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Biomolecules
Sreesaila N P
Assistant Professor
Department of Biotechnology
St. Mary’s College Thrissur
BIOMOLECULES
 Chemicals or molecules present in living organisms
 Biomolecules are compounds of carbon with a variety of functional
groups.
 Chemicals of living organisms organized around carbon
 Carbon bonds with hydrogen, oxygen, nitrogen, etc.,
 Cellular pool – different biomolecules, compounds, ions
Biomolecules, Sreesaila N P, St Mary’s college
Carbon bonding
 Free rotation around each single bond.
 Rotation restricted to large/highly charged groups
 Double bond is shorter and rigid
 Covalently linked carbon atoms can form linear, branched chain or
cyclic structures in biomolecules.
 Bonding versatility - molecular mechanism during origin and evolution
 No other chemical element can form such varieties of compounds like
CARBON.
Most biomolecules are derivatives of hydrocarbons
Biomolecules, Sreesaila N P, St Mary’s college
Types of BIOMOLECULES
 Micro molecules
• 18 – 800 dalton
•Acid soluble
•Minerals, gases, water, sugars, amino acids.
 Macromolecules
•10000 dalton
•Acid insoluble pool
•Carbohydrates, nucleic acids, lipids, proteins
Biomolecules, Sreesaila N P, St Mary’s college
Types of BIOMOLECULES
 Inorganic :
• Minerals
• Water
• Gases
 Organic :
• Carbohydrates
• Nucleic acids
• Proteins
• Amino acids
• Lipids
• Enzymes
• Vitamins
Biomolecules, Sreesaila N P, St Mary’s college
 Biomolecules are made up of
sub units
 Each are having their own
characteristics and structures
 Eg: Protein is made up of
amino acid sub units.
 Protein functions as enzymes,
structure, transport pigment
etc.,
Biomolecules, Sreesaila N P, St Mary’s college
Carbohydrates
 C, H, O ratio 1:2:1
 Monosaccharide,
disaccharide, oligosaccharide
and poly saccharide.
 Energy source.
 Brain functioning
Biomolecules, Sreesaila N P, St Mary’s college
Structure of CARBOHYDRATES
Biomolecules, Sreesaila N P, St Mary’s college
DERIVATIVES OF MONOSACCHARIDES
• 1. Deoxy sugars – DNA
• 2. Amino sugars – Glucosamine( forms chitin, hyaluronic acid)
• 3. Sugar acid – Ascorbic acid
• 4. Sugar alcohols – Glycerol, Mannitol
Biomolecules, Sreesaila N P, St Mary’s college
Structural forms of CARBOHYDRATE
Monosaccharides – monomer of carbohydrates
Eg; GLUCOSE
Disaccharides – two monosaccharides
Eg; MALTOSE ( GLUCOSE + GLUCOSE)
Polysaccharides – many monomers
Eg; STARCH, GLYCOGEN, CELLULOSE
(energy storage form in plants, in animals and plant cell wall
component respectively)
Biomolecules, Sreesaila N P, St Mary’s college
Cells use them for energy and growth.
Make up the walls of the plant cell (glycoprotein and glycolipids).
Animals store the glucose to glycogen.
Animals store glycogen in liver cells.
Exoskeleton of some insects
Endergonic reactions.
Precursers of many organic compounds
Uses of CARBOHYDRATES
Biomolecules, Sreesaila N P, St Mary’s college
REFERENCE
1. Lehninger’s Principles of biochemistry, sixth edition, 2009.
2. “ The Role of carbohydrates in nutrition” Carbohydrates in
human nutrition. FAO food and nutrition paper-66. Food
and agriculture organization of the United states
Biomolecules, Sreesaila N P, St Mary’s college

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Biotechnology:Biomolecules

  • 1. Biomolecules Sreesaila N P Assistant Professor Department of Biotechnology St. Mary’s College Thrissur
  • 2. BIOMOLECULES  Chemicals or molecules present in living organisms  Biomolecules are compounds of carbon with a variety of functional groups.  Chemicals of living organisms organized around carbon  Carbon bonds with hydrogen, oxygen, nitrogen, etc.,  Cellular pool – different biomolecules, compounds, ions Biomolecules, Sreesaila N P, St Mary’s college
  • 3. Carbon bonding  Free rotation around each single bond.  Rotation restricted to large/highly charged groups  Double bond is shorter and rigid  Covalently linked carbon atoms can form linear, branched chain or cyclic structures in biomolecules.  Bonding versatility - molecular mechanism during origin and evolution  No other chemical element can form such varieties of compounds like CARBON. Most biomolecules are derivatives of hydrocarbons Biomolecules, Sreesaila N P, St Mary’s college
  • 4. Types of BIOMOLECULES  Micro molecules • 18 – 800 dalton •Acid soluble •Minerals, gases, water, sugars, amino acids.  Macromolecules •10000 dalton •Acid insoluble pool •Carbohydrates, nucleic acids, lipids, proteins Biomolecules, Sreesaila N P, St Mary’s college
  • 5. Types of BIOMOLECULES  Inorganic : • Minerals • Water • Gases  Organic : • Carbohydrates • Nucleic acids • Proteins • Amino acids • Lipids • Enzymes • Vitamins Biomolecules, Sreesaila N P, St Mary’s college
  • 6.  Biomolecules are made up of sub units  Each are having their own characteristics and structures  Eg: Protein is made up of amino acid sub units.  Protein functions as enzymes, structure, transport pigment etc., Biomolecules, Sreesaila N P, St Mary’s college
  • 7. Carbohydrates  C, H, O ratio 1:2:1  Monosaccharide, disaccharide, oligosaccharide and poly saccharide.  Energy source.  Brain functioning Biomolecules, Sreesaila N P, St Mary’s college
  • 8. Structure of CARBOHYDRATES Biomolecules, Sreesaila N P, St Mary’s college
  • 9. DERIVATIVES OF MONOSACCHARIDES • 1. Deoxy sugars – DNA • 2. Amino sugars – Glucosamine( forms chitin, hyaluronic acid) • 3. Sugar acid – Ascorbic acid • 4. Sugar alcohols – Glycerol, Mannitol Biomolecules, Sreesaila N P, St Mary’s college
  • 10. Structural forms of CARBOHYDRATE Monosaccharides – monomer of carbohydrates Eg; GLUCOSE Disaccharides – two monosaccharides Eg; MALTOSE ( GLUCOSE + GLUCOSE) Polysaccharides – many monomers Eg; STARCH, GLYCOGEN, CELLULOSE (energy storage form in plants, in animals and plant cell wall component respectively) Biomolecules, Sreesaila N P, St Mary’s college
  • 11. Cells use them for energy and growth. Make up the walls of the plant cell (glycoprotein and glycolipids). Animals store the glucose to glycogen. Animals store glycogen in liver cells. Exoskeleton of some insects Endergonic reactions. Precursers of many organic compounds Uses of CARBOHYDRATES Biomolecules, Sreesaila N P, St Mary’s college
  • 12. REFERENCE 1. Lehninger’s Principles of biochemistry, sixth edition, 2009. 2. “ The Role of carbohydrates in nutrition” Carbohydrates in human nutrition. FAO food and nutrition paper-66. Food and agriculture organization of the United states Biomolecules, Sreesaila N P, St Mary’s college