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Literature review
Type of study Prospective study
Authors Thomas J. Nuckton et. al
Date of publication March 6, 2006
Name of Journal SLEEP
 OBSTRUCTIVE SLEEP APNEA (OSA) MAY AFFECT AS MANY AS 1 IN 5
ADULTS AND HAS THE POTENTIAL FOR CAUSING SERIOUS LONG-TERM
HEALTH consequences, including cardiovascular disease, hypertension, and stroke
and a reduced quality of life.
(Young T, Peppard PE, Bixler EO, Shahar E, Malhotra A)
Introduction
Mallampati SR, Samsoon GL, Benumof JL, Pollard BJ
 The Mallampati score, derived from a simple airway-classification system, has been
used to identify patients at risk for difficult tracheal intubation for more than 20 years.
 The system is non invasive and simple to learn, and it requires no special equipment.
Introduction
 To assess the clinical usefulness of the Mallampati score in patients with obstructive
sleep apnea.
Study Objective
 All measurements, including the Mallampati score, were made prior to
polysomnography as part of a routine clinical assessment.
 The Mallampati score was obtained during the physical examination of each patient.
 For all patients, the assessment of scores was done or directly supervised by the same
physician.
.
 The score was assessed by asking the
patient to open his or her mouth as
wide as possible, while protruding the
tongue as far as possible.
 The patient was instructed to not emit
sounds during the assessment.
 A standard I to IV grading system was
used.
1. Class I: Soft palate, uvula visible.
2. Class II: Soft palate, portion of uvula
visible.
3. Class III: Soft palate, base of uvula
visible.
4. Class IV: Only hard palate visible (
soft palate not visible)
 A modified Mallampati score, obtained without protruding the tongue but that is
otherwise identical to standard scoring, was also assessed.
Friedman M and Zonato AI et. al
 The Epworth Sleepiness Scale (ESS) was used to assess subjective sleepiness.
 Scores range from 0 to 24, and higher scores indicate a higher propensity toward
daytime sleepiness.
Johns MW and Chervin RD
 The primary outcome variables were OSA and the apnea-hypopnea index (AHI), as
determined by polysomnography.
 OSA was defined as an AHI of 5 or greater.
 The AHI refers to the total number of episodes of  either cessation (apnea) or
decrease in airflow (hypopnea) per hour.
 Apnea was determined by  a cessation of airflow for 10 or more seconds.
 Hypopnea was determined by  a decrease in airflow combined with a 4% or greater
decrease in oxygen saturation.
 Neck circumference, witnessed apnea, and hypertension were the only other
variables that  were independently associated with an increased risk of OSA.
 Age, neck circumference, and severity of witnessed apnea  were also
independently associated with the AHI.
 There were no significant associations between Mallampati score and either body
mass index (p = .2), tonsil size (p = .3), use of home polysomnography (p = .7), or
patient age (p = .9).
 There were significant but modest associations between Mallampati score and neck
circumference (r = 0 .19; p = .03) and Mallampati score and degree of overjet (r = 0 .21;
p = .01).
Discussion
 On average, for every 1-point increase in Mallampati score  the odds of having
OSA increased more than 2-fold and the AHI increased by more than 5 events per
hour.
 Moreover, these associations were independent of all other variables that we
measured, including history of snoring, overjet, tonsil size, neck circumference, and
body mass index.
Discussion
 Indeed, an association between difficulty of tracheal intubation and OSA has been
reported.
 The original Mallampati score was based on  a scale of I to III but, over time,
has evolved into  the I to IV scoring system  used commonly by
anesthesiologists today  to assess the difficulty of endotracheal intubation.
 In this study, the proportions of patients with OSA were similar in those with a
Mallampati score of III or IV.
Discussion
 However, the average AHI was higher in patients with a Mallampati score of IV,
and, in our regression models, both the AHI and the odds of having OSA increased
as Mallampati score increased.
 Mallampati scoring could also be used  to prioritize patients for polysomnography,
an important consideration given the large backlog of patients awaiting assessment
for OSA.
Discussion
Rahaghi F, Escourrou P, Flemons WW and Pack AI.
 The Mallampati score, while having limitations as a diagnostic test, is a useful part of
the physical examination of patients prior to polysomnography.
 The independent association between Mallampati score and the presence and severity of
OSA suggests that this scoring system will have practical value in clinical settings and
in prospective studies of sleep-disordered breathing.
Summary
Post-orthodontic Periodontal Treatment
After orthodontic treatment, the patient should remain on a 3 month periodontal maintenance program.
A nightguard is indicated to control parafunction and can also be used as a post-orthodontic retainer.
Occlusal adjustment to diminish any fremitus from lateral interferences
Take a new set of periapical radiographs.
It takes at least 6 months after band removal for adequate bone remodeling and cessation of mobility.

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Physical examination : Mallampati score as an independent predictor of obstructive sleep apnea by Thomas J. Nuckton et. al ppt

  • 2. Type of study Prospective study Authors Thomas J. Nuckton et. al Date of publication March 6, 2006 Name of Journal SLEEP
  • 3.  OBSTRUCTIVE SLEEP APNEA (OSA) MAY AFFECT AS MANY AS 1 IN 5 ADULTS AND HAS THE POTENTIAL FOR CAUSING SERIOUS LONG-TERM HEALTH consequences, including cardiovascular disease, hypertension, and stroke and a reduced quality of life. (Young T, Peppard PE, Bixler EO, Shahar E, Malhotra A) Introduction
  • 4. Mallampati SR, Samsoon GL, Benumof JL, Pollard BJ  The Mallampati score, derived from a simple airway-classification system, has been used to identify patients at risk for difficult tracheal intubation for more than 20 years.  The system is non invasive and simple to learn, and it requires no special equipment. Introduction
  • 5.  To assess the clinical usefulness of the Mallampati score in patients with obstructive sleep apnea. Study Objective
  • 6.  All measurements, including the Mallampati score, were made prior to polysomnography as part of a routine clinical assessment.  The Mallampati score was obtained during the physical examination of each patient.  For all patients, the assessment of scores was done or directly supervised by the same physician. .
  • 7.  The score was assessed by asking the patient to open his or her mouth as wide as possible, while protruding the tongue as far as possible.  The patient was instructed to not emit sounds during the assessment.  A standard I to IV grading system was used.
  • 8. 1. Class I: Soft palate, uvula visible. 2. Class II: Soft palate, portion of uvula visible. 3. Class III: Soft palate, base of uvula visible. 4. Class IV: Only hard palate visible ( soft palate not visible)
  • 9.  A modified Mallampati score, obtained without protruding the tongue but that is otherwise identical to standard scoring, was also assessed. Friedman M and Zonato AI et. al
  • 10.  The Epworth Sleepiness Scale (ESS) was used to assess subjective sleepiness.  Scores range from 0 to 24, and higher scores indicate a higher propensity toward daytime sleepiness. Johns MW and Chervin RD
  • 11.  The primary outcome variables were OSA and the apnea-hypopnea index (AHI), as determined by polysomnography.  OSA was defined as an AHI of 5 or greater.
  • 12.  The AHI refers to the total number of episodes of  either cessation (apnea) or decrease in airflow (hypopnea) per hour.  Apnea was determined by  a cessation of airflow for 10 or more seconds.  Hypopnea was determined by  a decrease in airflow combined with a 4% or greater decrease in oxygen saturation.
  • 13.  Neck circumference, witnessed apnea, and hypertension were the only other variables that  were independently associated with an increased risk of OSA.  Age, neck circumference, and severity of witnessed apnea  were also independently associated with the AHI.
  • 14.  There were no significant associations between Mallampati score and either body mass index (p = .2), tonsil size (p = .3), use of home polysomnography (p = .7), or patient age (p = .9).  There were significant but modest associations between Mallampati score and neck circumference (r = 0 .19; p = .03) and Mallampati score and degree of overjet (r = 0 .21; p = .01).
  • 15. Discussion  On average, for every 1-point increase in Mallampati score  the odds of having OSA increased more than 2-fold and the AHI increased by more than 5 events per hour.  Moreover, these associations were independent of all other variables that we measured, including history of snoring, overjet, tonsil size, neck circumference, and body mass index.
  • 16. Discussion  Indeed, an association between difficulty of tracheal intubation and OSA has been reported.  The original Mallampati score was based on  a scale of I to III but, over time, has evolved into  the I to IV scoring system  used commonly by anesthesiologists today  to assess the difficulty of endotracheal intubation.  In this study, the proportions of patients with OSA were similar in those with a Mallampati score of III or IV.
  • 17. Discussion  However, the average AHI was higher in patients with a Mallampati score of IV, and, in our regression models, both the AHI and the odds of having OSA increased as Mallampati score increased.
  • 18.  Mallampati scoring could also be used  to prioritize patients for polysomnography, an important consideration given the large backlog of patients awaiting assessment for OSA. Discussion Rahaghi F, Escourrou P, Flemons WW and Pack AI.
  • 19.  The Mallampati score, while having limitations as a diagnostic test, is a useful part of the physical examination of patients prior to polysomnography.  The independent association between Mallampati score and the presence and severity of OSA suggests that this scoring system will have practical value in clinical settings and in prospective studies of sleep-disordered breathing. Summary
  • 20. Post-orthodontic Periodontal Treatment After orthodontic treatment, the patient should remain on a 3 month periodontal maintenance program. A nightguard is indicated to control parafunction and can also be used as a post-orthodontic retainer. Occlusal adjustment to diminish any fremitus from lateral interferences Take a new set of periapical radiographs. It takes at least 6 months after band removal for adequate bone remodeling and cessation of mobility.

Editor's Notes

  1.  is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who differ with respect to certain factors under study, to determine how these factors affect rates of a certain outcome. The prospective study is important for research on the etiology of diseases and disorders. 
  2. Tracheal intubation, usually simply referred to as intubation, is the placement of a flexible plastic tube into the trachea (windpipe) to maintain an open airway or to serve as a conduit through which to administer certain drugs
  3. Patients of at least 18 years of age referred to the University of California, San Francisco Sleep Disorders Center and evaluated for possible OSA were eligible for the study ========================================== We studied 137 patients with suspected OSA and who had been referred to the University of California Sleep Disorders Center
  4. Pillars
  5. The Epworth Sleepiness Scale (ESS) is a scale[1][2] intended to measure daytime sleepiness that is measured by use of a very short questionnaire. This can be helpful in diagnosing sleep disorders. It was introduced in 1991 by Dr Murray Johns of Epworth Hospital in Melbourne, Australia.[3
  6. Polysomnography a type of sleep study[1], is a multi-parametric test used in the study of sleep and as a diagnostic tool in sleep medicine.  Polysomnography, also called a sleep study, is a test used to diagnose sleep disorders. Polysomnography records your brain waves, the oxygen level in your blood, heart rate and breathing, as well as eye and leg movements during the study.
  7. نماذج الانحدار regression models,
  8. Backlog = As IOTN