The circulatory system transports oxygen, nutrients, hormones and removes waste through a network of tubes called arteries, veins, lymph and capillaries. Blood is composed of plasma and cellular components like red blood cells, white blood cells and platelets. The circulatory system exchanges oxygen, food and carbon dioxide between blood in the capillaries and tissues through diffusion and hydrostatic pressure gradients across the capillary walls.
What is blood..
Its composition??
Plasma
Blood Cells (RBC, WBC, Platelets)
Its types
Its functions
FACTS AND FIGURES
Disorders of blood
Sequential Arrangement
Function of blood
Disorders of blood??
What is blood..
Its composition??
Plasma
Blood Cells (RBC, WBC, Platelets)
Its types
Its functions
FACTS AND FIGURES
Disorders of blood
Sequential Arrangement
Function of blood
Disorders of blood??
All living things are made up of cells.
Cells are the smallest working units of all living things.
All cells come from preexisting cells through cell division.
Body fluids are liquids originating from inside the bodies of living humans. They include fluids that are excreted or secreted from the body. Human blood, body fluids, and other body tissues are widely recognised as vehicles for the transmission of human disease.
Karl Landsteiner (June 14, 1868 – June 26, 1943).
Austrian biologist, physician, and immunologist.
Father of Transfusion Medicine .
In 1900 ,Karl Landsteiner found out that the blood of two people under contact agglutinates.
In 1901 ,he found that this effect was due to contact of blood with blood serum.
As a result, he succeeded in identifying the three blood group A,B,and O, which he labelled as C, of human blood.
Landsteiner also found out that blood transfusion between persons with the same blood group did not lead to the destruction of blood cells, whereas this occurred between persons of different blood groups
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Blood its functions composition and Haemopoiesis.pptxBYeshwantRao
Blood is a vital fluid connective tissue in the body.
It delivers oxygen and nutrients to the organs and tissues while removing waste products.
Study of blood is called HAEMATOLOGY.
Blood makes up about 7% of the total body weight of an adult, with an average volume of about 5 liters in males and 4.5 liters in females.
Blood is constantly replenished through a process called Haematopoiesis, which occurs in the bone marrow.
The cell is the basic unit of life. All organisms are made up of cells (or in some cases, a single cell). Most cells are very small; most are invisible without using a microscope. Cells are covered by a cell membrane and come in many different shapes. The contents of a cell are called the protoplasm.
Tissues- types and functions, glands and membranes bhartisharma175
it consist of tissues their types, glands and membranes. it also consist of colorful images which will help the students to identify and differentiate the different types of tissues from one another. different types of glands and membranes are also explained with the help of images.
All living things are made up of cells.
Cells are the smallest working units of all living things.
All cells come from preexisting cells through cell division.
Body fluids are liquids originating from inside the bodies of living humans. They include fluids that are excreted or secreted from the body. Human blood, body fluids, and other body tissues are widely recognised as vehicles for the transmission of human disease.
Karl Landsteiner (June 14, 1868 – June 26, 1943).
Austrian biologist, physician, and immunologist.
Father of Transfusion Medicine .
In 1900 ,Karl Landsteiner found out that the blood of two people under contact agglutinates.
In 1901 ,he found that this effect was due to contact of blood with blood serum.
As a result, he succeeded in identifying the three blood group A,B,and O, which he labelled as C, of human blood.
Landsteiner also found out that blood transfusion between persons with the same blood group did not lead to the destruction of blood cells, whereas this occurred between persons of different blood groups
For More Medicine Free PPT - http://playnever.blogspot.com/
For Health benefits and medicine videos Subscribe youtube channel - https://www.youtube.com/playlist?list=PLKg-H-sMh9G01zEg4YpndngXODW2bq92w
Blood its functions composition and Haemopoiesis.pptxBYeshwantRao
Blood is a vital fluid connective tissue in the body.
It delivers oxygen and nutrients to the organs and tissues while removing waste products.
Study of blood is called HAEMATOLOGY.
Blood makes up about 7% of the total body weight of an adult, with an average volume of about 5 liters in males and 4.5 liters in females.
Blood is constantly replenished through a process called Haematopoiesis, which occurs in the bone marrow.
The cell is the basic unit of life. All organisms are made up of cells (or in some cases, a single cell). Most cells are very small; most are invisible without using a microscope. Cells are covered by a cell membrane and come in many different shapes. The contents of a cell are called the protoplasm.
Tissues- types and functions, glands and membranes bhartisharma175
it consist of tissues their types, glands and membranes. it also consist of colorful images which will help the students to identify and differentiate the different types of tissues from one another. different types of glands and membranes are also explained with the help of images.
The cellular components of blood are erythrocytes (red blood cells, or RBCs), leukocytes (white blood cells, or WBCs), and thrombocytes (platelets). By volume, the RBCs constitute about 45% of whole blood, the plasma about 54.3%, and white blood cells about 0.7%. Platelets make up less than 1%.
This presentation gives you the knowledge about the body fluids, blood components, the process of blood clotting, blood grouping. It is helpful to determine the knowledge of human blood.
1 GNM - Anatomy unit - 3 - blood by thirumurugan.pptxthiru murugan
By:M. Thiru murugan
Unit – III:
Composition and formation of blood
Functions of blood
Blood clotting, blood grouping and cross matching
Blood products and their use
Blood
It is a connective tissue and circulating fluid including plasma and blood cells.
Physical characteristics:
More viscous than water.
100.4 degree F temperature.
8% of total body weight.
Average blood volume in males is 5-6 liters and female 4-5 liters
Composition of blood
Blood is made up of two main components.
Plasma (55%)
Blood cells (45%)
Plasma:
Normally 55% of our blood is made up of plasma
Composed of approximately 90% water.
plasma is the liquid portion of the blood.
Composition of blood
Plasma can be divided into 6 components:
Inorganic ions or Mineral ion.
The plasma proteins
Organic nutrients
Nitrogenous waste products
Hormones
Gases
Composition of blood
Blood cells 3 types of blood cells are
Red blood cells (erythrocytes)
White blood cells (leucocytes)
Platelets (thrombocytes)
Red blood cells:
Also called erythrocytes & Biconcave shape
95% of the RBC consist of haemoglobin(red pigment)
Remaining 5% consist of enzymes, salts and other protein
Formed in red bone marrow
Average life span is 4 months (120 days)
Composition of blood
Function:
To transport oxygen & carbon dioxide.
Blood of male contains 5-5.5 million RBC per cubic millimetres.
Blood of female contains 4-4.5 million RBC per cubic millimetres
2) White blood cells: Also called as leucocytes
They are colourless & Much larger than red blood cells
One cubic millimetres of blood contains 7000 to 8000 WBC
Formed in bone marrow
Their life span depends on the body need so they have life span of months or even years
Composition of blood:
Types of WBC:
Granulocytes: neutrophils, eosinophils and basophils.
Agranulocytes: monocytes and lymphocytes.
Main function:
These are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
Composition of blood:
3) platelets: also called Thrombocytes.
Normal platelet count is 150,000-400,000/ drop of blood
Platelets have a life span of only 5 to 9 days
Platelets are formed in Bone marrow
Function:
Involving in blood coagulation (blood clotting)
Blood Formation
Hemopoiesis ( haematopoiesis) or hemopoiesis, is the process that produces the formed elements of the blood.
Hemopoiesis takes place in the bone marrow found in the epiphyses of long bones (for example, the humerus and femur), flat bones (ribs and cranial bones), vertebrae, and the pelvis.
Within the bone marrow, hemopoietic stem cells ( hemocytoblasts) divide to produce various “blast” cells.
Each of these cells matures and becomes a particular blood cells.
The rate of blood cell formation depending on the individual
But - average 200 billion RBC per day, 10 billion WBC per day, and 400 billion platelets per day
Blood Formation
Blood cells are made in the bone marrow & located inside some bones.
It contains young p
DETAILED CHAPTER OF BODY FLUIDS AND CIRCULATION.
WELL EXPLAINED WITH DIAGRAM. WELL ORGANISED POWER[POINT TEMPLATES. SHORT AND PRECISE NOTES. WELL DEFINED TOPICS FOR EACH SUBJECTS.
Body Fluids And Circulation Class 11thNehaRohtagi1
Created By: NehaRohtagi1
Class 11th CBSE [NCERT]
Biology Chapter 18
Notes on the topic: Body Fluids and Circulation
For Class - 11th
I hope that you will found this presentation useful and it will help you out for your concept understanding.
Thank You!
Please give feedbacks and suggestions to get presentations on more interesting topics.
Do not repost or copy.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. • circulatory system consists of the
circulatory medium and a system of
tubes.
• Circulatory medium: blood, lymph and
tissue fluid.
• System of tubes: arteries, veins, lymph
vessels and capillaries
3. Function of circulatory system:
transport oxygen and nutrients to different
body cells.
removes carbon dioxide and other waste
products from the body.
Carries hormones from their site of origin
to distant target tissues.
4.
5. BLOOD
• Blood is a fluid connective tissue.
• Plays an important role in the maintenance
and regulation of pH and body temperature.
• Protects our body from pathogens and
foreign substances.
• The average adult body has approximately
about 5 to 6 litres of blood.
8. Plasma
It is the yellow liquid part of the blood
The plasma from which the
protein fibrinogen has been
removed is called serum.
9.
10. A myth: Why do vampires drink blood?
Some vampires use blood as medication—an
iron-rich supplement to
combat blood conditions such as anemia.
For them, consuming blood is a quality of life
issue and is necessary for sustaining their
energy.
11. Class work
Q1. List down two functions of blood.
Q2. Blood is a fluid …………….tissue.
Q3. The blood is composed of about 55%
………… and ………% cellular components
Q4. Cellular components includes …….. ,
…………and ……………
Q5. ………is the yellow liquid part of the blood
Q6. The plasma from which the protein
fibrinogen has been removed is called …………
Q7. Mention any TWO functions of Plasma.
14. RBC/ Erythrocytes
• Size: 7-8 micron
• Shape: Biconcave disc shaped body with a
central depression
• Constitutes about 60% of the blood volume.
• The cell is without a nucleus or mitochondria
• Contain a red pigment called haemoglobin.
• Haemoglobin helps to transport oxygen and
carbon dioxide in blood
• Constitutes about 60% of the blood volume.
• Life span: 120 days and is destroyed in the
spleen
15. • The main function of RBCs is :
• Transportation of oxygen from the lungs to
tissues, and carbon dioxide from tissues to the
lungs.
Production of red blood cells
• produced in the bone marrow of the bones.
• controlled by a hormone called erythropoietin.
• No nucleus so that they can easily change
shape and fit through the various blood vessels
in the body.
RBC/ Erythrocytes
16. • The percentage of red blood cells volume
to the total blood volume is called
hematocrit.
• Normal blood count of RBC is 4.5 to 5.5 per
mL in adult human.
• The normal average is about 46% in male, and
42% in female.
• An increase in hematocrit is called
polycythemia
Hematocrit = % of RBCs
17. • Decrease in hematocrit is called anemia.
• If the blood count of RBC is less than the
normal value, then it is due to some deficiency
like low level of oxygen in blood cells,
deficiency in iron, vitamin B12, blood loss and
other infections.
18. Q8. The red pigment present in erythrocyte is
called………..
Q9. RBC is biconcave shape with no nucleus. Explain.
Q10. Life span of RBC is……., and is destroyed in
the………
Q11. What is the main function of RBCs?
Q12. RBC is produced in…………
Q13. the hormone that controls the production of RBC
is…………
Q14. How do you calculate hematocrit?
Q15. An increase in hematocrit is called ………..
and decrease in hematocrit is called ……….
19. WBCs/ Leukocytes
• Produced in the bone marrow of
the bones and lymph nodes
• irregular in shape with a nucleus
• Part of the immune system that destroys
infectious agents called pathogens
• Have ability to move in and out of the blood
vessels
• Size: 10-12 microns
• Life span: 12 hours to
12 days.
25. Identify the following:
1. Stain dark red with eosin.
2. Releases chemical histamine during inflammatory
reactions.
3. Protect against the blood borne pathogens.
4. The nucleus is generally of half -moon shaped or
kidney shaped
5. Nucleus is 3 to 5 lobed.
6. Produce antibodies to attack and destroy virus and
bacteria.
7. The process that destroy and digest virus and
bacteria by engulfing them in is called……………
26. Production of WBCs
• White blood cells are mostly produced in bone marrow
and few produced in lymph nodes and spleen.
• Produced more during the time of injury and
infections.
• Normal WBC counts: 6,000 to 9,000 per cubic mL of
blood.
• Overproduction of WBCs is caused due to inflammatory
disease like - anemia, leukemia
• Lesser production of WBC can be due to bone marrow
deficiency and exposure to radiations.
29. Blood platelets (Thrombocytes)
• Shape: small, oval or round structures, non-
nucleated.
• Size: 2 to 3 microns
• Lifespan: 3 to 5 days.
• The total count of platelets
is about 2,00,000 to
3,00,000 per mL of blood.
• Platelets are small fragments of giant cells
called megakaryocytes
• Production is controlled by a hormone called
thrombopoietin
30. Clotting of blood
• Platelets play vital role in blood clotting.
At the site of injury, they disintegrate and
release a chemical substance known as
thrombokinase, which initiates the process
of clotting.
• Platelets normally remain inactive in the
blood until they reach the damaged
tissue.
• Once activated, platelets change into a
spiny ball shape and become very sticky
and stick on to the damaged tissues.
31. • Heparin- a protein present in blood plasma
prevents the blood clotting during normal
condition.
• A condition in which blood fails to clot
is known as haemophilia.
32. What did you learn?
1. A giant cell called ………….... breaks into small
fragments to form blood platelets.
2. A condition in which blood fails to clot is
known as ………….
3. Production of platelet is controlled by a hormone
called ………………
4. A protein present in blood plasma prevents
the blood clotting during normal condition is………
5. Platelets do not have nucleus (T/F).
6. Blood platelets is also called as leukocyte (T/F)
36. Class Work
1. Cell fragments that formed from the rupture of a
megakaryocyte are called…………….
2. The ions responsible for the process of blood clot
is……………..
3. A plasma protein important for blood clotting
is………….
4. A condition in which blood fails to clot is
known as ………….
5. …………..is the chemical substance produced by
platelets at injury site.
6. Main function of platelets is……………….
7. Explain blood clotting in your own words.
37. ABO System
• Blood groups are classified into four major
blood groups determined by the presence or
absence of two antigens: A and B.
• Antigens are the protein on the surface of a
RBC membrane.
• The proteins produced by lymphocytes in
response to the presence of antigens is
called antibody. Antibody A and B.
• The main role of the antibody is to attack
foreign antigens.
• The four kinds of blood groups are A, B, AB
and O.
38.
39.
40.
41. Rh (Rhesus) factor
• Another group of antigens found on the
red blood cells
• People who have these antigens are said
to be Rh positive (Rh+), whereas those
who do not are Rh negative (Rh-).
• Rh- person can develop Rh+ antibodies
upon receiving blood from Rh+ person.
42. Blood Transfusion
• Blood transfusions are done through intravenous line
to replace blood lost during surgery or due to serious
injury/illness.
• Mixing unrelated blood from two individuals can lead
to blood clumping or agglutination. The clumped red
cells can crack and cause toxic reactions. This can
have fatal consequences.
43. Blood Types Explained - A, B, AB and O | Red Cross Blood Services
Rh+ person can receive blood from any other blood
type but a person with Rh- person can receive blood
from Rh– persons only.
46. Questions
1. Following a motor vehicle accident, a patient
is rushed to the emergency department with
multiple traumatic injuries, causing severe
bleeding. The patient’s condition is critical,
and there is no time for determining his blood
type. What type of blood is transfused, and
why?
2. A drop of blood from a blood donor is mixed
with serum from a group A person and serum
from a group B person. The donor's red cells
clumped in the A serum but not in the B
48. • Artery carry blood away from the heart and veins carry
blood towards the heart.
• Oxygen, food and carbon dioxide are exchanged between
the blood and the organ cells by diffusion.
• Tissue fluid is similar to plasma but its lacks proteins.
• Tissue fluid collects carbon dioxide and other excretory
substances.
• Fluid exchange is controlled by blood pressure within the
capillary vessel and osmotic pressure of the blood.
49. • The osmotic pressure is produced by high
concentrations of salts and plasma proteins
in the blood.
• The pressure exerted by fluids, such as blood
and tissue fluid, against the walls of the
capillaries is called hydrostatic pressure/blood
pressure.
• The source of the hydrostatic blood pressure is
the pumping action of the heart.
50.
51.
52. Revision questions
1)……………..is the pressure exerted by fluid in an
enclosed space against the capillaries wall.
3) The plasma proteins suspended in blood cross
the capillary cell membrane and enter the tissue
fluid via diffusion. True or False? Explain your
thinking.