This document provides guidance for evaluating and diagnosing heart disease in children. It outlines common presenting signs and symptoms of heart disease in children. It also describes the NADAS criteria for diagnosing heart disease based on physical exam findings. The document gives guidance on performing a bedside evaluation, including vital signs, pulse oximetry, chest X-ray, ECG, and physical exam. It provides information on specific congenital heart defects like their typical age of presentation. It also describes how to manage cyanotic spells and long-term care for older patients with heart disease.