The document outlines the key events from 1800-1860 that increased tensions between the North and South and ultimately led to the Civil War. It discusses issues such as the Missouri Compromise of 1820, the Fugitive Slave Act of 1850, the Kansas-Nebraska Act of 1854, the Dred Scott decision of 1857, John Brown's raids, and Lincoln's election in 1860 which prompted several Southern states to secede and attack Fort Sumter in 1861, officially beginning the Civil War.