Trauma accounts for a significant percentage of hospital admissions, and is a leading cause of death among young Americans. Anaesthesiologists play a key role in the care of trauma patients, from initial resuscitation to surgical intervention. A multi-step approach is used, beginning with the primary survey to address life threats and stabilize the patient, followed by a full secondary survey and indicated investigations, and concluding with a tertiary survey before discharge to identify any missed injuries. Special considerations are required for head injuries, spinal trauma, chest trauma, and other conditions.
A basic overview on the management of intra-operative bronchospasm: the risk factors, triggers, diagnosis, prevention and management. Includes a case scenario – discussion.
A basic overview on the management of intra-operative bronchospasm: the risk factors, triggers, diagnosis, prevention and management. Includes a case scenario – discussion.
Movie quotes 1 - Improve your English vocabulary - Have fun!Paulo Bergamasco
Activity using movie quotes.
Aim: improve vocabulary in an amusing way.
practice of phrasal verbs, word formation, expressions, depended prepositions etc..
This is a presentation which contains basics of polytrauma management,ATLS, triage, critical decision making skills, application of Glasgow coma scale and complications of different management strategies, if not applied properly.
POLYTRAUMA AND DAMAGE CONTROL ORTHOPAEDICSDr Slayer
polytrauma is Injury to 2 or more organ systems leading potentially to a life threatening condition
Damage control orthopaedics is an approach to contain and stabilize an orthopaedic injury to improve patient’s physiology which are designed to avoid worsening pt’s condition due to “second hit” phenomenon
Road Traffic and Safety: Pre-Hospital CareAmit Agrawal
Trauma is the leading cause of death of young people (15-29 years)
Costs countries between 1–3% of their gross national product
Considerable economic losses to victims, their families, and to nations as a whole
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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ASA GUIDELINE
NYSORA Guideline
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
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Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Anaesthetic Care of the Unconscious, Multiple Trauma and Burns Patient
1. Care of the Unconscious;
Multiple Trauma / Burns Patient
Lasonya A. Fletcher
Medical Student, Class of 2015
Anaesthesiology, August 2013
2013 Prepared by Lasonya A. Fletcher
1
2. Introduction
• Trauma accounts for 10%-15% of all patients hospitalized.
• Trauma is the leading cause of death in Americans from the first to
the thirty-fifth year of age.
• Fifty percent of trauma deaths occur immediately, with another
30% occurring within a few hours of injury (the "golden hour").
• Anaesthesiologists directly affect the survival of trauma victims –
most victims require immediate surgery
• Role of anaesthesiologist: Often that of primary resuscitator, with
provision of anesthesia a secondary activity.
2013 Prepared by Lasonya A. Fletcher
2
3. Case
Car 1: Two Adults, Male
teenager, female child
Car 2: Two Adults, Male
child
Van: One Adult
Expected injuries?
Appropriate Management?
2013 Prepared by Lasonya A. Fletcher
3
4. Initial Evaluation
1º Survey
• [2-5 mins.]
• Airway
• Breathing
• Circulation
• Disability
• Exposure
2º Survey
• Head-to-toe Examination
• Relevant Investigations
• Definitive Repair of Injuries
3º Survey
• Repeat Head-to-toe Exam
• Repair remaining/arising injuries
Resuscitation and Assessment
Control of Haemorrhage and
Definitive repair of Injury
2013 Prepared by Lasonya A. Fletcher 4
6. Primary
Survey
Airway and
Cervical Spine
Establishing and maintaining airway = first priority
If patient can talk airway usually clear
If patient is unconscious likely require airway and
ventilator assistance
Signs of obstruction: stertor (snoring), stridor,
gurgling, paradoxical chest movements
If there is apnoea, persistent obstruction, severe head
injury, maxillofacial trauma, penetrating neck injuries
with an expanding hematoma or major chest injuries
Advanced airway management is indicated
(endotracheal intubation, cricothyrotomy or
tracheostomy)
1ºA
2013 Prepared by Lasonya A. Fletcher 6
7. Primary
Survey
Airway
and Cervical Spine
Cervical spine injury unlikely in alert patients without
neck injury or tenderness
Five criteria increase the risk of cervical spine
instability:
1. Neck pain
2. Severe distracting pain
3. Any neurological signs and symptoms
4. Intoxication
5. Loss of consciousness at the scene
A cervical spine fracture must be assumed if any
one of these criteria is present, even if there is no
known injury above the level of the clavicle.
1ºA
2013 Prepared by Lasonya A. Fletcher 7
8. Primary
Survey
Airway
and Cervical Spine
Unconscious patients with major trauma are at risk for
aspiration therefore airway should be secured quickly
with an endotracheal tube or tracheostomy.
Neck hyperextension and axial traction should be
avoided Use MILS (Manual In-line Stabilization)
Nasal intubation should be avoided in patients with
mid-face or basilar skull fractures.
1ºA
2013 Prepared by Lasonya A. Fletcher 8
12. Primary
Survey
Breathing
Feel
1ºB Subcutaneous emphysema
Tracheal shift
Broken ribs
The clinician should have a high index of
suspicion for tension pneumothorax and
haemothorax particularly in patients
with respiratory distress.
2013 Prepared by Lasonya A. Fletcher 12
13. Primary
Survey
Circulation
Adequacy of circulation is based on pulse rate, pulse
fullness, blood pressure, and signs of peripheral
perfusion.
Signs of inadequate circulation include tachycardia, weak
or unpalpable peripheral pulses, hypotension, and pale,
cool, or cyanotic extremities.
First Priority in maintaining adequate circulation: STOP
BLEEDING
Second priority: Replace intravascular volume
Cardiac arrest during transport or shortly after arrival at
hospital following penetrating chest injury is an indication
for emergency room thoracotomy
Pregnant patients at term who are in cardiac arrest or shock
often cannot be resuscitated properly until after the delivery
of the baby.
1ºC
2013 Prepared by Lasonya A. Fletcher 13
14. Primary
Survey
Circulation
Haemorrhage
Obvious sites identify and control with direct
pressure
Extremity bleeding pressure dressings and packs
Bleeding due to chest trauma (possibly intercostal
arteries) may slow down or stop when the lung has re-
expanded after the insertion of a chest tube.
Bleeding due intra-abdominal injuries may tamponade
itself, depending on the severity
Pneumatic antishock garments may work to stop bleeding in the
abdomen and lower extremities but are contraindicated in cases of
bleeding above the garment
Tourniquets can cause reperfusion injuries
1ºC
2013 Prepared by Lasonya A. Fletcher 14
15. Primary
Survey
Circulation
The trauma patient may be in shock – most
commonly hypovolemic shock
Physiological responses: tachycardia, poor
capillary perfusion, and a decrease in pulse
pressure, hypotension, tachypnea, and
delirium.
The mainstay of therapy of hemorrhagic shock
is intravenous fluid resuscitation and
transfusion
Multiple short (1.5–2 in), large-bore (14–16 gauge
or 7–8.5F) catheters are placed in easily accessible
veins.
Central lines may be useful but are time-consuming
and introduce possible life-threatening
complications
1ºC
2013 Prepared by Lasonya A. Fletcher 15
16. Primary
Survey
Circulation
FluidTherapy
Choice of fluid initially is usually based on
availability
Fully cross-matched blood ideal time-
consuming to obtain
Type-specific blood is appropriate but may
cause minor antibody reactions
Uncrossed O-neg packed RBC’s should be
reserved for life-threatening losses that cannot
be replaced by other fluids
1ºC
2013 Prepared by Lasonya A. Fletcher 16
17. Primary
Survey
Circulation
FluidTherapy
Crystalloid solns readily available and
inexpensive
Resuscitation requires large quantities of
crystalloids
Lactated Ringer's soln is less likely to cause
hyperchloremic acidosis than is normal saline
Dextrose-containing solns may exacerbate ischemic
brain damage
In the presence of cerebral edema, hypertonic solns
(3% or 7.5% saline) are effective for volume
resuscitation
1ºC
2013 Prepared by Lasonya A. Fletcher 17
18. Primary
Survey
Circulation
FluidTherapy
Colloids more expensive than crystalloids
but more effective in rapidly restoring
intravascular volume
Albumin is usually selected over dextran or
hetastarch due to the fear of inducing a
coagulopathy
Whichever fluid is chosen must be warmed prior to
administration.
Hypothermia worsens acid-base disorders,
coagulopathy and myocardial dysfunction. It also shifts
the oxygen-hemoglobin curve to the left and decreases
the metabolism of lactate, citrate and some anesthetic
drugs
*MonitorVital Signs!! (Blood pressure, pulse pressure and
heart rate)
1ºC
2013 Prepared by Lasonya A. Fletcher 18
19. Primary
Survey
Circulation
FluidTherapy
CentralVenous pressure and urinary output
indications of restoration of vital organ
perfusion
Inadequate organ perfusion interferes with
aerobic metabolism produces lactic acid and
metabolic acidosis
Hypotension in patients with hypovolemic
shock should be aggressively treated with IV
fluids and blood products NOT vasopressors
unless there is profound hypotension
unresponsive to fluid therapy
Shock refractory to aggressive fluid therapy
may be due to uncontrolled haemorrhage that
exceed the rate of transfusion
1ºC
2013 Prepared by Lasonya A. Fletcher 19
20. Primary
Survey
Disability
Evaluation for disability consists of a rapid
neurological assessment.
Because there is usually no time for a Glasgow
Coma Scale the AVPU system is used:
awake
verbal response
painful response
unresponsive.
1ºD
2013 Prepared by Lasonya A. Fletcher 20
21. Primary
Survey
Exposure
The patient should be undressed to allow
examination for injuries.
In-line immobilization should be used if a neck
or spinal cord injury is suspected.
1ºE
2013 Prepared by Lasonya A. Fletcher 21
23. Secondary
Survey
Begins once the ABC’s have been stabilized
Patient evaluated from head to toe and the
indicated studies carried out
Basic laboratory investigations include:
complete blood count
Electrolytes
Glucose
Blood urea nitrogen (BUN)
Creatinine
Arterial blood gases
Chest X-ray
Cross-table lateral and swimmer’s view
Skull, pelvic and long bones
Focused assessment with sonography (FAST)
CT Chest
Peritoneal lavage
2º
2013 Prepared by Lasonya A. Fletcher 23
24. Secondary
Survey
Head-toe-Assessment: Main Points
Head: injuries to scalp, eyes and ears
Neuro: Glasgow Coma Scale, evaluation of sensory and
motor function
Chest: auscultate and inspecte again for fractures
and functional integrity
Diminished breath sounds may indicate a
pneumothorax
Distant heart sounds may indicate pericardial
tamponade
Abdomen: inspection, auscultation, and palpation.
Extremities: examine for fractures, dislocations,
and peripheral pulses
A urinary catheter and nasogastric tube are also
normally inserted
2º
2013 Prepared by Lasonya A. Fletcher 24
25. Secondary
Survey
2º Eye Opening
• Spontaneous (4)
• To verbal
command (3)
• To pain (2)
• None (1)
BestVerbal
Response
• Oriented
conversation (5)
• Disoriented
conversation (4)
• Inappropriate
words (3)
• Incomprehensible
words (2)
• Incomprehensible
sounds (2)
• None (1)
Best Motor
Response
• Obeys verbal
command (6)
• Localizes painful
stimuli (5)
• Flexion withdrawal
from painful
stimuli (4)
• Decorticate
response to painful
stimuli (3)
• Decerebrate
response to painful
stimuli (2)
• None (1)
Glasgow Coma Scale
2013 Prepared by Lasonya A. Fletcher 25
27. Tertiary
Survey
Tertiary Survey defined as a patient evaluation
that identifies and catalogues all injuries after
initial resuscitation and operative
interventions.
Typically occurs within 24 h of injuries.
Delayed evaluation normally results in a more
awake patient who is able to fully communicate
all complaints, more detailed information on
the mechanism of injury, and a detailed
examination of the medical record to
determine preexisting comorbidities.
3º
2013 Prepared by Lasonya A. Fletcher 27
28. Tertiary
Survey
The tertiary survey occurs prior to discharge to
reassess and confirm known injuries and
identify occult ones.
Includes another "head-to-toe examination"
and a review of all laboratory and imaging
studies.
Missed injuries can include extremity and pelvic
fractures, spinal cord and head injuries, and
abdominal and peripheral nerve injuries
3º
2013 Prepared by Lasonya A. Fletcher 28
29. General Considerations
Head and Spinal Trauma
Chest Trauma
Abdominal Trauma
Extremity Trauma
2013 Prepared by Lasonya A. Fletcher
29
30. If a patient arrives in the operating theatre already
intubated, correct positioning of the endotracheal tube
must be verified
Patients with suspected head trauma hyperventilate to
decrease intracranial pressure
Ventilation may be compromised by pneumothorax, flail
chest, obstruction of endotracheal tube or direct
pulmonary injury
2013 Prepared by Lasonya A. Fletcher 30
31. If a patient is not intubated then proper airway
management principles should be followed.
Where possible, hypovolemia should be at least partially
corrected prior to induction.
Fluid resuscitation and transfusion should continue
throughout induction and maintenance of anaesthesia.
Commonly used induction agents for trauma patients
include ketamine and etomidate
2013 Prepared by Lasonya A. Fletcher 31
32. A 'rapid sequence
induction' is used
when a patient
requires general
anaesthesia who
has been identified
as having risk
factors for gastric
aspiration.
2013 Prepared by Lasonya A. Fletcher 32
33. Technique for Rapid Sequence Induction
1. Prepare for General Anaesthesia
2. Turn on pharyngeal suction apparatus
3. Have patient breath 100% O2
4. Position head in ‘sniffing’ position
5. Consider patient’s size, age and state of health to determine ideal
dose of induction agent. Give dose + 1mg/kg succinylcholine in
quick succession.
6. As soon as the patient has lost consciousness, apply pressure to
cricoid cartilage (Sellick’s manoeuver)
7. Reconfirm posture and intubate trachea at onset of paralysis
8. Inflate cuff of endotracheal tube before releasing cricoid pressure
9. Check position of ET tube, make adjustments and secure in place2013 Prepared by Lasonya A. Fletcher 33
34. Any trauma victim with altered consciousness must be
considered to have a brain injury
The level of consciousness is assessed by serial Glasgow
Coma Scale evaluations
Injuries requiring immediate surgical intervention:
epidural hematoma, acute subdural hematoma, some
penetrating brain injuries and depressed skull fractures.
Injuries managed conservatively: basilar skull fracture and
intracerebral hematoma.
2013 Prepared by Lasonya A. Fletcher 34
35. Basilar skull fractures are often associated
“Raccoon eyes"
Battle's sign
CSF rhinorrhea
Other signs of brain damage include restlessness, convulsions, and
cranial nerve dysfunction
The classic Cushing triad (hypertension, bradycardia, and respiratory
disturbances) is a late and unreliable sign that usually just precedes
brain herniation
Patients suspected of sustaining head trauma should not receive any
premedication that will alter their mental status or neurological
examination
2013 Prepared by Lasonya A. Fletcher 35
36. Brain injuries intracranial pressure from cerebral
haemorrhage and edema
Controlled by
fluid restriction (except in hypovolemic shock)
diuretics [0.5g/kg mannitol]
Barbiturates
Deliberate hypocapnia [PaCo2 of 28-32 mm Hg]
*Hypertension or tachycardia during intubation can be
attenuated with intravenous lidocaine or fentanyl.
2013 Prepared by Lasonya A. Fletcher 36
37. The degree of physiological derangement following spinal
cord injury is proportional to the level of the lesion.
Lesions of the cervical spine may involve the phrenic nerves
(C3–C5) and cause apnea.
Loss of intercostal function limits pulmonary reserve and the
ability to cough.
High thoracic injuries will eliminate sympathetic innervation of
the heart (T1–T4), leading to bradycardia.
Acute high spinal cord injury can cause spinal shock, a
condition characterized by loss of sympathetic tone in the
capacitance and resistance vessels below the level of the
lesion, resulting in hypotension, bradycardia, areflexia, and
gastrointestinal atony2013 Prepared by Lasonya A. Fletcher 37
38. Succinylcholine is reportedly safe during
the first 48 h following the injury but is
associated with life-threatening
hyperkalemia afterward.
Short-term high-dose corticosteroid
therapy with methylprednisolone (30
mg/kg followed by 5.4 mg/kg/h for 23h)
improves the neurological outcome of
patients with spinal cord trauma.
2013 Prepared by Lasonya A. Fletcher 38
39. Chest Trauma may severely compromise
the function of the heart or lungs,
leading to cardiogenic shock or hypoxia
Simple Pneumothorax
Tension Pneumothorax
Multiple rib fractures
Hemomediastinum
Pulmonary Contusion
Cardiac Tamponade
Anaesthetic Mx: maximize cardiac
inotropism, chronotropism and preload
Ketamine is a favored induction agent
2013 Prepared by Lasonya A. Fletcher 39
40. Chest Trauma may also result in
Myocardial contusion
Aortic transection or aortic dissection
Avulsion of the left subclavian artery
Aortic or mitral valve disruption
Traumatic diaphragmatic herniation
Esophageal rupture.
Acute respiratory distress syndrome
(ARDS) is usually a delayed pulmonary
complication of trauma that has
multiple causes: sepsis, direct thoracic
injury, aspiration, head injury, fat
embolism, massive transfusion, and
oxygen toxicity.2013 Prepared by Lasonya A. Fletcher 40
41. Patients involved in major trauma should
be considered to have an abdominal injury
until proved otherwise
Abdominal trauma is usually divided into
penetrating (eg, gunshot or stabbing) and
non-penetrating (eg, deceleration, crush, or
compression injuries).
Penetrating abdominal injuries are usually
obvious with entry marks on the abdomen
or lower chest. The most commonly injured
organ is the liver. Patients tend to fall into
three subgroups: (1) pulseless, (2)
hemodynamically unstable, and (3) stable.
2013 Prepared by Lasonya A. Fletcher 41
42. Pulseless and hemodynamically unstable
patients (those who fail to maintain a
systolic blood pressure of 80–90 mm Hg
with 1–2 L of fluid resuscitation) should be
rushed for immediate laparotomy.
Stable patients with clinical signs of
peritonitis or evisceration should also
undergo laparotomy as soon as possible
Hemodynamically stable patients with
penetrating injuries who do not have
clinical peritonitis require close evaluation
to avoid unnecessary laparotomy2013 Prepared by Lasonya A. Fletcher 42
43. Profound hypotension may follow opening of the abdomen as
the tamponading effect of extravasated blood (and bowel
distention) is lost..
Nitrous oxide is avoided to prevent worsening of bowel
distention.
A nasogastric tube (if not already present) will help prevent
gastric dilation but should be placed orally if a cribriform plate
fracture is suspected.
Massive abdominal hemorrhage may require packing of bleeding
areas and/or clamping of the abdominal aorta until bleeding
sites are identified and the resuscitation can catch up with the
blood loss.2013 Prepared by Lasonya A. Fletcher 43
44. Extremity injuries can be life-threatening because of associated
vascular injuries and secondary infectious complications.
Fat emboli are associated with pelvic and long-bone fractures and
may cause pulmonary insufficiency, dysrhythmias, skin petechiae,
and mental deterioration within 1–3 days after the traumatic event
Compartment syndrome can occur following large hematomas, crush
injuries, fractures and amputation injuries
If the injury is isolated, a regional technique (eg, brachial or
interscalene plexus block) is often recommended to increase
peripheral blood flow by interrupting sympathetic innervation.
During general anesthesia, the patient should be kept warm, and
emergence shivering must be avoided to maximize perfusion.
2013 Prepared by Lasonya A. Fletcher 44
45.
46. CASE
• A 43-YEAR-OLD MAN WHO SUFFERED A MAJOR
THERMAL BURN 7 DAYS PREVIOUSLY IS SCHEDULED
FOR EXCISION AND GRAFTING UNDER GENERAL
ANESTHESIA
2013 PREPARED BY LASONYA A.
FLETCHER
46
47. CLASSIFICATION OF BURNS
From Bailey and Love’s Short Practice of Surgery
th
• Burn injuries are described according to the percentage of
body surface area involved and the depth of the skin
destroyed.
• Survival is influenced by the percentage surface area
involved and the age of the patient.
• The rule of nines divides the body's surface area into areas
of 9% or multiples of 9%
• The surface area of one side of the patient's hand represents
1% of total body surface area.
• First-degree burns are limited to the epithelium, second-
degree burns extend into the dermis, and third-degree burns
destroy the entire skin thickness
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48. PULMONARY PATHOPHYSIOLOGY
ASSOCIATED WITH MAJOR BURN INJURIES
• Direct inhalational injury is usually limited to upper airway edema that can lead to life-
threatening airway obstruction.
• Lower airways can also be subjected to direct thermal insult (eg, steam) or can be injured by
exposure to smoke and toxic products of combustion.
• Deactivation of surfactant can lead to atelectasis and pulmonary shunting.
• Permeability can be increased throughout the entire microvascular system contribute to the
development of pulmonary edema and acute respiratory distress syndrome.
• Circumferential burns of the thorax may decrease chest wall compliance and further increase
peak inspiratory pressures
• . Carbon monoxide inhalation shifts the oxygen–hemoglobin curve to the left (interfering with
the unloading of oxygen at tissues) and decreases oxyhemoglobin saturation.
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49. CARDIOVASCULAR EFFECTS ASSOCIATED
WITH BURN INJURIES
• Increases in permeability at the site of injury and throughout the microvasculature cause
a tremendous shift of fluid from the plasma volume to the interstitial space.
• Hematocrit may rise as a result of the contraction of intravascular volume.
• Cardiac output declines as a result of the contraction of plasma volume and a circulating
myocardial depressant factor.
• If volume replacement does not provide an adequate diuresis (1 ml/kg/h), inotropic
support with dopamine may be beneficial.
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50. ELECTROLYTE DERANGEMENTS FOUND IN
BURN PATIENTS
• Hyperkalemia from tissue destruction may complicate management during the acute
resuscitation phase. Later, renal wasting and gastric losses may result in hypokalemia
• Topical antibiotic therapy may also cause electrolyte imbalances
• Electrical burns are associated with such severe muscle cell damage that myoglobinuria
can lead to renal failure.
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51. MONITORS THAT WOULD BE USEFUL DURING
THIS EXCISION AND GRAFTING PROCEDURE
• At least two large-bore intravenous lines, an arterial line, and often a central venous catheter
or pulmonary artery catheter are indicated.
• A central triple-lumen catheter can be helpful in patients with difficult intravenous access. A
noninvasive blood pressure unit should be used as a backup to the arterial line, which may
malfunction if the patient is frequently repositioned.
• Electrocardiograph skin electrodes will not stick to burned areas, and they interfere with
chest wall excision. As an alternative, needle electrodes are often sutured in place.
• Hypothermia can be minimized by using warming blankets and heat lamps, increasing
operating room temperature, humidifying inspired gases, and warming intravenous fluids.
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52. SPECIAL INTUBATION CONSIDERATIONS IN
THESE PATIENTS
• Burn victims with inhalational injury will often be intubated prior to surgery.
• Indications for early intubation include hypoxia not correctable with a face mask, upper
airway edema that may progress to obstruction, or the presence of copious secretions.
• Impending airway obstruction or severe facial contractures call for an awake fiberoptic
intubation.
• Tracheostomies have been associated with increased morbidity in burn patients because
of pulmonary sepsis.
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53. HOW DOES A BURN INJURY AFFECT THE
PHARMACOLOGY OF ANESTHETIC DRUGS?
• Succinylcholine is contraindicated in burn patients after the first 24 h. Its administration has
caused cardiac arrest because of dramatic increases in serum potassium levels.
• Burn patients require higher than normal doses of non-depolarizing muscle relaxants. This
resistance is due to altered protein binding and an increased number of extra-junctional
acetylcholine receptors, which bind non-depolarizing drug without causing a neuromuscular
effect.
• Volatile anesthetics will exacerbate myocardial depression but are useful after the acute
phase.
• Because of the potential for serious dysrhythmias, halothane is best avoided if epinephrine-
soaked bandages are being used to decrease blood loss
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54. REFERENCES
• G. Edward Morgan, Jr., Maged S. Mikhail, Michael J. Murray Clinical Anaesthesia 4th ed. 2007 The
Mcgraw-Hill Companies. Chap 41
• Sullivan, Pat Anaesthesia for Medical Students 1999 Department of Anaesthesia, Ottawa Civic Hospital
• Barash, P Handbook of Clinical Anaesthesia 6th ed. 2009 Lippincott Williams and Wilkins pp 460-478
• Gwinutt, C Lecture Notes: Clinical Anaesthesia 2nd ed. 2004 Blackwell Publishing
• Williams, N et al. Bailey and Love’s Short Practice of Surgery 25th ed. 2008. Edward Arnold
Publishers. Pp 271-394
• Bickley, L Bates’ Guide to Physical Examination and History Taking 10th ed. 2009. Lippincott Williams
and Wilkins
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