (ICD) is a private company registered under section 25 of company registration act, 1956. ICD is the brain child of Dr. Mansoor Alam, a pediatric developmental specialist who has treated more than 50,000 children with special needs during the last 25 years. ICD is a premier organization which provides the best treatment to children with complex health issues, developmental delay, neurodevelopmental disorders and childhood onset disabilities. ICD’s facility is available to children from birth to 21 years of age. Adult with disabilities are specially supported in case of need. ICD is the only organization in India which practices integrated approach of treatment, named as Multimodal treatment / Combination Therapy for children with developmental disorders. Combination Therapy combines the best available treatments into one treatment plan to get the best result. Researches have proved that combination therapy is better than isolated therapy. In fact, pediatric developmental disorders cannot be treated in isolation. It requires a team of professionals with varied specialization.
Presently ICD has its model centre named as “PediaMed” in Malviya Nagar (South Delhi), New Delhi. The model centre has capacity to treat 100 children in daily basis.
ICD is going to have its branches in the following places
North Delhi
West Delhi
East Delhi
Noida ( UP)
Ghaziabad (UP)
Faridabad (Haryana)
Gurugram /Gurgaon (Haryana)
Bahadurgarh (Haryana)
ICD is open to collaborate with other organizations with similar interests in rest of India
Ataxic cerebral palsy is a rare form of cerebral palsy affecting around 5% to 10% of all people diagnosed. It gets its name from the word ataxia, which means lack of coordination and without order.
The term ‘cerebral palsy’ includes a group of disorders that result from permanent non-progressive brain damage during early development and are characterized by abnormalities of movement and posture.
A group of motor impairment syndromes resulting from disorders of early brain development and often associated with epilepsy and abnormalities of speech, vision and intellect
Habilitation Perspective in the management of Cerebral Palsy.pptxICDDelhi
Institute for Child Development (ICD) is a private company registered under section 25 of company registration act, 1956. ICD is the brain child of Dr. Mansoor Alam, a pediatric developmental specialist who has treated more than 50,000 children with special needs during the last 25 years. ICD is a premier organization which provides the best treatment to children with complex health issues, developmental delay, neurodevelopmental disorders and childhood onset disabilities. ICD’s facility is available to children from birth to 21 years of age. Adult with disabilities are specially supported in case of need. ICD is the only organization in India which practices integrated approach of treatment, named as Multimodal treatment / Combination Therapy for children with developmental disorders. Combination Therapy combines the best available treatments into one treatment plan to get the best result. Researches have proved that combination therapy is better than isolated therapy. In fact, pediatric developmental disorders cannot be treated in isolation. It requires a team of professionals with varied specialization.
Presently ICD has its model centre named as “PediaMed” in Malviya Nagar (South Delhi), New Delhi. The model centre has capacity to treat 100 children in daily basis.
ICD is going to have its branches in the following places
North Delhi
West Delhi
East Delhi
Noida ( UP)
Ghaziabad (UP)
Faridabad (Haryana)
Gurugram /Gurgaon (Haryana)
Bahadurgarh (Haryana)
ICD is open to collaborate with other organizations with similar interests in rest of India
Cerebral palsy is a disorder of movement, muscle tone or posture that is caused by damage that occurs to the immature, developing brain, most often before birth.
•Catchall term for a variety of disorders that affect a child’s ability to
•Move and
•Maintain posture and balance
•It only affects the brain’s ability to control the muscles and not muscles or nerves themselves
•The symptoms and which areas are affected will depend on the severity and location of the brain injury
•May include Intellectual Disbaility, seizures, language disorders, learning disabilities, vision and hearing problems.
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•Affects the development of the child so also known as a developmental disability
•Usually a life long disability but mild form may recover soon.
•The problem affects the child’s future ability to learn and do
•The effect depends on a number of factors like
Cerebral palsy, or CP, is a group of disorders that affect balance, movement, and muscle tone. “Cerebral” means the disorder is related to the brain, and “palsy” refers to weakness or a muscle problem.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
2. What is Cerebral Palsy Cerebral palsy (CP) is an abnormality of motor function (as opposed to mental function) and postural tone that is acquired at an early age, even before birth. Signs and symptoms of cerebral palsy usually show in the first year of life.
3. What Causes Cerebral Palsy Events that happen during pregnancy can cause Cerebral Palsy. The premature brain is at a high risk of bleeding, and when severe enough, it can result in cerebral palsy. Children that are born prematurely can also develop serious respiratory distress due to immature and poorly developed lungs. This can lead to periods of decreased oxygen delivered to the brain that might result in cerebral palsy White matter abnormalities are observed in many cases of cerebral palsy. Genetic disorders Stroke Blood Clots Infections of the brain Rare cause is lack of oxygen to the brain at delivery (seizures, irritability, jitteriness, feeding and respiratory problems, lethargy, and coma depending on severity.
4. Signs and symptoms Issues with the following… Muscle tone Movement, coordination, and control Reflexes Posture Balance Fine motor function Gross motor function Oromotor dysfunction- difficulty using the lips, tongue, and jaw Developmental delay Developmental milestones lacking
6. Spastic Cerebral Palsy Spastic cerebral palsy, the most common form of the disease, occurs when the brain damage occurs in the outer layer of the brain, the cerebral cortex. It is estimated that this form of CP affects between 70 to 80 percent of patients. Spastic CP affects patients in different ways, depending on the areas of the body it affects. It can affect one side of the body or just the legs.
9. Ataxia Cerebral Palsy Low muscle tone and poor coordination of movements is described as ataxic cerebral palsy. Children with ataxic cerebral palsy look very unsteady and shaky. This rare form of cerebral palsy affects the sense of balance and depth perception. Affected persons often have poor coordination and walk unsteadily with a wide based gait, placing their feet unusually far apart. They have a lot of shakiness, like a tremor you might have seen in a very old person, especially when they are trying to handle or hold a small object such as a pen. Because of the shaky movements and problems coordinating their muscles, children with ataxic cerebral palsy may take longer than other children to complete certain tasks such as writing a sentence. This form affects about 5-10 percent of the children diagnosed with cerebral palsy.
10. Athetoid cerebral palsy About 10 percent of children with cerebral palsy have athetoid cerebral palsy. Athetoid cerebral palsy is caused by damage to the cerebellum or basal ganglia. These areas of the brain are responsible for processing the signals that enable smooth, coordinated movements as well as maintaining body posture. Damage to these areas may cause a child to develop involuntary, purposeless movements, especially in the face, arms, and trunk. These involuntary movements often interfere with speaking, feeding, reaching, grasping, and other skills requiring coordinated movements. For example, involuntary grimacing and tongue thrusting may lead to swallowing problems, drooling and slurred speech. The movements often increase during periods of emotional stress and disappear during sleep. In addition, children with athetoid cerebral palsy often have low muscle tone and have problems maintaining posture for sitting and walking.
11. Mixed cerebral palsy About ten percent of children with cerebral palsy have what is known a mixed-type cerebral palsy. These children have both the tight muscle tone of spastic cerebral palsy and the involuntary movements of athetoid cerebral palsy. This is because they have injuries to both the pyramidal and extra pyramidal areas of the brain. Usually the spasticity is more obvious at first, with involuntary movements increasing when the child is between nine months and three years old. The most common mixed form includes spasticity and athetoid movements, but other combinations are also possible.
12. Treatment The physical therapist evaluates muscle tone, strength and gait (walking). The occupational therapist reviews the child's ability to perform tasks of self-help and care -- from feeding to manual dexterity. The speech therapist evaluates the child's ability to speak and understand speech. Medications for spasticity, seizures, surgery for spasticity, seizures, and vision issues are also treatment options. Children will need specialized medical care by a doctor to work with their diagnosis. Because physicians have offered limited hope in curing cerebral palsy, many families have turned to alternative methods in the treatment of their children. Such therapies may include diets, herbal remedies, aromas, play with animals, and hyperbaric oxygen.
13. Secondary impairments Some of them such as poor speech, swallowing disorders, drooling, and poor fine or gross motor coordination are the result of the motor disorder affecting specific muscles involved in those functions. Other conditions are the results of simultaneous injuries in areas of the brain besides the motor areas. Cognitive disabilities, sometimes referred to as developmental delay, is often associated with cerebral palsy. Up to 50% of patients with cerebral palsy have cognitive disabilities. However, many of these children can be educated and lead productive lives and are usually only mildly or not at all intellectually impaired. Small head size Seizures Vision issues It is difficult for children with cerebral palsy to gain weight and frequently have delayed growth. Can cause gastro esophageal reflux or obesity. Urinary tract infections Osteoporosis Fractures Constipation
14. Prognosis for recovery Since cerebral palsy is actually a set of symptoms associated with a variety of causes, potential treatments will have to be diverse. Many scientists are now focusing on recent discoveries that suggest we will be able to replace lost or damaged brain cells. We must recognize that many, and possibly most, children with cerebral palsy can lead full, meaningful, and happy lives. The team of parents, caregivers, and health practitioners have the responsibility to help the child with cerebral palsy achieve this goal. We must be sure not to leave children with CP behind and understand that they have unique qualities to share.