The document summarizes key concepts about blood, including: 1. Blood is composed of plasma, red blood cells, white blood cells, and platelets. Red blood cells carry oxygen, while white blood cells help fight infection. 2. The production and lifespan of red blood cells is described, along with the different types of white blood cells. Hemostasis and blood clotting are explained briefly. 3. Blood typing is discussed, including the ABO and Rh blood group systems. Compatibility for blood transfusions depends on the presence or absence of antigens on red blood cells.

1. Chapter 14 Blood PowerPoint Presentation to accompany Hole’s Human Anatomy and Physiology, 10 th edition , edited by S.C. Wache for Biol2064.01

2. You are responsible for the content of the following figures and topics: Fig. 14.1 – Blood. Fig. 14.2 - hematocrit or Percent packed RBC volume. Fig. 14.5 - Blood originates from red bone marrow. Fig. 14.3 - Blood cells. WBC develop into 3 branches. Fig. 14.14 - WBC can pass through the simple epithelia of vessels by diapedesis, RBC cannot. Fig. 14.16 - Blood composition. Read TB, p.527, on hemostasis. Fig. 14. 19, Tab. 14.10 - Damaged tissues trigger the extrinsic mechanism. Read TB, p.533, on antigens and antibodies of blood groups. Fig. 14.21, 14.22 – Key-and-Lock interaction of Antigens and Antibodies. Tab. 14.13 - Study the antibodies each blood type carries in their plasma. Tab. 14.14 - Permissible Donor Blood Types. Fig. 14.23 - incompatibility with the Rh antigen also called antigen D.

4. Fig. 14.3

6. Fig. 14.8 Note that, in muscle, myoglobin (Mb) binds oxygen. Mb consists of only 1 protein chain. Note the 4 protein chains that make up 1 molecule of Hb.

8. Fig. 14.6

9. Fig. 14.7 NORMAL BLOOD ANEMIC BLOOD ane·mia : a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume – see APLASTIC ANEMIA, HYPERCHROMIC ANEMIA, HYPOCHROMIC ANEMIA, MEGALOBLASTIC ANEMIA, MICROCYTIC ANEMIA, PERNICIOUS ANEMIA, SICKLE-CELL ANEMIA; compare OLIGOCYTHEMIA

19. Infection

21. Fig. 14.16

23. Fig. 14.17

24. Fig. 14.19

28. Fig. 14.22 Donor RBCs: They carry the antigen A. The donor is Blood Type A. Patient Blood: The patient is blood type B and has naturally occurring antibodies called Anti-A. Patient blood after wrong transfusion: The patient blood agglutinates and hemolyses. The patient dies.

29. Fig. 14.21