The document outlines some of the key factors that contributed to the start of the American Civil War, including economic and political differences between the industrial North and agricultural South over the issues of slavery, states' rights, and tariffs. The Missouri Compromise of 1820 and subsequent compromises attempted to balance the number of slave and free states but did not resolve the underlying tensions between the regions. Abraham Lincoln's election in 1860 as the first Republican president was the final trigger for Southern states to secede and form the Confederate States of America.