The document discusses the implications of the exposome paradigm for occupational hygiene. It notes that traditional approaches only examine part of the problem and that new 'omics' tools can provide novel ways to investigate workplace exposures. However, accuracy is not everything and tools need calibration. Tracking location and behavior provides additional exposure data, though confidentiality issues remain. A citizen science revolution in exposure assessment is on the horizon. The document provides resources on the exposome from the National Academy of Sciences, NIOSH, and a primer book. It acknowledges funding from the European Union for the HEALS project on exposure assessment.

1. Where is this all going?
John Cherrie
PDC Session: The exposome and exposure in the workplace

2. Questions…
Ÿ What do you take from this PDC for your own
practice?

3. Some implications for
occupational hygiene…
Ÿ We need to become aware of the exposome
paradigm
Ÿ Traditional diseases are only part of the problem
Ÿ Omics offers new ways to investigate work exposures
Ÿ Accuracy and precision is not everything, but tools
need calibration
Ÿ Tracking location and behaviour provides new data
Ÿ There are confidentiality issues to be resolved
Ÿ Citizen science revolution is coming

4. http://www.niehs.nih.gov/research/supported/dert/programs/peph/podcasts/exposome/
NIEHS…

5. And on YouTube…
https://www.youtube.com/watch?
v=GeYUHUSIniE&list=PLlo0xQLFI54G04vj-H9VdhwbFBL4ANRZv

6. Other resources…
Ÿ US National Academy of Science
Ÿ http://nas-sites.org/emergingscience/
meetings/exposome/workshop-
presentations-the-exposome/
Ÿ NIOSH
Ÿ http://www.cdc.gov/niosh/topics/exposome/
Ÿ The Exposome: a primer by Gary Miller
Ÿ https://www.elsevier.com/books/the-
exposome/miller/978-0-12-417217-3

7. Acknowledgement…
The HEALS project has received funding from the
European Union’s Seventh Programme for research,
technological development and demonstration under
grant agreement No 603946.
Thanks to Sean Semple and Miranda Loh and other
colleagues in the HEALS project for their advice and
assistance in preparing these talks