Antifungals in Medicine discusses the classification, risk factors, diagnosis and treatment of fungal infections. Fungal infections can be superficial, subcutaneous or systemic depending on the immune response. Common fungal diseases include dermatophytosis, candidiasis, aspergillosis, cryptococcosis and mucormycosis affecting organs like the lungs, brain and skin. Diagnosis involves histopathology, culture, biomarkers and imaging. Antifungal drugs include polyenes, azoles, echinocandins and flucytosine which have different mechanisms of action and spectra of activity. Proper treatment depends on early diagnosis, source control, and guidelines for prophylaxis, preempt