HPV RELATED DISEASES
Human papillomavirus (HPV) infection is now a well-established cause of cervical cancer. HPV causes virtually 100% of cervical cancer cases
There is growing evidence of HPV being a relevant factor in other ANOGENITAL CANCERS (anus, vulva, vagina and penis) and head and neck cancers.
HPV is also responsible for other diseases such as recurrent juvenile respiratory papillomatosis and genital warts
UPDATE HPV Vaccination IN Cervical Cancer Prevention Dr Sharda Jain Lifecare Centre
Cervical Cancer In India: A Preventable Tragedy That Requires Urgent Attention
It is estimated that in India, about 160 million women aged 30-59 years are at risk of developing cervical cancer, with fatality rate of 50 per cent
HPV Infection , HPV Vaccination , Cervical cancer , Cancer in India , Dr. SHA...Lifecare Centre
HPV inefection , HPV disease prevention, Cervical cancer prevention , Cervical cancer treatment, Female cancer , Female cancer prevention , Uterine cancer , Cancer in india
UPDATE HPV Vaccination IN Cervical Cancer Prevention Dr Sharda Jain Lifecare Centre
Cervical Cancer In India: A Preventable Tragedy That Requires Urgent Attention
It is estimated that in India, about 160 million women aged 30-59 years are at risk of developing cervical cancer, with fatality rate of 50 per cent
HPV Infection , HPV Vaccination , Cervical cancer , Cancer in India , Dr. SHA...Lifecare Centre
HPV inefection , HPV disease prevention, Cervical cancer prevention , Cervical cancer treatment, Female cancer , Female cancer prevention , Uterine cancer , Cancer in india
Say no to cervical cancer-PUBLIC Awareness-Life Care Centre_Dr.Sharda JainLifecare Centre
Cervical Cancer in INDIA
Say no to cervical cancer
Dr.Sharda Jain
Life Care Centre
PUBLIC Awareness_Dr.Sharda Jain
HPV Infection
HPV Vaccination
Cervical Screening
SEE & TREAT Programme tp Prevent Cervical Cancer
HPV Vaccination, Cerviocal Cancer : Do we need it
for Prevention of cervical cancer &
other HPV related diseasesm,
Presentation Outlines
Cervical cancer disease burden
Prevention with HPV vaccination
Vaccination of sexually active women
Opportunity of Postpartum HPV vaccination
Importance of genital warts prevention
Real world effectiveness data
Safety of HPV vaccine
HPV Diseases More Than Cervical Cancer, Dr. Sharda Jain Lifecare Centre
HPV Disease . Cervical cancer , prevention cervical cancer , HPV prevention , cancer prevention , Human Papillomavirus (HPV), cervical cancer prevention
Papillomavirus is affected by Papillomas and mucosal epithelia in humans and animals. It is about transmission, testing, symptoms, prevention, vaccines.
Healthy Savings. Medical Technology and the Economic Burden of DiseaseRevital (Tali) Hirsch
As America ages and sedentary lifestyles and unhealthy diets become more common, experts agree the nation is suffering a sharp rise in the prevalence of chronic disease. As the 21st century unfolds, technology – in the form of advanced diagnostic and therapeutic devices -- can meet the need for early detection and more effective management of illness. Some researchers, however, have questioned whether the overall benefit of technical advances outweighs the costs -- a question this report definitively answers.
Accordingly, researchers at the Milken Institute undertook a comprehensive, quantitative documentation of medical technology's impact on the economic burden of disease. The study also projects how future innovation in this sector would affect the health care system and the larger economy -- a positive benefit of more than $23 billion a year for the United States.
The study takes a systematic approach to documenting the full costs and broader economic benefits of health care investments by examining innovations pertaining to four prevalent causes of disability and death: heart disease, diabetes, colorectal cancer, and musculoskeletal disease. The report considers therapeutics and diagnostic devices that are widely used and have substantially affected the lives of patients as well as the overall U.S. economy. Among the 10 devices or device-based procedures studied are pacemakers, insulin infusion pumps, colonoscopies, and joint replacement surgery.
The data demonstrate that the use of medical technology brings considerable economic benefits. These are seen in both aggregate savings in treatment expenditures and prevention as well as the reduction of "indirect impact" through larger contributions to the economy.
Say no to cervical cancer-PUBLIC Awareness-Life Care Centre_Dr.Sharda JainLifecare Centre
Cervical Cancer in INDIA
Say no to cervical cancer
Dr.Sharda Jain
Life Care Centre
PUBLIC Awareness_Dr.Sharda Jain
HPV Infection
HPV Vaccination
Cervical Screening
SEE & TREAT Programme tp Prevent Cervical Cancer
HPV Vaccination, Cerviocal Cancer : Do we need it
for Prevention of cervical cancer &
other HPV related diseasesm,
Presentation Outlines
Cervical cancer disease burden
Prevention with HPV vaccination
Vaccination of sexually active women
Opportunity of Postpartum HPV vaccination
Importance of genital warts prevention
Real world effectiveness data
Safety of HPV vaccine
HPV Diseases More Than Cervical Cancer, Dr. Sharda Jain Lifecare Centre
HPV Disease . Cervical cancer , prevention cervical cancer , HPV prevention , cancer prevention , Human Papillomavirus (HPV), cervical cancer prevention
Papillomavirus is affected by Papillomas and mucosal epithelia in humans and animals. It is about transmission, testing, symptoms, prevention, vaccines.
Healthy Savings. Medical Technology and the Economic Burden of DiseaseRevital (Tali) Hirsch
As America ages and sedentary lifestyles and unhealthy diets become more common, experts agree the nation is suffering a sharp rise in the prevalence of chronic disease. As the 21st century unfolds, technology – in the form of advanced diagnostic and therapeutic devices -- can meet the need for early detection and more effective management of illness. Some researchers, however, have questioned whether the overall benefit of technical advances outweighs the costs -- a question this report definitively answers.
Accordingly, researchers at the Milken Institute undertook a comprehensive, quantitative documentation of medical technology's impact on the economic burden of disease. The study also projects how future innovation in this sector would affect the health care system and the larger economy -- a positive benefit of more than $23 billion a year for the United States.
The study takes a systematic approach to documenting the full costs and broader economic benefits of health care investments by examining innovations pertaining to four prevalent causes of disability and death: heart disease, diabetes, colorectal cancer, and musculoskeletal disease. The report considers therapeutics and diagnostic devices that are widely used and have substantially affected the lives of patients as well as the overall U.S. economy. Among the 10 devices or device-based procedures studied are pacemakers, insulin infusion pumps, colonoscopies, and joint replacement surgery.
The data demonstrate that the use of medical technology brings considerable economic benefits. These are seen in both aggregate savings in treatment expenditures and prevention as well as the reduction of "indirect impact" through larger contributions to the economy.
Human papillomavirus (HPV) causes cervical cancer being the fourth most common cancer in women. 99% of all cervical cancer cases are related to genital infection with HPV. HPV Vaccines are now available and are the springboard for a change by primary prevention of this threatening situation.
HPV primary Screening is an tempting option for health providers and patients because the results are not subject to inter-observer variation. HPV screening might become cheaper than cytology in the future. Costs of Human resources HPV primary screening is an attractive option to health service managers because the results are not subject to inter-observer variation. Future HPV screening might be cheaper than cytology. Human resources and quality controling means might become even lower.
Nevertheless, HPV testing also requires equipment, reagents, training, quality control and accreditation - and sensitivity and specificity of different HPV tests is known to vary costs quality control may be lower.
Nevertheless, HPV testing also requires equipment, reagents, training, quality control and accreditation - and sensitivity and specificity of different HPV tests is known to vary
HPV Testing is essential in the triage of ASC-US and/or LSIL cytology. The test helps to clearify the situation after treatment of high-grade CIN and to resolve uncertainties after diagnostic and or consecutive treatment. 2016 up to date information is give by the presentation.
Primary HPV testing or co-testin
What is Human Papillomavirus (HPV)? Infections and Prevention | The Lifescien...The Lifesciences Magazine
Human Papillomavirus (HPV) stands as a dynamic and diverse family of viruses, offering both benign encounters and the potential for severe health implications.
Genotypes and Associated Risk Levels of Human Papilloma Virus among Female Pa...IIJSRJournal
Background: Human papillomavirus is the main factor in the etiology of cervical cancer, with over 99.7% of cases being associated with high-risk human papillomavirus infection. Although the majority of HPV infections are asymptomatic and self-limiting, persistent HPV infection can result in genital warts, oropharyngeal cancer, and cervical cancer in women, in addition to various anogenital malignancies and other genital warts in both men and women.
Method: This was a cross-sectional descriptive study which employed a convenience sampling technique where both qualitative and quantitative methods were used for data collection. A total of 374 participants were enrolled in the study and a semi structured questionnaire was administered to collect socio-demographic, reproductive and sexual history data. Laboratory analysis involved detection of HPV DNA hybrids with a chemiluminescent substrate, Digene Hybrid Capture 2 technology. Descriptive and inferential (logistic regression) analyses at level of significant (α=0.05) were used to summarize the data, and results illustrated using charts and tables.
Results: The study findings reported a significant risk level of human papillomavirus among female of age group 40-49 years (AOR; 0.15, 95% CI: 0.03-0.79; p = 0.026). Furthermore, in bivariate logistic regression the circulating HPV genotypes among the respondents was significantly characterized among women of the same age group (95% CI; 0.09-0.7; p = 0.008) as well as in the multivariate regression (AOR = 0.13; 95% CI: 0.02-0.72; p = 0.019).
Conclusion: The study thus concluded that there is 23/94 (25.67%) risk of developing cervical cancer due to high risk level HPV (with the presence of low risk level HPV 71/94 (74.33%) known for causing various forms of warts. Therefore, there is need for combined efforts from the Ministry of health and stakeholders to avail and train health care workers on the usage of HPV DNA kits to ensure timely detection of low and high-risk levels HPV. This will ensure timely identification of women at increased risk for the development of cervical cancer, thereby reducing mortality rate.
Cervical cancer global burden and where do we stand todayNiranjan Chavan
Cervical cancer is the 4th most common cancer in women worldwide but most common cause of cancer related death in India.
All over the world, including India, there is decreasing trend of cervical cancer.
26th International Papillomavirus Conference: Satellite Symposium
Enhancing HPV Prevention among Indigenous Populations: International Perspectives on Health and Well-Being
Montreal, Quebec
July 5, 2010
Opening Address
The Newer Concepts In Endometriosis Management : Dr Sharda JainLifecare Centre
The Newer Concepts In
Endometriosis Management
ENDOMETRIOSIS IS ENIGMA
DIAGNOSTIC DELEMMA
DEBILITATING DISEASE QOL
PROGRESSIVE DISEASE
RECURRENCE IS BIG PROBLEM
NO FINAL VERDICT ON CAUSE
NO PERMANENT CURE
The exact prevalence of endometriosis is unknown, but estimates 10% in the general female population in India but up to 50% in infertile women
The Newer Concepts for Reduced Surgery to preserve fertility in Endometrios...Lifecare Centre
The Newer Concepts for Reduced Surgery to preserve fertility in Endometriosis
ENDOMETRIOSIS IS ENIGMA
DIAGNOSTIC DILEMMA
DEBILITATING DISEASE QOL
PROGRESSIVE DISEASE
RECURRENCE IS BIG PROBLEM
NO FINAL VERDICT ON CAUSE
NO PERMANENT CURE
The exact prevalence of endometriosis is unknown, but estimates 10% in the general female population in India but up to 50% in infertile women
Anemia Free India Gynaecologist to focuss on *12gm Haemoglobin at Delivery I...Lifecare Centre
Important Highlights
Prophylactic Iron and Folic Acid Supplementation in all six target age groups.
Intensified year-round Behaviour Change Communication (BCC) Campaign for:(a) improving compliance to IFA and deworming, (b) enhancing appropriate infant and young child feeding practices, (c) encouraging increase in intake of iron-rich food through diet and/or fortified foods (d) ensuring delayed cord clamping .
Testing and treatment of anaemia, using digital methods and point of care treatment, with special focus on pregnant women and school-going adolescents.
Addressing non-nutritional causes of anaemia
in endemic pockets with special focus on malaria, hemoglobinopathies and fluorosis
Strategies for Improving Success Rates in ART PARTLifecare Centre
Strategies for Improving Success Rates in ART
Part - 2
Strategies for Improving Success Rates in ART
Tailoring Controlled Ovarian Stimulation
Strategies for Luteal Phase in ART cycles
Endometrial Receptivity Array
How to optimize success rates in ART? : Dr Sharda JainLifecare Centre
How to optimize success rates in ART? : Dr Sharda Jain
How to improve success rates in ART?
The big debate कार्य में आनंद
Evolution of In-vitro Fertilization (IVF)
Factors Influencing IVF Success Ist Part
Strategies for Improving Success Rates in ART Second Part
Innovations & Breakthroughs in IVF Part Three
OPEN DEBATE
SOCIALEGG FREEZING : Dr Poorva Bhargav and Dr Sharda JainLifecare Centre
SOCIALEGG FREEZING : Dr Poorva Bhargav and Dr Sharda Jain
Introduction
Social egg freezing (oocyte cryopreservation for non-medical reasons) has evolved as a proactive option for women looking to extend their reproductive possibilities past their peak childbearing years
It is the process of saving or protecting eggs, or reproductive tissues so that a person can use them to have biological children in future
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
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You can contact me on Telegram or Threema
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Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
The POPPY STUDY (Preconception to post-partum cardiovascular function in prim...
Burden of Cervical Cancer & other HPV Related Diseases : Indian Perspective . Dr. Sharda Jain Lifecare Centre
1. Burden of
Cervical Cancer
& other
HPV Related Diseases : Indian
Perspective
DR. SHARDA JAIN
ISO 14001:2004 (EMS)
…..Caring hearts, healing hands
2. HPV RELATED DISEASES
• Human papillomavirus (HPV) infection is now a
well-established cause of cervical cancer. HPV
causes virtually 100% of cervical cancer cases
• There is growing evidence of HPV being a relevant
factor in other ANOGENITAL CANCERS (anus, vulva,
vagina and penis) and head and neck cancers.
• HPV is also responsible for other diseases such as
recurrent juvenile respiratory papillomatosis and
genital warts
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz
J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in India. Summary Report 2015-12-23. [Accessed on 2016-04-20
from http://hpvcentre.net/statistics/reports/IND.pdf]
3. Cervical Cancer Worldwide
Disease Burden
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J,
Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in the World. Summary Report 2015-12-23. [Accessed on 2016-04-
20 from http://hpvcentre.net/statistics/reports/XWX.pdf]
5,27,624
New cases annually
(estimations for 2012)
4th
Common cause of female
cancer
2nd
Most common female
cancer in women aged 15-
44 years
4. 4
2,65,672
Deaths
Annually
Approx. 728 women die every day
A women is dies every 2 minutes
Approx. 30 women die every hour
CERVICAL CANCER MORTALITY WORLDWIDE
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz
J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in the World. Summary Report 2015-12-23. [Accessed on 2016-04-
20 from http://hpvcentre.net/statistics/reports/XWX.pdf]
4th Cause in female cancer deaths and 2nd most
common cancer deaths in women
aged 15-44 years
5. CERVICAL CANCER DISEASE BURDEN IN INDIA
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R,
Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information
Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-12-23. [Accessed on
2016-04-20 from http://hpvcentre.net/statistics/reports/IND.pdf]
1,22,844 New cases annually
2nd
Common cause of
female cancer
2nd Most common female cancer in
women aged 15-44 years
• India has a population of 436.76 million women aged 15
years and older who are at risk of developing cervical cancer.
• India accounts for ~ 1/4th of Cervical cases and deaths
worldwide
6. 6
67,477
Deaths
Annually
Approx. 185 women die every day
A women is dies every 8 minutes
Approx. 8 women die every hour
CERVICAL CANCER MORTALITY IN INDIA
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R,
Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV
Information Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-12-23.
[Accessed on 2016-04-20 from http://hpvcentre.net/statistics/reports/IND.pdf]
2nd Cause in female cancer deaths and 2nd leading
cause of cancer deaths in women
aged 15-44 years
7. Mortality Rate compared to other cancers
in Indian women
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J,
Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in India. Summary Report 2015-12-23. [Accessed on 2016-04-20 from
http://hpvcentre.net/statistics/reports/IND.pdf]
8. 8
Rajesh Dikshit etal - Lancet 2012; 379: 1807–16
Cervical cancer mortality not much
different in urban and rural Indian women
Difference in cervical cancer Mortality amongst Rural
(16.6%) & Urban (14.3%) is not very significant
9. Cervical cancer affects Women in their PRIME when
they are needed most by the family
Rates per 100,000 women per year
Annual number of cases and age-specific incidence rates of
cervical cancer in India
The Incidence of
Cervical cancer in
India is highest
amongst 40-64 yrs
women
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de
Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and
Related Diseases in India. Summary Report 2015-12-23. [Accessed on 2016-04-20 from
http://hpvcentre.net/statistics/reports/IND.pdf]
10. ADULT WOMEN AT RISK OF HPV
10
1. Insinga RP. Clin Inf Dis. 2003;36:1397-1403.
High Risk Zone for Cervical
Cancer
11. CERVICAL CANCER AND HPV TYPES
• HPV types 16 and 18 are responsible for about
70% of all cervical cancer cases worldwide. After
HPV16/18, the six most common cervical cancer
causing HPV types are 31, 33, 35, 45, 52 and 58
• In India 82.7% of invasive cervical cancers are
attributed to HPVs 16 or 18.
• In India about 5.0% of women in the general
population are estimated to harbor cervical
HPV-16/18 infection at a given time
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J,
Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre). Human
Papillomavirus and Related Diseases in India. Summary Report 2015-12-23. [Accessed on 2016-04-20 from
http://hpvcentre.net/statistics/reports/IND.pdf]
12. ANOGENITAL CANCERS OTHER THAN
THE CERVIX
• There is an increasing body of evidence strongly
linking HPV DNA with cancers of anus, vulva,
vagina, and penis.
• Although these cancers are much less frequent
compared to cervical cancer, their association with
HPV make them potentially preventable and subject
to similar preventative strategies as those for
cervical cancer
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO
Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-03- 20.
[Accessed on 1st July 2015]
13. VULVAR CANCER
• Rare among women worldwide
• An estimated 27,000 new cases in 2008,
representing 4% of all gynecologic cancers
• Worldwide, about 60% of all vulvar cancer cases
occur in more developed countries.
• HPV attribution for vulvar cancer is 43% worldwide
• HPV 16 is the most common detected type followed
by HPV 33
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S,
Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in India.
Summary Report 2015-03- 20. [Accessed on 1st July 2015]
14. VULVAR CANCER
Incidence rates of vulvar cancer by age group in India
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J,
Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in India. Summary Report 2015-03- 20. [Accessed on 1st July 2015]
15. VAGINAL CANCER
• Cancer of the vagina rare.
• An estimated 13,000 new cases in 2008, representing 2% of
all gynecologic cancers
• Majority of vaginal cancer cases (68%) occur in less
developed countries
• Most vaginal cancers are squamous cell carcinoma (90%)
generally attributable to HPV
• HPV DNA is detected among 70% of invasive vaginal
carcinomas and 91% of high-grade vaginal neoplasias
• HPV16 is the most common type in high grade vaginal
neoplasias and it is detected in at least 70% of HPV-positive
carcinomas
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R,
Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV
Information Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-03- 20.
[Accessed on 1st July 2015]
16. VAGINAL CANCER
Incidence rates of vaginal cancer by age group in India
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena
M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on
HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in
India. Summary Report 2015-03- 20. [Accessed on 1st July 2015]
17. PENILE CANCER
• Annual burden of penile cancer has been estimated
to be 22,000 cases worldwide
• Penile cancer is rare and most commonly affects
men aged 50-70 years
• Approximately 60-100% of PeIN lesions are HPV
DNA positive
• HPV DNA is detectable in approximately 50% of all
penile cancers
• HPV16 is the most common type detected, followed
by HPV18 and HPV types 6/11
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R,
Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV
Information Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-03- 20.
[Accessed on 1st July 2015]
18. PENILE CANCER
Incidence rates of penile cancer by age group in India
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena
M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on
HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases
in India. Summary Report 2015-03- 20. [Accessed on 1st July 2015]
19. HEAD AND NECK CANCERS
• Infection by certain high-risk types of human
papillomavirus (i.e. HPV16) have been reported to
be associated with head and neck cancers, in
particular with oropharyngeal cancer
• Current evidence suggests that HPV16 is associated
with tonsil cancer
• The most recent figures estimate that 25.6% of all
oropharyngeal cancers are attributable to HPV
infection with HPV16 being the most frequent type
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano
R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV
Information Centre). Human Papillomavirus and Related Diseases in India. Summary Report 2015-
03- 20. [Accessed on 1st July 2015]
20. HEAD AND NECK CANCERS
Indicator MALE FEMALE
India World India World
Annual number
of new cancer
cases
31,735 115,131 6,956 27,256
Annual number
of deaths
27,002 77,585 5,782 18,505
Incidence and mortality of cancer of the pharynx (excluding nasopharynx) by sex in
India, and the World (estimations for 2012).
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M,
Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and
Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in India.
Summary Report 2015-03- 20. [Accessed on 1st July 2015]
21. ANAL CANCER
• Rare in general population
• Globally, there are an estimated 27,000 new cases every
year
• Women have higher incidences of anal cancer than men.
• Anal cancer is similar to cervical cancer with respect to
overall HPV DNA positivity, with approximately 88% of cases
associated with HPV infection worldwide
• HPV16 is the most common detected type, representing 73%
of all HPV-positive tumors
• HPV18 is the second most common type detected and is
found in approximately 5% of cases
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de
Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and
Related Diseases in India. Summary Report 2015-03- 20. [Accessed on 1st July 2015]
23. 1. *Ray K et al, Indian J Med Res 2006; 124: 559-56 - done in STD clinic; 2. Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M,
Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX, de Sanjosé S, Castellsagué X. ICO
Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in
India. Summary Report 2015-12-23. [Accessed on 2016-04-20 from http://hpvcentre.net/statistics/reports/IND.pdf
18.1%
5.8%
11% 10.5%
0
2
4
6
8
10
12
14
16
18
20
1990-93 1994-97 1998-01 2002-04
Study Period
Percentage
Genital Warts – Disease Burden: India*
THERE IS AN INCREASING TREND OF
GENITAL WARTS INCIDENCE IN INDIA
In approximately
10 years time the
incidence of GW
have increased 3
times1
HPV types 6 and
11 are responsible
for over 90% of all
anogenital warts2
24. Diagnosis of GW was strongly related to Anal, Vulvar,
Vaginal, Cervical and Head & Neck cancer with
confirmed HPV association
Standardized Incidence Ratios (SIRs) of Cancer among women (n = 33,422) diagnosed of GW in Denmark during 1978–2009
StandardizedIncidence
Ratios(SIRs)
2.8
1.5
5.9
7.8
14.8
4.7 4.8
0
2
4
6
8
10
12
14
16
All HPV
related
cancers
Cervix
uteri
Vagina Anus Vulva Tonsils HPV
Associate
d HNC
CI: 2.4- 3.1 CI: 5.5- 9.2 CI: 2.2-12.9 CI: 5.4- 11.0 CI: 11.7-18.6 CI: 2.3-8.4 CI: 2.7-8.0
Blomberg, Friis, Munk et al, Genital Warts and Risk of Cancer: A Danish Study of Nearly 50 000 Patients With Genital Warts, JID, 2012
25. SUMMARY
• HPV infection is a necessary cause of cervical cancer
and is linked to several other anogenital diseases
• There is an increasing body of evidence strongly
linking HPV DNA with cancers of anus, vulva,
vagina, and penis.
• Diagnosis of GW is strongly related to anal, vulvar,
vaginal, cervical & sub sites of Head & Neck cancer
with confirmed HPV association.
26. ISO 14001:2004 (EMS)
…..Caring hearts, healing hands
ISO 9001:2008
HELPLINE-
9650588339/22414049
HELPLINE-9599044257
HELPLINE-9910081484
ISO 9001:2008
HELPLINE
9599044357
![HPV RELATED DISEASES
• Human papillomavirus (HPV) infection is now a
well-established cause of cervical cancer. HPV
causes virtually 100% of cervical cancer cases
• There is growing evidence of HPV being a relevant
factor in other ANOGENITAL CANCERS (anus, vulva,
vagina and penis) and head and neck cancers.
• HPV is also responsible for other diseases such as
recurrent juvenile respiratory papillomatosis and
genital warts
Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz
J, Bosch FX, de Sanjosé S, Castellsagué X. ICO Information Centre on HPV and Cancer (HPV Information Centre).
Human Papillomavirus and Related Diseases in India. Summary Report 2015-12-23. [Accessed on 2016-04-20
from http://hpvcentre.net/statistics/reports/IND.pdf]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)