This document summarizes an animal study testing new dental and orthopedic implant materials. It discusses the motivation for animal testing prior to human clinical trials. It describes the materials to be tested - dense alumina-zirconia composites. Small animal models (Wistar rats) and larger animal models (rabbits) are proposed. The surgical procedures, monitoring, and analysis methods are outlined, including radiography, histology, and SEM/EDX to examine the bone-implant interface. Preliminary conclusions suggest the materials show good biocompatibility in animals and that surface coatings could improve biological response. The study involves collaboration between universities in Romania and Turkey.