The carotid sinus is a dilation at the bifurcation of the common carotid artery where it splits into the internal and external carotid arteries. It contains baroreceptors that regulate blood pressure. The carotid bodies are located behind the carotid sinus and contain chemoreceptors that respond to changes in blood oxygen, carbon dioxide, and pH levels. Carotid sinus massage is used clinically to diagnose arrhythmias by stimulating the vagus nerve, which can slow heart rate due to the carotid sinus's role in blood pressure regulation.