The Caribbean Islands biodiversity hotspot contains a high percentage of endemic plant and animal species despite consisting of a relatively small total land area. It faces severe threats from invasive species, land conversion, overexploitation, and other human activities. Over 25% of the region's endemic species are threatened or have already gone extinct, including many iconic species like the Cuban crocodile, Jamaican iguana, and leatherback sea turtle. The hotspot spans ocean and land areas across the Caribbean and supports exceptionally rich terrestrial and marine ecosystems that are globally important but highly endangered.