- The document discusses parametric and non-parametric data, describing key differences. Non-parametric data is for small samples and variables that are not normally distributed, requiring no assumptions. Descriptive statistics include range, rank, median, and interquartile range.
- It also covers topics like mean, standard deviation, standard error, confidence intervals, and the normal and t-distributions as they relate to parametric statistical analysis of sample and population data. The central limit theorem is also referenced.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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General statistics, emphasis of statistics with regards to healthcare, types of stats, methods of sampling, errors in sampling, different types of tests, measures of dispersion, correlation, types of correlation
This powerpoint presentation gives a brief explanation about the biostatic data .this is quite helpful to individuals to understand the basic research methodology terminologys
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
General statistics, emphasis of statistics with regards to healthcare, types of stats, methods of sampling, errors in sampling, different types of tests, measures of dispersion, correlation, types of correlation
This powerpoint presentation gives a brief explanation about the biostatic data .this is quite helpful to individuals to understand the basic research methodology terminologys
Lecture of Respected Sir Dr. L.M. BEHERA from N.I.H. KOLKATA in a workshop at G.D.M.H.M.C. - Patna in the Year 2011.
SUBJECT : BIOSTATISTICS
TOPIC : 'INTRODUCTION TO BIOSTATISTICS'.
This slide explains term biostatistics, important terms used in the field of bio statistics and important applications of biostatistics in the field of agriculture, physiology, ecology, genetics, molecular biology, taxonomy, etc.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
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4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) ...Tin Myo Han
Showing relationship between Epidemiology, Bio-statistics and Dental public health activities for 4th year dental students
to get more understanding on why they need to do students' research project and how to apply it!
Lecture of Respected Sir Dr. L.M. BEHERA from N.I.H. KOLKATA in a workshop at G.D.M.H.M.C. - Patna in the Year 2011.
SUBJECT : BIOSTATISTICS
TOPIC : 'INTRODUCTION TO BIOSTATISTICS'.
This slide explains term biostatistics, important terms used in the field of bio statistics and important applications of biostatistics in the field of agriculture, physiology, ecology, genetics, molecular biology, taxonomy, etc.
Bhaskar Health News and Medical Education is leading source for trustworthy health, medical, science and technology news and information. Providing world health information Medical Education.
Bhaskar Health News and Medical Education is dedicated to medical students, physiotherapists, doctors, nurses, paramedics, physician associates, dentists, pharmacists, midwives and other healthcare professionals.
We're committed to being your source for expert health guidance. Bhaskar Health and Medical Education.
Source : https://www.bhaskarhealth.com
Health Shop: https://www.bhaskarhealth.org
@drrohitbhaskar @bhaskarhealth
#DrRohitBhaskar #BhaskarHealth
#Health #Medical #News #Physiotherapy
4.epidemiology tutorial (realtioonship of epidemiology biostatistics & dph ) ...Tin Myo Han
Showing relationship between Epidemiology, Bio-statistics and Dental public health activities for 4th year dental students
to get more understanding on why they need to do students' research project and how to apply it!
Module 3: Oral Health Data Tools and StatisticsKelley Minars
The updated version of this tutorial can be found here: http://www.slideshare.net/uthsclib/module-3-oral-health-data-tools-and-statistics-1724970
Module 3 of the Oral Health Tutorial, a production of UT HSC Libraries.
This module focuses on data tools and statistics. View this tutorial to develop a basic understanding of the types of statistics and data sets that are available related to oral health and to identify health related web sources with statistics.
This tutorial is copyright Lara Sapp and Julie Gaines. Uploaded with permission.
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Exploratory Data Analysis for Biotechnology and Pharmaceutical SciencesParag Shah
This presentation will give perfect understanding of data, data types, level of measurements, exploratory data analysis and more importantly, when to use which type of summary statistics and graphs
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Basics in Epidemiology & Biostatistics 2 RSS6 2014
1. Basics in Epidemiology & Biostatistics
Hashem Alhashemi MD, MPH, FRCPC
Assistant Professor, KSAU-HS
2. • Large samples > 30.
• Normally distributed.
• Descriptive statistics:
Range, Mean, SD.
Non-parametric data
• For small samples & variables
that are not normally
distributed.
• No basic assumptions
(distribution free).
• Descriptive statistics:
Range, Rank, Median, & the
interquartile range.
(the middle 50 = Q3-Q1).
• Median is the middle number
in a ranked list of numbers
(regardless of its frequency).
Parametric data
4. The Mean
• It sums all the values (great digital summary ).
• But, it will be affected by extreme values. So, it is not
a good summary if your data is not normal
(symmetrical bell shape).
• The sum of data differences above and below the
mean will equal = 0.
"الوسط األمور خير شطط التناهي حب"
5. Stander Deviation
Average of differences from the mean (Squared-SS)
Sample set:
1 ,2 ,3 ,4 , 5 ,6 ,7
X = 28/7= 4
Number of differences = 6
(n-1)
Stander deviation
Unit of deviation of data from the Mean
8. • Zdistribution, is a hypothetical population
(model) with a 𝛍 of 0, & 𝛔 1.
• Six (𝛔 ) make up 0.997 of the area under the
curve
Z distribution
Parametric
Data
Population
%
9. • God knows every thing.
• Dose not need to take samples.
• Commits no mistakes.
10. Central Limit Theorem
• The mean of all possible sample means will be
approximately equal to the mean of the
population.
• The distribution of all possible sample means
will be normal.
• If you limit your prediction to the center, you
will be ok (averages are normally distributed)
(1777 – 1855)
"الوسط األمور خير شطط التناهي حب"
Carl Friedrich
Gauss
11. • tdistribution, is a hypothetical population (model)
with a 𝛍 of 0, & 𝛔 1 , (Degrees of freedom= n-1).
• Six (𝛔 ) make up 0.997 of the area under the curve
t distribution
Parametric
Data
Sample
Sampling distribution
%
13. Stander Error
SE is the unit for error in estimating the population mean.
SE is the unit for deviation of all possible samples means from the
population mean.
SE is the unit for average difference of all possible samples means
from population mean.
n because S is a root product of the variance.
14. The Average Idea
SE Stander ErrorS Stander DeviationX mean
A unit for Error in
estimation of the
population mean.
A unit of Deviation of the
data from the sample
mean.
Average
A unit for Deviation of
all possible samples
means from the
population mean.
A unit for Average of
differences of the data
from the sample mean.
A unit for Average of
differences of all
possible samples means
from population mean.
17. 95% Confidence Interval (C.I)
SE
Stander of
Error
+/- 2 SE
μ
π
Ω
λ
Estimate Margin of Error
X
P
OR
Rate
General formula
18. SD vs SE
• Standard Deviation calculates the variability of the
data within a sample in relation to the sample mean .
• Standard Error estimates the variability of all possible
samples means in relation to the population mean.
So, it helps identify the % of data above and below a
certain measurement.
So, it helps identify the degree of error in your
estimation.
22. • Large samples > 30.
• Normally distributed.
• Descriptive statistics:
Range, Mean, SD.
Non-parametric data
• For small samples & variables
that are not normally
distributed.
• No basic assumptions
(distribution free).
• Descriptive statistics:
Range, Rank, Median, & the
interquartile range.
(the middle 50 = Q3-Q1).
• Median is the middle number
in a ranked list of numbers.
Parametric data
23. Non-parametric data
• For small samples and variables that are not
normally distributed.
• No basic assumptions (distribution free).
• Descriptive statistics: Range, Rank, Median, and
the interquartile range (the middle 50 = Q3-Q1).
25. Non-parametric data
• For small samples and variables that are not
normally distributed.
• No basic assumptions (distribution free).
• Descriptive statistics: Range, Rank, Median, and
the interquartile range (the middle 50 = Q3-Q1).
33. Approximation to Normality
• If choices are equally likely to happen
• If repeated numerous number of times
• It will look normal.
• Whether it was a coin or a dice
(Di-chotomous or Multi-chotomous)
35. Choices equally likely to happen…..
i.e. Out come of interest probability is unknown
(Research ethics)
Repeated numerous number of times….
i.e. Large sample size
Normality assumption helps us predict
the Probability of our outcome
36. The Bell / Normal curve
Stander deviation(SD)/ sample curve
True error (SE)/ population curve
• Was first discovered by Abraham de Moivre in 1733.
• The one who was able to reproduce it and identified
it as the normal distribution (error curve) was Gauss
in 1809.
37. De Moivre had hoped for a chair of
mathematics, but foreigners were at a
disadvantage, so although he was free
from religious discrimination, he still
suffered discrimination as a Frenchman in
England.
Born 1667 in Champagne, France
Died 1754 in London, England