The Popliteal Fossa is a diamond-shaped space behind the knee joint. It is formed between the muscles in the posterior compartments of the thigh and leg. This anatomical landmark is the major route by which structures pass between the thigh and leg.
The femoral triangle is a wedge-shaped area located within the superomedial aspect of the anterior thigh. The femoral triangle is a hollow region located in the supero-medial part of the anterior thigh.
The Popliteal Fossa is a diamond-shaped space behind the knee joint. It is formed between the muscles in the posterior compartments of the thigh and leg. This anatomical landmark is the major route by which structures pass between the thigh and leg.
The femoral triangle is a wedge-shaped area located within the superomedial aspect of the anterior thigh. The femoral triangle is a hollow region located in the supero-medial part of the anterior thigh.
In human anatomy, the thigh is the area between the hip (pelvis) and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur.
The main artery of the lower limb is the femoral artery. It is a continuation of the external iliac artery (terminal branch of the abdominal aorta). The external iliac becomes the femoral artery when it crosses under the inguinal ligament and enters the femoral triangle.
In the femoral triangle, the profunda femoris artery arises from the posterolateral aspect of the femoral artery. It travels posteriorly and distally, giving off three main branches:
Perforating branches – Consists of three or four arteries that perforate the adductor magnus, contributing to the supply of the muscles in the medial and posterior thigh.
Lateral femoral circumflex artery – Wraps round the anterior, lateral side of the femur, supplying some of the muscles on the lateral aspect of the thigh.
Medial femoral circumflex artery – Wraps round the posterior side of the femur, supplying its neck and head. In a fracture of the femoral neck this artery can easily be damaged, and avascular necrosis of the femur head can occur.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
2. The adductor canal
• The adductor canal (Hu ter’s ca al, subsartorial
canal) is a narrow conical tunnel located in the
thigh.
• It is 15cm long, extending from the apex of
the femoral triangle to the adductor hiatus of the
adductor magnus.
• The canal serves as a passageway from structures
moving between the anterior thigh and posterior
leg.
– It gives passage to the femoral vessels from femoral
triangle to the popliteal fossa.
3.
4.
5. BORDERS
• The adductor canal is triangular in cross section. Its
boundaries are as follows:
• Anterolateral wall:
– It’s created by vastus medialis.
• Posterior (floor):
– It’s created by adductor longus above and adductor
magnus below.
• Medial (roof):
– It if created by a powerful fibrous membrane stretching
across the anterolateral and posterior borders.
– The roofing is overlapped by the sartorius muscle.
• The apex of the adductor canal is marked by
the adductor hiatus – a gap between the adductor and
hamstring attachments of the adductor magnus.
6.
7.
8.
9. The subsartorial plexus of nerves
• The subsartorial plexus of nerves is located on
the roofing underneath the sartorius.
• The plexus is composed by
–Branches from the medial cutaneous nerve of
the thigh.
–The saphenous nerve.
–The anterior section of the obturator nerve.
• It supplies the overlying fascia lata and the
skin
10. Contents
• The adductor canal serves as a passageway from
structures moving between the anterior thigh and
posterior leg.
• It contains:
– Femoral artery,
– Femoral vein,
– Nerve to the vastus medialis
– Saphenous nerve (the largest cutaneous branch of the
femoral nerve).
• Anterior and posterior sections of the obturator nerve (occasional).
• Descending genicular artery, a branch of the femoral artery.
• As the femoral artery and vein exit the canal, they
become the popliteal artery and vein respectively.
11.
12. FEMORAL ARTERY
• The femoral artery enters the canal at the
apex of the femoral triangle, traverses the
entire length of the adductor canal, and leaves
it by going through the tendinous opening in
the adductor magnus (adductor hiatus).
• Inside the canal it produces muscular
branches and a descending genicular branch.
– The descending genicular artery appears before
the femoral artery leaves the canal.
13. FEMORAL VEIN
• The femoral vein is located
posterior to the femoral artery in
the upper part and lateral to the
artery in the lower part.
14. SAPHENOUS NERVE
• The saphenous nerve (longest cutaneous
nerve of the body) crosses the femoral artery
anteriorly from lateral to medial side. It
leaves the canal by piercing the fibrous roof.
• Just before leaving the canal it produces
infrapatellar branch which pierces the
sartorius, and joins the patellar plexus and
supplies the prepatellar skin
15. NERVE TO VASTUS MEDIALIS
• The nerve to vastus medialis (thickest
muscular branch of the femoral
nerve) is located lateral to the
femoral artery, and enters the vastus
medialis in the upper part of the
canal.
16. POSTERIOR SECTION OF OBTURATOR NERVE
• The posterior section of obturator nerve runs
on the anterior outermost layer of the
adductor magnus and ends by supplying
the knee joint.
• The spiral course of the femoral vein and
saphenous nerve with regard to the femoral
artery in the adductor canal is because of
medial rotation of the lower limb during its
development
17. CLINICAL SIGNIFICANCE
• The femoral artery is exposed and ligated in the
adductor canal during surgery for aneurysm of
the popliteal artery.
– The artery is tied in the popliteal fossa immediately
above the popliteal aneurysm.
– This process was initially performed by a well-known
surgeon, Dr John Hunter. The adductor canal was
referred to as after his a e as Hu ter’s ca al.
• After ligation of the femoral artery in the adductor
canal, the collateral circulation is created via arterial
anastomosis around the knee joint.
18. Clinical Relevance – Adductor Canal Block
• In the adductor canal block, local anaesthetic is
administered in the adductor canal to block
the saphenous nerve in isolation, or together with
the nerve to the vastus medialis.
• The block can be used to provide sensory
anaesthesia for procedures involving the distal thigh
and femur, knee and lower leg on the medial side.
• The sartorius and femoral artery are used as
anatomical landmarks to locate the saphenous
nerve.