A 42-year old female patient presented with gastroenteritis and acute renal failure. She reported loose stools and vomiting for several days. Laboratory tests found elevated urea and creatinine levels indicating acute renal failure. She was diagnosed with acute gastroenteritis caused by Entamoeba histolytica and treated with intravenous antibiotics, antiemetics, and proton pump inhibitors. Her condition improved over the next few days with reduced vomiting and stool frequency.