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HISTORY OF
ANESTHESIA
Presented by
Dr. Md Mizan Ullah
Dept of anesthesia ,analgesia,ICM
Shaheed Suhrawardy Medical college
Hospital
WHY NEED H/O
ANESTHESIA
 Understanding of our past guides our future
 The history of surgery link to the development
of appropriate anesthetic technique and so H/o
surgery follows the history of anesthesia
 We are all part of it
WHAT IS ANESTHESIA
 Greek an- without and aesthesia – sensation
refers to the inhibition of sensation
 Origin of anesthesia :
– Oliver Wendell Holmes Sr 1846
 Insensitivity to pain , especially as artificially
induced by the administration of gases or the
injection of drugs before surgical operation
WHY ANESTHESIA
 Loss of awareness/Amnesia
 Analgesia
 Reduce the movement in response to stimuli
 Minimize the autonomic response to surgical
stimuli
 Muscle relaxant
 Autonomic regulation
HISTORY OF
ANESTHESIA
 Pre- 1846: – The foundation of anesthesia
 1846-1900: Establishment of anesthesia
 20th
century: Consolidation and growth
 21st
century: – The future
PRE- 1846
THE FOUNDATION OF ANESTHESIA
METHOD OF ANESTHESIA
 Drug method
 Non-drug method
DRUGS METHOD
 Alcohol
 Opium
 Hyoscine
 Cannabis
 Cocaine
NON DRUGE METHOD
 Cold
 Concussion
 Carotid compression
 Nerve compression
 Mesmeric Magnetism
 Hypnosis
 Blood letting
ANCIENT ANESTHESIA
 Status of surgery
– Barber shop surgery
 Type of surgery
– Amputation and dental
extraction
– No antiseptic
– Appalling mortality
 Indication
– Unbearable pain
– Crippling deformity
– Imminent death
HISTORICAL PERSON IN
ANESTHESIA
WILLIAM T G MORTON
 First GA was given by
use diethyl ether
 Inventor and Revealer
of inhalational
anesthesia : Before
whom ,in all time
surgery was agony.
1846 (16TH
OCTOBER)
 Anesthetist
– William T G Morton
 Agent: Ether
 Patient
– Gilbert Abort
 Operation
– Excision of tumor
under jaw
 Surgeon
– John Collin Warren
JOHN SNOW
 Use chloroform to deliver
the last two children of
Queen Victoria
 First anesthesiologist
 Describe the stage of
ether anesthesia
 Improve the method of
administration of ether
and chloroform
HISTORICAL PLACE
Boston memorial Massachusetts memorial
ETHER
 1540: Synthesized and named “sweet oil of
vitriol” by Valerius Cordus
 Renamed ether by: Frobenius
 1744 : Matthew discovered it inhalational
properties
 1818: Michel Faraday discovered “narcotic
effect”
Cont….
 1842 :
– first use as clinical
anesthetics in USA
 1846 (16th
October):
– first public demonstration
in Boston
NITROUS OXIDE
 Joseph Priestley
– First prepared by 1773
 Humphrey Davy
– applied N2O on himself
by face mark deign for
industry.
– Noted it analgesic
properties 1800
CHLOROFORM
 1831: Synthesized :
 1847: Anesthetic properties discovered
 1847 : First clinical use London
 1847: James Young Simpson use it for
obstetric anesthesia
 1847: John snow regulating inhaler
 1847: Hannah Greener first anesthetic death
20TH
CENTURY
CONSOLIDATION AND GROWTH
CONT…
 Intubation and airway advance
 Anesthetic equipment
 Monitoring
 Drug advance
 Pain management
 Intensive care
 Local anesthesia
 Organization of specialty
INTUBATION & AIRWAY
ADVANCE
 1919: Endotrachial intubation
 1928: blind nasal intubation
 1950: PVC tube introduce
 1954: Classification of breathing circuit
 1972: Bain circuit
 1980: LMA
ANESTHETIC
EQUIPMENT
 1908: Rota meter
 1917: Boyles machine
 1938: Mechanical ventilation
 1940: Oxford vaporizer
MONITORING
 Bp Monitor: MGH
 1946: O2 analyzer
 1949: Nerve stimulator
 1956: Blood gas monitor
DRUG ADVANCE
 1911: Balance anesthesia
 1942: Curare
 1951: Suxamethonium
 1956: Halothane
 1964: Entonox
 1980: fentanyl/Propofol/vecuronium
 1990: Sevuflurane
LOCAL ANESTHESIA
 Definition:
– Any substance that prevent the conduction of nerve
impulse is called local anesthetics.
 Substance that block the voltage- activate Na+
channel.
CONT…
 Cocaine:
– Naturally occurring compound, indigenous
to the Andes mountains.
– Alkaloid obtain from:
 Leaves of Erythroxylum coca
– First LA to discover 1800
– Only naturally occurring LA
– Koller use as a LA in 1883 in eye
– Hall introduce it in dentistry
CONT……
 Procaine :
– Developed : 1904
– First synthetic LA
 Lidocaine :
– Discovered by : Lofgren 1943
– Market available : 1947 (xylocaine)
– First amide LA
– Most widely use cocaine derivatives
 Bupivacaine :
– Discovered : 1957
– Market available : 1965
REGIONAL ANESTHESIA
 Spinal anesthesia :
– 1885: by Leonard Corning
– 1898: August Bier
 Epidural : 1921
 IVRA:
– 1908 by “August Bier”
– Use procaine in a vein
between two
tourniquets
August Bier
ANESTHESIA IN BD
 Local anesthesia and regional block was done
by surgeon themselves at DMCH
 GA was done under supervision of surgeon
and use by the house surgeon by respective
department
 Dr. Beni Madhab Basak : GA
 Dr. S M Mukhlesur rahman 1948
CONT….
 First post graduate
– Dr A.S.M.A Quader (DA) London
 1951:
– Dr. A Quader has been in charge Department of
anesthesia DMC
 Prof S N Samad Chowdhury
 DA (London,) FCPS, FFARCS
– was long time president of BSA and has a great
contribution of expansion of anesthesia in BD
MANPOWER IN BD
 1947: No recognized trainee anesthesiologist
 1948: Two self trained and in 1951 one ,total
three with one recognized
 1980: gradual increase the interest in this
field due to national demand . still improving
but slow.
POST GRAGUATE
 DA
– Dr. Fakhrun Nissa Dr. Dilip Kumar Dar
 MCPS:
– Dr. M Khalilur Rahman 1976
 FCPS:
– Dr. Selim M Jahangir 1983
 MD:
– Dr. Abdul Hai 1987
ANESTHESIA EXPANSION IN
BD
 Pre –operative management
 Pain clinic
 Intensive care unit
 Palliative care
ICU started in 1985 in DMCH with six bed
BSA
 Established: 1974
 President : Dr. K S A M Quader
 Secretary: Dr. Shafiqur Rasul
 Journal: 1987 Dr. K M Iqbal was editor
CONCLUSION
 Now a day complicated surgical procedure is
possible due to improvement of anesthesia
 Still we are lacking some basic infrastructural
problem like
 Proper placement and distribution of man
power
 Availability of equipment
 Standard monitoring
 However we are very much hopeful and
awaiting for our golden future
THANK YOU

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Anesthesia history 1

  • 1. HISTORY OF ANESTHESIA Presented by Dr. Md Mizan Ullah Dept of anesthesia ,analgesia,ICM Shaheed Suhrawardy Medical college Hospital
  • 2. WHY NEED H/O ANESTHESIA  Understanding of our past guides our future  The history of surgery link to the development of appropriate anesthetic technique and so H/o surgery follows the history of anesthesia  We are all part of it
  • 3. WHAT IS ANESTHESIA  Greek an- without and aesthesia – sensation refers to the inhibition of sensation  Origin of anesthesia : – Oliver Wendell Holmes Sr 1846  Insensitivity to pain , especially as artificially induced by the administration of gases or the injection of drugs before surgical operation
  • 4. WHY ANESTHESIA  Loss of awareness/Amnesia  Analgesia  Reduce the movement in response to stimuli  Minimize the autonomic response to surgical stimuli  Muscle relaxant  Autonomic regulation
  • 5. HISTORY OF ANESTHESIA  Pre- 1846: – The foundation of anesthesia  1846-1900: Establishment of anesthesia  20th century: Consolidation and growth  21st century: – The future
  • 6. PRE- 1846 THE FOUNDATION OF ANESTHESIA
  • 7. METHOD OF ANESTHESIA  Drug method  Non-drug method
  • 8. DRUGS METHOD  Alcohol  Opium  Hyoscine  Cannabis  Cocaine
  • 9. NON DRUGE METHOD  Cold  Concussion  Carotid compression  Nerve compression  Mesmeric Magnetism  Hypnosis  Blood letting
  • 10. ANCIENT ANESTHESIA  Status of surgery – Barber shop surgery  Type of surgery – Amputation and dental extraction – No antiseptic – Appalling mortality  Indication – Unbearable pain – Crippling deformity – Imminent death
  • 12. WILLIAM T G MORTON  First GA was given by use diethyl ether  Inventor and Revealer of inhalational anesthesia : Before whom ,in all time surgery was agony.
  • 13. 1846 (16TH OCTOBER)  Anesthetist – William T G Morton  Agent: Ether  Patient – Gilbert Abort  Operation – Excision of tumor under jaw  Surgeon – John Collin Warren
  • 14. JOHN SNOW  Use chloroform to deliver the last two children of Queen Victoria  First anesthesiologist  Describe the stage of ether anesthesia  Improve the method of administration of ether and chloroform
  • 15. HISTORICAL PLACE Boston memorial Massachusetts memorial
  • 16. ETHER  1540: Synthesized and named “sweet oil of vitriol” by Valerius Cordus  Renamed ether by: Frobenius  1744 : Matthew discovered it inhalational properties  1818: Michel Faraday discovered “narcotic effect”
  • 17. Cont….  1842 : – first use as clinical anesthetics in USA  1846 (16th October): – first public demonstration in Boston
  • 18. NITROUS OXIDE  Joseph Priestley – First prepared by 1773  Humphrey Davy – applied N2O on himself by face mark deign for industry. – Noted it analgesic properties 1800
  • 19. CHLOROFORM  1831: Synthesized :  1847: Anesthetic properties discovered  1847 : First clinical use London  1847: James Young Simpson use it for obstetric anesthesia  1847: John snow regulating inhaler  1847: Hannah Greener first anesthetic death
  • 21. CONT…  Intubation and airway advance  Anesthetic equipment  Monitoring  Drug advance  Pain management  Intensive care  Local anesthesia  Organization of specialty
  • 22. INTUBATION & AIRWAY ADVANCE  1919: Endotrachial intubation  1928: blind nasal intubation  1950: PVC tube introduce  1954: Classification of breathing circuit  1972: Bain circuit  1980: LMA
  • 23. ANESTHETIC EQUIPMENT  1908: Rota meter  1917: Boyles machine  1938: Mechanical ventilation  1940: Oxford vaporizer
  • 24. MONITORING  Bp Monitor: MGH  1946: O2 analyzer  1949: Nerve stimulator  1956: Blood gas monitor
  • 25. DRUG ADVANCE  1911: Balance anesthesia  1942: Curare  1951: Suxamethonium  1956: Halothane  1964: Entonox  1980: fentanyl/Propofol/vecuronium  1990: Sevuflurane
  • 26. LOCAL ANESTHESIA  Definition: – Any substance that prevent the conduction of nerve impulse is called local anesthetics.  Substance that block the voltage- activate Na+ channel.
  • 27. CONT…  Cocaine: – Naturally occurring compound, indigenous to the Andes mountains. – Alkaloid obtain from:  Leaves of Erythroxylum coca – First LA to discover 1800 – Only naturally occurring LA – Koller use as a LA in 1883 in eye – Hall introduce it in dentistry
  • 28. CONT……  Procaine : – Developed : 1904 – First synthetic LA  Lidocaine : – Discovered by : Lofgren 1943 – Market available : 1947 (xylocaine) – First amide LA – Most widely use cocaine derivatives  Bupivacaine : – Discovered : 1957 – Market available : 1965
  • 29. REGIONAL ANESTHESIA  Spinal anesthesia : – 1885: by Leonard Corning – 1898: August Bier  Epidural : 1921  IVRA: – 1908 by “August Bier” – Use procaine in a vein between two tourniquets August Bier
  • 30. ANESTHESIA IN BD  Local anesthesia and regional block was done by surgeon themselves at DMCH  GA was done under supervision of surgeon and use by the house surgeon by respective department  Dr. Beni Madhab Basak : GA  Dr. S M Mukhlesur rahman 1948
  • 31. CONT….  First post graduate – Dr A.S.M.A Quader (DA) London  1951: – Dr. A Quader has been in charge Department of anesthesia DMC  Prof S N Samad Chowdhury  DA (London,) FCPS, FFARCS – was long time president of BSA and has a great contribution of expansion of anesthesia in BD
  • 32. MANPOWER IN BD  1947: No recognized trainee anesthesiologist  1948: Two self trained and in 1951 one ,total three with one recognized  1980: gradual increase the interest in this field due to national demand . still improving but slow.
  • 33. POST GRAGUATE  DA – Dr. Fakhrun Nissa Dr. Dilip Kumar Dar  MCPS: – Dr. M Khalilur Rahman 1976  FCPS: – Dr. Selim M Jahangir 1983  MD: – Dr. Abdul Hai 1987
  • 34. ANESTHESIA EXPANSION IN BD  Pre –operative management  Pain clinic  Intensive care unit  Palliative care ICU started in 1985 in DMCH with six bed
  • 35. BSA  Established: 1974  President : Dr. K S A M Quader  Secretary: Dr. Shafiqur Rasul  Journal: 1987 Dr. K M Iqbal was editor
  • 36. CONCLUSION  Now a day complicated surgical procedure is possible due to improvement of anesthesia  Still we are lacking some basic infrastructural problem like  Proper placement and distribution of man power  Availability of equipment  Standard monitoring  However we are very much hopeful and awaiting for our golden future