A carbuncle is a cluster of boils caused by Staphylococcus aureus infection of the subcutaneous tissue, commonly occurring in diabetic patients or those with poor immunity. It presents as a red, swollen, and painful nodule typically on the neck, back or shoulders. Risk factors include diabetes, poor hygiene, weak immune system, and activities that break the skin. Treatment involves antibiotics, pain medication, improving health, and potentially surgery to drain pus if it forms pockets.