Myocardial diseases can be caused by drugs like anti-cancer medications, infections from viruses or bacteria, and autoimmune disorders such as systemic lupus erythematosus. There are several types of myocarditis defined by their morphology and inflammatory infiltrates, including lymphocytic, hypersensitivity, and giant cell myocarditis which are characterized by lymphocytes, macrophages, eosinophils or giant cells respectively. Myxomas are soft, gelatinous polypoid tumors of the heart that contain an abundant myxoid matrix, low cellularity and numerous small blood vessels.

1. MYOCARDIAL DISEASES

7. Other causes
• Drugs like anti cancer drugs, penicillin,
sulphonamides etc
• Autoimmune diseases like SLE, Rheumatoid
arthritis etc

9. morphology

10. • Lymphocytic myocarditis
• Active myocarditis is characterized by an interstitial
inflammatory infiltrate predominantly lymphocytic
associated with degenerating or apoptotic myocytes.
• Hypersensitivity myocarditis
• Hypersensitivity myocarditis is characterized by
perivascular infiltrates composed of lymphocytes,
macrophages, and a high proportion of eosinophils
• Giant cell myocarditis

39. Morphology
• Gross – polypoid,
pedunculated, spherical
• 1-10 cms
• Soft gelatinous with h’age
• Microscopy
• abundant myxoid matrix
• Low cellularity with stellate cells
• Numerous capillary sized vessels

51. THANK YOU