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INTRODUCTION
• Definition:
The series of processes of transforming the neural
plate into the neural tube is called neurulation.
This process begins by the 3rd-4th week of
fertilization.
At this stage, the embryo is known as neurula.
This process is a characteristic feature of vertebrates.
This process leads to the formation of brain and
spinal cord of the central nervous system.
Stages of neurulation
(1) Formation of the neural plate
(2) Formation of neural groove and fold
(3) Formation of neural tube
(4) Closure of the neural-pores
Applied
Neural tube defects are the common congenital
anomalies amoung birth defects.
• Meroencephaly or anencephaly
Partial absence of brain and occur due to failure
of closure of neural tube in cranial region
• Spina bifida and Rachischisis
These defects occur due to failure of closure in
caudal region of tube.

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Neurulation and the formation of the neural tube

  • 1.
  • 2. INTRODUCTION • Definition: The series of processes of transforming the neural plate into the neural tube is called neurulation. This process begins by the 3rd-4th week of fertilization. At this stage, the embryo is known as neurula. This process is a characteristic feature of vertebrates. This process leads to the formation of brain and spinal cord of the central nervous system.
  • 3.
  • 4.
  • 5. Stages of neurulation (1) Formation of the neural plate (2) Formation of neural groove and fold (3) Formation of neural tube (4) Closure of the neural-pores
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. Applied Neural tube defects are the common congenital anomalies amoung birth defects. • Meroencephaly or anencephaly Partial absence of brain and occur due to failure of closure of neural tube in cranial region • Spina bifida and Rachischisis These defects occur due to failure of closure in caudal region of tube.