Leukemia is a cancer of the blood characterized by an abnormal increase in white blood cells. There are four main types of leukemia - acute lymphoblastic leukemia, acute myelogenous leukemia, chronic lymphoblastic leukemia, and chronic myelogenous leukemia. Risk factors include radiation, viruses, chemicals like benzene, and genetic predispositions. Symptoms can include fatigue, fever, frequent infections, and easy bleeding. Diagnosis involves blood tests, bone marrow biopsy, and other scans. Treatment may include chemotherapy, radiation therapy, stem cell transplants, and monoclonal antibodies depending on the type of leukemia.

1. LEUKEMIA
Presented By: B.PHARM 1ST YEAR 2ND SEMESTER
Name: Mainak Ghosh, Lopamudra saha, Kuntal Mondal
Roll No: 18601917094,18601917095,18601917096
Registration
No:171860210045,171860210044,171860210043
Session: 2017-2021
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A PROJECT ON

2. LEUKEMIA
 Definition of Leukemia
an acute or chronic disease in humans and other
warm-blooded animals characterized by an
abnormal increase in the number of white blood
cells in the tissues and often in the blood .
 Normal WBC count of a person is 4500-11000/ml
blood.
 For leukemic patient theWBC count is 50000-
100000/ml blood
 Leukemia cells can spread to lymph nodes &spleen
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3. General TYPES OF LEUKEMIA
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ACUTE CHRONIC LYMPHOID MYELOID
Rapid growth of
immature blood
cells
Excessive build
up of mature
blood cells
Affects
lymphocytes and
plasma cells
Affects
Eosinophil,Neutr
ophil, Basophil
Mostly occur in
children and
young adults and
require
immidiate
treatment
Mostly occur in
older patients,
and monitoring
before
treatment
Also known as
Lymphocytic
Leukemia
Also known as
Myolegenous
Leukemia.

4. 4 common types of Leukemia
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Acute
Lymphoblastic
Leukemia
Acute
Myelogenous
Leukemia
Chronic
lymphoblastic
Leukemia
Chronic
Myelogenous
Leukemia
Found in
lymphoid cells
grow quickly
common in
children 6,000
cases a year
Found in myeloid
cells grows
quickly common
in adults and
children 18,000
cases a year
Found in
lymphoid cells
grows slowly
common in
adults 55+ 15,000
cases a year
Found in myeloid
cells grows
slowly common
in adults 6,000
cases a year

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6. Causes of Leukemia
 1.Leukemia happens when DNA of immatureWBC are damaged, this
causes blood cell to grow and divide continuously .
 Risk factors
 artificial ionizing radiation
 viruses, such as the humanT-lymphotropic virus (HTLV-1) and HIV
 benzene and some petrochemicals
 alkylating chemotherapy agents used in previous cancers
 hair dyes
 Smoking
 People have Down Syndrome more risk to develop Leukaemia due
to some chromosomal changes..
 Genetic predisposition: Some people appear to have a higher risk of
developing leukemia because of a fault in one or several genes.
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7. Symtoms of Leukemia
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8. Diagonosis For Leukemia
 Diagonostic test:
 Complete blood count (CBC)
 Blood chemistry tests
 Bleeding and clotting factors
 Cytochemistry
 ImmunophenotypingBone marrow aspiration and biopsy
 Lymph node biopsy
 Blood chemistry tests
 Chest x-ray
 CT scan
 MRI
 Ultrasound 8

9. Treatments For Leukemia
Chemotherapy is the standard treatment for many types
of leukemia. Chemotherapy is usally combination of drugs.
except chemotherapy drugs, other medicine can given to
work better the chemotherapic drugs and prevent bleeding.
These days include epotein and hematopoetic
Acute lymphoblastic leukemia, chemotherapy medicine are
V Incristine, Doxorubicin and Corticoseriods are used
Mitoxantnine used for Acute Myelogenous Leukemia and
Fludarabine monoclonal antibodies is treat for chornic
Lymphocytic Leukemia
Except chemotherapy Radiation therapy, stem cell
transplant also used to treat Leukemia.
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CONCLUSION
Leukemia occuer 10.2% of total cancer in recent
centuries. According to NCI’S report 6.7% woman
suffer in leukemia and 10.7% man suffer in Leukemia.
To prevent this we should check up our health
daily.

11. REFFERENCES
 ColvinG. A.; Elfenbein G. J. (2003). "The latest treatment advances
for acute myelogenous leukemia". Medicine and Health, Rhode Island
, page 24–76.
 ElaineSarkinJaffe, Nancy Lee Harris,World Health Organization,
International Agency for Research on Cancer, Harald Stein,J.W.
Vardiman , page 21-60
 Hutter, JJ (Jun 2010),"Childhood leukemia",page 8-16
 World Cancer Report 2014,World Health Organization,2014,Chapter
5.13.
 Reiter A, Gotlib J (2017). "Myeloid neoplasms with eosinophilia".
Blood. 129 (6): 694–714.
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