Gas gangrene is a deep wound infection caused by Clostridium bacteria that destroys tissue. Symptoms include high fever, shock, massive tissue destruction, blackening of skin around the wound, severe pain, and blisters forming with gas bubbles. Those at risk are people with diabetes, blood vessel disease, or colon cancer, or those with wounds exposed to contaminated materials or recent trauma. Treatment involves high doses of antibiotics like penicillin, removing dead tissue, or amputating limbs. Prevention includes cleaning wounds, avoiding contamination, and treating circulation issues.

1. GAS GANGRENE

2. Gas Gangrene What is GAS GANGRENE?? - A deep wound infection,destructive of tissue, often caused by combination of two or more species.

3. Symptoms High fever Shock Massive tissue destruction Blackening of skin Severe pain around a skin of wound Blisters with gas bubbles form near the infected area, the heartbeat and breathing become rapid.

4. Causative agent Clostribium species

5. Pathogenesis

6. Epidemiology The persons at risk those with Diabetes Mellitus, blood vessel disease and colon cancer Contact with contaminated cloth and other foreign material Trauma or recent surgical wound

7. Treatment High doses of antibiotic : Penicillin The dead tissue is removed or limbs are amputated No vaccine

8. Prevention Cleaning the wound Avoid the contaminated material impaired circulation in patients with poor circulation Treatment with hyperbaric oxygen- to treat the gas gangrene antitoxin