This document discusses the poor state of American health and links it to the standard American diet high in processed foods, sugar, and refined carbohydrates. It notes the rise of fast food consumption and obesity rates. Several studies are cited showing the traditional diets of other populations have higher nutrient density and lower rates of diseases like heart disease and cancer compared to the modern Western diet. Grass-fed animal products and traditional diets contain higher levels of beneficial fatty acids like CLA and omega-3s that may protect against cancer, weight gain, and inflammation.
Plant-based Eating: Enhancing Health Benefits, Minimizing Nutritional RisksRobin Allen
Learning Objectives
At the end of the session, the participants will be able to:
1. Know there is no single definition of a plant-based diet.
2. Discuss health aspects of vegetarian and vegan diets and quality of evidence supporting health claims.
3. Assess nutritional adequacy/status of vegetarians and/or vegans throughout the life cycle and provide strategies for meeting dietary recommendations for vitamin B12, DHA calcium, and zinc.
Lifestyle Medicine: The Power of Personal Choices, North American Vegetarian...EsserHealth
Learn about the leading chronic diseases in America and how Lifestyle Medicine can radically shift the burden of disease in your life and western society at large.
Plant-based Eating: Enhancing Health Benefits, Minimizing Nutritional RisksRobin Allen
Learning Objectives
At the end of the session, the participants will be able to:
1. Know there is no single definition of a plant-based diet.
2. Discuss health aspects of vegetarian and vegan diets and quality of evidence supporting health claims.
3. Assess nutritional adequacy/status of vegetarians and/or vegans throughout the life cycle and provide strategies for meeting dietary recommendations for vitamin B12, DHA calcium, and zinc.
Lifestyle Medicine: The Power of Personal Choices, North American Vegetarian...EsserHealth
Learn about the leading chronic diseases in America and how Lifestyle Medicine can radically shift the burden of disease in your life and western society at large.
CardioTabs nutritional supplements are developed by leaders in the field of preventive cardiology to provide you with the right nutritional support for a healthy heart.
We all know about the seriousness of cancer. Diet plays an important role in causing, preventing and treating cancer. Let’s take a look at some of the most common cancer-causing and anti-cancer foods.
This is my latest powerpoint that I use when sharing the nutritional info behind the sea vegetables and aloe that I drink. I am so glad I decided to learn more about this and share it with others. So many lives have been changed in health and finances because of my decision to take a look. My sister did not get gestational diabetes this time in her 3rd pregnancy...the only pregnancy that she was taking the supplement. She went from skeptic to believer. Others with thyroid issues have been able to lessen their meds and people that were told they would have to live with things for the rest of their lives are finding that they do not. This has truly been rewarding helping others. It has also given me a stay at home income that has been a great help to my family in these harsh economic times. We went from our house being on the market as a short-sale to keeping our home and having more than we need...which enables us to help others instead of needing help. What a blessing this has been in our lives. Take a look. It is hard to get the full description without a narrator, but you can pick up a few things. For more explanation you can email me at blessedgirl1973@me.com.
God bless!
The purpose of this presentation is to help people make more informed choices of food and beverages, leading to a reduction in the overall consumption of animal products!
Mayo Dressing
This is part of Budwig Protocol proposed to cure cancer developed by Dr. Budwig.
Delicious mayo salad dressing can be prepared by mixing together 2 Tbsp (30 ml) Flax Oil, 2 Tbsp (30 ml) milk, and 2 Tbsp (30 ml) cottage cheese. Then add 2 tablespoons (30 ml) of Lemon juice (or Apple Cider Vinegar) and add some herbs of your choice.
CardioTabs nutritional supplements are developed by leaders in the field of preventive cardiology to provide you with the right nutritional support for a healthy heart.
We all know about the seriousness of cancer. Diet plays an important role in causing, preventing and treating cancer. Let’s take a look at some of the most common cancer-causing and anti-cancer foods.
This is my latest powerpoint that I use when sharing the nutritional info behind the sea vegetables and aloe that I drink. I am so glad I decided to learn more about this and share it with others. So many lives have been changed in health and finances because of my decision to take a look. My sister did not get gestational diabetes this time in her 3rd pregnancy...the only pregnancy that she was taking the supplement. She went from skeptic to believer. Others with thyroid issues have been able to lessen their meds and people that were told they would have to live with things for the rest of their lives are finding that they do not. This has truly been rewarding helping others. It has also given me a stay at home income that has been a great help to my family in these harsh economic times. We went from our house being on the market as a short-sale to keeping our home and having more than we need...which enables us to help others instead of needing help. What a blessing this has been in our lives. Take a look. It is hard to get the full description without a narrator, but you can pick up a few things. For more explanation you can email me at blessedgirl1973@me.com.
God bless!
The purpose of this presentation is to help people make more informed choices of food and beverages, leading to a reduction in the overall consumption of animal products!
Mayo Dressing
This is part of Budwig Protocol proposed to cure cancer developed by Dr. Budwig.
Delicious mayo salad dressing can be prepared by mixing together 2 Tbsp (30 ml) Flax Oil, 2 Tbsp (30 ml) milk, and 2 Tbsp (30 ml) cottage cheese. Then add 2 tablespoons (30 ml) of Lemon juice (or Apple Cider Vinegar) and add some herbs of your choice.
Wheat grass is an important detoxifying juice therapy that eliminates toxins from the body and improves cell activity. Thus the disease affected cells rejuvenate and make the body healthy. Try one for yourself, Even cancer is cured with Wheat grass juice.....it credits to the discovery of medicinal properties of Wheat grass..
We all want to feel alive and energetic, look forward to each new day and enjoy optimum health. To accomplish this, each of us must assume responsibility for our own well-being. Food is vital to our health. It provides the building blocks for growth and repair, and fuel for energy. It is a key element in the length and quality of life.
The objective of this presentation is to give you a basic understanding of nutrition, to help you decide which foods are the best to select, to inform you of the harmful foods which cause disease, and beneficial foods which helps prevent disease.
Donna Weihofen, retired Senior Nutritionist spoke about Eating the Mediterranean Way at Wisconsin Women's Health Foundation's 2013 annual Gathering in Marshfield, WI. The Mediterranean diet emphasizes:
• Eating primarily plant-based foods, such as fruits and vegetables, whole grains, legumes and nuts
• Replacing butter with healthy fats, such as olive oil
• Using herbs and spices instead of salt to flavor foods
• Limiting red meat to no more than a few times a month
• Eating fish and poultry at least twice a week
• Drinking red wine in moderation (optional)
Dr. Alap Shah from La Grange Family Medicine Residency of Amita Health talks about the importance of plant-based nutrition and tips on billing for it at the 2019 Family Medicine Midwest educational meeting
All too often we hear nutrition myths. They confuse many people and result in personal choices that compromise health and increase the risk of disease. In this powerpoint, Dr Esser reviews some foundational and a few specific myths and presents compelling science to set the record straight. Enjoy and remember to keep on asking questions and learning how you can achieve your best health in 2018.
How to prevent heart disease and diabetesEsserHealth
Heart disease is the leading cause of death in men and women in America today. Learn how the food you eat can radically alter your risk of both heart disease and type two diabetes. You can achieve better health starting today.
Organic Edible Schoolyards = Academic Success + Healthy Students
INCLUDES LINKS TO:
Over 80 books and web sites dealing with Gardening with Children - Over 300 books on Organic Gardening - Over 200 books on Sustainable Technology - Over 50 books on Renewable Energy - Many Free PDF files on Rain Gardens, Roof Gardens, Aeroponic Gardening, Rainwater Harvesting, Waterwise Gardening, Green Eco Churches, Vegetable Oil Cars, Organic Gardening Guides, Ram Pumps, Companion Planting, 7 - Garden Therapy Manuals
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
2. American Health & Vitality
• Ranked #24 in Healthy Life Expectancy
• Ranked #8 in Women’s Life Expectancy
• Ranked #15 in Men’s Life Expectancy
• Ranked #20 in Infant Mortality
3. The Dark Side of the
All-American Meal
1970: $6 Billion
2000: $110 Billion
More than autos,
computers and college
education
4. Fast Food Nation
• Americans Eat 1/5 of Their Meals in Cars
• Americans Feed 1/3 of Their Children Daily in Fast
Food Restaurants
• N.I.H. Diabetes Forecasts on Children Born 2000-
“The Class of 2018”
– 35% Caucasian
– 40% African-American
– 52% Hispanic
• 2008- 25 Million Diabetics
• 2050- 50 Million Diabetics
• 2000- 60-75 Million “Syndrome X”
Will Contract Type II Diabetes
(A.K.A. Adult Onset Diabetes)
5. THE AGE OF DIABETES *
• 23.6 million (7.8% U.S. population)
• 5.7 million Undiagnosed
• 57 million have “pre-diabetes” (Syndrome X)
• 1.6 million New Cases Yearly
*www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf
*Diabetes Care, 32 (2009): 513-561. PMID 19118286
9. March 24, 2004
“That which is
lacking in the
Present World is
a profound
knowledge of
the Nature of
Things.”
Frithjot Schuon
Diagnosis = 41% of all Americans
Mortality = 20% of all Americans
10. More People Make
Their Living From
the Cancer Industry
than Die From
Cancer
Annual Cost of Treating
Cancer
Estimated $150 billion
• 99% of Research Funds
Primary Tumors, Not Metastatic
Illness
17. American Diet
15-25 (LA):1 (ALA)Omega 6
(Linoleic Acid)
Omega 3
(Alpha Linolenic Acid)
Desaturase
Elongase
Desaturase
ArA
EPA (5% of ALA)
E/E/D/B-ox
DHA (1% of ALA)
18. INFLAMMATORY CYTOKINES
(Vioxx or Celebrex??!!)
• Result of Excessive Insulin (Sugar!)
• Result of Excessive Omega 6’s (Grain)
• Result of Deficiency of Omega 3’s
19. ANALYSIS OF ARTERIAL
PLAQUE FAT
•25% fat is saturated
•75% fat is polyunsaturated
•Heart attack incidence in 1900 was a fraction of 2002
but blood cholesterol has remained constant
20. National Institute of Health
• Mr. Fit Trial (1982)
• Lipid Research Clinic Trial (1984)
No Association Between Fat and Heart Disease!
Steinberg D . “Thematic Review Series: The Pathogenesis of
Atherosclerosis, An Interpretive History of the Cholesterol
Controversy: Part II: The Early Evidence Linking
Hypocholesterolemia to Coronary Disease in Humans” J Lipid Res
46:2 (2005) 179-190
21. The Framingham Heart Study
Reviews of 26 Years
• 80% of Heart Attack Patients Had Similar
LDL Levels of Those Who Did Not Have
Heart Attacks
• 2X as Many Individuals with Lifetime Total
Cholesterol of <200 mg/dl had Heart
Disease Compared to Those with Total
Cholesterol of >300 mg/dl
Castelli, W.P. et. al. “HDL Cholesterol and Other Lipids in Coronary Heart
Disease. The Cooperative Lipoprotein Phenotyping Study” Circulation 55
(1977): 767-772
22. The Caloric Myth: A Calorie is a Calorie
Fat: 400 Calories
Protein: 800 Calories
Total: 1200 Calories
Carbohydrates: 400 Calories
Protein: 800 Calories
Total: 1200 Calories
50% to lose 40 lbs
@ 1-5 lbs/week
1% to lose 40 lbs
@ 1-5lbs/week
23. Glycemic Index Versus Glycemic Load
Source Volume
Glycemic
Index
Glycemic
Load
Pasta 1 cup 59 3,068
Apple 1 cup 54 972
Broccoli 1 cup 50 150
From: The New Glucose Revolution by Jenna Brand-Miller,
Thomas Wolever, Kaye Foster-Powell and Stephen Colaqiuri
(Marlowe & Co., 2002)
24. Percentage of Essential Fatty Acids in
Human Body Fat
(1991-1992)
Society %
Omega–6
%
Omega-3
Ratio
New Zealand Maori 2.6 0.93 2.8:1
Japanese 14.8 3.2 4.6:1
American 10.2 0.58 17.6:1
(Source: Erasmus, 1993)
25. PEANUTS LA: ALA
(5000:1)
LA: 15,600 mg/ 100 gms
ALA 3 mg/ 100 gms
WALNUTS LA: ALA
(1:2.4)
LA: 3,800 mg/ 100 gms
ALA: 9,080 mg/ 100 gms
WILD SALMON
EPA: 419 mg/ 100 gms
DHA: 586 mg/ 100 gms
Polyunsaturated Fatty Acids in the Food Chain in the United States. American Journal of Clinical
Nutrition 71: 179-885. Kris Etherton PM, Taylor DS, Yu-Poth S, et. al. 2000
27. DHA
The Longest & Most Unsaturated Omega 3
• Most Concentrated in Brain/Eyes
• Second most concentrated in Sperm
• Third most concentrated in heart muscle
28. BIG PHARMA’S
Anti-Health Campaign
“More Omega-3 Fats Didn’t Aid Heart
Patients” (N Engl. J Med 29 Aug 2010)
• 4800 men/women history of heart attacks
• 40 months on margarine-enriched with
EPA/DHA/ALA
• Margarine considered “placebo”
• Funded by Unilever, et. al.
29. Country Rate Fat in the Diet
Japan 34 Low fat, high fish consumption
France 58.6 High fat, high butter consumption
Italy 94.7 High fat, high olive oil consumption
United States 170
High fat, low fish, butter & olive oil
consumption
Heart Attacks Per 100,000 People
Source: U.S. Department of Commerce, 1996
31. CHOLESTEROL’S VITAL IMPORTANCE
• Necessary to synthesize Vitamin D (needed
for mineral absorption, insulin production,
healthy nerves)
• Synthesis of bile salts
• Production of hormones (anti-stress & sex
hormones)
• Cell membrane elasticity & strength
• Anti-oxidant
• Necessary for brain & nerve development
• Serotonin availability to brain
32. Government officials and
doctors fear that Inuit will
switch to imported
processed foods loaded
with carbohydrates and
sugar, risking
malnourishment,
vitamin deficiencies, heart
disease, diabetes and
obesity. “The level of
contamination is
very high in Greenland,
but there’s a lot of
Western food that is worse
than the poisons,”
In some respects, the
marine diet has made the
Inuit among the world’s
healthiest people.
Beluga whale meat has
10 times the iron of beef,
twice the protein and five
times the Vitamin A.
Omega 3 fatty acids in
the seafood protect the
Inuit from heart disease
and diabetes. Seventy-
year-old Inuit men have
coronary arteries as
elastic as those of 20-
year-old Danes, said
Dr. Gert Mulvad of the
Primary Health Care
Clinic in Nuuk.
LOS ANGELES TIMES
JANUARY 13, 2004
33. Alpha Linolenic Acid (Parent Omega 3)
•Most abundant Fatty Acid on Earth
•The cell membrane of the chloroplast
34. Distribution of Plant Lipids
Leaves: Omega 3 Omega 6
Seeds: Omega 6 Omega 3
Storage Fat
Less Oxidizable
Desaturase enzyme
Cell Membrane
of chloroplast for
photosynthesis
Desaturase enzyme
35. Nutrition and Physical
Degeneration
6th
Edition
Weston A. Price, D.D.S.
With forewords to previous editions by
Earnest A. Hooten, Professor of Anthropology,
Harvard University,
Granville F. Knight, M.D.
and Abram Hoffer, M.D., Ph.D.
36. Nutrients in Traditional Diets
Compared to 20th Century Western Diets (Numbers
Represent Percentage Greater in Traditional Diets)
Calcium Phosphorous Magnesium Iron Fat-Soluble
Vitamins
Eskimo 540% 500% 790% 150% 1,000+%
Swiss 370 220 250 310 1,000+
Gaelics 210 230 130 100 1,000+
Australian
Aborigine
460 620 170 5,060 1,000+
New Zealand
Maori
620 690 2,340 5,830 1,000+
Melanesians 570 640 2,640 2,240 1,000+
Polynesians 560 720 2,850 1,860 1,000+
Peruvian Indians 660 550 1,360 510 1,000+
African (cattle
raising)
750 820 1,910 1,660 1,000+
Africans
(agricultural)
350 410 540 1,660 1,000+
(Source: Price, 1938)
37. Cancer Inversely Related to
Decrease in Diversity
• iKung Bushman (Kalahari Desert) 75(+) plants in
their diet: Cancer virtually unknown
• Hunter-Gatherers (before Agriculture) ate
between 10,000-80,000 Foods Seasonally
• 1900 America Diet
– 100 types of apples
– 50 types of vegetables
– 30 types of meat
• 2006 American Diet
– 5-10 plants
39. CLA RESEARCH
•First Discovered by
Australian Lipid
Biochemist Dr. Peter
Parodi in Early 1980’s
•Continued Research at
University of Wisconsin
by Biochemist Michael
Pariza et. al.
40. CANCER & CLA
•1996 Study of 4,697
Women: The More Whole
Fat Milk in the Diet (More
CLA) = Lower Risk of
Breast Cancer. Women
Drinking the Most Milk
Had a 60% Lower Risk of
Breast Cancer
•Rats Fed 1.5% of
Calories as CLA = Tumor
Size Reduced 60%
•Dr. Tikal Dhiman at Utah
State University: One Can
Lower Cancer Risk by
Consuming Daily, One
Ounce of Cheese, One
Serving of Grassfed Meat
& One Glass of Whole
Milk From Pastured
Cattle.
41. WEIGHT LOSS & CLA
THREE MONTH STUDY: 20
INACTIVE MEN & WOMEN
•Treated Group (3 Grams
CLA/Day vs. Control
(Placebo)
•CLA Group Lost 5 Pounds
& 15-20% Drop in Body Fat
(Lipoprotein Lipase Enzyme
Blocked by CLA)
42. MUSCLE GAIN & CLA
•CLA Group of Men Could
Bench Press 30 Pounds More
in 28 Days
•Control (Placebo) Group
Improved by 9 Pounds
•Enhances Hormone
Sensitive Lipase to Break
Down Fat Already Deposited
in Cells
43. GRASSFED MEAT & MILK HAS 4-5
TIMES MORE CLA THAN GRAIN FED
MEAT: T. DHIMAN PhD, 1996.
44. Botanical Composition of Pastures
Grass
Average
Legume
Average
Compositae
Average
Rosacea
Average
Plantiagnace
Average
Lowlands 52.5% 47.5% 0% 0% 0%
Mountains 63.7% 7.3% 3.1% 2.5% 2.45%
Highlands 40.20% 9.2% 15.6% 5.6% 5.3%
Grams Fatty Acids/100g Fat
Lowlands Mountains Highlands
CLA C18:2c9t11 0.81 1.50 2.18
∑ CLA 0.87 1.61 2.36
C18:1t10(+)t11 2.11 3.66 5.10
∑ Trans Fatty Acids 4.55 6.44 8.44
Conjugated and trans fatty acids in summer milk fat from lowlands, mountains and
highlands (g. fatty acids/100g fat)
Swiss Federal Research Station, Liebefeld, Berne, Switz. 12/8/2000
45. Omega Egg
60 g – large egg
Standard Egg
60 g – large egg
Calories 75.0 75.0
Protein 6 grams 6 grams
Carbohydrate .6 grams .6 grams
Total Fat 6.0 grams 6.0 grams
Saturated Fat 1.5 grams 2.2 grams
Polyunsaturated Fat 1.35 grams .90 grams
n-6 Fatty Acids 750 mg 800 mg
n-3 Fatty Acids 350 mg 60 mg
C18:3 250 mg 40 mg
C22:6 DHA 100 mg 20 mg
n-6:n-3 Ratio 2.6 13.0
Monounsaturated Fats 2.8 grams 2.4 grams
Cholesterol 180 mg 210 mg
Vitamin A 660 i.u. 470 i.u.
NUTRITIVE VALUE OF
OMEGA EGGS
COMPARED TO
STANDARD
EGGS
Lutein
Carotene
Vitamin E
Cysteine
Choline
?
46. Vitamin K1 (Phylloquinone)
• Pre-cursor to activator ‘X’ (K2)
• Found in chloroplast
• Bridge between chlorophyll and iron-sulfur
centers
47. Vitamin K2 (Price’s Activator ‘X’)
Menaquinone
• Converted from K1 by animal tissue
• Butter fat
• Animal fat
• Animal organs
• From livestock on rapidly growing green grass
• Highest percentage from mineralized soils (varied 50 fold
over 20,000 butter samples)
48. Bones & Teeth
Growth
Vitamin A Vitamin D
Matrix Gla Protein
Activated Matrix Gla Protein
Deposition of Minerals
Keeps soft tissues from calcifying
Vitamin A Vitamin D
Osteocalcin
Activated Osteocalcin
Organization of Minerals
Bone Mineralization
Vitamin K2
Osteoblast
Vitamin K2
49. Epigenetics
Modifies the Read-Out of Genes without
Changing DNA
Epigenetics & The Agouti Mice
“Molecular and Cellular Biology” August 1, 2003
•Agouti Mice: Yellow Coats, Extremely Obese
•Predisposed to Diabetes, Heart Disease, Cancer
50. The Agouti Mice Test Group
• Supplemental with Methyl-Group Rich
Supplements
– Folic Acid, Vitamin B-12, Betaine, Choline
• Methylating the DNA Can Modify or
Silence Gene Activity
• Pregnant Mothers Produced Standard, Lean,
Brown Offspring
• Medical (Cancer) Postscript: Only 5% of
Cancer Incidence is Related to Heredity
53. The Necessity of Saturated Fat
• Cell membranes: 50% of Fats in cell
membranes must be saturated for proper
functioning
• Lung function (palmitic acid= 68% Lung
Surfactant)
• Kidney function
• Brain & Nervous System
• Immune System
• Anti-Infective
• Heart/Cardio-Vascular Health
• Vitamin/Nutrient Carrier: A, D, CLA
54. Flavor (and Medicine) is in Fat
• Aromatics (Secondary Plant Metabolites)
are Fat Soluble
• Wild Animals: 30% PUFA’s
• Domesticated Animals: 2% PUFA’s
55. Plant Secondary Metabolites as Defense
• Grazing Animals (tannins,
essential oils, alkaloids)
• Ultra Violet Radiation
• Bacteria, Fungi, Virus
• Defense Against Competing
Plants (walnuts)
• Vulnerable Fruits & Younger
Tissue are higher in PSM’s
56.
57.
58. Organic Milk’s Grass Pigments
(Danish Institute of Agricultural Research)
• 50% More Vitamin E
• 75% More Beta Carotene
• 200-300% More Lutein & Zeaxanthine
• 15 Million Americans have Macular
Degeneration: 10X Increase in 30 Years (Dr.
Paul Beaumont- Macular Degeneration
Foundation
68. Industrialized Agricultural =
Empty Harvest
• Highly soluble acidulated fertilizers leach
nutrients from the soil
• Unprecedented Erosion of Thousands of
Years Worth of Topsoil
• Nutrients become “complexed” and thus
unavailable
69. 450
400
350
300
250
200
150
100
50
1914 1948 1963 1997
Year
(mg.)
Average mineral content in selected vegetables, 1914-1997. Sums
of averages of calcium, magnesium and iron in cabbage, lettuce,
tomatoes and spinach. (Sources: Lindlahr, 1914; Hamaker, 1982;
and U.S. Department of Agriculture, 1963 and 1997)
73. Mean Percent Additional Mineral Content in Organic Compared to Conventional Crops
0
10
20
30
40
50
60
70
80
90
Boron
Calcium
Chromium
Copper
Iodine (498%)
Iron
Magnesium
Manganese
Molybdenum (152%)
Phosphorous
Potassium
Selenium (372%)
Sodium
Vanadium
Zinc
Note: Iodine, Molybdenum and Selenium would go way beyond the 90% increase!
Elevating Anti-oxidant Levels in Food Through Organic Farming
By Charles Benbrook, PhD
74. Carotenoid Study
25,802 Adults in Maryland
• High Levels of beta carotene & alpha
tocopherol = decreased cancer risk
• Persons with highest tier of total
carotenoids = 66% reduction in cancer risk
versus lowest tier
Cancer Res 1993 Feb 15; 53(4): 795-8
78. I3C (INDOLE 3 CARBINOL)
• Inhibits Growth of Estrogen- Receptor Positive Breast Cancer Cells by 90% vs.
Tamoxifen @ 60%
• Stops Human Cancer Cells From Growing (54-61%) and Initiated Apoptosis
• Increases Conversion of Estradiol to Estriol by 50% in (1) Week (12 Subjects)
• Prevented Aflatoxin Induced Liver Cancer, Leukemia, Colon Cancer &
Chemically Induced Breast Cancer 70-96% (Lab Rats)
• Restores p21 and Other Proteins That Correct Adducts (Tamoxifen No Effect)
• Hoechst Marrion Roussel: New Generation of Indole Drugs to Replace Estrogen
Drugs
• Dose 200 mg 2-4x / Day As Per Body Wt.
79.
80.
81. Eating Cruciferous Vegetables
• University of Hawaii: 1600 Men
– Cut Prostrate Cancer Risk 40%
– Cut Colorectal Cancer by 50+%
• Harvard University
– Cut Bladder Cancer by 50%
• Vanderbilt University: China Study
– 50% Reduction in Breast Cancer
85. Glucuronidation
Carcinogens
estrogen
(Liver)
D-Glucarate
Diet
Brussels
Sprouts
Broccoli
Oranges
Grapefruit
Toxins/Estrogen
Conjugated Bile Stool
Beta-glucuronidase
(intestines)
Estrogen/glucarate bondEstrogen re-absorbed
• D-Glucarate inhibited 50% beta-glucuronidase 30% reduction in growth of mammary tumors in promotion stage; four-fold
reduction in number of tumors “D-Glucarate: A Nutrient Against Cancer” by T.J. Siaga, J. Quilici-Timmeke
• D-Glucarate reduced 28% reduction of initiation stage; cell proliferation reduced 42% during promotion state Anti Cancer Res.
1995 May: 15(3): 805-10
• D-Glucarate: 70% decrease in mammary tumor growth Carcinogenesis 1986 Sept: 7(9):1463-6
• Effect of Calcium Gulcarate on beta-glucuronidase activity and glucarate content of certain fruits & vegetables Biochem Med
Metab Biol 1990 Apr.; 43 (2): 83-92
86. Lactoperoxidase
• Works synergistically with Lactoferrin
• Dental Wound Treatment
• Inhibits Human Herpes Simplex Virus-1
• Most abundant enzyme in milk (50 mg/l)
• Heat stable up to 60ºC/30 minutes, or
72ºC/15 seconds
87. SCN¯ + H2O2 OSCN¯ + H2O
Thiocyanates Hydrogen Peroxide Hypothiocyanate Water
(Clover & Brassicas)
Lactoperoxidase
OSCN¯ oxidizes bacterial enzyme (-SH groups)
Hypothiocyanate
Lactoperoxidase Pathway from Soil to Milk
91. Lycopene
40-60 mg/day
• Up Regulates Gene Connexin 43
– Allows intercellular gap communication
• Synergistic with Vitamin D3 (cell
proliferation/differentiation)
• Interferes with growth factor receptor signaling
• Very potent anti-oxidant
• Reduces Insulin-like growth factor- 1 (IGF-1) by
31%
• Prostate, breast, lung, stomach, pancreatic cancers
92. No Refined Carbohydrates!
“Fuel for the Fire”
• 2001 US per Capita Consumption: 170 lbs/year
• 1820 US per Capita Consumption: 10-20 lbs/year
Richard Doll & Richard Peto (Harvard University) “The
Causes of Cancer: Quantitative Estimates of Avoidable
Risks of Cancer in the U.S.” J. Natl Cancer Inst 66:6 (June
1982): 1191-1308.
5 Highest B.C. Mortality = Highest Sugar Consumption
(U.K., Netherlands, Ireland, Denmark, Canada)
5 Lowest B. C Mortality = Lowest Sugar Consumption
(Japan, Yugoslavia, Portugal, Spain, Italy)
93. Sugar = Insulin
• Cancer Cells have 6-15 X Insulin Receptor
Sites- 10 X Insulin Growth Factor Receptor
Sites
• Insulin Directs Inflammatory Eicosanoids
Pathways
94. No Refined Carbohydrates!
“Fuel for the Fire”
• 2001 US per Capita Consumption: 170 lbs/year
• 1820 US per Capita Consumption: 10-20 lbs/year
Richard Doll & Richard Peto (Harvard University) “The
Causes of Cancer: Quantitative Estimates of Avoidable
Risks of Cancer in the U.S.” J. Natl Cancer Inst 66:6
(June 1982): 1191-1308.
5 Highest B.C. Mortality = Highest Sugar Consumption
(U.K., Netherlands, Ireland, Denmark, Canada)
5 Lowest B. C Mortality = Lowest Sugar Consumption
(Japan, Yugoslavia, Portugal, Spain, Italy)
95. Detoxify or Die
by Sherry Rogers, MD
• Average newborns contain 287 pollutants
in blood
• Theo Colburn PhD “Our Stolen Future”
80,000 chemicals in the environment; 15%
have been tested
• Hair Analysis: Analytical Research Labs
Phoenix, AZ
• DMPS Challenge
• RBC Analysis
97. ARE YOU ON FIRE???
• Have Lots of Energy?
• Rested Upon Waking?
• Don’t Crave Carbs?
• Don’t Get Headaches?
• Aren’t Overweight?
• Strong Hair & Nails?
• Clear Minded-Easy to Focus?
• Not Hungry 4-6 Hours Following Meals?
• No Chronic Pain?
• Regular, Soft Bowel Movements
98. IMPORTANT FOODS TO EAT
• Raw (grass fed) Dairy
• Free-Range Eggs
• Cod Liver Oil
• Coconut Oil
• Fermented Soy
Products (miso,
tempeh)
• Fermented Vegetables
• Fermented Milk
Products
• Sprouted Grain
Products
• Pigment Rich
Fruits
• Sea Vegetables
and Ocean Fish
• Vegetables
• Range Fed Meats
• Tropical Fruits
• Pure Water