This document summarizes statistics on cancer increases from 1973-1999 and potential causes and preventative measures. It finds that certain cancers have increased over 100% in this period. Factors that may contribute to cancer risk include refined carbohydrates, sugar, insulin levels, inflammatory eicosanoids, and lack of anti-inflammatory nutrients. Many natural compounds show promise in preventing or treating cancer, including curcumin, resveratrol, vitamin D, selenium, iodine, indole-3-carbinol, coenzyme Q10, lycopene, green tea, and artemisinin. Maintaining optimal levels of these and other antioxidants may help reduce cancer risks and progression.
We all know about the seriousness of cancer. Diet plays an important role in causing, preventing and treating cancer. Let’s take a look at some of the most common cancer-causing and anti-cancer foods.
Modulating Oncometabolic Syndrome: Integrative Diet & Nutrition to Complement...Jeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at CMBM's Food as Medicine conference, Indianapolis 2013. Oncometabolic Syndrome is a cluster of metabolic factors that influence the growth and progression of cancer. Standard lab testing can be used to assess nutritional factors that may influence cancer outcomes, tailor a protocol to an individual's unique needs, and evaluate the efficacy of the nutrition intervention in modulating these factors.
This document discusses strategic planning for cancer prevention. It provides information on various dietary and environmental factors that can increase cancer risk such as high glycemic diets, oxidative overload, inflammation, and exposure to toxins like PBDEs and BPA. It summarizes several studies that show relationships between certain foods/supplements and reduced cancer rates, such as broccoli consumption being associated with lower prostate cancer risk and green tea supplementation correlating with fewer prostate cancer cases. The document advocates for lifestyle changes like plant-based diets, exercise, and detoxification to potentially prevent or slow cancer progression.
Radiation Therapy: Nutritional Strategies to Improve OutcomesJeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at "Integrative Cancer Medicine: Clinical Applications of Cancer Strategies" conference April 26-29, 2013, Scottsdale AZ. Explore the mechanisms of tumor resistance to radiation therapy. Review diet, lifestyle, nutritional and botanical strategies for bolstering therapeutic efficacy. Employ selective radioprotectors to lessen injury to healthy tissues. Take into consideration the unfavorable consequences of radiotherapy, which can potentially increase the oncogenic potential of surviving tumor cells, and develop a plan for blocking these pathways. Cases will be presented from 15 yrs experience of the Nutritional Solutions team in counseling clients undergoing radiation therapy for Glioblastoma multiforme brain tumors, colorectal, head-and-neck, breast and gynecologic cancers.
Harnessing the Power of Nutrition to Complement Brain Tumor CareJeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at the 1st Annual Brains Matter conference (Sept 2012 in Seattle), sponsored by the Chris Elliott Foundation. Learn how nutrition can play a powerful role to influence the terrain (environment) surrounding cancer cells. Discover foods that can "talk" to your genes, suppressing oncogenes and turning on tumor suppressor genes. Explore simple diet and lifestyle changes you can make to nourish your wellness when facing a brain tumor diagnosis.
Cancer Survivorship Challenges and OpportunitiesGaynorOncology
This document discusses cancer survivorship challenges and opportunities. It provides statistics on cancer survivors such as over 60% being over age 65 and the most common cancer sites being breast, prostate, and colorectal. It then discusses trends in improved 5-year survival rates for many cancer sites from 1975-2003. The document outlines goals for cancer survivors including monitoring biomarkers, maintaining wellness through lifestyle factors like nutrition and exercise, and becoming active participants in their care. Biomarkers discussed include fasting insulin levels, IGF-1, and drug metabolism biomarkers. The roles of lifestyle factors like meditation, yoga, exercise, music, spirituality, and nutrition including soy and vitamin D are also summarized.
We all know about the seriousness of cancer. Diet plays an important role in causing, preventing and treating cancer. Let’s take a look at some of the most common cancer-causing and anti-cancer foods.
Modulating Oncometabolic Syndrome: Integrative Diet & Nutrition to Complement...Jeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at CMBM's Food as Medicine conference, Indianapolis 2013. Oncometabolic Syndrome is a cluster of metabolic factors that influence the growth and progression of cancer. Standard lab testing can be used to assess nutritional factors that may influence cancer outcomes, tailor a protocol to an individual's unique needs, and evaluate the efficacy of the nutrition intervention in modulating these factors.
This document discusses strategic planning for cancer prevention. It provides information on various dietary and environmental factors that can increase cancer risk such as high glycemic diets, oxidative overload, inflammation, and exposure to toxins like PBDEs and BPA. It summarizes several studies that show relationships between certain foods/supplements and reduced cancer rates, such as broccoli consumption being associated with lower prostate cancer risk and green tea supplementation correlating with fewer prostate cancer cases. The document advocates for lifestyle changes like plant-based diets, exercise, and detoxification to potentially prevent or slow cancer progression.
Radiation Therapy: Nutritional Strategies to Improve OutcomesJeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at "Integrative Cancer Medicine: Clinical Applications of Cancer Strategies" conference April 26-29, 2013, Scottsdale AZ. Explore the mechanisms of tumor resistance to radiation therapy. Review diet, lifestyle, nutritional and botanical strategies for bolstering therapeutic efficacy. Employ selective radioprotectors to lessen injury to healthy tissues. Take into consideration the unfavorable consequences of radiotherapy, which can potentially increase the oncogenic potential of surviving tumor cells, and develop a plan for blocking these pathways. Cases will be presented from 15 yrs experience of the Nutritional Solutions team in counseling clients undergoing radiation therapy for Glioblastoma multiforme brain tumors, colorectal, head-and-neck, breast and gynecologic cancers.
Harnessing the Power of Nutrition to Complement Brain Tumor CareJeanne M Wallace PhD
Presentation by Jeanne M. Wallace, PhD, CNC, at the 1st Annual Brains Matter conference (Sept 2012 in Seattle), sponsored by the Chris Elliott Foundation. Learn how nutrition can play a powerful role to influence the terrain (environment) surrounding cancer cells. Discover foods that can "talk" to your genes, suppressing oncogenes and turning on tumor suppressor genes. Explore simple diet and lifestyle changes you can make to nourish your wellness when facing a brain tumor diagnosis.
Cancer Survivorship Challenges and OpportunitiesGaynorOncology
This document discusses cancer survivorship challenges and opportunities. It provides statistics on cancer survivors such as over 60% being over age 65 and the most common cancer sites being breast, prostate, and colorectal. It then discusses trends in improved 5-year survival rates for many cancer sites from 1975-2003. The document outlines goals for cancer survivors including monitoring biomarkers, maintaining wellness through lifestyle factors like nutrition and exercise, and becoming active participants in their care. Biomarkers discussed include fasting insulin levels, IGF-1, and drug metabolism biomarkers. The roles of lifestyle factors like meditation, yoga, exercise, music, spirituality, and nutrition including soy and vitamin D are also summarized.
The document summarizes research on factors influencing cancer risk across the lifespan, from fetal development through adulthood. It discusses how characteristics like birth weight, adult height and weight, and physical activity levels impact cancer risk. Early life nutrition is particularly important, as it can program metabolic and hormonal regulation in ways that affect cancer vulnerability later in life. Maintaining the right balance of nutrients, including amino acids like glycine, appears key to supporting health and minimizing cancer risk.
This document discusses cancer globally and in India. It provides statistics on cancer incidence and mortality worldwide and in different countries/regions. Some key points:
- Total estimated new cancer cases worldwide in 2012 was 14 million, with 8.2 million cancer deaths.
- Developing countries account for about 6.7 million new cases and 4.7 million deaths annually.
- The three most common cancers globally are lung, breast, and colorectal cancer.
- In India, estimated new cancer cases in 2010 were 950,000, with breast cancer being the most common among women and lung cancer among men.
- Risk factors for cancer include tobacco use, diet, infection, and lack of screening/early detection
Overweight and obesity are associated with worse cancer outcomes and prognosis. Adipose tissue surrounding tumors, called cancer-associated adipocytes, secrete inflammatory molecules like IL-6 that can promote tumor growth, invasion, and metastasis. In obese conditions, adipose tissue develops a pro-inflammatory state characterized by immune cell infiltration and cytokine expression. This inflamed environment may further enhance cancer-associated adipocytes' effects on tumor progression. Targeting inflammation in adipose tissue, such as with IL-6 blocking antibodies, could potentially improve cancer treatment outcomes, especially in obese patients where adipose tissue inflammation is increased.
This document discusses the relationship between diet and cancer development. It finds that 30-40% of cancers could be prevented through lifestyle and dietary changes. Specifically, it identifies several dietary factors that may increase cancer risk, such as a low fiber diet, red meat consumption, and an imbalance of omega-3 and omega-6 fats. Conversely, a diet high in fruits and vegetables may lower cancer risk due to antioxidants and other protective compounds. Certain foods like salmon, tomatoes, and soy are highlighted as containing nutrients that inhibit cancerogenesis. The role of probiotics and maintaining a healthy glucose metabolism are also discussed in cancer prevention.
Tim Byers Presentations International Congress on ObesityWCRF International
This document summarizes the epidemiologic and biologic mechanisms linking obesity to increased cancer risk. Obesity is associated with increased risks of cancers of the breast, endometrium, colon, kidney, pancreas, and esophagus. Potential mechanisms include increased production of estrogens, insulin, inflammatory cytokines, and other growth factors induced by excess body fat. While weight loss is associated with reduced cancer risk and changes in metabolic factors in observational studies, large randomized trials are still needed to confirm causal relationships. Understanding the biologic pathways involved could help identify prevention and treatment targets.
This document summarizes a presentation on weight loss and cancer risk reduction. It discusses how weight gain increases cancer risk, and how modest weight loss through dietary interventions can reduce cancer risk. Clinical trials show intermittent energy restriction may be more effective for weight loss and insulin reduction than daily energy restriction. Weight loss interventions are also discussed after a cancer diagnosis, though randomized trials are still needed. The presentation concludes by discussing targeting overweight individuals for weight loss interventions to reduce cancer risk.
The document discusses the relationship between obesity and breast cancer. It notes that obesity is a risk factor for breast cancer in postmenopausal women and is associated with poorer prognosis through various mechanisms like increased estrogen production. Managing obesity through weight loss and medications can help improve outcomes for breast cancer by reducing levels of hormones and inflammatory markers linked to tumor growth. Future research is exploring new drugs targeting obesity-related pathways.
24 janvier CROQUER LA VIE - Dr Thomas Seyfriedcroquer_la_vie
1) Cancer may be best defined as a metabolic disease of the mitochondria rather than solely a genetic disease.
2) Therapies like calorie restriction and ketogenic diets that target energy metabolism can effectively manage tumor growth in mouse models and some human cases by lowering blood glucose and raising ketone levels.
3) A restricted ketogenic diet combined with other metabolic therapies may provide a novel non-toxic strategy for managing malignant cancers.
This study investigated the association between folate intake and BMI/body fat in adult women. The researchers divided 69 women into high and low folate to calorie intake ratio groups using a cutoff of 1 microgram of folate per 4 calories. They found that women with a higher folate to calorie ratio had significantly lower average BMIs and percentages of body fat compared to those with a lower ratio. Additionally, older women tended to be in the lower folate intake group. The results provide support that higher folate intake through food sources correlates with lower BMI and body fatness in adult women.
This document discusses the link between diabetes and cancer. It notes that cancer and diabetes are diagnosed together more frequently than expected by chance. Several risk factors are shared between the two diseases, including age, diet, obesity, and lifestyle factors. The document explores how insulin and IGF-1 may influence cancer development via their effects on cell growth pathways. It reviews evidence on the effects of different diabetes medications, including some studies that found certain insulin analogs may increase cancer risk. Several cohort studies on the cancer risks of insulin glargine are also summarized.
The document summarizes findings from the European Prospective Investigation into Cancer and Nutrition (EPIC) study on relationships between diet and cancer risk. It reports that red and processed meat strongly increased gastric and colorectal cancer risk while adherence to a Mediterranean diet decreased gastric cancer risk. Fiber intake reduced gastric and colorectal cancers while calcium intake lowered colorectal cancer risk.
Nutrition: Biochemical correlates of anemia in Cambodian women of reproducti...IFSD14
1) The study examined biochemical correlates of anemia in Cambodian women of reproductive age, finding over 40% had a genetic hemoglobin disorder like heterozygous E trait or homozygous E.
2) Nearly 30% of women had anemia, most cases being microcytic, but few had biochemical evidence of iron, vitamin B12, folate, or vitamin A deficiencies. Iron deficiency was less than 1% based on ferritin and transferrin receptor.
3) Having a genetic hemoglobin disorder was associated with higher rates of anemia and tissue iron deficiency compared to those without a disorder, though iron deficiency anemia was still less than 1%.
This document summarizes research on the relationships between obesity, physical activity, and breast cancer risk and prognosis. It finds that obesity is positively associated with breast cancer risk and mortality in postmenopausal women. Physical activity is associated with reduced breast cancer risk and improved survival. Obesity may influence breast cancer through increased estrogen levels, insulin resistance, and inflammation. Weight loss interventions show improvements in relevant biomarkers and health outcomes for breast cancer survivors. The ENERGY trial aims to test if weight loss counseling improves weight and physical functioning in breast cancer survivors.
Metastatic Breast Cancer and The Tumor MicroenvironmentAmandaRussell40
This document summarizes research on how the tumor microenvironment influences metastasis at every step of the metastatic cascade. Key points include: (1) the microenvironment can suppress or promote tumorigenesis; (2) the perivascular niche protects disseminated tumor cells and keeps them dormant; (3) targeting the integrin receptors that mediate tumor cell interactions with the vascular niche can sensitize dormant tumor cells to chemotherapy and prevent metastasis without increasing toxicity.
Considering the mechanisms behind cancer cachexia-anorexia can inform wiser n...Jeanne M Wallace PhD
Unwanted weight loss and lack of interest in food drives many cancer patients to conventional canned nutrition formulas like Ensure, but these may actually foster the oncogenic process. This article outlines the underlying physiology of cachexia and compares various feeding formulas including holistic nutrition options.
Ueda2016 diabetes & cancer - mesbah kamelueda2015
Diabetes and certain cancers are linked by shared risk factors like obesity and age. People with diabetes have higher risks of cancers of the liver, pancreas, endometrium, and colon and breast cancers. The biological mechanisms linking the diseases involve insulin and insulin-like growth factors stimulating cancer cell growth. While hyperglycemia is not an independent risk factor, it can worsen cancer outcomes. Metformin may reduce cancer risk compared to other diabetes medications by activating AMPK, an energy sensor that puts cells in energy-saving mode and inhibits cancer cell growth. Further research is still needed to fully understand the diabetes-cancer relationship and its implications for treatment and management.
This document summarizes research on the developmental origins of obesity and cancer risk. It finds that both low and high birth weights are associated with increased risk of diseases like diabetes and cardiovascular disease later in life. Rapid postnatal growth and catch-up growth are also linked to obesity and disease risk. Experimental studies with animal models demonstrate that maternal diet, nutrition during pregnancy and lactation, and post-weaning diets can program offspring's risk of obesity and cancer through metabolic and epigenetic mechanisms.
Type 2 diabetes is associated with increased risk of certain cancers like liver, pancreas, endometrium, colorectal, breast and bladder cancers. The relationship is complex with factors like reverse causality, detection bias, shared risk factors between diabetes and cancer, and the effects of antidiabetic medications influencing cancer risk. Metformin appears to have a neutral or protective effect on cancer risk while insulin and sulfonylureas may increase risk, though data is still limited. Further research is needed to fully understand the relationship between diabetes, antidiabetic treatments and cancer.
The document discusses omega-3 fatty acids and their potential benefits for cancer therapy and prevention. Preclinical studies show omega-3s may suppress cancer growth and increase the efficacy of chemotherapy or radiation. Potential mechanisms for this include reducing inflammation and oxidative stress, inhibiting cell proliferation and angiogenesis, and inducing cancer cell death. Limited clinical studies also provide some evidence that omega-3 supplements may benefit cancer patients by reducing cachexia and improving responses to treatment for cancers like breast cancer.
Nutrition in Cancer Prevention and TreatmentTim Crowe
This presentation will help you to understand the influence that dietary and lifestyle factors play in the prevention and causation of cancer. It outlines the important nutritional considerations for patients undergoing treatment for cancer and reviews procedures to improve patient safety by knowing the risks and benefits of antioxidant supplementation during cancer treatment
Cancer is a leading cause of death in the US and around the world. The document discusses various causes of cancer like tobacco, alcohol, red meat, processed meat, and lack of exercise. It also discusses ways to prevent cancer through diet and lifestyle changes like eating more plants and less red meat and processed meat. For cancer treatment, the document discusses surgery, radiation, chemotherapy and their side effects, as well as the limitations of modern medicine and importance of lifestyle in recovery from cancer.
The document summarizes research on factors influencing cancer risk across the lifespan, from fetal development through adulthood. It discusses how characteristics like birth weight, adult height and weight, and physical activity levels impact cancer risk. Early life nutrition is particularly important, as it can program metabolic and hormonal regulation in ways that affect cancer vulnerability later in life. Maintaining the right balance of nutrients, including amino acids like glycine, appears key to supporting health and minimizing cancer risk.
This document discusses cancer globally and in India. It provides statistics on cancer incidence and mortality worldwide and in different countries/regions. Some key points:
- Total estimated new cancer cases worldwide in 2012 was 14 million, with 8.2 million cancer deaths.
- Developing countries account for about 6.7 million new cases and 4.7 million deaths annually.
- The three most common cancers globally are lung, breast, and colorectal cancer.
- In India, estimated new cancer cases in 2010 were 950,000, with breast cancer being the most common among women and lung cancer among men.
- Risk factors for cancer include tobacco use, diet, infection, and lack of screening/early detection
Overweight and obesity are associated with worse cancer outcomes and prognosis. Adipose tissue surrounding tumors, called cancer-associated adipocytes, secrete inflammatory molecules like IL-6 that can promote tumor growth, invasion, and metastasis. In obese conditions, adipose tissue develops a pro-inflammatory state characterized by immune cell infiltration and cytokine expression. This inflamed environment may further enhance cancer-associated adipocytes' effects on tumor progression. Targeting inflammation in adipose tissue, such as with IL-6 blocking antibodies, could potentially improve cancer treatment outcomes, especially in obese patients where adipose tissue inflammation is increased.
This document discusses the relationship between diet and cancer development. It finds that 30-40% of cancers could be prevented through lifestyle and dietary changes. Specifically, it identifies several dietary factors that may increase cancer risk, such as a low fiber diet, red meat consumption, and an imbalance of omega-3 and omega-6 fats. Conversely, a diet high in fruits and vegetables may lower cancer risk due to antioxidants and other protective compounds. Certain foods like salmon, tomatoes, and soy are highlighted as containing nutrients that inhibit cancerogenesis. The role of probiotics and maintaining a healthy glucose metabolism are also discussed in cancer prevention.
Tim Byers Presentations International Congress on ObesityWCRF International
This document summarizes the epidemiologic and biologic mechanisms linking obesity to increased cancer risk. Obesity is associated with increased risks of cancers of the breast, endometrium, colon, kidney, pancreas, and esophagus. Potential mechanisms include increased production of estrogens, insulin, inflammatory cytokines, and other growth factors induced by excess body fat. While weight loss is associated with reduced cancer risk and changes in metabolic factors in observational studies, large randomized trials are still needed to confirm causal relationships. Understanding the biologic pathways involved could help identify prevention and treatment targets.
This document summarizes a presentation on weight loss and cancer risk reduction. It discusses how weight gain increases cancer risk, and how modest weight loss through dietary interventions can reduce cancer risk. Clinical trials show intermittent energy restriction may be more effective for weight loss and insulin reduction than daily energy restriction. Weight loss interventions are also discussed after a cancer diagnosis, though randomized trials are still needed. The presentation concludes by discussing targeting overweight individuals for weight loss interventions to reduce cancer risk.
The document discusses the relationship between obesity and breast cancer. It notes that obesity is a risk factor for breast cancer in postmenopausal women and is associated with poorer prognosis through various mechanisms like increased estrogen production. Managing obesity through weight loss and medications can help improve outcomes for breast cancer by reducing levels of hormones and inflammatory markers linked to tumor growth. Future research is exploring new drugs targeting obesity-related pathways.
24 janvier CROQUER LA VIE - Dr Thomas Seyfriedcroquer_la_vie
1) Cancer may be best defined as a metabolic disease of the mitochondria rather than solely a genetic disease.
2) Therapies like calorie restriction and ketogenic diets that target energy metabolism can effectively manage tumor growth in mouse models and some human cases by lowering blood glucose and raising ketone levels.
3) A restricted ketogenic diet combined with other metabolic therapies may provide a novel non-toxic strategy for managing malignant cancers.
This study investigated the association between folate intake and BMI/body fat in adult women. The researchers divided 69 women into high and low folate to calorie intake ratio groups using a cutoff of 1 microgram of folate per 4 calories. They found that women with a higher folate to calorie ratio had significantly lower average BMIs and percentages of body fat compared to those with a lower ratio. Additionally, older women tended to be in the lower folate intake group. The results provide support that higher folate intake through food sources correlates with lower BMI and body fatness in adult women.
This document discusses the link between diabetes and cancer. It notes that cancer and diabetes are diagnosed together more frequently than expected by chance. Several risk factors are shared between the two diseases, including age, diet, obesity, and lifestyle factors. The document explores how insulin and IGF-1 may influence cancer development via their effects on cell growth pathways. It reviews evidence on the effects of different diabetes medications, including some studies that found certain insulin analogs may increase cancer risk. Several cohort studies on the cancer risks of insulin glargine are also summarized.
The document summarizes findings from the European Prospective Investigation into Cancer and Nutrition (EPIC) study on relationships between diet and cancer risk. It reports that red and processed meat strongly increased gastric and colorectal cancer risk while adherence to a Mediterranean diet decreased gastric cancer risk. Fiber intake reduced gastric and colorectal cancers while calcium intake lowered colorectal cancer risk.
Nutrition: Biochemical correlates of anemia in Cambodian women of reproducti...IFSD14
1) The study examined biochemical correlates of anemia in Cambodian women of reproductive age, finding over 40% had a genetic hemoglobin disorder like heterozygous E trait or homozygous E.
2) Nearly 30% of women had anemia, most cases being microcytic, but few had biochemical evidence of iron, vitamin B12, folate, or vitamin A deficiencies. Iron deficiency was less than 1% based on ferritin and transferrin receptor.
3) Having a genetic hemoglobin disorder was associated with higher rates of anemia and tissue iron deficiency compared to those without a disorder, though iron deficiency anemia was still less than 1%.
This document summarizes research on the relationships between obesity, physical activity, and breast cancer risk and prognosis. It finds that obesity is positively associated with breast cancer risk and mortality in postmenopausal women. Physical activity is associated with reduced breast cancer risk and improved survival. Obesity may influence breast cancer through increased estrogen levels, insulin resistance, and inflammation. Weight loss interventions show improvements in relevant biomarkers and health outcomes for breast cancer survivors. The ENERGY trial aims to test if weight loss counseling improves weight and physical functioning in breast cancer survivors.
Metastatic Breast Cancer and The Tumor MicroenvironmentAmandaRussell40
This document summarizes research on how the tumor microenvironment influences metastasis at every step of the metastatic cascade. Key points include: (1) the microenvironment can suppress or promote tumorigenesis; (2) the perivascular niche protects disseminated tumor cells and keeps them dormant; (3) targeting the integrin receptors that mediate tumor cell interactions with the vascular niche can sensitize dormant tumor cells to chemotherapy and prevent metastasis without increasing toxicity.
Considering the mechanisms behind cancer cachexia-anorexia can inform wiser n...Jeanne M Wallace PhD
Unwanted weight loss and lack of interest in food drives many cancer patients to conventional canned nutrition formulas like Ensure, but these may actually foster the oncogenic process. This article outlines the underlying physiology of cachexia and compares various feeding formulas including holistic nutrition options.
Ueda2016 diabetes & cancer - mesbah kamelueda2015
Diabetes and certain cancers are linked by shared risk factors like obesity and age. People with diabetes have higher risks of cancers of the liver, pancreas, endometrium, and colon and breast cancers. The biological mechanisms linking the diseases involve insulin and insulin-like growth factors stimulating cancer cell growth. While hyperglycemia is not an independent risk factor, it can worsen cancer outcomes. Metformin may reduce cancer risk compared to other diabetes medications by activating AMPK, an energy sensor that puts cells in energy-saving mode and inhibits cancer cell growth. Further research is still needed to fully understand the diabetes-cancer relationship and its implications for treatment and management.
This document summarizes research on the developmental origins of obesity and cancer risk. It finds that both low and high birth weights are associated with increased risk of diseases like diabetes and cardiovascular disease later in life. Rapid postnatal growth and catch-up growth are also linked to obesity and disease risk. Experimental studies with animal models demonstrate that maternal diet, nutrition during pregnancy and lactation, and post-weaning diets can program offspring's risk of obesity and cancer through metabolic and epigenetic mechanisms.
Type 2 diabetes is associated with increased risk of certain cancers like liver, pancreas, endometrium, colorectal, breast and bladder cancers. The relationship is complex with factors like reverse causality, detection bias, shared risk factors between diabetes and cancer, and the effects of antidiabetic medications influencing cancer risk. Metformin appears to have a neutral or protective effect on cancer risk while insulin and sulfonylureas may increase risk, though data is still limited. Further research is needed to fully understand the relationship between diabetes, antidiabetic treatments and cancer.
The document discusses omega-3 fatty acids and their potential benefits for cancer therapy and prevention. Preclinical studies show omega-3s may suppress cancer growth and increase the efficacy of chemotherapy or radiation. Potential mechanisms for this include reducing inflammation and oxidative stress, inhibiting cell proliferation and angiogenesis, and inducing cancer cell death. Limited clinical studies also provide some evidence that omega-3 supplements may benefit cancer patients by reducing cachexia and improving responses to treatment for cancers like breast cancer.
Nutrition in Cancer Prevention and TreatmentTim Crowe
This presentation will help you to understand the influence that dietary and lifestyle factors play in the prevention and causation of cancer. It outlines the important nutritional considerations for patients undergoing treatment for cancer and reviews procedures to improve patient safety by knowing the risks and benefits of antioxidant supplementation during cancer treatment
Cancer is a leading cause of death in the US and around the world. The document discusses various causes of cancer like tobacco, alcohol, red meat, processed meat, and lack of exercise. It also discusses ways to prevent cancer through diet and lifestyle changes like eating more plants and less red meat and processed meat. For cancer treatment, the document discusses surgery, radiation, chemotherapy and their side effects, as well as the limitations of modern medicine and importance of lifestyle in recovery from cancer.
The document discusses colon cancer prevalence, risk factors, and preventative methods. It notes that colon cancer rates increase after age 50 and are higher in black men. A high fiber diet from foods like grains, vegetables, fruits, and beans may help prevent colon cancer by promoting regular bowel movements and reducing carcinogen exposure in the colon. Regular screening can detect pre-cancerous polyps and detect cancer early to improve outcomes.
The document discusses cancer and its causes. It defines cancer as uncontrolled cell growth that forms tumors. Some key points:
- Cancer is caused by genetic and environmental factors like tobacco use, infections, diet, obesity, and radiation.
- A healthy diet high in plants and fiber and low in red meat and processed foods can help prevent cancer. Avoiding tobacco, excessive alcohol, grilling meats, and exposure to pollutants also reduces risk.
- Early cancer often has no symptoms, so screening like mammograms and colonoscopies can find cancers early. Diagnosis involves scans, biopsies, and molecular tests to identify abnormal cells.
- Making lifestyle changes around diet, exercise,
Food choices can help prevent cancer and, when cancer has been diagnosed, nutrition can improve survival. These links between diet and cancer are nothing short of dramatic. And now you can learn how certain dietary patterns help people diagnosed with cancer live longer, healthier lives.
This document discusses the health benefits of various foods and food components. It notes that organic milk contains higher levels of vitamins E, beta carotene, and lutein/zeaxanthine compared to conventional milk. Various fruits like blueberries, strawberries, raspberries, cranberries, and apples are highlighted for their antioxidant properties. Seafood is described as rich in vitamins D and iodine, as well as omega-3 fatty acids. Fermented dairy is said to contain beneficial bacteria, enzymes, vitamins, and minerals that support immunity and bone health. Overall, the document promotes the health advantages of traditional, whole foods diets compared to modern Western diets.
Cancer Chemo Radiation Concurrent Supplementsfondas vakalis
I do not actually have experiences like washing windows or dealing with pigeons. I'm an AI assistant created by Anthropic to be helpful, harmless, and honest.
Using food as your medicine discusses how nutrition impacts cancer. It notes that cancer rates are increasing globally and lifestyle factors like diet account for 90-95% of cancer cases. A plant-based diet high in fruits and vegetables can reduce cancer risk by 40-64% and mortality by 1/3 by supporting the body's natural defenses and reducing inflammation. Specific foods like red meat and saturated fats may promote cancer while phytonutrients in plants like broccoli act as antioxidants and detoxifiers. Maintaining a balanced, mostly plant-based diet with moderate protein and calories can help prevent and fight cancer development and progression.
This document discusses cancer prevention through lifestyle modifications. It notes that 50-65% of cancer cases are potentially preventable by lifestyle changes like not smoking, maintaining a healthy diet and weight, limiting alcohol intake, and exercising regularly. Specific lifestyle risk factors that can increase cancer risk, such as smoking, poor diet, obesity, excessive alcohol, infections, and radiation exposure, are reviewed. The document emphasizes the role of diet, recommending a Mediterranean-style diet with fruits/vegetables and fish to reduce overall cancer risk.
Phytosterols for Cancer Treatment PowerpointJosh Nooner
Phytosterols show promise for cancer treatment based on several animal, in vitro, and human studies. Animal studies found that phytosterol supplementation delayed breast cancer tumor onset and reduced prostate cancer growth. In vitro studies demonstrated that phytosterols increased cancer cell apoptosis, decreased proliferation, and increased tumor suppressor genes. A human epidemiological study associated higher phytosterol intake with a 50% reduced risk of lung cancer. Collectively, the studies suggest phytosterols may exert anticancer effects through reducing oxidative damage, inhibiting growth and metastasis, and altering gene expression. However, more research is still needed, including long-term human clinical trials.
Phytosterols for cancer treatment powerpointJosh Nooner
Phytosterols show promise for cancer treatment based on several animal, in vitro, and human studies. Animal studies found that phytosterol supplementation delayed breast cancer tumor onset and reduced prostate cancer growth. In vitro studies demonstrated that phytosterols increased cancer cell apoptosis, decreased proliferation, and increased tumor suppressor genes. A human epidemiological study associated higher phytosterol intake with a 50% reduced risk of lung cancer. Overall, the research suggests phytosterols may exert anticancer effects through reducing oxidative damage and preventing tumor growth and progression.
This document discusses the health benefits of a plant-based diet and the risks associated with animal product consumption. It provides several studies that show vegetarians and vegans have lower rates of chronic diseases like cancer, heart disease, diabetes and obesity. Cancer risks are higher with diets high in fat, meat and dairy. Plant foods like fruits, vegetables, whole grains and legumes contain antioxidants and other beneficial compounds that protect against disease initiation and promotion.
Diet effects on cancers among the personal behaviorssamuelmerga3
This document discusses the relationship between diet and cancer risk. It summarizes evidence from epidemiological studies on how certain foods like red meat, dairy products, fruits and vegetables, fiber and glycemic load may impact cancer risk. While certain foods like processed meats and sugary foods appear to increase risk, the evidence for most foods is mixed and inconclusive. Large randomized controlled trials of supplements like selenium and vitamin E did not find a protective effect against cancer. Overall, the best diet for cancer prevention is one that emphasizes plant foods and limits red and processed meats.
Breast cancer is one of the most common cancers in women. Several factors can increase a woman's risk of developing breast cancer, including family history, lifestyle factors like obesity and lack of exercise, and hormonal influences. Regular screening through self-exams and mammograms can help detect breast cancer early when it is most treatable. Diet and nutrition also play an important role, as certain foods and dietary patterns may promote inflammation and increase cancer risk, while others provide protective antioxidants.
This document summarizes issues related to women's cancer and modern cancer treatment approaches. It notes that cancer rates have increased dramatically in recent decades despite little change in survival rates. Conventional treatments like chemotherapy, radiation and surgery are discussed, as well as alternatives like diet changes, supplements and non-toxic therapies. Concerns about environmental toxins, pharmaceutical drugs, and other modern factors that may contribute to cancer risks are also presented. The document advocates for patient empowerment and informed consent regarding cancer treatment options.
This document discusses several health issues facing Americans such as high rates of diabetes, obesity, and heart disease. It attributes these problems to an increasing reliance on processed foods high in sugar, unhealthy fats, and carbohydrates since the 1970s. In particular, it notes the rise of fast food consumption and the replacement of traditional diets high in nutrients with modern diets deficient in important fatty acids and micronutrients. The document advocates returning to whole, traditional foods as a way to address inflammation and chronic disease.
This document discusses the poor state of American health and links it to the standard American diet high in processed foods, sugar, and refined carbohydrates. It notes the rise of fast food consumption and obesity rates. Several studies are cited showing the traditional diets of other populations have higher nutrient density and lower rates of diseases like heart disease and cancer compared to the modern Western diet. Grass-fed animal products and traditional diets contain higher levels of beneficial fatty acids like CLA and omega-3s that may protect against cancer, weight gain, and inflammation.
This document discusses the poor state of American health and links it to the standard American diet high in processed foods, sugar, and refined carbohydrates. It notes the rise of fast food consumption and obesity rates. Several studies are cited showing the traditional diets of other populations have higher nutrient density and lower rates of diseases like heart disease and cancer compared to the modern Western diet. Grass-fed animal products and traditional diets contain higher levels of beneficial fatty acids like CLA and omega-3s that may protect against cancer, weight gain, and inflammation.
Similar to The More Than Ten Things You Should Do to Prevent or Treat Cancer (20)
Marthe Cohn was a Jewish French spy who risked her life to gather intelligence for the French resistance during WWII. She infiltrated Nazi Germany using her fluent German and managed to discover key military information. As a result, the French army was able to achieve an important victory. Cohn went on to have a long career as a nurse and nurse anesthetist. She has received numerous honors for her wartime heroism and courageously fights to keep the memory of the Holocaust alive.
This document provides links to resources about organic gardening techniques, urban farming, rainwater harvesting, green roofs, straight vegetable oil vehicles, garden therapy, volunteering on organic farms in Europe, solar energy training, and eco-friendly coffee beans. It discusses how organic gardening technologies can increase plant yields by 400% and provides catalogs and manuals about topics such as city farming, backyard farming, rain gardens, and aquaponics systems. The links provide free information for organic and sustainable living practices.
Ruth Jones, a Christian teacher without a master's degree or administrative experience, was unexpectedly named principal of a struggling inner city elementary school in Grand Rapids, Michigan that was on the verge of closure due to poor academic performance. Through prayer, addressing students' practical needs, and recruiting volunteers, Jones led a dramatic turnaround of the school over 20 years. Test scores and graduation rates increased sharply, and the school now has a waiting list despite originally facing closure. Jones attributes the school's success to aligning herself with God.
- Coconut oil may help slow or prevent Alzheimer's disease in some people by providing an alternative fuel for brain cells in the form of ketones. Dr. Mary Newport put her husband Steve, who had Alzheimer's, on a diet supplemented with coconut oil, which led to improvements in his symptoms and cognitive abilities.
- Researchers have developed a ketone ester that is more potent than coconut oil, but it is very expensive to produce. Coconut oil remains a viable alternative source of ketones. Taking coconut oil may also help with other neurological diseases due to its ability to increase ketone levels and good cholesterol while reducing bad bacteria.
A teacher in Baltimore transformed the lives of students from the slums. In the 1920s, college students evaluated 200 boys from the slums and said they had no chance of success. Twenty-five years later, it was found that 176 of the 180 boys who could be located had achieved success as lawyers, doctors, and businessmen. The professor interviewed each man and they all credited their success to a teacher who had loved and believed in them. When interviewed, the elderly teacher said her simple method was that she loved those boys.
Robert Raikes witnessed the poor conditions of children in Gloucester, England in the late 18th century due to the Industrial Revolution. This inspired him to create the first Sunday school to educate and reform street children. The Sunday school used the Bible as its textbook and proved hugely successful in improving behavior and civic responsibility. Raikes' idea then spread across Britain and to other parts of Europe and America, revolutionizing religious education of children and community outreach efforts of churches. Late in life, Raikes had a profound spiritual experience witnessing a young girl reading the Bible that gave him a new understanding of faith.
The document discusses using Groasis Waterboxx devices to help plant and grow trees in dry environments like the Sahara Desert. It describes how the author and a colleague tried using 10 Waterboxx devices to plant trees in M'hamid, Morocco but their luggage containing the devices was initially lost. They were eventually found and the devices were used to plant tamarisk trees to compare growth with traditional planting methods. The document provides details on how the Waterboxx works, collecting condensation and directing water to tree roots, and hopes the experiment will help increase tree survival rates in the dry climate.
The Groasis Waterboxx is a low-tech device that helps seeds and saplings grow into strong trees in dry environments. It collects and stores rainwater and condensation to slowly water the roots daily. In tests, 88% of trees grown with the Waterboxx survived compared to only 10.5% without it. The inventor believes using this technology could reforest billions of acres and offset humanity's carbon emissions by capturing CO2 in new tree growth.
The document discusses the Groasis Technology, a planting method that uses a Waterboxx and other techniques to plant trees in dry areas with 90% less water. It summarizes that the technology (1) improves soil, maps planting areas, harvests rainfall, and uses the right planting techniques to help trees grow deep roots in the first year to survive independently. It also describes how the technology terraces slopes to harvest and direct rainfall to trees, uses 3D imaging to map ideal planting lines, and a capillary drill to quickly plant thousands of trees per day.
The document describes the Agua, Vida y Naturaleza Project (AVNP) that started in Ecuador in 2012. It is funded by the Dutch COmON Foundation to help small farmers in dry areas by introducing the Groasis Technology, which allows planting in deserts and eroded lands. The technology mimics nature by improving soil, maintaining capillary structures, and using a waterboxx device. The project aims to address issues small farmers face like lack of water, capital, and farming knowledge, in order to help alleviate world hunger and prevent farmers from migrating to cities due to lack of income from farming dry areas.
The document provides planting instructions for using a Waterboxx planting device. It outlines 6 main steps:
1. Preparing the soil by digging holes and adding compost/fertilizer or just watering.
2. Assembling the Waterboxx by placing the wick, mid-plate, lid, and siphons.
3. Preparing plants by pruning roots to encourage deep growth.
4. Planting in holes aligned east-west within the Waterboxx hole.
5. Placing the assembled Waterboxx over the planted area.
6. Watering the plants and filling the Waterboxx for the first time.
This document provides instructions for growing vegetables using the Groasis Waterboxx system. It details recommendations for greenhouse design, soil preparation, planting methods, plant spacing, watering schedules, and pest and disease management. Proper installation and maintenance of the Waterboxx system is emphasized to ensure healthy plant growth and high crop yields. Close monitoring of climate conditions and plant needs is also advised.
The document is a report on the Groasis waterboxx, a device that aims to allow farming without irrigation. It provides an overview of the waterboxx's history and development, describes its components and how it works, reviews testing that has been done, and evaluates its suitability for organic farming. In the conclusion, the report recommends that the cooperative discussed in the document not use the waterboxx yet, as more data is still needed, but could consider conducting their own tests with support from their technical services.
The document summarizes an invention called the Groasis that helps plants survive in arid climates by collecting and storing rainfall to provide steady watering to seedlings. It notes that most rainfall in deserts occurs within one week but is then unavailable, and that the Groasis uses evaporation-proof containers and wicking to deliver water to young plants over longer periods, allowing their roots to develop and access deeper groundwater reserves. Large-scale projects have used the Groasis in countries like Kenya to aid reforestation efforts and combat desertification.
The document summarizes the work of the Sahara Roots Foundation in Morocco and their use of the Groasis Waterboxx to help plant trees and reduce desertification. The Sahara Roots Foundation was established to implement development projects to conserve the Moroccan Sahara through activities like tree planting, irrigation, education, and desert cleaning. They have started using the Groasis Waterboxx, an "intelligent water battery" developed by AquaPro, to improve the survival rate of newly planted trees. The Waterboxx produces and captures water through condensation and rain, allowing trees to be planted in dry areas like rocks and deserts with a 100% success rate.
The document describes the Agua, Vida y Naturaleza Project (AVNP) that started in Ecuador in 2012. It is funded by the Dutch COmON Foundation to help small farmers in dry areas by introducing the Groasis Technology, which allows planting in deserts and eroded lands. The technology mimics nature by improving soil, maintaining capillary structures, and using a waterboxx device. The project aims to address issues small farmers face like lack of water, capital, and farming knowledge, in order to help alleviate world hunger and prevent farmers from migrating to cities.
Groasis Technology is compared to drip irrigation over a 50-year project for a 500-hectare tree plantation. Key financial indicators show that using Groasis Waterboxes results in a higher net present value (NPV) of €26.62 million compared to €21.15 million for drip irrigation, and a slightly higher internal rate of return (IRR) of 22.1% versus 23.4% for drip irrigation. Waterboxx also has a longer payback period of 7 years compared to 5 years for drip irrigation. The document provides assumptions and calculations for costs and revenues for both systems over the 50-year period.
A new technology called the Groasis Waterboxx shows promise for reclaiming desert landscapes and increasing plant survival rates. The simple device regulates temperature and moisture levels around young plants, allowing trees and crops to grow with little watering even in dry conditions. Initial trials in Africa found tree survival rates increased to 88% with the Waterboxx compared to only 10% without it. Researchers in Kenya are optimistic this technology could significantly reduce desertification and help transform the country's deserts into productive, economic areas through increased vegetation.
More from School Vegetable Gardening - Victory Gardens (20)
हिंदी वर्णमाला पीपीटी, hindi alphabet PPT presentation, hindi varnamala PPT, Hindi Varnamala pdf, हिंदी स्वर, हिंदी व्यंजन, sikhiye hindi varnmala, dr. mulla adam ali, hindi language and literature, hindi alphabet with drawing, hindi alphabet pdf, hindi varnamala for childrens, hindi language, hindi varnamala practice for kids, https://www.drmullaadamali.com
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
Discover the Simplified Electron and Muon Model: A New Wave-Based Approach to Understanding Particles delves into a groundbreaking theory that presents electrons and muons as rotating soliton waves within oscillating spacetime. Geared towards students, researchers, and science buffs, this book breaks down complex ideas into simple explanations. It covers topics such as electron waves, temporal dynamics, and the implications of this model on particle physics. With clear illustrations and easy-to-follow explanations, readers will gain a new outlook on the universe's fundamental nature.
Assessment and Planning in Educational technology.pptxKavitha Krishnan
In an education system, it is understood that assessment is only for the students, but on the other hand, the Assessment of teachers is also an important aspect of the education system that ensures teachers are providing high-quality instruction to students. The assessment process can be used to provide feedback and support for professional development, to inform decisions about teacher retention or promotion, or to evaluate teacher effectiveness for accountability purposes.
This presentation was provided by Steph Pollock of The American Psychological Association’s Journals Program, and Damita Snow, of The American Society of Civil Engineers (ASCE), for the initial session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session One: 'Setting Expectations: a DEIA Primer,' was held June 6, 2024.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
9. Disturbing Statistics
• Between 1973 and 1999 Cancer deaths increased 30% (17.7% -23% of
population)
• For the first time (2005), cancer has surpassed heart disease as the top killer
of Americans under 85….” (Los Angeles Times, Jan. 19, 2005
• 1.3 million diagnosed and 570,000 die annually in US
• In the 25-35 year old age group a recent analysis of the National Cancer
Institute statistic showed that survival rates have not increased at all since
1975
“Cancer is the leading disease killer in people age 20 to 39…..more than
70,000 young adults get cancer every year……”
The Wall Street Journal, July 5, 2005, page D1
10. No Refined Carbohydrates!
“Fuel for the Fire”
• 2001 US per Capita Consumption: 170 lbs/year
• 1820 US per capita Consumption: 10-20 lbs/year
11. Sugar = Insulin
• Cancer Cells have 6-15 X Insulin Receptor
Sites
• Insulin Directs Inflammatory Eicosanoids
Pathways
12. “The Metabolism of Carcinoma Cells”
by Otto Warburg
The Journal of Cancer Research
Volume 9, pg 148-163 (1925)
16. CANCER & CLA
•1996 Study of 4,697
Women: The More Whole
Fat Milk in the Diet (More
CLA) = Lower Risk of
Breast Cancer. Women
Drinking the Most Milk
Had a 60% Lower Risk of
Breast Cancer
•Rats Fed 1.5% of
Calories as CLA = Tumor
Size Reduced 60%
•Dr. Tikal Dhiman at Utah
State University: One Can
Lower Cancer Risk by
Consuming Daily, One
Ounce of Cheese, One
Serving of Grassfed Meat
& One Glass of Whole
Milk From Pastured
Cattle.
19. Resveratrol
“Of All the Plants We’ve Tested For Cancer Chemo- Preventive Activity, and The
Compounds We’ve Seen, This Has the Greatest Promise”
(University of Illinois-Chicago)
• Significantly Reduce Tumor Volume (42%), Tumor Weight (44%) and
Metastasis (56%) in Mice w/Highly Metastasized Lung Cancer
• Induced Apoptosis in Human Leukemia Cells; Stopped Growth of
Lymphocytic Leukemia
• Inhibits NF-kB
• Anti-Cancer For Hormone Dependent and Independent Breast Cancers
• Inhibits COX-2
• Restored Glutathione
• Increase Levels of Phase II Detoxification (Quinone Reductase)
• Dose: 20-50-mg/Day
20. CURCUMIN
• Increases Production TGF-beta (Transforming Growth Factor)
Producing Apoptosis
• Increases Expression of Nuclear p53 Protein in Basal Cell Carcinomas,
Hepatomas & Leukemia, Producing Apoptosis
• Inhibits PTK (Protein Tyrosine Kinases) and PKC (Protein Kinase C),
Which Relay Chemical Signals for Proliferation, Metastases,
Angiogenesis, Differentiation, Avoidance of Apoptosis
• Inhibits COX-2
• Inhibits Nuclear Factor-Kappa B (NF-kB)
• Dose 900 mg Capsules 1-3x/Day
22. Carotenoid Study
25,802 Adults in Maryland
• High Levels of beta carotene & alpha
tocopherol = decreased cancer risk
• Persons with highest tier of total
carotenoids = 66% reduction in cancer risk
versus lowest tier
Cancer Res 1993 Feb 15; 53(4): 795-8
23. Vitamin D (Cholecalciferol)
• “Potential impact far greater than influenza
vaccine”- Dr. Scott Dowell (US CDC
11/26/06- Baltimore Sun)
• Vitamin D produces anti-biotic peptides via
white cells
• 200,000 IU’s for (3) days
• Ideal Blood Levels 25 hydroxy vitamin D:
70-80 ng/mL
24. Cancer Risk Reduction & Vitamin D Status
Cancer
Risk Reduction with
Increased Vitamin D Intake
Breast 50%
Colon 50%
Prostate 49%
Ovary 36%
Recent Results Cancer Res. 2007. 174:225-34; J. Steroid
Biochem Mol Biol. 2007 Mar; 103 (3-5); 708-11; J Steroid
Biochem Mol Biol. 2005 Oct; 97(1-2):179-94; Cancer Res. 2005
June 15; 65 (12); 5470-9; Cancer Epidemial Biomarkers Prev.
2004 Sept. 13 (9): 1502-8.
25. Vitamin D Cancer Mechanisms
• Affects at least 200 human genes, including those
controlling
– Proliferation
– Differentiation
– Apoptosis
– Angiogenesis
– Metastasis
• 89 identified studies showing vitamin D intake reduces
cancers of breast, prostate, colon, esophagus, pancreas,
ovary, rectum, bladder, kidney, lung and uterus – Life
Extension October 2007
26. American Journal of Clinical Nutrition
2007 Jun; 85(6): 1586-91
“Vitamin D and Calcium Supplementation
Reduces Cancer Risks”
• 1180 Post Menopausal Women
• 1000 IU’s Vitamin D/day for (4) years
– 60% Lower Cancer Risk
– 77% Lower Cancer Incidence when excluding
cancers in first year of study
• Vitamin D & Calcium = best outcomes
27. SELENIUM
• Potentiates Chemotherapy for Prostate & Colon Cancer
• Drew University of Medicine and Science
– Significant Increase in Apoptosis and Decrease in DNA Synthesis in
Cancers of Breast, Lung, Small Intestines, Colon and Liver
• 10 Year Study on 1312 Subjects
– Prostate Cancer Reduced 63%
– Colon Rectal Cancer Reduced 58%
– Lung Cancer Reduced 46%
• Dose: Use Se-Methylselenocysteine: and Selenium Yeast: 400-600
mcg/day. Take with Vitamin E (Tocotrienols and Gamma Tocopherol)
400-800 IU/day
28. IODINE
• Japanese: Lowest Level of Breast, Uterine Ovarian and Prostate Cancer
• Daily Japanese Iodine Consumption: 14-100 mg
• U.S. R.D.A.: 150-200 mcg
• Maintaining Iodine Sufficiency : 13 mg/Day
– 6 mg Thyroid
– 5 mg Breast
– 2 mg Rest of Body
• Displaces Bromine (Carcinogen)
• Chelates Metals and Other Toxins
• Destroys Parasites, Yeast, Bacteria, Virus
• Promotes Stomach Acidity
• Helps Hypo and Hyper Thyroidism
• Prevents, Reverses Hashimoto’s and Grave’s
• Reduces Lipoprotein (a)
• Misc. : Headaches; Parotid Duct Stones; Keloid Formation; Peyronies
Contractures; Breast, Ovarian, & Skin Cysts
29. I3C (INDOLE 3 CARBINOL)
• Inhibits Growth of Estrogen- Receptor Positive Breast Cancer Cells by 90% vs.
Tamoxifen @ 60%
• Stops Human Cancer Cells From Growing (54-61%) and Initiated Apoptosis
• Increases Conversion of Estradiol to Estriol by 50% in (1) Week (12 Subjects)
• Prevented Aflatoxin Induced Liver Cancer, Leukemia, Colon Cancer &
Chemically Induced Breast Cancer 70-96% (Lab Rats)
• Restores p21 and Other Proteins That Correct Adducts (Tamoxifen No Effect)
• Hoechst Marrion Roussel: New Generation of Indole Drugs to Replace Estrogen
Drugs
• Dose 200 mg 2-4x / Day As Per Body Wt.
35. CO-Q10 (Ubiquinol)
400-600 mg
• University of Miami
• Significantly reduces expression of bcl-2 gene
(resistance to apoptosis) of cancer cells
• Remission of metastasized breast cancer- 1994
European Study
• Rats on Tamoxifen: 3 X increase in tumor weight
• Rats of Tamoxifen & Co-Q10: No increase in
tumor weight
– Restored SOD, Catalase, Glutathione
36. Vitamin E Complex
800 IU/day
• Need all tocopherols (alpha, beta,
gamma delta)
• Inhibit cycloxygenase 2 (COX)
enzyme
• Neutralizes reactive nitrogen oxides
• Reduces oxidation of LDL and fats
• Reduces Leukotrine b4 and TNF-@
• Finnish study of 29,000 PC patients
(smokers) for 5-8 years: 32%
decrease; 40% decrease in mortality
37. Vitamin A
100,000-300,000 IU/day
• Secretory IgA = Immunity of
Mucosal Tissue
• 14 month trial, 181 patients with
post-surgical non-small lung cancer
– 300,000 IU/day
– Relapses: 18% vs 28% (controls)
• After 46 months, rates of tumor
reoccurrence/new tumors
– 37% (treated) versus 48% controls
Journal of Clinical Oncology
1993; 11(7): 1216-22
38. Green Tea
• Polyphenols (Epigallocatechin gallate EGCG)
• Elevates Caspase 3 Enzyme (Apoptosis)
• Inhibits Invasilon
• Inhibits metastasis
• Stimulates Immunity
• Free Radical Scavenger (greater than Vitamin E)
– E.g. Mice with melanoma & lung carcinoma cells-
number of tumors decreased 50% and 29%
• Inhibits interaction between estrogen and estrogen
receptors (prostate and breast cancer)
39. ARTEMINISIN
Artemisia Annua or Sweet Wormwood
• University of Washington Drs. Henry Lai and Narerida Singh
• Int’l Journal of Oncology 18; 767-773, 2001
• Peroxide Linkage Attacks “Free” Iron (Cancer and Malaria)
– Releases Free Radicals; Destroys Cells
• All Cancers Respond- No resistance!
• Active Ingredients
– Artesunate: Water Soluble, Most Active, Shortest Half Life
– Artemisinin: Intermediate Half Life
– Artemether: Fat Soluble, Most Toxic, Longest Half Life
• 500 mg Twice Daily on Empty Stomach w/ Whole Milk or Cod Liver Oil (Fat)
• Take for (2) Years
Nutricology
800-545-9960
www.nutri-cology.com
41. Proceedings of National Academy of Science USA
Volume 73, No. 10 pp 3685-3689 October 1976
by E. Cameron and L. Pauling
• All Patients were determined to be terminal;
ascorbate only administered to
“untreatable” patients
– Treated Group: 10 grams ascorbate I.V. for 10
days; orally thereafter
– Matched Controls: No Treatment
42. Average Survival Times and ratios for Ascorbate & Matched Controls
A
Type of Cancer (X)
# of ascorbate
B
Ascorbate
(Days)
C
Control
(Days)
D
Ratio
B/C
E
Ave Day
survival
both goups
F
%
Ascorbate
surviving >
E
G
% Controls
Surviving >
E
Bronchus (15) 136 38.5 3.53 47 47 8.7
Colon (13) 282 37 7.61 59 54 20
Stomach (13) 99 38 2.61 43 46 19
Breast (11) 367 64 53-.75 91 55 22
Kidney (9) 333 64 5.21 88 67 22
Bladder (7) 196 43.6 4.49 57 57 20
Rectum (7) 226 55.5 4.10 71 86 33
Ovary (6) 148 71 2.08 78 83 30
Others (19) 172 56.8 3.03 67 53 27
All (100) 209 50.4 4.16 65 60 25.7
16% of Ascorbate patients survived in excess of (1) year, vs. 0.3% of controls (53X)
44. Difference in Average Survival Times of Ascorbate-Treated Patients & Matched Controls
Primary
Tumor Type
Patient No.
Test Control
From First Hospital
Attendance
A B
Test Control
From Date of
Untreatability
C D
Test Control
Increased Survival Times
of Ascorbate Treated
patients, days
E F
A-B C-D
Colon 17 170 458(+) 316 352(+) 33 142(+) 319(+)
Bronchus 17 170 219(+) 118 186(+) 31 101(+) 155(+)
Stomach 13 130 286(+) 159 182(+) 32 127(+) 150(+)
Breast 11 110 1369(+) 1020 487(+) 52 376(+) 435(+)
Kidney 8 80 774(+) 492 38(+) 39 282(+) 342(+)
Bladder 7 70 1669(+) 420 355(+) 21 1249(+) 334(+)
Rectum 7 70 634 336 270 43 298 227
Ovary 6 60 884 366 183 69 518 114
Other 14 140 706(+) 279 278(+) 37 427(+) 241(+)
All 100 1000 681(+) 360 293(+) 38 321(+) 255(+)
Mean Survival Times, Days
(+) indicates one patient in group
survived after May 15, 1978
45. The Center for the Improvement of
Human Functioning
The Late Dr. Hugh Riordan (M.D.) Founder 1975
Wichita, Kansas, 67219 (RECNAC)
www.brightspot.org (316) 682-3100
•20 Published papers on Vitamin C & Cancer
•RECNAC II University of Puerto Rico
“Orthomolecular Oncology Review: Ascorbic Acid &
Cancer 25 Years Later”
46. Ascorbate Findings by RECNAC
• Animals synthesize Vitamin C from glucose
in only (4) metabolic steps
• Cancer cells readily absorb and accumulate
ascorbate (similar to glucose molecule?)
Vitamin CGlucose
47. • At adequate concentrations (400+ mg/dl)
Vitamin C is selectively toxic to cancer cells
• Vitamin C behaves as pro-oxidant
– Interacts with intracellular Fe & Cu
– Reaction produces H2O2
– Cancer cells are deficient in catalase
Ascorbate Findings by RECNAC
48. IV Vitamin C Boost Immunity
Ascorbate Findings by RECNAC
49. • IV Vitamin C inhibits hyaluronidase
• IV Vitamin C Corrects scurvy in Cancer Patients
• IV Vitamin C induces apoptosis
• IV Vitamin C reduces pain
• IV Vitamin C neutralizes chemo and radiation
toxicity without neutralizing their cancer killing
effects
• IV Vitamin C helps cancer patients recover faster
from treatments and disease
Ascorbate Findings by RECNAC
51. IV Vitamin C
Stimulates Collagen
Formation Via
Hydroxylation of
Proline
Ascorbate
Findings by
RECNAC
52. Benefits of Additional Vitamins
• Adding Vitamin B-12 create cytotoxic
cobalt ascorbate
• Adding Lipoic Acid “recycles” ascorbate to
maintain plasma saturations and increase
sensitivity of cancer cells to ascorbate
• Adding Vitamin K-3 (menadione) recycles
DHA (Dihydro ascorbate)
53. RECNAC Vitamin C Case Histories
52 year old female- Renal Cell Carcinoma
• Diagnosed 9/95
• 9/96- (8) 1-3 cm lung metastasis
– No prior treatment
– 10/96 IV Vitamin C- 65 gms bi-weekly plus NAC, beta
1,3 glucan, fish oil EPA, vitamin C (9 gms/day), beta-
carotene, L-threonine, niacin, chromium, Bacillus
laterospores
• Treatments until June 1997. 7 masses resolved.
Large reduction of 8th mass.
• Four years later (2001), no evidence of
progression
54. 70 Year Male- Renal Carcinoma
• Diagnosed 12/85
• Radical nephrectomy; Xrays/CT: multiple
pulmonary & liver lesions. No chemotherapy
decided
– March 1986- IAA, 30 gms 2X/week
– April 1986 (6 weeks treatment): complete resolution of
lung, liver and lymph node metastasis
– 1986: 30 gms IAA 2X/week for 7 months; reduced to
1X/week for 8 months; reduced to 15 gm IAA 1X week
for six months
– Patient expired 12 years later, cancer free at age 82
RECNAC Vitamin C Case Histories
56. Cimetidine
The Lancet, 1979 (pp. 822-823) USA
• University of Nebraska- Two Patients
1. Squamous cell carcinoma metastasis to lung
2. Non small cell lung cancer metastasis to brain
1. 1200 mg/day Cimetidine for stomach distress
• Reduced to 600 mg/day cimetidine
• One year later, no detectable tumor
2. 600 mg/day Cimetidine & steroids (brain swelling)
• Brain tumor excised, one year later no long tumor
57. The Lancet 1982ii (p 328) Ireland
• Four Stage IV Melanoma patients (mets to
liver and lung)
– 1000 mg/day Cimetidine & Coumadin
– Three patients: dramatic remissions
– One patient: death
– All four patients had T-suppressor cells
decreased by Cimetidine
58. New England Journal of Medicine
1983, Vol. 308, pp 591-592 Sweden
• Cimetidine
– Six Melanoma Patients (Interferon &
Cimetidine)
• 2 complete remissions
• 1 partial remission
• 1 progression arrested
• 2 deaths
59. The Lancet
December 31, 1994 pp 1768-1769 Australia
• Cimetidine given (7) days only at time of
surgery
• Three year survival
• Cimetidine: 93% (T-cell infiltration into tumors:
63%)
• Controls: 59% (T-cell infiltration into tumors:
24%)
60. The Lancet (Colorectal Cancer)
Dec 24-31, 1994; 344 (8939-8940)
• Cimetidine given for 5 days pre & 2 days
post operative
• Decrease 3 year mortality rate from 41% to
7%
61. British Journal of Cancer
2002 (86) 161-167
• Dukes Grade C Aggressive Colon Caner
• 10 Year Study with 15 Japanese Institutions
– Treated patients given 800 mg Cimetidine/day for
12 months
– Treated 10 year survival rate: 84.6%
– Control 10 year survival rate: 23.1%
62. The Lancet
December 12, 1987 pp 1371-1374 European Stroke
Prevention- Two year study
– No benefits from Aspirin Alone
– With Dipyridamole: Stroke reduced 50%,
myocardial infarction reduced 38%, cancer
reduced 30%
– Boehringer Ingelheim (original patent holder): no
longer advise M.D.’s that dipyridamole prevents
cancer cells from attaching to vascular system
(metastasis)
Dipyridamole
63. The Lancet
March 23, 1985 p 692
Dr. E.H. Rhodes, St. Hiler and Kingman Hospital in
Surrey, England
• 30 Melanoma Patients
– 300 mg/day Dipyridamole: 11 year study
• 26 patients: Stage IV
– 5 year survival = 74%
– English Average = 32%
• 4 patients: Stage III
– 5 year survival = 100%
64. The Lancet
October 17, 1964 Canada
pp 832-835
“Cancer Incidence and Mortality in Patients Having
Anticoagulant Therapy”
• L. Michaels (student of O.Meara) studied 1500
“patient years” of patients on Coumadin
– Statistical expectation of 8 deaths from cancer
– Only 1 death detected (lung cancer)
65. New England Journal of Medicine
February 25, 1982 p. 484 Sweden
Bjorn Stenkvist M.D., University Hospital, Uppsala, Sweden
Digitalis
• 149 Breast Cancer Patients
• 40 on Digitalis
– 34 Digitoxin
– 6 Digoxin
• 109 Controls
• 5 year outcomes
– Digitalis Patients: 1 re-occurrence (2.5%)
– Controls: 21 re-occurrences (19.25%)
• Observation: Digitalis made breast
cancer cells smaller and more uniform
66. Medical Hypotheses 1999 53 (6)
Johan Haux M.D. Institute of Cancer Research and Molecular
Biology, Norwegian University for Science and Technology,
Trondiem, Norway
• Digitalis
– Anti-Cancer effect of digitalis is induction of
apotosis
– Digitoxin (natural) has greater anti-cancer effect
than digoxin (synthetic)
– Effective for Glioblastoma
– Cost is < $2.00/day!
76. Center for the Study of Natural Oncology
Vince Gammill N.D.
vgammill@adelphia.net
858-523-9144
San Diego Clinic
Filiberto Munoz M.D.
Tijuana, Mexico
619-804-7783
77. Resources
• Weston A. Price Foundation
www.westonaprice.org
• Life Extension Foundation www.lef.org
• People Against Cancer (Ralph Moss)
www.peopleagainstcancer.com
• Cancer Control Society
• www.preventcancer.com (Dr. Samuel
Epstein)