Biology is the branch of science which deals with the study of living organism and their life processes. It covers all aspect of the study of living creatures like growth, structure, occurrence, classification, ecology, economics importance, external form, organization, internal structure, nutrition among others
Biology is the branch of science which deals with the study of living organism and their life processes. It covers all aspect of the study of living creatures like growth, structure, occurrence, classification, ecology, economics importance, external form, organization, internal structure, nutrition among others
I can't claim credit for this presentation's original format; which a colleague downloaded. I've just added and tweaked a little so that it fits within my class's syllabus.
This ppt is based on Chapter 2 of the Grade-8 NCERT Science textbook. I have made it like a revision ppt which you can use to revise the concepts taught in the chapter
This is the second of a two part lesson on the scientific method. The earlier lesson was all about variables and this one focuses more on the procedures of the scientific method, at about the 5th and 6th grade level.
I can't claim credit for this presentation's original format; which a colleague downloaded. I've just added and tweaked a little so that it fits within my class's syllabus.
This ppt is based on Chapter 2 of the Grade-8 NCERT Science textbook. I have made it like a revision ppt which you can use to revise the concepts taught in the chapter
This is the second of a two part lesson on the scientific method. The earlier lesson was all about variables and this one focuses more on the procedures of the scientific method, at about the 5th and 6th grade level.
ICSE Class IX Biology Introducing Biology- TopperLearningAlok Singh
Science is an organised body of knowledge, supported by observation and experimentation, derived from the study of natural phenomena of the entire material universe
Biology, often referred to as the science of life, is a multifaceted field that delves into the study of living organisms, their interactions, and the intricate processes that sustain life.
Simply put, the living world can be described as the world around us. It comprises all living creatures, plants and microorganisms that we cannot see. It has changed over the course of billions of years but the general composition has remained the same. The main components are still organic and inorganic matter. Living things are divided into five kingdoms: animal, plant, fungi, protist and monera. Living things are divided into five kingdoms: animal, plant, fungi, protist and monera. Living things are divided into five kingdoms: animal, plant, fungi, protist and monera.
The life sciences comprise the fields of science that involve the scientific study of living organisms – such as microorganisms, plants, animals, and human beings – as well as related considerations like bioethics. While biology remains the centerpiece of the life sciences, technological advances in molecular biology and biotechnology have led to a burgeoning of specializations and interdisciplinary fields.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
2. Science ( from the Latin word scientia,
meaning “Knowledge”)
is a systematic enterprise that builds and
organize knowledge in the form of testable
explanations and predictions about the
universe.
Or, science is an organize form of knowledge
(through a process)
3. The word Biology is the combination of two
Greek words (bios- life, logos-study)
Biology is the branch of science which deals
with the study of living objects and their life
process.
(growth, structure, occurrence, classification,
ecology etc0
4. Term Biology was originated by Jean-Baptiste
Lamarck
Aristotle is known as the father of “Biology”
5. Botany – is the branch of biology which deals with the
scientific study of different aspects of plants and plant
like organisms which include algae, fungi, lichens,
mosses, ferns, conifers and flowering plant.
The ancient Greek Theophrastus is known as the
“Father/founder of Botany.
6. Deals with the scientific study of all living
organisms that are too small to see with the
naked eye.
Bacteria, viruses, fungi, protozoa and algae.
Antonie Philip van Leeuwenhoek is known as the “Father
of Microbiology”
7. Anatomy is a branch of biological science which is
concerned with the description of body structures of
various living organisms as revealed by dissection.
The word anatomy is derived from the Greek word
“anatomē”, where “ana” means “up” and “tome” means
“cutting.” Originally, anatomy was first learnt by cutting
up corpses, hence the name “anatomy.”
8. Genetics is termed as the study to understand the
functioning of inheritance of traits from parents to
offspring. The groundwork on which heredity
stands is known as inheritance. It is defined as the
procedure by which characteristics are handed
down from one generation to the other. Gregor
Johann Mendel is known as the “Father of Modern
Genetics” for his discoveries on the basic principles
of heredity.
9. Immunology is a branch of biology involved
with the study of the immune system,
components of the immune system, its
biological processes, the physiological
functioning of the immune system, types, its
disorders and a lot more.
10. Physiology is the study of the characteristics
and mechanisms of the human body.
11. Biotechnology is the use of technology for modifying or
manipulating a biological system for the benefits of human
beings. Biotechnology utilises a living system for making
different products.
Biotechnology is widely used in several fields such as agriculture,
medicine, genetics and the production of various commercial
products such as alcohol, wine, chemicals, etc. People have been
using biotechnology for ages for brewing and baking purposes.
12. The study of the relationships between
organisms and their environment, and the
balances between these relationship
13. Zoology is the branch of biology concerned with the
study animals and animal kingdom. It is also known as
animal biology. The study of zoology includes the
interaction of animal kingdom in their ecosystems such
as classification, habits, structure, embryology,
distribution, evolution, and extinct species.
