1. The document discusses the side effects of calcium supplements, including how calcium is absorbed in the body through both active and passive mechanisms that can be affected by various factors. 2. Potential side effects include hypercalcemia, kidney stone formation, constipation, and studies have found increased risk of myocardial infarction with calcium supplement use. 3. The document reviews several studies on the relationships between calcium intake, cardiovascular risks, and coronary artery calcification, finding no clear evidence that calcium supplements significantly increase heart risks.

2. Qom University of Medical Sciences And Health Services
Medical School
Side Effects Of Calcium Supplements
Supervisor:Dr.A.Heidari
Provisioner:Mohammad Mahdi Shater

5. ‫شود‬ ‫می‬‫جذب‬‫ده‬‫و‬‫ر‬ ‫های‬ ‫قسمت‬ ‫تمام‬ ‫در‬
‫فعال‬ ‫غیر‬ ‫و‬ ‫فعال‬ ‫مکانیسم‬‫دو‬ ‫با‬‫جذب‬
‫جذب‬ ‫بر‬ ‫موثر‬ ‫عوامل‬
‫غذا‬‫با‬ ‫اه‬‫ر‬‫هم‬ ‫کلسیم‬‫مکمل‬ ‫مصرف‬‫بیشتر‬ ‫اثر‬

6. ‫مدفوع‬ ‫و‬‫ار‬‫ر‬‫اد‬ ‫طریق‬ ‫از‬ ‫دفع‬
‫ندگی‬‫ز‬ ‫ل‬‫طو‬‫در‬ ‫ی‬‫ار‬‫ر‬‫اد‬ ‫دفع‬ ‫ان‬‫ز‬‫می‬‫تفاوت‬
‫شد‬‫ر‬ ‫ان‬‫ر‬‫دو‬/‫یائسگی‬‫ان‬‫ر‬‫دو‬/‫از‬ ‫پس‬65‫سال‬
Hypercalciuria

9. ‫مطالعه‬‫در‬‫د‬‫ر‬‫مو‬‫دختران‬‫نوجوان‬‫نشان‬‫داد‬‫یافت‬‫ر‬‫د‬
‫انه‬‫ز‬‫و‬‫ر‬1300‫میلی‬‫گرم‬‫کلسیم‬‫برای‬‫حداکثر‬‫سوب‬‫ر‬
‫کلسیم‬‫در‬‫استخوان‬‫های‬‫بدن‬‫ی‬‫ر‬‫و‬‫ضر‬‫است‬

10. ‫براساس‬‫تحقیقات‬‫در‬‫سال‬2005‫مکمل‬‫کلسیم‬‫برای‬
‫کودکان‬‫و‬‫نوجوانان‬‫مفید‬‫است‬.
‫آگاهی‬‫کمتر‬‫در‬‫د‬‫ر‬‫مو‬‫نیاز‬‫آقایان‬‫به‬‫کلسیم‬

13. ‫ها‬ ‫آمریکایی‬ ‫غذایی‬‫یم‬‫ژ‬‫ر‬ ‫در‬‫معدنی‬ ‫مواد‬‫مشکل‬
‫میانگین‬‫یافت‬‫ر‬‫د‬‫غذایی‬‫کلسیم‬‫در‬‫آمریکا‬‫با‬‫ع‬‫و‬‫شر‬11‫سالگی‬‫تا‬
‫حد‬‫قابل‬‫مالحظه‬‫ای‬‫از‬‫مقدار‬‫یافت‬‫ر‬‫د‬‫کافی‬‫کمتر‬‫است‬.

14. ‫کلسیم‬ ‫کمبود‬
• Osteomalacia
• Rachitisme
• Osteoprosis
• Hypertension
• Cancer of colon
• Hypocalcemia

16.  Hypercalcemia
 Calcification(soft tissue & kidney)
‫ساملندی‬ ‫در‬ ‫استخوان‬‫شکستگی‬
‫منگنز‬،‫ی‬‫و‬‫ر‬ ،‫آهن‬ ‫ظرفیتی‬‫دو‬‫های‬‫ن‬‫کاتیو‬‫جذب‬ ‫در‬‫مداخله‬

17. Constipation
‫است‬‫شایع‬ ‫کنند‬ ‫می‬ ‫استفاده‬ ‫کلسیم‬ ‫مکمل‬ ‫که‬‫ساملند‬ ‫نان‬‫ز‬ ‫در‬

18. Calcium and cardiovascular disease
Associations of dietary calcium intake and calcium
supplementation with myocardial infarction and stroke
risk and overall cardiovascular mortality
Results 354 MI
260 stroke cases
267 CVD deaths
Compared with the lowest quartile, the third quartile
of total dietary and dairy calcium intake had a
significantly reduced MI risk . Associations for stroke
risk and CVD mortality were overall null
June 2012
Users of calcium supplements had a statistically
significantly increased MI risk.
Conclusions: Increasing calcium intake from diet
might not confer significant cardiovascular benefits,
while calcium supplements, which might raise MI risk,
should be taken with caution.

19. Calcium intake is not associated with increased coronary
artery calcification
•Objective: We assessed the association between calcium
intake (from diet and supplements) and coronary artery
calcification
•Conclusions: Our study does not support this hypothesis
December 2012

20. Harvard Says Calcium Supplements Are Safe
For Heart Health
•A study published in British medical journal in 2010 caused
considerable concern by saying that taking calcium
supplements could increase arterial plaque and the risk of
heart attacks.
•Result: Our study do not support a significant detrimental
effect of calcium intake on coronary artery calcification
November 2012

21. ‫منابع‬
•‫کراوس‬‫تغذیه‬ ‫کلی‬ ‫ل‬‫اصو‬
•‫دودک‬‫مانی‬‫ر‬‫د‬‫تغذیه‬ ‫و‬ ‫تغذیه‬
• http://hms.harvard.edu/
• http://heart.bmj.com/
• http://ajcn.nutrition.org/

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