The word Archae came from the Greek word Arkhaion, which means “Ancient”.
Archae is also the Latin name for Prokaryotic Cells. Archaea that growing the hot water of the Hot Spring in Yellowstone National Park produce a bright yellow color.
Archaebacteria are known to be the oldest living organisms on earth. They belong to the kingdom Monera and are classified as bacteria because they resemble bacteria when observed under a microscope. Apart from this, they are completely distinct from prokaryotes. However, they share slightly common characteristics with the eukaryotes.
Major divisions in Bergey's manual of systematic bacteriology 2nd edition presented for examination purpose. Pinned important points are compiled here for students.
The word Archae came from the Greek word Arkhaion, which means “Ancient”.
Archae is also the Latin name for Prokaryotic Cells. Archaea that growing the hot water of the Hot Spring in Yellowstone National Park produce a bright yellow color.
Archaebacteria are known to be the oldest living organisms on earth. They belong to the kingdom Monera and are classified as bacteria because they resemble bacteria when observed under a microscope. Apart from this, they are completely distinct from prokaryotes. However, they share slightly common characteristics with the eukaryotes.
Major divisions in Bergey's manual of systematic bacteriology 2nd edition presented for examination purpose. Pinned important points are compiled here for students.
Bergey's Manual and it's classification. A brief concised presentation prepared for taking seminar and classes.
Volume II (Edition 2) described more in detail.
Archaebacteria are the oldest organisms living on the Earth. They are
unicellular prokaryotes and belong to the kingdom, Archaea. They were first
discovered in 1977 and classified as bacteria. Most archaebacteria appear like
bacteria, when observed under the microscope. However, they are quite
different from bacteria and eukaryotic organisms.
Archaebacteria are found in very harsh conditions such as in the volcanic vents
or at the bottom of the sea. They can easily survive in such extreme
environment as sea vents releasing sulfide-rich gases, hot springs, or boiling
mud around volcanoes.
Economic importance of bacteria
#Economic importance of bacteria
#Bacteria : economically important as these microorganisms are used by humans for many purposes.
#Beneficial uses of bacteria
#Genetic engineering :
#Biotechnology :
#Food processing :
#Bioremediation
#Industry importance of bacteria
#Fiber industry:
#Medicine (probiotics)
#Agriculture importance
The archaebacteria
group members
Rameen nadeem
Syeda iqra hussain
Hina zamir
Mahnoor khan
Maleeha inayat
Background
Biologists have long organized living things into large groups called kingdoms.
There are six of them:
Archaebacteria
Eubacteria
Protista
Fungi
Plantae
Animalia
Some recent findings…
In 1996, scientists decided to split Monera into two groups of bacteria:
Archaebacteria and Eubacteria
Because these two groups of bacteria were different in many ways scientists created a new level of classification called a DOMAIN.
Now we have 3 domains
Bacteria
Archaea
Eukarya
Kingdom Archaebacteria
Any of a large group of primitive bacteria having unusual cell walls, membrane lipids, ribosomes, and RNA sequences, and having the ability to produce methane and to live in anaerobic, extremely hot, salty, or acidic conditions
The Domain Archaea
“ancient” bacteria
Some of the first archaebacteria were discovered in Yellowstone National Park’s hot springs
Prokaryotes are structurally simple, but biochemically complex
Basic Facts
They live in extreme environments (like hot springs or salty lakes) and normal environments (like soil and ocean water).
All are unicellular (each individual is only one cell).
No peptidoglycan in their cell wall.
Some have a flagella that aids in their locomotion.
Most don’t need oxygen to survive
They can produce ATP (energy) from sunlight
They can survive enormous temperature extremes
They can survive under rocks and in ocean floor vents deep below the ocean’s surface
They can tolerate huge pressure differences
STRUCTURE
Size
Archaea are slightly less than 1 micron long.
A micron is 1/1,000 of a millimeter.
In order to see their cellular features, scientists use powerful electron microscopes.
Shape
Shapes can be spherical or ball shaped and are called coccus.
Others are rod shaped, long and thin, and labeled bacillus.
Variations of cells have been discovered in square and triangular shapes.
STRUCTURE
Locomotion
Some archaea have flagella, hair-like structures that assist in movement.
There can be one or many attached to the cell's outer membrane. Protein networks can also be found on the cell membrane, which allow cells to attach themselves in groups.
Cell Features
Within the cell membrane, the archaea cell contains cytoplasm and DNA, which are in single-looped forms called plasmids.
Most archaeal cells also have a semi-rigid cell wall that helps it to maintain its shape and chemical balance.
This protects the cytoplasm, which is the semi-liquid gel that fills the cell and enables the various parts to function.
STRUCTURE
Phospholipids
The molecules that make up cell membranes are called phospholipids, which act as building blocks for the cell.
In archaea, these molecules are made of glycerol-ether lipids.
Ether Bonding
The ether bonding makes it possible for archaea to survive in environments that are extremely acidic or al
The term "algae" covers many different organisms capable of producing oxygen through photosynthesis (the process of harvesting light energy from the sun to generate carbohydrates).
Algae are a diverse group of aquatic organisms that have the ability to conduct photosynthesis. Certain algae are familiar to most people; for instance, seaweeds (such as kelp or phytoplankton), pond scum or the algal blooms in lakes. However, there exists a vast and varied world of algae that are not only helpful to us, but are critical to our existence.
Archaebacteria kingdom is classified as one of the six kingdoms of life that living organisms are broken into. Archaebacteria are group of single-celled organisms adapted to living under extreme conditions.
Bergey's Manual and it's classification. A brief concised presentation prepared for taking seminar and classes.
Volume II (Edition 2) described more in detail.
Archaebacteria are the oldest organisms living on the Earth. They are
unicellular prokaryotes and belong to the kingdom, Archaea. They were first
discovered in 1977 and classified as bacteria. Most archaebacteria appear like
bacteria, when observed under the microscope. However, they are quite
different from bacteria and eukaryotic organisms.
Archaebacteria are found in very harsh conditions such as in the volcanic vents
or at the bottom of the sea. They can easily survive in such extreme
environment as sea vents releasing sulfide-rich gases, hot springs, or boiling
mud around volcanoes.
Economic importance of bacteria
#Economic importance of bacteria
#Bacteria : economically important as these microorganisms are used by humans for many purposes.
#Beneficial uses of bacteria
#Genetic engineering :
#Biotechnology :
#Food processing :
#Bioremediation
#Industry importance of bacteria
#Fiber industry:
#Medicine (probiotics)
#Agriculture importance
The archaebacteria
group members
Rameen nadeem
Syeda iqra hussain
Hina zamir
Mahnoor khan
Maleeha inayat
Background
Biologists have long organized living things into large groups called kingdoms.
There are six of them:
Archaebacteria
Eubacteria
Protista
Fungi
Plantae
Animalia
Some recent findings…
In 1996, scientists decided to split Monera into two groups of bacteria:
Archaebacteria and Eubacteria
Because these two groups of bacteria were different in many ways scientists created a new level of classification called a DOMAIN.
Now we have 3 domains
Bacteria
Archaea
Eukarya
Kingdom Archaebacteria
Any of a large group of primitive bacteria having unusual cell walls, membrane lipids, ribosomes, and RNA sequences, and having the ability to produce methane and to live in anaerobic, extremely hot, salty, or acidic conditions
The Domain Archaea
“ancient” bacteria
Some of the first archaebacteria were discovered in Yellowstone National Park’s hot springs
Prokaryotes are structurally simple, but biochemically complex
Basic Facts
They live in extreme environments (like hot springs or salty lakes) and normal environments (like soil and ocean water).
All are unicellular (each individual is only one cell).
No peptidoglycan in their cell wall.
Some have a flagella that aids in their locomotion.
Most don’t need oxygen to survive
They can produce ATP (energy) from sunlight
They can survive enormous temperature extremes
They can survive under rocks and in ocean floor vents deep below the ocean’s surface
They can tolerate huge pressure differences
STRUCTURE
Size
Archaea are slightly less than 1 micron long.
A micron is 1/1,000 of a millimeter.
In order to see their cellular features, scientists use powerful electron microscopes.
Shape
Shapes can be spherical or ball shaped and are called coccus.
Others are rod shaped, long and thin, and labeled bacillus.
Variations of cells have been discovered in square and triangular shapes.
STRUCTURE
Locomotion
Some archaea have flagella, hair-like structures that assist in movement.
There can be one or many attached to the cell's outer membrane. Protein networks can also be found on the cell membrane, which allow cells to attach themselves in groups.
Cell Features
Within the cell membrane, the archaea cell contains cytoplasm and DNA, which are in single-looped forms called plasmids.
Most archaeal cells also have a semi-rigid cell wall that helps it to maintain its shape and chemical balance.
This protects the cytoplasm, which is the semi-liquid gel that fills the cell and enables the various parts to function.
STRUCTURE
Phospholipids
The molecules that make up cell membranes are called phospholipids, which act as building blocks for the cell.
In archaea, these molecules are made of glycerol-ether lipids.
Ether Bonding
The ether bonding makes it possible for archaea to survive in environments that are extremely acidic or al
The term "algae" covers many different organisms capable of producing oxygen through photosynthesis (the process of harvesting light energy from the sun to generate carbohydrates).
Algae are a diverse group of aquatic organisms that have the ability to conduct photosynthesis. Certain algae are familiar to most people; for instance, seaweeds (such as kelp or phytoplankton), pond scum or the algal blooms in lakes. However, there exists a vast and varied world of algae that are not only helpful to us, but are critical to our existence.
Archaebacteria kingdom is classified as one of the six kingdoms of life that living organisms are broken into. Archaebacteria are group of single-celled organisms adapted to living under extreme conditions.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
2. ARCHAEBACTERIA
• Archaebacteria are the oldest organism living on
Earth. They are unicellular prokaryotes- microbes
without cell nucleus and any other membrane-
bound organelles in their cells- and belong to the
kingdom,Archae .They were first discovered in
1977 by Carl Woose and George E. Fox and
classified as bacteria. Most archaebacteria appear
like bacteria, when observed under the microscope.
However, ther are quite different from bacteria and
eukaryotes.
3. • Archaebacteria are found in very
harsh conditions such as in the
volcanic vents or at the bottom of the
sea. They can easily survive in such
extreme environment as sea vents
releasing sulfide-rich gases,hot
springs or boiling mud around
volcanoes
4. SUB-GROUPS OF ARCHAEBACTERIA
Methanogens-They produce marsh gas that can be
observed as bubbles in stagnant water. They are also
present in the gut of cattle and termites, since there is no
oxygen there. Methanogens use carbon dioxide as an
electron acceptor to oxidize hydrogen using co-enzymes
like co-enzyme M and methanofuran. These co-enzymes
are very unique to archaebacteria. These bacteria are
rod shaped or spherical, and can be gram positive as
well as negative.
5.
6. Halophiles - are bacteria that can survive in 10 times
the concentration of salt present in sea.Halobacter uses
photophosphorylation for metabolism. They use light
activated ion pumps like bacteriorhodopsin and
halorhodopsin for generation of ion gradients to pump out
ions across the plasma membrane. The energy that is
stored in the electrochemical gradients is converted to
ATP by ATP synthase. They contain bacteriorhodopsin, a
red or orange pigment.
7.
8. Thermoacidophiles -are organisms that can
survive in extremely high temperatures and low
pH. They can survive in 100° Celsius with a
pH of 2. Most of these organisms are
anaerobic in nature.
9.
10. ARCHABECTERIA ARE CLASSIFIED
INTO THE FOLLOWING PHYLA
Phylum Euryarcheota: This is the most studied
division of archaea. It is highly diverse and include
methanogens, which produce methane and are
often found in intestines, halobacteria, which
survive extreme concentrations of salt, and some
extremely thermophilic aerobes and anaerobes.
11. EXAMPLES:
• Methanobrevibacter
smithii -
is a genus of the
Methanobacteriaceae.
The species within
Methanobacteriaceae are
strictly anaerobic aechaea
that produce methane, for
the most part through the
reduction of carbon
12. • Halobacterium
salinarum - is an
extremely halophilic marine
Gram-negative obligate
aerobic archaeon. Despite its
name, this is not a bacterium,
but rather a member of the
domain Archaea. It is found in
salted fish,hides,hypersaline
lakes, and salterns.
13. Phylum Crenarchaeota: It includes
thermophiles and hyperthermophiles.
This archebacteria are mostly found
in the marine environment.
16. Phylum Korarchaeota: This division
consists of hyperthermophiles found in
high temperature hydrothermal
environment.
17. EXAMPLE:
• Candidatus Korarchaeum
Cryptofilum - The archaeal
division Korarchaeota
represents an earlu divergent
branch of the Archaea. This is
a hyperthermophilic archaeon
which has not yet been
isolated in pure culture.
19. EXAMPLES:
• Nitrosopumilus
maritimus - it is one of the
smallest living organisms
at 0.2 micrometers in
diameter.It is capable of
oxidizing ammonia at
levels as slow as 10
nanomolar, near the limit
to sustain its life.
20. • Nitrososphaera Garnesis - It
is observed in small abnormal
cocci groupings and uses its
flagella to move
chhemotaxis.It has a cell
membrane composed of
crenarchaeol, its isomer and a
distinct glycerol dialkyl
glycerol tetraether which is
significan in identifying
ammonia-oxidizing archaea.
21. Phylum Nanoarchaeota - This phylum has a
single representative member named
Nanoarchaeum equitans. This unusual
archebaterium is an obligate symbiont of
another archaea belonging to the genus
Ignicoccus.
22. EXAMPLE:
• Nanoarchaeum
equitans - is a species
of marine Archaea that
was discovered in 2002 in
a hydrothermal vent off the
coast of Iceland on the
Kolbeinsey Ridge by Karl
Stetter.It has been
proposed as the first
species in a new phylum.
24. • They have phylogenetic importance that
helps in studying their homology and
establish their phylogeny.
• Their ability to tolerate extreme conditions
helps researchers learn about the climatic
conditions, environment and their survival
on ancient earth.
25. • Methanogens can grow in biogas fermentors
and decompose cow dung into methane gas
as a by-product. Thus, they are used for
production of domestic gas for cooking.
• Organisms like Methanobacterium
ruminantium are present in the guts of
ruminating animals, helping them digest the
cellulose.
26. • Archaebacteria are also used to synthesize
thermophilic enzymes, restriction enzymes
and are also used as biosensors.
• Archaebacteria have an important role in
many chemical cycles, like carbon cycle,
nitrogen cycle, sulfur cycle.
27. • Due to their extremophilic nature,
archaebacteria have proven to be of great
help in the field of Bioechnology, by
helping in the production of enzymes that
work at very high temperatures, as well as
in the production of some antibiotics.
