6. Due to bacterial, viral and parasitic factors
Human intestinal flora protects the bowel
from colonization of pathogens
Intestinal flora can be disturbed by harmful
bacteria and viruses that cause tissue
damage and inflammation
7. Pathogens cause damage and inflammation
by releasing endotoxins that stimulate the
mucosal lining of intestine
Resulting in greater secretion of water and
electrolytes into the intestinal lumen
8. The active secretion of chloride and
bicarbonate ions in the small bowel lead to
inhibition of sodium reabsorption
To balance the excess sodium, large
amounts of proteins- rich fluids are
secreted in the bowel
9. overwhelming the large bowel’s ability to
reabsorb the fluids and leading to diarrhea
Acute Gastroenteritis
