Modelling to support rinderpest outbreaks preparednessExternalEvents
http://www.fao.org/ag/againfo/programmes/en/rinderpest/home.html
http://www-data.fao.org/ag/againfo/programmes/en/empres/event_200116.html
Presentation made during the international meeting titled “Maintaining global freedom from rinderpest” held in FAO-HQ from 20 to 22 January 2016.
OS20 - A multi-species contact-network model: between-farm disease spreading ...EuFMD
1. Researchers developed a stochastic multi-level susceptible-infected model to simulate the spread of disease between farms with bovine, small ruminant, and swine populations in Rio Grande do Sul, Brazil.
2. The model allocated animals to metapopulations (farms) and allowed transmission between susceptible and infected animals based on parameters for a disease like FMD. Initially 10% of animals in each farm were infected.
3. The model analyzed disease spread at the local farm level and evaluated targeted control actions. It found that the highly connected swine network could spread disease more easily but outbreaks could be controlled by removing a low number of farms, while large cattle outbreaks would require removing a very high number
Schistosomiasis is often endemic in rural hard to reach areas of the world, making ground control efforts difficult. Remote sensing is useful because of its ability to capture images over wide temporal and spatial scales, providing risk assessments at low cost. Initial predictive risk models were based off the ecological requirements of the disease’s intermediary host, the snail. An at- tempt at creating a climatologically based risk map for Ghana is presented. The variables chosen were in close agreement with those used in the literature. The limitations of a regional model is its lack of sensitivity to the focality of schistosomiasis. It has been suggested that models can be refined by including factors of both hosts, snails and humans. Creating predictive models that fit an assortment of Schistosoma, snail species, and human factors, over both regional and local scales is necessary to understanding Schistosomiasis in Africa.
The (short) story of brucellosis in western KenyaILRI
A lateral flow assay was used to screen people and animals for brucellosis in western Kenya. The study found a 0.71% seroprevalence in people (n=2116) and 0.31% in cattle (n=893) using the lateral flow assay. However, brucellosis appeared to be commonly diagnosed in local hospitals despite a seroprevalence of less than 0.5% found through further surveillance and a 0.6% seroprevalence in suspected cases (n=827) using the Rose Bengal test. The study suggests brucellosis is over-diagnosed using current methods and that people may not be reliable sentinels for detecting the
This study analyzed how the habitat ranges of one malaria vector (Anopheles punctimacula) and three disease reservoirs (sloths Bradypus variegatus and Choloepus hoffmani, rodent Zygodontomys brevicauda) may change in Panama and Costa Rica under different climate change scenarios in 2050. Even with the most aggressive mitigation of CO2 emissions (RCP 2.6 scenario), preliminary results suggest three of the four species are predicted to experience habitat expansion, which could lead to greater disease incidence in the region and beyond. This is one of the first studies to predict potential expansion of tropical disease vectors and reservoirs within the tropics under climate change.
Presented by Bassirou Bonfoh, Jyldyz Shigaeva and Bernd Steimann at a workshop on an integrated approach to controlling brucellosis in Africa, Addis Ababa, Ethiopia, 29-31 January 2013.
Dr. Bob Morrison, Dr. Carles Vilalta - Update from Swine Health Monitoring Pr...John Blue
Update from Swine Health Monitoring Project (SHMP) - Dr. Bob Morrison, University of Minnesota; Dr. Carles Vilalta, University of Minnesota, from the 2016 North American PRRS Symposium, December 3‐4, 2016, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Based on data from 170K bee collection records from 2000-2016, we build graphs showing the abundance (phenology) of 49 bee genera in the Mid-Atlantic area of North America
Modelling to support rinderpest outbreaks preparednessExternalEvents
http://www.fao.org/ag/againfo/programmes/en/rinderpest/home.html
http://www-data.fao.org/ag/againfo/programmes/en/empres/event_200116.html
Presentation made during the international meeting titled “Maintaining global freedom from rinderpest” held in FAO-HQ from 20 to 22 January 2016.
OS20 - A multi-species contact-network model: between-farm disease spreading ...EuFMD
1. Researchers developed a stochastic multi-level susceptible-infected model to simulate the spread of disease between farms with bovine, small ruminant, and swine populations in Rio Grande do Sul, Brazil.
2. The model allocated animals to metapopulations (farms) and allowed transmission between susceptible and infected animals based on parameters for a disease like FMD. Initially 10% of animals in each farm were infected.
3. The model analyzed disease spread at the local farm level and evaluated targeted control actions. It found that the highly connected swine network could spread disease more easily but outbreaks could be controlled by removing a low number of farms, while large cattle outbreaks would require removing a very high number
Schistosomiasis is often endemic in rural hard to reach areas of the world, making ground control efforts difficult. Remote sensing is useful because of its ability to capture images over wide temporal and spatial scales, providing risk assessments at low cost. Initial predictive risk models were based off the ecological requirements of the disease’s intermediary host, the snail. An at- tempt at creating a climatologically based risk map for Ghana is presented. The variables chosen were in close agreement with those used in the literature. The limitations of a regional model is its lack of sensitivity to the focality of schistosomiasis. It has been suggested that models can be refined by including factors of both hosts, snails and humans. Creating predictive models that fit an assortment of Schistosoma, snail species, and human factors, over both regional and local scales is necessary to understanding Schistosomiasis in Africa.
The (short) story of brucellosis in western KenyaILRI
A lateral flow assay was used to screen people and animals for brucellosis in western Kenya. The study found a 0.71% seroprevalence in people (n=2116) and 0.31% in cattle (n=893) using the lateral flow assay. However, brucellosis appeared to be commonly diagnosed in local hospitals despite a seroprevalence of less than 0.5% found through further surveillance and a 0.6% seroprevalence in suspected cases (n=827) using the Rose Bengal test. The study suggests brucellosis is over-diagnosed using current methods and that people may not be reliable sentinels for detecting the
This study analyzed how the habitat ranges of one malaria vector (Anopheles punctimacula) and three disease reservoirs (sloths Bradypus variegatus and Choloepus hoffmani, rodent Zygodontomys brevicauda) may change in Panama and Costa Rica under different climate change scenarios in 2050. Even with the most aggressive mitigation of CO2 emissions (RCP 2.6 scenario), preliminary results suggest three of the four species are predicted to experience habitat expansion, which could lead to greater disease incidence in the region and beyond. This is one of the first studies to predict potential expansion of tropical disease vectors and reservoirs within the tropics under climate change.
Presented by Bassirou Bonfoh, Jyldyz Shigaeva and Bernd Steimann at a workshop on an integrated approach to controlling brucellosis in Africa, Addis Ababa, Ethiopia, 29-31 January 2013.
Dr. Bob Morrison, Dr. Carles Vilalta - Update from Swine Health Monitoring Pr...John Blue
Update from Swine Health Monitoring Project (SHMP) - Dr. Bob Morrison, University of Minnesota; Dr. Carles Vilalta, University of Minnesota, from the 2016 North American PRRS Symposium, December 3‐4, 2016, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Based on data from 170K bee collection records from 2000-2016, we build graphs showing the abundance (phenology) of 49 bee genera in the Mid-Atlantic area of North America
One Health Hackathon 25/10/2020 - Cyril CaminadeLaiaBent
Climate change can impact vector-borne diseases like malaria through several mechanisms:
1. Temperature affects vector biting rates, development rates, mortality rates, and the extrinsic incubation period inside the vector. Higher temperatures generally increase these rates.
2. Statistical and mechanistic models are used to model the impact of climate factors like temperature and rainfall on vector-borne disease transmission and burden.
3. Early scenarios from the 1990s predicted that climate change could increase malaria risk at higher latitudes and altitudes. However, the impact of climate change on malaria is complex with many other social and environmental factors also influencing transmission.
Stephanie began her path in insect ecology through a 2008 internship with The Nature Conservancy in Nebraska where she studied pollinators. Although her research did not yield significant results, it exposed her to new places and people, and sparked an interest in native bee conservation. After graduating, she took a job with an online grocer where she realized she wanted to apply her insights into agriculture to advance native bee science and conservation. Her research interests involve using ecosystem services and adaptive management to promote native habitat conservation among individual farmers, as pollination is critical to agriculture but relying solely on honey bees is risky, and wild bees can boost their effectiveness. She wants to build on previous valuation studies and integrate adaptive management principles to show farmers
This document is a resume for Andrew Jones, who is expected to graduate in May 2017 with a Doctor of Veterinary Medicine from Virginia-Maryland College of Veterinary Medicine at Virginia Tech. He has a 3.86 GPA and is ranked 5th out of 121 students. His resume outlines his education history, veterinary experience at various clinics and zoos, regulatory experience, research experience, other work experience, skills, honors and awards, and professional affiliations.
Dr. Alex Morrow - Global Coordination of Animal Disease ResearchJohn Blue
Global Coordination of Animal Disease Research - Dr. Alex Morrow, STAR‐IDAZ, from the 2016 North American PRRS Symposium, December 3‐4, 2016, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Tariq Nisar has a Master's degree in Epidemiology and Biostatistics from Texas A&M University and a Bachelor's degree in Dental Surgery from College of Dental Sciences & Research Centre in Bhopal, India. He has worked as an epidemiology and biostatistics intern at the Department of State Health Services in Austin, Texas where he conducted regression analysis to study the association between oil and gas activity and fatal crashes in Texas. Currently he works as a biostatistician and bioinformatics data analyst at the Gastrointestinal Lab at Texas A&M where he has processed and analyzed genomic sequencing and metabolomics data from various treatment and placebo controlled drug and microbiota trials using software like SAS
Alexis Garay has completed an online course in animal behaviour and welfare from the University of Edinburgh. The course introduced an evidence-based approach to assessing the welfare of production, companion, and captive wild animals. It was directed by Professor Nat Waran and involved several other faculty from the University of Edinburgh and Scotland's Rural College.
GermStats - Data Driven Infection Prevention StrategiesIFAH
This document discusses Germstats, a company that provides data-driven infection prevention strategies. It offers environmental data analysis, hand hygiene analysis, infection mapping, and employee audits. Healthcare-associated infections affect over 1.7 million Americans annually and cost the US up to $45 billion. Germstats' software aims to simplify data collection, automate tasks, centralize data, and allow for more proactive management of infections. It performs environmental ATP testing to quantify cleanliness and analyzes hand hygiene trends. Infection mapping tracks infections by location to identify potential cross-contamination. The software also facilitates employee audits and scorecards to improve training feedback.
Insight Health Data Science project - SepRisk: Know Your Sepsis Risk. Save Your Life. (consulting project for Patch'd Medical). This project describes how Cox regression can be used to develop a model to predict the risk of sepsis relative to time,
Building and using the MarineSPEED datasetSamuel Bosch
Presented at the LifeWatch users & stakeholders meeting in January 2018.
Abstract:
We present here MarineSPEED, a benchmark dataset for marine species distribution modelling. Using this dataset we showed that while temperature is a relevant predictor of global marine species distributions, considerable variation in predictor relevance is linked to the species distribution modelling (SDM) set-up.
This benchmark dataset (MarineSPEED) was created by combining records from OBIS and GBIF with environmental data from Bio-ORACLE and MARSPEC and taxonomic information from WoRMS. Predictor relevance was analysed under different variations of SDMs for all combinations of predictors from eight correlation groups.
One health Perspective and Vector Borne DiseasesNanyingi Mark
Vector borne diseases like malaria and Rift Valley fever pose significant risks to human and animal health in Africa. One Health approaches that consider the environmental, animal, and human factors are needed to develop early warning systems. The document discusses developing tools to detect climate sensitive disease outbreaks and assessing environmental and vector characteristics. It also presents models of Rift Valley fever transmission dynamics and the importance of vertical transmission between outbreaks. Spatial distribution models of Rift Valley fever vectors in Kenya were developed using climatic and ecological variables. The results can help target surveillance and control in high-risk areas.
Wildlife-livestock-human interface: recognising drivers of diseaseILRI
This document summarizes a presentation on wildlife-livestock-human disease transmission interfaces in Kenya. It discusses drivers of emerging infectious diseases like climate change and land use changes. Case studies on zoonotic diseases in smallholder farms in Western Kenya and Nipah virus transmission from bats to humans in Asia are described. A study on Malignant Catarrhal Fever transmission from wildebeest to cattle in the Kapiti Plains is also summarized. The presentation concludes that increased contact between wildlife, livestock and humans due to anthropogenic changes is increasing disease risks, and that pathogens may be one step ahead of current prediction capabilities.
Rabies is a fatal viral disease spread through animal bites that kills over 50,000 people per year globally. While vaccination can prevent rabies in exposed people, there are currently no effective antiviral treatments for human rabies infections. This study evaluated two methods, cytopathic effect inhibition and MTT assay, for screening potential anti-rabies drugs in vitro, and found that only cytopathic effect inhibition was suitable for detecting antiviral activity against rabies in infected McCoy cells.
This document summarizes a literature review on Rotavirus A (RVA) infections in Mozambique. Key findings include:
- RVA is a major cause of infant diarrhea in Mozambique, responsible for around 13,000 annual infant deaths.
- Studies have found RVA prevalence between 24-42.4% among children under 5. The virus is most common in the transition between dry and rainy seasons and peaks among infants around 11 months of age.
- Available data comes from hospital studies in Maputo, Sofala, Zambézia, and Nampula provinces. Nampula has the highest reported cases and worse sanitation issues.
- Mozambique introduced the Rotar
Am very excited to start the process of writing this research proposal because malaria is one of the most deadly diseases in Africa, especially in Ghana. so the reason behind this research proposal is that I want us to prevent this disease once and for all in our community. But am not done with this research I will continue it someday.
A Retrospective Disease Surveillance Based Approach in the Investigation and ...Stephen Olubulyera
A Retrospective Disease Surveillance Based Approach in the Investigation and Linkage of Human Brucellosis to Animal Sources: One Health Approach Complementary Strategy Applicable in Nomadic Pastoralism, a Case Study of Turkana County, Kenya.
This research article evaluated the performance of the circulating cathodic antigen immuno-chromatographic test (CCA-ICT) to diagnose Schistosoma mansoni infection in Brazil compared to the standard Kato-Katz stool test. The study analyzed urine and stool samples from 130 individuals in endemic and non-endemic areas and found that the CCA-ICT's sensitivity and specificity depended on whether a trace test result was considered positive or negative. While the CCA-ICT correlated with egg counts, it misdiagnosed approximately 15% of Kato-Katz positive individuals who had light infections. The researchers concluded that the CCA-ICT showed reasonable diagnostic performance but lacked sufficient sensitivity to be used as a standalone
The interconnections between human, animal and environmental healthUniversity of Calgary
The document discusses the interconnectedness of human, animal, and environmental health through a discussion of emerging infectious diseases led by Dr. Baljit Singh and Dr. Susan Catherine Cork. They highlight the importance of a One Health approach and interdisciplinary collaboration to address complex health issues at the human-animal-environment interface, using case studies of vector-borne diseases like Lyme disease and West Nile virus. The discussion emphasizes how disease risks can change with environmental and climatic factors.
One Health Hackathon 25/10/2020 - Cyril CaminadeLaiaBent
Climate change can impact vector-borne diseases like malaria through several mechanisms:
1. Temperature affects vector biting rates, development rates, mortality rates, and the extrinsic incubation period inside the vector. Higher temperatures generally increase these rates.
2. Statistical and mechanistic models are used to model the impact of climate factors like temperature and rainfall on vector-borne disease transmission and burden.
3. Early scenarios from the 1990s predicted that climate change could increase malaria risk at higher latitudes and altitudes. However, the impact of climate change on malaria is complex with many other social and environmental factors also influencing transmission.
Stephanie began her path in insect ecology through a 2008 internship with The Nature Conservancy in Nebraska where she studied pollinators. Although her research did not yield significant results, it exposed her to new places and people, and sparked an interest in native bee conservation. After graduating, she took a job with an online grocer where she realized she wanted to apply her insights into agriculture to advance native bee science and conservation. Her research interests involve using ecosystem services and adaptive management to promote native habitat conservation among individual farmers, as pollination is critical to agriculture but relying solely on honey bees is risky, and wild bees can boost their effectiveness. She wants to build on previous valuation studies and integrate adaptive management principles to show farmers
This document is a resume for Andrew Jones, who is expected to graduate in May 2017 with a Doctor of Veterinary Medicine from Virginia-Maryland College of Veterinary Medicine at Virginia Tech. He has a 3.86 GPA and is ranked 5th out of 121 students. His resume outlines his education history, veterinary experience at various clinics and zoos, regulatory experience, research experience, other work experience, skills, honors and awards, and professional affiliations.
Dr. Alex Morrow - Global Coordination of Animal Disease ResearchJohn Blue
Global Coordination of Animal Disease Research - Dr. Alex Morrow, STAR‐IDAZ, from the 2016 North American PRRS Symposium, December 3‐4, 2016, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Tariq Nisar has a Master's degree in Epidemiology and Biostatistics from Texas A&M University and a Bachelor's degree in Dental Surgery from College of Dental Sciences & Research Centre in Bhopal, India. He has worked as an epidemiology and biostatistics intern at the Department of State Health Services in Austin, Texas where he conducted regression analysis to study the association between oil and gas activity and fatal crashes in Texas. Currently he works as a biostatistician and bioinformatics data analyst at the Gastrointestinal Lab at Texas A&M where he has processed and analyzed genomic sequencing and metabolomics data from various treatment and placebo controlled drug and microbiota trials using software like SAS
Alexis Garay has completed an online course in animal behaviour and welfare from the University of Edinburgh. The course introduced an evidence-based approach to assessing the welfare of production, companion, and captive wild animals. It was directed by Professor Nat Waran and involved several other faculty from the University of Edinburgh and Scotland's Rural College.
GermStats - Data Driven Infection Prevention StrategiesIFAH
This document discusses Germstats, a company that provides data-driven infection prevention strategies. It offers environmental data analysis, hand hygiene analysis, infection mapping, and employee audits. Healthcare-associated infections affect over 1.7 million Americans annually and cost the US up to $45 billion. Germstats' software aims to simplify data collection, automate tasks, centralize data, and allow for more proactive management of infections. It performs environmental ATP testing to quantify cleanliness and analyzes hand hygiene trends. Infection mapping tracks infections by location to identify potential cross-contamination. The software also facilitates employee audits and scorecards to improve training feedback.
Insight Health Data Science project - SepRisk: Know Your Sepsis Risk. Save Your Life. (consulting project for Patch'd Medical). This project describes how Cox regression can be used to develop a model to predict the risk of sepsis relative to time,
Building and using the MarineSPEED datasetSamuel Bosch
Presented at the LifeWatch users & stakeholders meeting in January 2018.
Abstract:
We present here MarineSPEED, a benchmark dataset for marine species distribution modelling. Using this dataset we showed that while temperature is a relevant predictor of global marine species distributions, considerable variation in predictor relevance is linked to the species distribution modelling (SDM) set-up.
This benchmark dataset (MarineSPEED) was created by combining records from OBIS and GBIF with environmental data from Bio-ORACLE and MARSPEC and taxonomic information from WoRMS. Predictor relevance was analysed under different variations of SDMs for all combinations of predictors from eight correlation groups.
Similar to Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health
One health Perspective and Vector Borne DiseasesNanyingi Mark
Vector borne diseases like malaria and Rift Valley fever pose significant risks to human and animal health in Africa. One Health approaches that consider the environmental, animal, and human factors are needed to develop early warning systems. The document discusses developing tools to detect climate sensitive disease outbreaks and assessing environmental and vector characteristics. It also presents models of Rift Valley fever transmission dynamics and the importance of vertical transmission between outbreaks. Spatial distribution models of Rift Valley fever vectors in Kenya were developed using climatic and ecological variables. The results can help target surveillance and control in high-risk areas.
Wildlife-livestock-human interface: recognising drivers of diseaseILRI
This document summarizes a presentation on wildlife-livestock-human disease transmission interfaces in Kenya. It discusses drivers of emerging infectious diseases like climate change and land use changes. Case studies on zoonotic diseases in smallholder farms in Western Kenya and Nipah virus transmission from bats to humans in Asia are described. A study on Malignant Catarrhal Fever transmission from wildebeest to cattle in the Kapiti Plains is also summarized. The presentation concludes that increased contact between wildlife, livestock and humans due to anthropogenic changes is increasing disease risks, and that pathogens may be one step ahead of current prediction capabilities.
Rabies is a fatal viral disease spread through animal bites that kills over 50,000 people per year globally. While vaccination can prevent rabies in exposed people, there are currently no effective antiviral treatments for human rabies infections. This study evaluated two methods, cytopathic effect inhibition and MTT assay, for screening potential anti-rabies drugs in vitro, and found that only cytopathic effect inhibition was suitable for detecting antiviral activity against rabies in infected McCoy cells.
This document summarizes a literature review on Rotavirus A (RVA) infections in Mozambique. Key findings include:
- RVA is a major cause of infant diarrhea in Mozambique, responsible for around 13,000 annual infant deaths.
- Studies have found RVA prevalence between 24-42.4% among children under 5. The virus is most common in the transition between dry and rainy seasons and peaks among infants around 11 months of age.
- Available data comes from hospital studies in Maputo, Sofala, Zambézia, and Nampula provinces. Nampula has the highest reported cases and worse sanitation issues.
- Mozambique introduced the Rotar
Am very excited to start the process of writing this research proposal because malaria is one of the most deadly diseases in Africa, especially in Ghana. so the reason behind this research proposal is that I want us to prevent this disease once and for all in our community. But am not done with this research I will continue it someday.
A Retrospective Disease Surveillance Based Approach in the Investigation and ...Stephen Olubulyera
A Retrospective Disease Surveillance Based Approach in the Investigation and Linkage of Human Brucellosis to Animal Sources: One Health Approach Complementary Strategy Applicable in Nomadic Pastoralism, a Case Study of Turkana County, Kenya.
This research article evaluated the performance of the circulating cathodic antigen immuno-chromatographic test (CCA-ICT) to diagnose Schistosoma mansoni infection in Brazil compared to the standard Kato-Katz stool test. The study analyzed urine and stool samples from 130 individuals in endemic and non-endemic areas and found that the CCA-ICT's sensitivity and specificity depended on whether a trace test result was considered positive or negative. While the CCA-ICT correlated with egg counts, it misdiagnosed approximately 15% of Kato-Katz positive individuals who had light infections. The researchers concluded that the CCA-ICT showed reasonable diagnostic performance but lacked sufficient sensitivity to be used as a standalone
The interconnections between human, animal and environmental healthUniversity of Calgary
The document discusses the interconnectedness of human, animal, and environmental health through a discussion of emerging infectious diseases led by Dr. Baljit Singh and Dr. Susan Catherine Cork. They highlight the importance of a One Health approach and interdisciplinary collaboration to address complex health issues at the human-animal-environment interface, using case studies of vector-borne diseases like Lyme disease and West Nile virus. The discussion emphasizes how disease risks can change with environmental and climatic factors.
Current and future animal vaccine research activities at ILRIILRI
Presentation by Vish Nene at the 12th Biennial Conference of the Society for Tropical Veterinary Medicine (STVM) and the VIII International Conference on Ticks and Tick-borne Pathogens (TTP-8) Cape Town, South Africa 24 to 29 August 2014.
The document summarizes activities of the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP). It outlines the center's mission to improve diagnosis, prevention and control of infectious diseases through training and research. It then provides details on awards received, including grants from Wellcome Trust and scholarships. It discusses the center's program activities like short courses conducted, new master's and PhD programs launched, faculty and student internships, and publications by faculty. In summary, the document reports on WACCBIP's progress in achieving its mission through various training and research initiatives.
The document discusses the Indian Council of Medical Research's (ICMR) efforts to strengthen health research capacity and support innovation to improve health systems in India. Some key points:
1) ICMR aims to translate research into actions to improve population health and achieve universal healthcare by developing cost-effective technologies and innovations.
2) Its strategic framework focuses on strengthening research capacity, organizing data systems, leveraging traditional medicine, enabling evidence-based policy, and using research to strengthen health programs.
3) ICMR supports research on priority health issues like non-communicable diseases, maternal and child health, and infectious diseases through various initiatives and collaborations.
4) It develops and showcases indigenous medical
From Discovery to Delivery: Benchwork to Global Health: Corey CasperUWGlobalHealth
The document discusses the challenges of translating biomedical research into meaningful health improvements, especially for resource-poor countries disproportionately affected by infection-associated cancers. It provides examples from Uganda, which has one of the highest cancer rates in the world but very limited resources and capacity for cancer treatment. Effective translation requires identifying high-burden diseases, conducting etiology research, determining feasibility of implementation, and assessing impact on population health.
This presentation was designed by Mariam Otmani Del Barrio for the VERDAS consortium workshop held on Thursday 2 March at the University of Valle in Cali, Colombia.
The workshop was the Verdas Consortium presentation of its research results, a synthesis of knowledge on urban health interventions for the prevention and control of vector-borne diseases.
- Leptospirosis is a bacterial disease that affects humans and animals worldwide, with the highest incidence in tropical and subtropical regions. It is transmitted primarily through contact with infected animal urine.
- The disease burden is estimated to be over 1 million cases and nearly 60,000 deaths annually worldwide. However, the actual burden may be underreported. Males account for about 80% of cases.
- Prevention strategies include controlling the rodent reservoirs through sanitation and limiting their habitats, provision of clean water, vaccination of livestock, and public education about avoiding contact with contaminated water and soil. Climate change is expanding suitable habitats for rodents and increasing risks of transmission.
This document summarizes a study that used protein microarrays to analyze antibody responses to Plasmodium falciparum (Pf) in residents of two sites in western Kenya with different malaria transmission levels. The study identified 107 Pf proteins that were targets of human antibody responses. Antibody acquisition for these antigens was compared between age groups and sites. Highly immunogenic antigens that elicited stable antibody responses from an early age as well as less immunogenic antigens requiring repeated exposure were identified. A combination of these antigens could potentially be used as serological markers to detect differences in malaria transmission levels between sites.
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document summarizes a study that examined the oral microbial pathogens isolated in newly diagnosed HIV positive patients in Dakar, Senegal. 57 newly diagnosed HIV patients were included in the study. The patients' CD4 counts, viral loads, and oral examinations were analyzed. Common oral lesions found were pseudomembranous candidiasis, xerostomia, and gingivitis. Microbial pathogens isolated included Pseudomonas, Klebsiella, Proteus, Staphylococcus aureus, and Escherichia coli. There was an inverse correlation between CD4 count and viral load. The frequency of oral lesions and microbial isolates increased with higher viral loads. Most patients had CD4 counts below
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document summarizes a study that examined the oral microbial pathogens isolated in newly diagnosed HIV positive patients in Dakar, Senegal. 57 newly diagnosed HIV patients were included in the study. Their CD4 counts, viral loads, and oral examinations were performed. Samples found the most common microbial pathogens were Pseudomonas, Klebsiella, and Proteus. An inverse correlation was found between CD4 count and viral load. The frequency of oral lesions and microbial isolates increased with higher viral loads. 70% of patients had CD4 counts below 500. The study concludes maintaining a low oral microbial load is important for preventing opportunistic infections in HIV patients.
Public health is dependent on animal health in rural areas because poor animal health directly affects the human food supply. Veterinary public health entails the diagnosis, surveillance, epidemiology, control, prevention and elimination of Zoonoses. Unsatisfactory implementation of stringent disease control, meat inspectorate and drug dispensation legislations prevents the efficient production of food of animal origin; creating obstacles to international trade in animals and animal products and hence an impediment to overall socioeconomic development
The document discusses the Center for Animal Disease Control (CADIC) in Miyazaki, Japan. CADIC was established in 2011 following an outbreak of foot-and-mouth disease that caused large economic losses. The center aims to develop international networks for disease control and conducts research on various zoonotic diseases including foot-and-mouth disease, avian influenza, and African swine fever. It has divisions focused on research, inspection, cooperation and education.
Similar to Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health (20)
Small ruminant keepers’ knowledge, attitudes and practices towards peste des ...ILRI
Presentation by Guy Ilboudo, Abel Sènabgè Biguezoton, Cheick Abou Kounta Sidibé, Modou Moustapha Lo, Zoë Campbell and Michel Dione at the 6th Peste des Petits Ruminants Global Research and Expertise Networks (PPR-GREN) annual meeting, Bengaluru, India, 28–30 November 2023.
Small ruminant keepers’ knowledge, attitudes and practices towards peste des ...ILRI
Poster by Guy Ilboudo, Abel Sènabgè Biguezoton, Cheick Abou Kounta Sidibé, Modou Moustapha Lo, Zoë Campbell and Michel Dione presented at the 6th Peste des Petits Ruminants Global Research and Expertise Networks (PPR-GREN) annual meeting, Bengaluru, India, 29 November 2023.
A training, certification and marketing scheme for informal dairy vendors in ...ILRI
Presentation by Silvia Alonso, Jef L. Leroy, Emmanuel Muunda, Moira Donahue Angel, Emily Kilonzi, Giordano Palloni, Gideon Kiarie, Paula Dominguez-Salas and Delia Grace at the Micronutrient Forum 6th Global Conference, The Hague, Netherlands, 16 October 2023.
Milk safety and child nutrition impacts of the MoreMilk training, certificati...ILRI
Poster by Silvia Alonso, Emmanuel Muunda, Moira Donahue Angel, Emily Kilonzi, Giordano Palloni, Gideon Kiarie, Paula Dominguez-Salas, Delia Grace and Jef L. Leroy presented at the Micronutrient Forum 6th Global Conference, The Hague, Netherlands, 16 October 2023.
Preventing the next pandemic: a 12-slide primer on emerging zoonotic diseasesILRI
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
Preventing preventable diseases: a 12-slide primer on foodborne diseaseILRI
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like anxiety and depression.
Preventing a post-antibiotic era: a 12-slide primer on antimicrobial resistanceILRI
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise boosts blood flow, releases endorphins, and promotes changes in the brain which help enhance one's emotional well-being and mental clarity.
Food safety research in low- and middle-income countriesILRI
Presentation by Hung Nguyen-Viet at the first technical meeting to launch the Food Safety Working Group under the One Health Partnership framework, Hanoi, Vietnam, 28 September 2023
The Food Safety Working Group (FSWG) in Vietnam was created in 2015 at the request of the Deputy Prime Minister to address food safety issues in the country. It brings together government agencies, ministries, and development partners to facilitate joint policy dialogue and improve food safety. Over eight years of operations led by different organizations, the FSWG has contributed to various initiatives. However, it faces challenges of diminished government participation over time and dependence on active members. Going forward, it will strengthen its operations by integrating under Vietnam's One Health Partnership framework to better engage stakeholders and achieve policy impacts.
Reservoirs of pathogenic Leptospira species in UgandaILRI
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Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health
1. Unlocking livestock development potential through science, influence and capacity development
ILRI APM, Addis Ababa, 15-17 May 2013
Developing capacity Influencing decisions
Mapping
distribu.ons
of
.cks
and
.ck-‐borne
diseases
in
Africa:
effects
of
climate
change
and
the
implica.ons
for
human
and
animal
health.
This
document
is
licensed
for
use
under
a
Crea3ve
Commons
A6ribu3on-‐Noncommercial-‐Share
Alike
3.0
Unported
License
May
2013
3 strategic lessons on:
! Aiding
.ck
and
.ck-‐borne
disease
control
protocols
Rothen,
J.,
Bishop,
R.,
Mwaura,
S,
Pflüger,
V.,
Daubenberger,
C.,
Olds,
C.
Delivering science
THE
PROBLEM
Tick
distribu.ons
are
determined
by
clima.c
factors
such
as
temperature,
precipita.on
and
humidity.
Tick
distribu.ons
are
shiKing
drama.cally
due
to
climate
change.
Consequently,
the
epidemiology
of
.ck-‐borne
diseasess
are
changing
with
far
reaching
implica.ons
for
animal
and
human
health.
Maps
ploMng
current
.ck
distribu.ons
in
Africa
are
needed
to
understand
and
predict
.ck-‐borne
diseases.
Matrix-‐assisted
laser
desorp.on/ioniza.on-‐Time
of
flight
(MALDI-‐TOF)
mass
spectroscopy
is
able
to
iden.fy
.ck
species
cheaper
and
faster
than
other
molecular
techniques.
! Mapping
.cks
for
human
and
livestock
health
! Developing
databases
for
.ck
iden.fica.on
! Developing
predic.on
models
for
.ck
and
.ck-‐borne
disease
distribu.on
! Training
human
and
veterinary
health
professionals
in
.ck
iden.fica.on
! Mentoring
students
THE
SOLUTION
Collect
.cks
from
livestock,
humans
and
companion
animals
as
well
as
field
traps.
Iden.fy
.cks
using
MALDI-‐TOF.
Iden.fy
any
.ck-‐borne
diseases
present
in
collected
.cks.
Create
new
distribu.on
maps
for
.ck
species
within
Africa.
Create
models
for
further
.ck
and
.ck-‐borne
disease
distribu.ons.
THE
PROGRESS
Reference
MALDI-‐TOF
profies
have
been
created
for
economically
important
.cks
of
livestock
in
Africa.
Field
.ck
species
correctly
iden.fied
in
a
‘proof
of
concept’
experiment.
Large
scale
.ck
collec.ons
should
be
carried
out
covering
various
geographic
areas
within
Africa
and
the
data
used
to
update
.ck
distribu.on
maps.
COLLABORATORS
Claudia
Daubenberger,
Swiss
Tropical
and
Public
Health
Ins.tute,
Switzerland.
Valen.n
Pflüger
and
Julian
Rothen,
Mabritec,
Switzerland.