This document discusses two-phase flow line sizing for liquid-gas flows in piping systems. It describes the different flow regimes that can occur using Baker's flow regime map. The key steps outlined are: 1) determining the flow regime based on fluid properties and flow rates, 2) calculating pressure drops for the liquid and gas phases separately using correlations, 3) using a multiplier to determine the two-phase pressure drop based on the flow regime, and 4) summing pressure drops from friction, elevation changes, and fittings to obtain the total pressure drop. Care must be taken to size each pipe segment separately as properties and regimes can change along the line.