Warfarin is a medication used to treat and prevent blood clots. It comes as a 5mg white tablet and can cause bleeding from the nose, urine, stomach, gums, or cuts. Maintaining a stable vitamin K intake and avoiding alcohol and other drugs without consulting a doctor is important when taking warfarin. The dosage is based on PT/INR levels and should be taken at the same time each day as prescribed to effectively thin the blood. Patients should carry an identification card noting they are on warfarin and see their doctor regularly for monitoring.
Warfarin. Most used oral anticoagulant in the world. In some cases it has no alternative. Has many side effects. Careful monitoring and judicious titration of dose can make it best. Live long Warfarin.
Drug Interactions of ADP receptor Blockers (Antiplatelets)Naina Mohamed, PhD
· ADP receptor Blockers (Antiplatelets) include Thienopyridines (Clopidogrel, Prasugrel, Ticlopidine) and Non-Thienopyridines (Ticagrelor, Cangrelor, Elinogrel ).
· The risk of adverse effects could be reduced by healthcare professionals through the screening, education, and follow up on suspected drug interactions.
Warfarin. Most used oral anticoagulant in the world. In some cases it has no alternative. Has many side effects. Careful monitoring and judicious titration of dose can make it best. Live long Warfarin.
Drug Interactions of ADP receptor Blockers (Antiplatelets)Naina Mohamed, PhD
· ADP receptor Blockers (Antiplatelets) include Thienopyridines (Clopidogrel, Prasugrel, Ticlopidine) and Non-Thienopyridines (Ticagrelor, Cangrelor, Elinogrel ).
· The risk of adverse effects could be reduced by healthcare professionals through the screening, education, and follow up on suspected drug interactions.
Digoxin & Nitroglycerin by Dr. Sanaullah Aslam (Complete)Sanaullah Aslam
Your Feedback will be highly appreciated. This presentation was made for students at pharmacy institute in a project of clinical pharmacy and use of digoxin and nitroglycerin. This presentation is made so that you can present it in a same session, without any change.
Author: Danielle Cassidy, Pharm.D., BCPS
Description: Educational handout created for families and young adults discharged from the hospital on warfarin therapy.
Digoxin & Nitroglycerin by Dr. Sanaullah Aslam (Complete)Sanaullah Aslam
Your Feedback will be highly appreciated. This presentation was made for students at pharmacy institute in a project of clinical pharmacy and use of digoxin and nitroglycerin. This presentation is made so that you can present it in a same session, without any change.
Author: Danielle Cassidy, Pharm.D., BCPS
Description: Educational handout created for families and young adults discharged from the hospital on warfarin therapy.
Generic Pirfenidone Tablets (Pirfenex by Cipla) is an antifibrotic agent which is used to treat mild to moderate forms of a certain lung disease called Idiopathic Pulmonary Fibrosis (IPF). This disease causes the lungs to get scarred and become stiff, making it difficult to breathe.
Buy Femilon Tablet (Drospirenone 0.15 Mg & Ethinylestradiol 0.02 Mg), Ethinyl estradiol and Drospirenone also sold under the brand name Yaz is a birth control pill. It works by preventing ovulation or the release of a female egg from the ovaries.
Buy XBIRA 250 mg (Abiraterone Acetate 250 mg) may cause hypertension [high blood pressure], hypokalemia [low levels of potassium in the blood], and fluid retention.
Vidalista (Generic Tadalafil Tablets) is an oral medicine that is used for treating impotence (the inability to attain or maintain a penile erection). You can choose to take it on an as needed basis or take a low dose version everyday, so that you can be ready anytime.
Multivitamin capsules smpc taj pharmaceuticalsTaj Pharma
MULTIVITAMIN CAPSULES Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, MULTIVITAMIN CAPSULES Dosage & Rx Info | MULTIVITAMIN CAPSULES Uses, Side Effects -: Indications, Side Effects, Warnings, MULTIVITAMIN CAPSULES - Drug Information - Taj Pharma, MULTIVITAMIN CAPSULES dose Taj pharmaceuticals MULTIVITAMIN CAPSULES interactions, Taj Pharmaceutical MULTIVITAMIN CAPSULES contraindications, MULTIVITAMIN CAPSULES price, MULTIVITAMIN CAPSULES Taj Pharma MULTIVITAMIN CAPSULES SMPC- Taj Pharma . Stay connected to all updated on MULTIVITAMIN CAPSULES Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Paliperidone 3mg/6mg/9mg/12mg Extended-release Tablets Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Paliperidone Dosage & Rx Info | Paliperidone Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Paliperidone-Drug Information –Taj Pharma, Paliperidone dose Taj pharmaceuticals Paliperidone interactions, Taj Pharmaceutical Paliperidone contraindications, Paliperidone price, Paliperidone Taj Pharma Paliperidone SmPC-Taj Pharma Stay connected to all updated on Paliperidone Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
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Ifosfamide for Injection USP 100mg, 500mg, 1000mg, and 2000mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Ifosfamide Dosage & Rx Info | Ifosfamide Uses, Side Effects Ifosfamide: Indications, Side Effects, Warnings, Ifosfamide -Drug Information –Taj Pharma, Ifosfamide dose Taj pharmaceuticals Ifosfamide interactions, Taj Pharmaceutical Ifosfamide contraindications, Ifosfamide price, Ifosfamide Taj Pharma Ifosfamide SmPC-Taj Pharma Stay connected to all updated on Ifosfamide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Generic Imatinib Mesylate (Veenat Tablets) is used to treat certain types of cancer (such as acute lymphoblastic leukemia, chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). This medicine is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.
Zecyte is used for treatment of leukemias (cancer of white blood cells) and to reduce the severity of symptoms associated with acute myeloid leukemia. Buy Zecyte 250 mg is also used to treat leukemia associated with meningitis (inflammation of protective membrane covering brain and spinal cord).
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
Paracetamol and Ibuprofen - Drug Information - Taj Pharma, Paracetamol and Ibuprofen dose Taj pharmaceuticals Paracetamol and Ibuprofen interactions, Taj Pharmaceutical Paracetamol and Ibuprofen contraindications, Paracetamol and Ibuprofen price, Paracetamol and Ibuprofen Taj Pharma Paracetamol and Ibuprofen 500 mg/150 mg film coated tablets SMPC- Taj Pharma . Stay connected to all updated on Paracetamol and Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Ranitidine is a gastro-intestinal agent that inhibits histamine H2 receptors.
The histamine H2 receptor antagonist ranitidine is used to treat erosive esophagitis, Zollinger-Ellison syndrome, gastric ulcers, GERD, and duodenal ulcers.
Anatomy of the breast for medical/dental students. This presentation also contains MCQs to test your knowledge as well as clinical scenario to apply your knowledge.
Also known as GP note, "Pol" note, PP note
Medical students/ pre-interns/ Family physicians use various notes to guide their general practice at the begining, specially drug doses, common treatments for common diseases etc. These "guides" have been used by many seniors but need to be careful revision before prescribing. Hope to update once I go through them completely.
Also known as GP note, "Pol" note, PP note
Medical students/ pre-interns/ Family physicians use various notes to guide their general practice at the begining, specially drug doses, common treatments for common diseases etc. These "guides" have been used by many seniors but need to be careful revision before prescribing. Hope to update once I go through them completely.
Also known as GP note, "Pol" note, PP note
Medical students/ pre-interns/ Family physicians use various notes to guide their general practice at the begining, specially drug doses, common treatments for common diseases etc. These "guides" have been used by many seniors but need to be careful revision before prescribing. Hope to update once I go through them completely.
Medical students/ pre-interns/ Family physicians use various notes to guide their general practice at the begining, specially drug doses, common treatments for common diseases etc. These "guides" have been used by many seniors but need to be careful revision before prescribing. Hope to update once I go through them completely.
The original teachings of Jesus Christ were an outcome of
Buddhism, says Holger Kersten, a German theology teacher.
Hence one of the titles of the chapters in his book, "The
Original Jesus" (sub-titled 'Buddhist sources of Christianity') is 'Jesus the Buddhist'!
Examination of lower limb in neurology-Short case approach for Final MBBSYapa
Examination of lower limb in neurology-medicine short case approach.
This document was prepared based on the teachings of Dr.Kahathuduwa.
Fonts in blue indicate sample way of presenting the case.
By: Ajaan Mahā Boowa Ñānasampanno
Translated by: Ajaan Paññāvaddho
A senior disciple of Ajaan Mun, Ajaan Khao Anālayo was one of the foremost meditation masters of our time. He always preferred to practice in remote, secluded locations and with such single-minded resolve that his diligence in that respect was unrivaled among his peers in the circle of Thai forest monks. In his frequent encounters with wild animals, Ajaan Khao exhibited a special affinity for elephants.
“The Gift of Dhamma Excels All Other Gifts”
—The Lord Buddha
Dhamma should not be sold like goods in the market place.
Permission to reproduce this publication in any way for free distribution,as a gift of Dhamma, is hereby granted and
no further permission need be obtained.
Reproduction in any way for commercial gain is strictly prohibited.
By: Ajaan Mahā Boowa Ñānasampanno
Translated by: Thānissaro Bhikkhu
This collection of talks was originally given for the benefit of a lay disciple who had come to Ajaan Maha Boowa’s monastery to receive his guidance as she faced her approaching death from bone marrow cancer. These talks offer important lessons about how to learn from pain, illness and death, by seeing through to their ultimate nature and detaching the mind from the suffering associated with them.
“The Gift of Dhamma Excels All Other Gifts”
—The Lord Buddha
Dhamma should not be sold like goods in the market place.
Permission to reproduce this publication in any way for free distribution,as a gift of Dhamma, is hereby granted and
no further permission need be obtained.
Reproduction in any way for commercial gain is strictly prohibited.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. Advices given for the patients on warfarin
1 tab=5mg white in color
Adverse effects
1. Bleeding
2. Epistaxis
3. Haematuria
4. Malena
5. Gum bleeding
6. Excess bleeding from cut injuries
7. Severe headaches/numbness/ faintishness
8. Menorrhagia
9. Purpura
Using warfarin during pregnancy→ fetal defects
Adequacy of warfarin dose is measured by PT/INR. Target value is different for different diseases.
Recommended dose should be used.
Tablets can be used before/ after meals
Should use tablets on same time in everyday. Better to take at 6 pm daily.
If the drug was forgotten, take it on the same day. If could not, you should not double the dose next day.
Should not discontinue without medical advice.
Should inform every doctor who treats you ( dentist/pharmacist) even in a mild illness about warfarin
therapy, specially before surgery.
Inform your doctor whether you are pregnant or willing for a pregnancy.
Avoid sports that can cause severe injuries to prevent severe bleeding.
But athletics, badminton can be continued.
Avoid cut/head injuries as much as posible.
Instances where activity of warfarin can be changed
Foods containing high vit-K levels (beef, green color leaves, vegetables-spinach/ cabbage
Vit K supplements. Therefore try to maintain the vit K levels of diet in a stable level as much as
possible
High alcohol consumption
Should not change/ take any drug without informing a doctor.
Never use aspirin/ aspirin containing drugs without prescription by a doctor.
Any disease/ disease with weight changes can change the warfarin activity
Always keep a card in your pocket indicating that you are on warfarin in case of emergency
Early medical treatment with signs of bleeding.
Attend clinic regularly.
Get PT/ INR checked as advised in the clinic.
High falls/ head injuries, make referals for intracranial bleeding.
Prepared based on the ward teachings- Yapa Wijeratne M/07/189