The document discusses the anatomy and physiology of the cerebral circulation and cerebrospinal fluid (CSF). It describes the major arteries and veins that make up the brain's blood supply, including the internal carotid arteries, vertebral arteries, and circle of Willis. It explains how blood flows into the anterior and posterior circulations to supply different brain regions. It also outlines the ventricles and flow of CSF within the brain and spinal cord.
The document discusses the blood supply of the brain. It notes that the brain requires continuous oxygenated blood flow. There are two main arterial systems that supply the brain - the carotid system and vertebrobasilar system. The carotid system includes the internal carotid arteries which provide around 80% of the brain's blood supply. The vertebrobasilar system includes the vertebral arteries which join to form the basilar artery and provides the remaining 20% of blood supply. These two systems anastomose to form the cerebral arterial circle, also known as the Circle of Willis, at the base of the brain.
The spinal cord receives its blood supply from the anterior and posterior spinal arteries as well as radicular arteries. Venous drainage occurs through six irregular plexiform channels along the midlines and roots that drain into the epidural venous plexus and Batson's plexus, which may transport tumor cells. The anterior spinal artery arises from the vertebral artery and supplies the anterior two-thirds of the cord. Posterior spinal arteries from the vertebra arteries supply the posterior horns and dorsal funiculi. Radicular arteries from the intercostal arteries supply peripheral areas and anastomose with the anterior and posterior spinal arteries.
The document discusses cerebral circulation and the blood supply to the brain. It covers the functional anatomy of cerebral blood vessels including the internal carotid arteries and vertebral arteries which form the Circle of Willis. It also discusses the unique properties of brain capillaries and the blood-brain barrier. Measurement techniques for cerebral blood flow like Kety's method and radioactive methods are explained. Factors regulating cerebral blood flow including cerebral perfusion pressure, cerebral vascular resistance, and autoregulation are outlined. Finally, some applied aspects like stroke are briefly covered.
The document summarizes the development, anatomy, and histology of the pons and midbrain. It describes that the pons develops from the metencephalon and receives cells from the myelencephalon. The midbrain develops from the mesencephalon. The document then provides detailed descriptions of the structures, tracts, nuclei, and blood supply of both the pons and midbrain through multiple sections and diagrams.
The thoracic aorta begins where the aortic arch ends at the fourth thoracic vertebrae and extends down to the diaphragm. It supplies blood to the thoracic cavity and has several important branches including the bronchial arteries which supply the lungs, esophageal arteries which supply the esophagus, and posterior intercostal arteries which supply the spaces between the ribs. The thoracic aorta also gives off mediastinal and pericardial branches before passing through the diaphragm and becoming the abdominal aorta.
This document discusses the anatomy and physiology of cutaneous blood flow regulation. It notes that cutaneous blood flow at rest is 10-15 ml/min/100g of skin, falling to 1 ml/min/100g with cold exposure and increasing tenfold with heat exposure. Blood flow is primarily regulated by the sympathetic nervous system. Exposure to heat causes arteriole dilation, cutaneous vessel dilation, sweating, and bradykinin-induced dilation. Exposure to cold triggers vasoconstriction. Various reflexes and cortical mechanisms also influence blood flow regulation and skin color changes.
The brain stem is located between the cerebrum and spinal cord, and consists of the midbrain, pons, and medulla oblongata. The midbrain connects the forebrain to the pons and cerebellum. It contains important centers for visual and auditory reflexes, and gives rise to the trochlear nerve. Key structures in the midbrain include the superior and inferior colliculi, oculomotor nucleus, red nucleus, and substantia nigra. The midbrain serves to relay motor and sensory signals between the spinal cord and forebrain.
The cerebrospinal fluid (CSF) provides mechanical, chemical, and circulatory protection to the brain and spinal cord. It is formed by the choroid plexuses in the ventricles at a rate of around 550 ml per day, circulates through the ventricles and subarachnoid space, and is absorbed by arachnoid villi into venous sinuses. Disorders like hydrocephalus can occur if CSF circulation is obstructed or production/absorption is abnormal. Lumbar puncture and cisternal puncture are used to collect CSF samples or administer drugs into the CSF pathways.
The document discusses the blood supply of the brain. It notes that the brain requires continuous oxygenated blood flow. There are two main arterial systems that supply the brain - the carotid system and vertebrobasilar system. The carotid system includes the internal carotid arteries which provide around 80% of the brain's blood supply. The vertebrobasilar system includes the vertebral arteries which join to form the basilar artery and provides the remaining 20% of blood supply. These two systems anastomose to form the cerebral arterial circle, also known as the Circle of Willis, at the base of the brain.
The spinal cord receives its blood supply from the anterior and posterior spinal arteries as well as radicular arteries. Venous drainage occurs through six irregular plexiform channels along the midlines and roots that drain into the epidural venous plexus and Batson's plexus, which may transport tumor cells. The anterior spinal artery arises from the vertebral artery and supplies the anterior two-thirds of the cord. Posterior spinal arteries from the vertebra arteries supply the posterior horns and dorsal funiculi. Radicular arteries from the intercostal arteries supply peripheral areas and anastomose with the anterior and posterior spinal arteries.
The document discusses cerebral circulation and the blood supply to the brain. It covers the functional anatomy of cerebral blood vessels including the internal carotid arteries and vertebral arteries which form the Circle of Willis. It also discusses the unique properties of brain capillaries and the blood-brain barrier. Measurement techniques for cerebral blood flow like Kety's method and radioactive methods are explained. Factors regulating cerebral blood flow including cerebral perfusion pressure, cerebral vascular resistance, and autoregulation are outlined. Finally, some applied aspects like stroke are briefly covered.
The document summarizes the development, anatomy, and histology of the pons and midbrain. It describes that the pons develops from the metencephalon and receives cells from the myelencephalon. The midbrain develops from the mesencephalon. The document then provides detailed descriptions of the structures, tracts, nuclei, and blood supply of both the pons and midbrain through multiple sections and diagrams.
The thoracic aorta begins where the aortic arch ends at the fourth thoracic vertebrae and extends down to the diaphragm. It supplies blood to the thoracic cavity and has several important branches including the bronchial arteries which supply the lungs, esophageal arteries which supply the esophagus, and posterior intercostal arteries which supply the spaces between the ribs. The thoracic aorta also gives off mediastinal and pericardial branches before passing through the diaphragm and becoming the abdominal aorta.
This document discusses the anatomy and physiology of cutaneous blood flow regulation. It notes that cutaneous blood flow at rest is 10-15 ml/min/100g of skin, falling to 1 ml/min/100g with cold exposure and increasing tenfold with heat exposure. Blood flow is primarily regulated by the sympathetic nervous system. Exposure to heat causes arteriole dilation, cutaneous vessel dilation, sweating, and bradykinin-induced dilation. Exposure to cold triggers vasoconstriction. Various reflexes and cortical mechanisms also influence blood flow regulation and skin color changes.
The brain stem is located between the cerebrum and spinal cord, and consists of the midbrain, pons, and medulla oblongata. The midbrain connects the forebrain to the pons and cerebellum. It contains important centers for visual and auditory reflexes, and gives rise to the trochlear nerve. Key structures in the midbrain include the superior and inferior colliculi, oculomotor nucleus, red nucleus, and substantia nigra. The midbrain serves to relay motor and sensory signals between the spinal cord and forebrain.
The cerebrospinal fluid (CSF) provides mechanical, chemical, and circulatory protection to the brain and spinal cord. It is formed by the choroid plexuses in the ventricles at a rate of around 550 ml per day, circulates through the ventricles and subarachnoid space, and is absorbed by arachnoid villi into venous sinuses. Disorders like hydrocephalus can occur if CSF circulation is obstructed or production/absorption is abnormal. Lumbar puncture and cisternal puncture are used to collect CSF samples or administer drugs into the CSF pathways.
The document provides an overview of the anatomy of the heart and surrounding structures. It describes the location of the heart in the chest and its internal and external structures. These include the four chambers of the heart (right and left atria and ventricles), major blood vessels (veins and arteries), surrounding membranes (pericardium), and other anatomical details.
The document discusses the arterial blood supply and venous drainage of the heart. It notes that the heart receives its blood supply from two coronary arteries - the right and left coronary arteries. These arteries branch further to supply different regions of the heart. The venous drainage occurs primarily via the coronary sinus, which drains into the right atrium. A few small veins also drain directly into the right atrium. The document outlines the branches and territories supplied by the right and left coronary arteries in detail.
The document discusses the anatomy and functions of the cerebellum. It begins by outlining the embryonic development and subdivision of the nervous system. It then describes the three functionally distinct regions of the cerebellum - the vestibulocerebellum, spinocerebellum, and cerebrocerebellum - and their different inputs and outputs. The document also discusses the cerebellar peduncles, cortex, and nuclei. It outlines the roles of the cerebellum in motor control and coordination and describes clinical signs of cerebellar dysfunction such as ataxia.
Cerebral circulation physiology by zainab iqbalArsalmushtaq7
This document discusses the cerebral circulation and blood supply to the brain. It describes how oxygenated blood is carried to the brain through the internal carotid and vertebral arteries, which unite to form the circle of Willis that gives rise to six cerebral arteries. These arteries supply blood to the brain. The document also notes that cerebral blood flow is normally 750mL/min and accounts for 50% of cardiac output. Additionally, it explains the role of the blood-brain barrier in protecting the brain by regulating the passage of molecules, cells and particles between the blood and cerebral spinal fluid.
This document provides an overview of the nervous system with a focus on the spinal cord. It discusses the anatomy and functions of the spinal cord, including its meninges, cross section, nuclei, tracts, nerves, and plexuses. It also covers spinal cord injuries and the Unani concept of the spinal cord from early Islamic physicians. In summary, the document outlines the key components and functions of the spinal cord, describes its internal structures and surrounding protective layers, and discusses spinal nerve roots and plexuses as well as historic Unani perspectives.
This document discusses the normal anatomy and development of the superior and inferior vena cavae as well as common congenital anomalies that can occur. It begins with a description of the typical anatomy of the superior and inferior vena cavae and their tributaries. It then explains the embryonic development of the major veins, including how the cardinal veins form and remodel into the adult venous structures. Finally, it outlines several important congenital anomalies including bilateral superior vena cavae, left-sided superior vena cava, retroaortic innominate vein, left inferior vena cava, azygos continuation of the inferior vena cava, and circumcaval anomalies. Recognition of these anomalies is important to
The document summarizes the cerebral blood supply system. It describes that the brain receives blood from two main arterial systems - the internal carotid and vertebral arteries. These arteries are connected via the circle of Willis, which allows for collateral blood flow if one artery is blocked. It then proceeds to describe each of the major arteries in detail, including their branches and the brain regions they supply.
The aorta is the main artery that carries oxygenated blood from the heart. It has four parts: ascending aorta, arch of aorta, descending thoracic aorta, and abdominal aorta. The ascending aorta leaves the heart and becomes the arch of the aorta behind the sternum. The arch of the aorta has branches for the head and arms before becoming the descending aorta in the chest. The descending aorta continues down and becomes the abdominal aorta, which has branches throughout the abdomen. The brachiocephalic veins join to form the superior vena cava, which carries blood from the head and arms to the heart. The inferior vena cava carries blood from the lower body to
Blood supply of the brain, neuro anatomy .Faarah Yusuf
The two main arteries supplying the brain are the internal carotid arteries and vertebral arteries. Within the skull, these arteries and their branches form a circle of connected blood vessels called the Circle of Willis. The Circle of Willis supplies different regions of the brain and helps ensure adequate blood flow if one artery is blocked. Strokes occur when blood flow to the brain is disrupted, such as from a blood clot blocking an artery.
Cerebellum by dr.gourav thakre 20 03-2012Gourav Thakre
This document provides an overview of the cerebellum, including its external features, subdivisions, cytoarchitecture, connections, circuitry, development, blood supply, and functions. Key points include:
- The cerebellum is located in the posterior cranial fossa and is divided into hemispheres, vermis, and lobes.
- It contains three layers - molecular, Purkinje cell, and granular layers. Purkinje cells are the sole output.
- Afferents include mossy and climbing fibers from the spinal cord, brainstem, and cortex. Efferents project to brainstem and thalamus.
- Functions include maintenance of posture and coordination of voluntary movement. It is involved
1. The document describes the venous drainage of the brain, which occurs through intracranial dural venous sinuses and internal jugular veins in the neck.
2. It outlines the characteristic features of brain venous drainage, including that it does not have an arterial pattern, the veins have extremely thin walls without muscular tissue, and they do not have valves.
3. The document then provides details on the different groups of cerebral veins that drain the surface of the brain hemispheres and their connections to various dural venous sinuses.
The document summarizes cardiac innervation by the autonomic nervous system. It notes that the sympathetic and parasympathetic nervous systems both originate in the medulla oblongata and spinal cord. The sympathetic system uses long preganglionic and postganglionic fibers that travel to cardiac ganglia before innervating the heart. In contrast, the parasympathetic system uses short preganglionic and postganglionic fibers to directly innervate the heart. The sympathetic system releases norepinephrine to increase heart rate and force of contraction, while the parasympathetic system releases acetylcholine to decrease heart rate.
1. Renal blood flow is tightly regulated to maintain a constant rate of around 1200 mL/min despite wide changes in blood pressure, through mechanisms like autoregulation and tubuloglomerular feedback.
2. The kidneys receive a high blood flow of around 20-30% of cardiac output despite their small size, and oxygen consumption in the kidneys is very high, second only to the heart.
3. Blood enters the kidneys through the renal artery and is distributed through a branching network of arteries before entering the glomerular capillaries and surrounding the nephron tubules, with the renal veins collecting the blood and returning it to circulation.
This document summarizes the anatomy of the circle of Willis and cerebral blood supply. It describes the circle of Willis as a polygonal anastomotic channel at the base of the brain supplied by the internal carotid and vertebral arteries. It then discusses the branches and functions of the circle of Willis, cortical and central arteries, lenticulostriate arteries, and the blood-brain barrier. Finally, it provides details on the regional arterial supply of different brain regions and applied anatomy related to various neurological syndromes.
The cerebral circulation supplies blood to the brain through arteries like the internal carotid and vertebral arteries. Blood flow is regulated by factors like carbon dioxide, oxygen, and chemicals released by astrocytes. Cerebrospinal fluid is produced in the brain ventricles at a rate of 500 mL per day and circulates through the subarachnoid space, cushioning the brain. Abnormal CSF pressure can cause issues like hydrocephalus or papilledema, and may be treated with shunts or lumbar punctures.
The cerebellum and basal ganglia play important roles in motor control and coordination. The cerebellum helps control the timing, smoothness, and intensity of muscle movements. It receives sensory feedback and compares actual movements to planned movements, sending corrections back to the motor system. The basal ganglia help plan and control complex patterns of muscle movement. The cerebellum has distinct input and output pathways and its Purkinje cells provide inhibitory signals that help regulate the output of deep nuclear cells and coordinate movement.
The document summarizes blood circulation to the brain. It describes how blood is supplied to the brain through two internal carotid arteries and two vertebral arteries that form a complex network called the circle of Willis. It then discusses the major arteries that branch off from this circle - the anterior, middle, and posterior cerebral arteries - and the regions of the brain each supplies. It notes that decreases in blood flow through these arteries can cause impairments or weaknesses on the opposite side of the body.
The blood supply of the brain and spinal cordMelad Bassim
The document summarizes the blood supply of the brain and spinal cord. It describes that the brain receives blood from the internal carotid and vertebral arteries, which form the circle of Willis. It then discusses the specific branches and territories supplied by the internal carotid, vertebral, and basilar arteries. It also summarizes the veins that drain the brain and the arteries that supply blood to the spinal cord. Finally, it briefly describes clinical syndromes that can result from occlusions of the main cerebral arteries.
The brain receives its blood supply from two internal carotid arteries and two vertebral arteries. These vessels anastomose to form the circle of Willis at the base of the brain. The internal carotid artery gives off branches that supply the anterior circulation, including the anterior cerebral artery and middle cerebral artery. The vertebral arteries join to form the basilar artery, which supplies the posterior circulation via branches such as the posterior cerebral artery. Various arteries anastomose to provide collateral circulation. Venous drainage involves superficial and deep veins that drain primarily into the dural venous sinuses.
The document summarizes the arterial blood supply and venous drainage of the brain and spinal cord. It describes the two main arterial systems - the internal carotid and vertebral arteries - and how they anastomose to form the Circle of Willis. It details the branches and territories supplied by the major cerebral and spinal arteries. It also outlines the internal and external cerebral veins that drain the brain into the dural venous sinuses, and the internal and external vertebral venous plexuses that drain the spinal cord.
لقطة شاشة ٢٠٢٣-١١-١٢ في ١١.٤٥.٤٨ ص.pdfahmad2100799
The document summarizes the vascularization of the brain. There are two main arterial circuits that supply the brain - the anterior circulation supplied by the internal carotid arteries, and the posterior circulation supplied by the vertebrobasilar system. These arteries anastomose to form the Circle of Willis at the base of the brain. The anterior circulation includes the internal carotid arteries, anterior cerebral arteries, anterior communicating artery, and middle cerebral arteries. The posterior circulation is supplied by the vertebral arteries, basilar artery, posterior cerebral arteries, and posterior communicating arteries.
The document provides an overview of the anatomy of the heart and surrounding structures. It describes the location of the heart in the chest and its internal and external structures. These include the four chambers of the heart (right and left atria and ventricles), major blood vessels (veins and arteries), surrounding membranes (pericardium), and other anatomical details.
The document discusses the arterial blood supply and venous drainage of the heart. It notes that the heart receives its blood supply from two coronary arteries - the right and left coronary arteries. These arteries branch further to supply different regions of the heart. The venous drainage occurs primarily via the coronary sinus, which drains into the right atrium. A few small veins also drain directly into the right atrium. The document outlines the branches and territories supplied by the right and left coronary arteries in detail.
The document discusses the anatomy and functions of the cerebellum. It begins by outlining the embryonic development and subdivision of the nervous system. It then describes the three functionally distinct regions of the cerebellum - the vestibulocerebellum, spinocerebellum, and cerebrocerebellum - and their different inputs and outputs. The document also discusses the cerebellar peduncles, cortex, and nuclei. It outlines the roles of the cerebellum in motor control and coordination and describes clinical signs of cerebellar dysfunction such as ataxia.
Cerebral circulation physiology by zainab iqbalArsalmushtaq7
This document discusses the cerebral circulation and blood supply to the brain. It describes how oxygenated blood is carried to the brain through the internal carotid and vertebral arteries, which unite to form the circle of Willis that gives rise to six cerebral arteries. These arteries supply blood to the brain. The document also notes that cerebral blood flow is normally 750mL/min and accounts for 50% of cardiac output. Additionally, it explains the role of the blood-brain barrier in protecting the brain by regulating the passage of molecules, cells and particles between the blood and cerebral spinal fluid.
This document provides an overview of the nervous system with a focus on the spinal cord. It discusses the anatomy and functions of the spinal cord, including its meninges, cross section, nuclei, tracts, nerves, and plexuses. It also covers spinal cord injuries and the Unani concept of the spinal cord from early Islamic physicians. In summary, the document outlines the key components and functions of the spinal cord, describes its internal structures and surrounding protective layers, and discusses spinal nerve roots and plexuses as well as historic Unani perspectives.
This document discusses the normal anatomy and development of the superior and inferior vena cavae as well as common congenital anomalies that can occur. It begins with a description of the typical anatomy of the superior and inferior vena cavae and their tributaries. It then explains the embryonic development of the major veins, including how the cardinal veins form and remodel into the adult venous structures. Finally, it outlines several important congenital anomalies including bilateral superior vena cavae, left-sided superior vena cava, retroaortic innominate vein, left inferior vena cava, azygos continuation of the inferior vena cava, and circumcaval anomalies. Recognition of these anomalies is important to
The document summarizes the cerebral blood supply system. It describes that the brain receives blood from two main arterial systems - the internal carotid and vertebral arteries. These arteries are connected via the circle of Willis, which allows for collateral blood flow if one artery is blocked. It then proceeds to describe each of the major arteries in detail, including their branches and the brain regions they supply.
The aorta is the main artery that carries oxygenated blood from the heart. It has four parts: ascending aorta, arch of aorta, descending thoracic aorta, and abdominal aorta. The ascending aorta leaves the heart and becomes the arch of the aorta behind the sternum. The arch of the aorta has branches for the head and arms before becoming the descending aorta in the chest. The descending aorta continues down and becomes the abdominal aorta, which has branches throughout the abdomen. The brachiocephalic veins join to form the superior vena cava, which carries blood from the head and arms to the heart. The inferior vena cava carries blood from the lower body to
Blood supply of the brain, neuro anatomy .Faarah Yusuf
The two main arteries supplying the brain are the internal carotid arteries and vertebral arteries. Within the skull, these arteries and their branches form a circle of connected blood vessels called the Circle of Willis. The Circle of Willis supplies different regions of the brain and helps ensure adequate blood flow if one artery is blocked. Strokes occur when blood flow to the brain is disrupted, such as from a blood clot blocking an artery.
Cerebellum by dr.gourav thakre 20 03-2012Gourav Thakre
This document provides an overview of the cerebellum, including its external features, subdivisions, cytoarchitecture, connections, circuitry, development, blood supply, and functions. Key points include:
- The cerebellum is located in the posterior cranial fossa and is divided into hemispheres, vermis, and lobes.
- It contains three layers - molecular, Purkinje cell, and granular layers. Purkinje cells are the sole output.
- Afferents include mossy and climbing fibers from the spinal cord, brainstem, and cortex. Efferents project to brainstem and thalamus.
- Functions include maintenance of posture and coordination of voluntary movement. It is involved
1. The document describes the venous drainage of the brain, which occurs through intracranial dural venous sinuses and internal jugular veins in the neck.
2. It outlines the characteristic features of brain venous drainage, including that it does not have an arterial pattern, the veins have extremely thin walls without muscular tissue, and they do not have valves.
3. The document then provides details on the different groups of cerebral veins that drain the surface of the brain hemispheres and their connections to various dural venous sinuses.
The document summarizes cardiac innervation by the autonomic nervous system. It notes that the sympathetic and parasympathetic nervous systems both originate in the medulla oblongata and spinal cord. The sympathetic system uses long preganglionic and postganglionic fibers that travel to cardiac ganglia before innervating the heart. In contrast, the parasympathetic system uses short preganglionic and postganglionic fibers to directly innervate the heart. The sympathetic system releases norepinephrine to increase heart rate and force of contraction, while the parasympathetic system releases acetylcholine to decrease heart rate.
1. Renal blood flow is tightly regulated to maintain a constant rate of around 1200 mL/min despite wide changes in blood pressure, through mechanisms like autoregulation and tubuloglomerular feedback.
2. The kidneys receive a high blood flow of around 20-30% of cardiac output despite their small size, and oxygen consumption in the kidneys is very high, second only to the heart.
3. Blood enters the kidneys through the renal artery and is distributed through a branching network of arteries before entering the glomerular capillaries and surrounding the nephron tubules, with the renal veins collecting the blood and returning it to circulation.
This document summarizes the anatomy of the circle of Willis and cerebral blood supply. It describes the circle of Willis as a polygonal anastomotic channel at the base of the brain supplied by the internal carotid and vertebral arteries. It then discusses the branches and functions of the circle of Willis, cortical and central arteries, lenticulostriate arteries, and the blood-brain barrier. Finally, it provides details on the regional arterial supply of different brain regions and applied anatomy related to various neurological syndromes.
The cerebral circulation supplies blood to the brain through arteries like the internal carotid and vertebral arteries. Blood flow is regulated by factors like carbon dioxide, oxygen, and chemicals released by astrocytes. Cerebrospinal fluid is produced in the brain ventricles at a rate of 500 mL per day and circulates through the subarachnoid space, cushioning the brain. Abnormal CSF pressure can cause issues like hydrocephalus or papilledema, and may be treated with shunts or lumbar punctures.
The cerebellum and basal ganglia play important roles in motor control and coordination. The cerebellum helps control the timing, smoothness, and intensity of muscle movements. It receives sensory feedback and compares actual movements to planned movements, sending corrections back to the motor system. The basal ganglia help plan and control complex patterns of muscle movement. The cerebellum has distinct input and output pathways and its Purkinje cells provide inhibitory signals that help regulate the output of deep nuclear cells and coordinate movement.
The document summarizes blood circulation to the brain. It describes how blood is supplied to the brain through two internal carotid arteries and two vertebral arteries that form a complex network called the circle of Willis. It then discusses the major arteries that branch off from this circle - the anterior, middle, and posterior cerebral arteries - and the regions of the brain each supplies. It notes that decreases in blood flow through these arteries can cause impairments or weaknesses on the opposite side of the body.
The blood supply of the brain and spinal cordMelad Bassim
The document summarizes the blood supply of the brain and spinal cord. It describes that the brain receives blood from the internal carotid and vertebral arteries, which form the circle of Willis. It then discusses the specific branches and territories supplied by the internal carotid, vertebral, and basilar arteries. It also summarizes the veins that drain the brain and the arteries that supply blood to the spinal cord. Finally, it briefly describes clinical syndromes that can result from occlusions of the main cerebral arteries.
The brain receives its blood supply from two internal carotid arteries and two vertebral arteries. These vessels anastomose to form the circle of Willis at the base of the brain. The internal carotid artery gives off branches that supply the anterior circulation, including the anterior cerebral artery and middle cerebral artery. The vertebral arteries join to form the basilar artery, which supplies the posterior circulation via branches such as the posterior cerebral artery. Various arteries anastomose to provide collateral circulation. Venous drainage involves superficial and deep veins that drain primarily into the dural venous sinuses.
The document summarizes the arterial blood supply and venous drainage of the brain and spinal cord. It describes the two main arterial systems - the internal carotid and vertebral arteries - and how they anastomose to form the Circle of Willis. It details the branches and territories supplied by the major cerebral and spinal arteries. It also outlines the internal and external cerebral veins that drain the brain into the dural venous sinuses, and the internal and external vertebral venous plexuses that drain the spinal cord.
لقطة شاشة ٢٠٢٣-١١-١٢ في ١١.٤٥.٤٨ ص.pdfahmad2100799
The document summarizes the vascularization of the brain. There are two main arterial circuits that supply the brain - the anterior circulation supplied by the internal carotid arteries, and the posterior circulation supplied by the vertebrobasilar system. These arteries anastomose to form the Circle of Willis at the base of the brain. The anterior circulation includes the internal carotid arteries, anterior cerebral arteries, anterior communicating artery, and middle cerebral arteries. The posterior circulation is supplied by the vertebral arteries, basilar artery, posterior cerebral arteries, and posterior communicating arteries.
The nervous system receives its blood supply from arteries that branch throughout the brain and spinal cord. The brain is supplied by the internal carotid and vertebral arteries, which form the circle of Willis at the base of the brain. These arteries further branch to supply specific regions like the cerebrum, cerebellum, and brainstem. The spinal cord receives blood from the anterior and posterior spinal arteries as well as segmental arteries that enter through vertebral foramina. Veins drain blood from the brain and spinal cord into dural sinuses and internal vertebral plexuses.
The brain receives its blood supply from two paired arteries - the vertebral arteries and internal carotid arteries. These arteries and their branches anastomose to form the Circle of Willis, which ensures adequate blood flow to the brain. Deoxygenated blood from the brain drains into dural venous sinuses that eventually empty into the internal jugular veins.
This document summarizes the arterial supply and venous drainage of the brain and spinal cord. It discusses how the brain receives blood from the internal carotid and vertebral arteries, which connect at the circle of Willis to provide an interconnected blood supply. It describes the branches of these arteries and their territories. It also outlines the venous drainage pathways and discusses the blood-brain barrier. For the spinal cord, it explains that the anterior and posterior spinal arteries are the main arterial supply, along with segmental arteries.
The document discusses the anatomy and blood supply of the brain. It describes that the brain receives blood supply from two main systems - the carotid system and vertebrobasilar system. The carotid system provides 70% of the blood supply while the vertebrobasilar system provides the remaining 30%. It also discusses the key arteries like the internal carotid, vertebral, basilar and cerebral arteries along with their branches that supply different regions of the brain.
The document discusses the major blood vessels of the systemic circulation, including arteries branching from the aorta such as the brachiocephalic, common carotid, and subclavian arteries. It then describes arteries supplying specific regions like the head, neck, upper limbs, brain, and thorax. The aorta gives rise to visceral arteries to thoracic organs and parietal arteries to the thoracic wall including intercostal arteries.
The brain and spinal cord receive blood from several major arteries. The brain is supplied by the internal carotid arteries in the neck and the vertebral arteries in the neck, which join to form the circle of Willis at the base of the brain. From this circle branches the anterior, middle, and posterior cerebral arteries which divide further to supply different regions of the brain. The spinal cord receives blood mainly from the anterior and posterior spinal arteries which branch from the vertebral arteries in the neck.
The document discusses the arterial supply of the brain and spinal cord. It begins by outlining the two main sources of arterial blood supply to the brain - the internal carotid arteries and the vertebral arteries. It describes how these vessels form an arterial ring at the base of the brain called the Circle of Willis. The document then discusses the specific branches arising from these arteries and their blood supply territories in the brain and spinal cord. It concludes by mentioning some clinical implications such as stroke and hemorrhages that can result from disruptions to this arterial circulation.
The document summarizes the arterial blood supply and venous drainage of the brain. It discusses the two main sources of arterial blood - the internal carotid and vertebral arteries. It describes the branches of these arteries and their territories. It also discusses the clinical consequences of occlusions in different arteries. The circle of Willis and venous drainage routes are also summarized.
Blood supply of the brain & spinal cord by dr sarwarporag sarwar
The document summarizes the blood supply of the brain and spinal cord. There are two main systems - the carotid system supplying 80% and the vertebrobasilar system supplying 20%. The vertebrobasilar system supplies the brainstem, cerebellum and parts of the diencephalon and telencephalon. It is formed from the two vertebral arteries joining to form the basilar artery. The basilar artery then gives off branches including the posterior cerebral arteries. The carotid system arises from the internal and external carotid arteries. The internal carotid artery gives off branches including the anterior and middle cerebral arteries. These arteries anastomose to form the circle of Willis at the base of the brain.
The veins of the brain can be divided into superficial and deep veins. Superficial veins drain the outer structures of the brain while deep veins drain the inner structures. Major veins include the superior and inferior cerebral veins, superficial middle cerebral veins, great cerebral vein, internal cerebral veins, and superior and inferior cerebellar veins. These veins drain into dural venous sinuses, which then drain into the internal jugular veins. The unique venous drainage system of the brain differs from other body regions where venous drainage typically follows arterial supply.
The brain receives its arterial blood supply from two internal carotid arteries and two vertebral arteries. These vessels form an anastomosis called the circle of Willis at the base of the brain. The internal carotid arteries supply the anterior circulation to most of the forebrain, while the vertebral arteries contribute to the posterior or vertebrobasilar circulation to the brainstem and cerebellum. Disruption of blood flow to the brain for more than a few minutes can cause permanent neurological damage through ischemic strokes or hemorrhages such as those from aneurysms.
The document discusses the major arteries of the neck including the common carotid artery, internal carotid artery, external carotid artery, vertebral artery, and brachiocephalic artery. The common carotid artery divides into the internal and external carotid arteries. The internal carotid artery supplies the brain, while the external carotid artery supplies the face and neck. The vertebral arteries originate from the subclavian arteries and supply the spinal cord, brainstem, cerebellum, and back of the brain. The brachiocephalic artery is the first branch of the aortic arch and divides into the right common carotid and right subclavian arteries.
The document discusses the vascularization of the brain. It covers the arterial supply from the internal carotid and vertebral arteries which anastomose to form the circle of Willis, ensuring a dual blood supply. It also discusses the venous drainage via the dural sinuses and internal jugular veins. Finally, it covers the choroid plexus and circulation of cerebrospinal fluid, which is produced at a rate of 500mL per day to provide cushioning and protection to the brain.
The document discusses the arterial supply of the brain. It describes the major arteries - the vertebral arteries, basilar artery, internal carotid arteries, anterior cerebral artery, middle cerebral artery, and posterior cerebral artery. These arteries form anastomoses around the circle of Willis at the base of the brain to provide a continuous blood supply to the brain through both the carotid and vertebral systems. Disruptions to this arterial network can impair blood flow and oxygen delivery to the brain.
The brain and spinal cord are protected and cushioned by three layers of tissue (the meninges) and cerebrospinal fluid. The meninges include the dura mater, arachnoid mater, and pia mater. Cerebrospinal fluid is produced by the choroid plexus within the ventricles and circulates around the brain and spinal cord. Blood enters the brain through the internal carotid and vertebral arteries, and drains into venous sinuses which form the jugular veins. The blood brain barrier regulates what substances can enter the brain by restricting passage through tight junctions between endothelial cells.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
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Anatomy and physiology of cerebral circulation and csf
1. ANATOMY AND
PHYSIOLOGY OF
CEREBRAL CIRCULATION
AND CSF.
NAME OF THE TEACHER NAME OF THE STUDENT
Dr.(Ms) Sucheta Yangad Miss Seri Lollen
Associate professor MSc.(N) 1st year
Dr. DYCON , PUNE Dr. DYCON,PUNE
2. The brain :-
The brain is contained in skull & weighs 1300-1400 g
Made up of about 1000 billion neurons, 7 each neuron is surrounded by about
10 glial cells (neuroglia).
Brain is also covered by "Meninges" like spinal cord ,outer duramater, middle
arachnoid mater & inner piamater.
It is one of the largest organs in the body, and coordinates most body activities.
It is the center for all thought, memory, judgment, and emotion.
Each part of the brain is responsible for controlling different body functions,
such as temperature regulation and breathing.
4. Ventricles of the brain
There are certain cavities in the brain
called as "ventricles"
These ventricles are filled with CSF.
There are 4 ventricles of brain:-
1) 2 lateral ventricles in two hemisphere of
the brain
2) 3 lies between hypothalamus & thalamus
3) 4th between brain stem & cerebellum
& is continuous with the central cavity of
spinal cord
5. Parts of brain
Cerebrum Cerebellum Brain steam Diencephelon
1)Right cerebral 1) Medulla 1)Thalamus
hemisphere 2) Pons 2)hypothalamus
2) Left cerebral
hemisphere 3)Mid brain 3)Epithalamus&
pineal gland
6. CEREBRAL CIRCULATION :-
Cerebral circulation is the movement of blood through the network
of blood vessels to supply the brain.
The arteries carry oxygenated blood and other nutrients to the brain.
The veins carry deoxygenated blood back to the heart removing
carbon dioxide and other metabolic products.
The movement of blood in the cerebral circulation is called cerebral
blood flow.
7. Blood supply
Blood supply to the brain is normally divided into anterior and posterior
segments.
The two main pairs of arteries are :-
1)The Internal carotid arteries (supply the anterior brain)
2) Vertebral arteries (supplying the brainstem and posterior brain).
8. The anterior and posterior cerebral circulations are
interconnected via bilateral posterior
communicating arteries.
They are part of the Circle of Willis, which
provides backup circulation to the brain.
9. 1)Anterior cerebral circulation
The anterior cerebral circulation is the blood supply to the
anterior portion of the brain including eyes. It is supplied by
the following arteries:
The internal carotid artery is located in the inner side of the
neck in contrast to the external carotid artery. In human
anatomy, they arise from the common carotid arteries,
where these bifurcate into the internal and external carotid
arteries at cervical vertebral level 3 or 4; the internal carotid
artery supplies the brain, including the eyes, while the
external carotid nourishes other portions of the head, such
as the face, the scalp, the skull, and the meninges.
10. Anterior cerebral artery (ACA)
The anterior cerebral artery (ACA) is one of a pair of arteries on the brain that
supplies oxygenated blood to most midline portions of the frontal
lobes and superior medial parietal lobes. The two anterior cerebral arteries arise
from the internal carotid artery and are part of the circle of Willis. The left and right
anterior cerebral arteries are connected by the anterior communicating artery.
Medial surface of cerebral hemisphere, showing areas
supplied by cerebral arteries. blue
11. Anterior communicating artery:
The anterior communicating artery is a blood vessel of the brain that connects the left and
right anterior cerebral arteries. the two arteries joining together to form a single trunk, which afterward
divides.
Normally, the anterior communicating artery does not significantly contribute to cerebral blood
supply, as there is negligible net blood flow within it, and some of its anteromedial branches seem to
be specially adapted to ease forebrain sodium sensing, rather than to supply the brain with blood.
12. Middle cerebral artery
The middle cerebral artery (MCA) is one of the three major paired arteries that
supply blood to the cerebrum. The MCA arises from the internal carotid and continues into
the lateral sulcus where it then branches and projects to many parts of the lateral cerebral
cortex. It also supplies blood to the anterior temporal lobes and the insular cortices.
13. 2) Posterior cerebral circulation
The posterior cerebral circulation is the blood supply to the posterior
portion of the brain, including the occipital
lobes, cerebellum and brainstem. It is supplied by the following
arteries:-
Vertebral arteries:
These smaller arteries branch from the subclavian arteries which
primarily supply the shoulders, lateral chest, and arms. Within
the cranium the two vertebral arteries fuse into the basilar artery.
As the supplying component of the vertebrobasilar vascular
system, the vertebral arteries supply blood to the upper spinal
cord, brainstem, cerebellum, and posterior part of brain.
14. Posterior inferior cerebellar artery (PICA):
The posterior inferior cerebellar artery (PICA) is the largest branch
of the vertebral artery. It is one of the three main arteries that supply
blood to the cerebellum, a part of the brain.
Blockage of the posterior inferior cerebellar artery can result in a
type of stroke called lateral medullary syndrome.
Basilar artery:
Supplies the midbrain, cerebellum, and usually branches into
the posterior cerebral artery.
Anterior inferior cerebellar artery (AICA)
Is one of three pairs of arteries that supplies blood to
the cerebellum.
15. Pontine arteries
The pontine arteries are a number of small vessels which come off at right
angles from either side of the basilar artery and supply the pons and adjacent
parts of the brain.
Superior cerebellar artery (SCA)
The superior cerebellar artery (SCA) arises near the termination of
the basilar artery.
The artery supplies:
Superior half of the cerebellum
Parts of the midbrain
16. Posterior cerebral artery (PCA)
The posterior cerebral artery (PCA) is one of a pair of arteries that supply
oxygenated blood to the occipital lobe, part of the back of the human brain.
Posterior communicating artery
The left and right posterior communicating arteries are arteries at the base
of the brain that form part of the circle of Willis. Each posterior
communicating artery connects the three cerebral arteries of the same side.
Anteriorly, it connects to the internal carotid artery (ICA) prior to the
terminal bifurcation of the ICA into the anterior cerebral artery and middle
cerebral artery. Posteriorly, it communicates with the posterior cerebral
artery.
17. Circulus arteriosus (circle of Willis)
The greater part of the brain is supplied with arterial blood by an
arrangement of arteries called the circulus arteriosus or the circle of
Willis .
Four large arteries contribute to its formation: the two internal carotid
arteries and the two vertebral arteries .
The vertebral arteries arise from the subclavian arteries, pass upwards
through the foramina in the transverse processes of the cervical vertebrae,
enter the skull through the fora men magnum, then join to form the
basilar artery.
The arrangement in the circulus arteriosus is such that the brain as a
whole receives an adequate blood supply when a contributing artery is
damaged and during extreme movements of the head and neck.
Anteriorly, the two anterior cerebral arteries arise from the internal
carotid arteries and are joined by the anterior communicating artery.
18.
19.
20. Posteriorly, the two vertebral arteries join to form the basilar artery. After
travelling for a short distance the basilar artery divides to form two posterior
cerebral arteries, each of which is joined to the corresponding internal carotid
artery by a posterior communicating artery, completing the circle.
The circulus arteriosus is therefore formed by:
2 anterior cerebral arteries
2 internal carotid arteries
1 anterior communicating artery
2 posterior communicating arteries
2 posterior cerebral arteries
1 basilar artery.
From this circle, the anterior cerebral arteries pass forward to supply the
anterior part of the brain, the middle cerebral arteries pass laterally to supply the
sides of the brain, and the posterior cerebral arteries supply the posterior part of the
brain. Branches of the basilar artery supply parts of the brain.
21. venous drainage of brain:
The venous blood from the head is returned by deep and superficial veins.
Superficial veins with the same names as the branches of the external
carotid artery return venous blood from the superficial structures of the face
and scalp and unite to form the external jugular veins.
The external jugular vein beings in the neck at the level of the angle of the
jaw. It passes downwards in fornt of the sternocleidomastoid muscles , then
behind the clavicle before entering the subclavian vein.
The venous blood from the deep areas of the brain is collected into
channels called the dural venous sinuses.
The dural venous sinuses of the brain are formed by layers of the dura
matar lined with endothelium . the dura matar is the outer protective covering
of the brain .
22. The main venous sinuses are listed below:
1) The superine sagittal sinus carries the venous blood from the superior part of the brain,
It begins in the frontal region and passes directly backwards in the midline of the skull
to the occipital it turns to the right side and continue as the right transverse sinus.
2) The inferior sagittal sinus lies deep within the brain and passes backwards to form the
straight sinus
3) The straight sinus runs backwards and downwards to become the left transverse sinus.
4) The transverse sinuses begin in the occipital region. They run forward and medially in a
curved groove f the skull, to become continuous with the sigmoid sinuses.
5) The sigmoid sinuses are a continuation of the transverse sinuses. Each curves downward
and mediality and lies in a groove in the mastoid process of the temporal bone.
Anteriorly only a thin plate of bone separate the sinus from the air cells in the mastold
process of the temporal bone. Inferiorly it continues as the Internal jugular vein.
25. CEREBROSPINAL FLUID :
Introduction
CSF is clear, colorless and transparent circulates through cavity of the :-
-Brain
-Subarachnoid space
-Central canal of spinal cord
-Part of Extracellular fluid (ECF)
Definition :-
Cerebrospinal fluid (CSF) cushions the brain and along with blood-brain
barrier, the buffering function of neuroglia, and regulation of CNS circulation
controls extracellular environment of neurons. Within the substance of brain in
the ventricular system, there are series of spaces filled with CSF.
26.
27. Composition, Volume and pressure of CSF:-
Composition of CSF:-
The extracellular fluid within the CNS communicates directly with the CSF.
Thus, the composition of CSF indicates the composition of the extracellular
environment of the neurons in the brain and spinal cord.
The CSF differs from blood in having a lower concentration of K. glucose,
and protein and a higher concentration of Na' and C.
CSF normally lacks blood cells.
The increased concentration of Na' and Cl- enables the CSF to be isotonic to
blood, despite the much lower concentration of proteins in the CSF.
28. CEREBROSPINAL FLUID
Water -99.13%
Solids- 0.87%
Solid is divided into :-
1)Organic substances
Protein
Amino acids
Sugar
Urea
Uric acid creatinine
Lactic acid
2)Inorganic substances
Sodium
Calcium
Potassium
Magnesium
Sulfates
29. The total volume of human CSF is between
150 and 160 mL .
To maintain this volume, CSF secretion
and drainage must be equal; imbalances to
this equilibrium will produce an increase in
the total fluid content of the brain,
subsequently causing an elevation in
pressure.
30. PROPERTIES
Volume: approximately 150 mL
Rate of formation: approximately 0.3 mL/min
Specific gravity: 1.005
Reaction: Alkalin
Formation of CSF
Formed by the choroid plexus situated within the ventricles.
The choroid plexus are tuft of capillary projections present inside ventricles
and covered by:
Pia mater
Ependymal covering.
31. Substances affecting the formation of CSF
Pilocarpine, ether and extracts of pituitary gland stimulates the secretion of
CSF by stimulating choroid plexus.
Injection of isotonic saline also stimulates CSF formation.
Injection of hypotonic saline
-Causes greater rise in capillary pressure and intracranial
pressure,
-Fall in osmotic pressure leading to increase in CSF
formation.
Hypertonic saline
-Decreases CSF formation
-Decreases CSF pressure
32. Circulation of CSF
CSF formed in the lateral ventricles passes through the interventricular
foramina into the third ventricle. Thence the fluid flows trough the cerebral
aqueduct (of Sylvius) into the fourth ventricle. From fourth ventricle, some
CSF passes into the central canal of spinal cord, but most escapes into the
subarachnoid space (surrounding the brain and spinal cord) through the
median aperture (foramen of Magendie) of fourth ventricle and the two lateral
apertures of fourth ventricle (foramina of Luschka). Subarachnoid cistern
refers to the regions where subarachnoid space is distended to form pools of
CSF. An example as the lumbar cistern which surrounds the lumbar and sacral
spinal root belows the level of termination of spinal cord. The lumber cistern is
the targeted for lumber puncture. A procedure used clinically to sample the csf.
33.
34. Absorption of CSF
Mostly absorbed by the Arachnoid villi into Dural sinuses and Spinal veins.
Small amount is absorbed along the perineural spaces into cervical
lymphatics and in to the perivascular spaces.
Normally, 500 mL of CF is formed everyday and equal amount is absorbed.
Functions of CSF .
Protection to CNS by acting as water-jacket, as it absorbs shock in the
event of blow .
Removal of Waste products of brain metabolism.
Regulates extracellular environment for the neurons of central nervous
system.
Transports hormones and hormone-releasing factors.
35. BLOOD -CSF BARRIER
The capillaries that travers the choroidal plexuses are freely permeable
to plasma solutes. However , a barrier exists at the level of epithelial calls
that make up the choroid plexuses. This barrier is responsible for carrier
mediated active transport.