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Topic 3.7 - Cell Respiration
3.7.1. Define cell respiration.
• Cell respiration is the controlled release of energy from organic compounds in cells in the form of
ATP.
3.7.2. State that in cell respiration, glucose in the cytoplasm is broken down by glycolysis into
pyruvate, with a small yield of ATP.
Glucose Glycolysis pyruvate + ATP
3.7.3. Explain that, during in anaerobic cell respiration, pyruvate can be converted in the
cytoplasm into lactate, or ethanol and carbon dioxide, with no further yield of ATP.
• In anaerobic cell respiration in humans, pyruvate is converted into lactate by lactic acid
fermentation. This produces no further yield of ATP.
1
• In anaerobic cell respiration in yeast, pyruvate is converted into ethanol and carbon dioxide during
alcohol fermentation. This produces no further yield of ATP.
3.7.4. Explain that, during aerobic cell respiration, pyruvate can be broken down in the
mitochondrion into carbon dioxide and water with a large yield of ATP.
Aerobic respiration:
• In the presence of oxygen, the pyruvate formed during glycolysis can be used to make as
much as 36 more ATP
• Thus, aerobic respiration is the main source of ATP for cellular functions in eukaryotes
• Pyruvate from glycolysis diffuses from the cytoplasm into the mitochondrial matrix
• In the mitochondria a series of reactions (link reaction, Krebs cycle, electron transport
system, oxidative phosphorylation) oxidise pyruvate to produce ATP
• Byproducts of oxidation include carbon dioxide and water
2

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3.7 respiration notes

  • 1. Topic 3.7 - Cell Respiration 3.7.1. Define cell respiration. • Cell respiration is the controlled release of energy from organic compounds in cells in the form of ATP. 3.7.2. State that in cell respiration, glucose in the cytoplasm is broken down by glycolysis into pyruvate, with a small yield of ATP. Glucose Glycolysis pyruvate + ATP 3.7.3. Explain that, during in anaerobic cell respiration, pyruvate can be converted in the cytoplasm into lactate, or ethanol and carbon dioxide, with no further yield of ATP. • In anaerobic cell respiration in humans, pyruvate is converted into lactate by lactic acid fermentation. This produces no further yield of ATP. 1
  • 2. • In anaerobic cell respiration in yeast, pyruvate is converted into ethanol and carbon dioxide during alcohol fermentation. This produces no further yield of ATP. 3.7.4. Explain that, during aerobic cell respiration, pyruvate can be broken down in the mitochondrion into carbon dioxide and water with a large yield of ATP. Aerobic respiration: • In the presence of oxygen, the pyruvate formed during glycolysis can be used to make as much as 36 more ATP • Thus, aerobic respiration is the main source of ATP for cellular functions in eukaryotes • Pyruvate from glycolysis diffuses from the cytoplasm into the mitochondrial matrix • In the mitochondria a series of reactions (link reaction, Krebs cycle, electron transport system, oxidative phosphorylation) oxidise pyruvate to produce ATP • Byproducts of oxidation include carbon dioxide and water 2