This document provides an overview of the anatomy of the nose. It discusses the bony and cartilaginous structures that make up the external nose, as well as the muscles of the nose. Internally, it describes the nasal vestibule, cavity, lateral nasal wall, septum, roof and floor. It then discusses the turbinates and meatuses, paranasal sinuses, nerves, blood supply and mucosa of the nose.
The pharynx is a hollow tube that starts behind the nose, goes down the neck, and ends at the top of the trachea and esophagus. The three parts of the pharynx are the nasopharynx, oropharynx, and hypopharynx.
The pharynx is a hollow tube that starts behind the nose, goes down the neck, and ends at the top of the trachea and esophagus. The three parts of the pharynx are the nasopharynx, oropharynx, and hypopharynx.
Introduction
Functions
Development
Structure
Nasal cavity
Nasal septum
Lateral wall
Applied anatomy and pathology –
- danger area of nose
- nose bleeding
- foreign body in nose
- developmental nasal deformities
- nasal polyps
- mouth breathing
- rhinitis
External ear,tympanic membrane and auditory tube Dr.N.Mugunthan.M.S.,mgmcri1234
External ear,tympanic membrane and auditory tube - Lecture by Dr.N.Mugunthan.M.S.,Associate Professor, Mahatma Gandhi Medical College & Research Institute, Pondicherry,
Sri Balaji Vidyapeeth University.
surgical anatomy of nose is a humble attempt to make the anatomy of nose simpler and easy for medical students and fellow physicians. at the end of the presentation the students will be able to identify all the structures.
Introduction
Functions
Development
Structure
Nasal cavity
Nasal septum
Lateral wall
Applied anatomy and pathology –
- danger area of nose
- nose bleeding
- foreign body in nose
- developmental nasal deformities
- nasal polyps
- mouth breathing
- rhinitis
External ear,tympanic membrane and auditory tube Dr.N.Mugunthan.M.S.,mgmcri1234
External ear,tympanic membrane and auditory tube - Lecture by Dr.N.Mugunthan.M.S.,Associate Professor, Mahatma Gandhi Medical College & Research Institute, Pondicherry,
Sri Balaji Vidyapeeth University.
surgical anatomy of nose is a humble attempt to make the anatomy of nose simpler and easy for medical students and fellow physicians. at the end of the presentation the students will be able to identify all the structures.
The presentation is a summary of the bones of head and neck showing the main bones n its relations and a short applied aspect of the skull bones. It depicts a gross anatomy of the skull bones which includes the bones forming calvaria or brain box and also the facial skeleton.
Ct anatomy of paranasal sinuses( PNS) pk.pdf pptDr pradeep Kumar
This presentation includes cross sectional anatomy like axial,saggital and coronal images of paranasal sinuses and most important variation of paranasal sinus.This help alot. Must read topic for radiology resident. Thanks
Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Nose & Paranasal sinuses.All Good Things
Dentist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Nose & Paranasal sinuses.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
Subscribe our channel on youtube - Copy and paste this URL. https://www.youtube.com/channel/UC_gylEXTrjmEbbOTSXjuZ4Q/videos?view_as=public
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
5. Nasal skin
Upper skin is loose while lower is thick and
adherent
Rhinophyma: Hypertrophy of sebaceous
glands
akk
6. It consists of
Nasal vestibule
Nasal cavity
- Lateral nasal wall
- Nasal septum
- Roof of nose
- Floor of nose
- Lining of internal nose
akk
7. Anterior and inferior part of nasal cavity
Lined by skin which contains sebaceous
glands and hair (vibrissae)
Upper limit on lateral wall is marked by limen
nasi
Medial wall is formed by columella and lower
part of nasal septum
In recurrent vestibulitis always rule out DM
akk
9. The Turbinates
- They are scroll-like bony projections
covered by mucous membrane
- Superior, Middle & Inferior (sometimes
Supreme)
The Meatuses
- These are spaces below the turbinates
- Superior, Middle & Inferior
akk
11. Inferior turbinate
- It is a separate bone
- Nasolacrimal duct open into inferior meatus
- NLD guarded by Hasner’s valve
Middle turbinate
- It is a part of ethmoid bone
- Attached to lateral wall (S shaped) by
ground/basal lamella
Middle meatus
- Uncinate process
akk
13. Infundibulum
- Space limited medially by uncinate process
and laterally by lamina papyracea
- Natural ostium of maxillary sinus is sitauted
in the lower part of infundibulum
Bulla ethmoidalis
- Ethmoidal cell situated behind uncinate
- Anterior surface forms the posterior
boundary of hiatus semiluaris
- Can be pneumatised or solid
akk
14. Bulla ethmoidalis
- Suprabullar and retrobullar space together
form the lateral sinus of Grunwald
- Cleft like communication between bulla and
skull base is called hiatus semilunaris
superior
Agger nasi cells are situated anterior to the
attachment of MT
Concha bullosa is pneumatised MT
Haller cells situated at roof of maxillary sinus
(infraorbital cells)
akk
15. Superior turbinate is also a part of ethmoid
bone
Posterior ethmoid cells (1 to 5) open into it
Onodi cell is a posterior ethmoid cell which
may grow posterior to sphenoid. Optic nerve
is related to its lateral wall
Sphenoethmoidal recess is situated above the
superior turbinate. Sphenoid sinus opens into
it
akk
18. Olfactory nerves
- Carry sense of smell
- End in olfactory bulb
- These nerves carry sheaths of dura, pia &
arachnoid with them into the nose. Injury to
these nerves can cause CSF rhinorrhoea or
meningitis
Nerves of common sensation
- Anterior Ethmoidal nerve (anterior and superior
part of nasal cavity)
- Branches of sphenopalatine ganglion (posterior
2/3rd of nasal cavity)
- Branches of infra-orbital nerve (vestibule)
akk
19. Autonomic Nerves
- Parasympathetic fibres (Vasodilation)
Come from GSPN travel in nerve of
pterygoid canal Sphenopalatine ganglion
- Sympathetic fibres (Vasoconstriction)
Come from upper thoracic segments of spinal
cord Superior cervical ganglion travel
in nerve of pterygoid canal Sphenopalatine
ganglion
akk
23. Columellar Septum
- Formed by medial crura of alar cartilages
Membranous Septum
Septum proper
- Perpendicular plate of ethmoid
- Vomer
- Septal (quadrilateral) cartilage
- Minor bones: crest of nasal bones, nasal
spine of frontal bone, rostrum of sphenoid,
crest of palatine bones & maxilla, and the
anterior nasal spine of maxilla
akk
26. Internal carotid system
- Anterior ethmoidal Branches of
- Posterior ethmoidal Ophthalmic artery
External carotid system
- Sphenopalatine artery (branch of maxillary)
gives nasopalatine and posterior medial nasal
branches
- Septal branch of greater palatine artery
(branch of maxillary artery)
- Septal branch of superior labial artery
(branch of facial artery)
akk
27. Little’s Area
Located at antero-inferior part of septum
Formed by anterior ethmoidal,
sphenopalatine, greater palatine and septal
branch of superior labial artery
Commonest site for epistaxis
akk
29. Roof
- Anterior sloping part formed by nasal bones
- Posterior sloping part formed by body of
sphenoid
- Middle horizontal part formed by cribriform
plate
Floor
- Palatine process of maxilla (anterior 3/4th)
- Horizontal plate of palatine bone (posterior
1/4th)
akk
30. Vestibule lined by skin
Olfactory region present in upper 1/3rd of
lateral wall, roof and upper 1/3rd of septum
Respiratory region is the lower 2/3rd of nasal
cavity
akk
