This document discusses drugs that act on the renin angiotensin system, including angiotensin converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs). It provides details on the mechanism of action, therapeutic uses and side effects of ACEIs such as Captopril, Enalapril, and Lisinopril. It also summarizes the mechanism of action of ARBs such as Losartan and Valsartan, and their uses in treating conditions like high blood pressure and heart failure.