30 September 2014: Synthetic biology applications in defence CDE themed competition
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synthetic biology applications in defence CDE themed competition presentation from 30 September 2014 Innovation Network event in Scotland
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30 September 2014: Synthetic biology applications in defence CDE themed competition
- 1. Synthetic Biology: applications in Defence © Crown copyright 2014 Dstl 01 October 2014 © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 2. Presentation outline • The military context – What we do and how we do it • The problem space • Our interest in Synthetic Biology • The competition © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 3. The military context © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 4. UK Armed Forces • Royal Navy circa 33,000 • British Army circa 82,000 • Royal Air Force circa 36,000 © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 5. © Crown copyright 2014 Dstl 01 October 2014 Another way to look at it… Platforms Logistics Personnel Bases OFFICIAL
- 6. Analysis Systems Weapons CT & Security Human capability C4ISR Integrated survivability CBR Cyber The problem space © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 7. © Crown copyright 2014 Dstl 01 October 2014 Key problem spaces Platforms Logistics Personnel Bases OFFICIAL
- 8. © Crown copyright 2014 Dstl 01 October 2014 Key problem space (1) Personnel • Soldier, platoon • Aircrew challenges • Future soldier? OFFICIAL
- 9. © Crown copyright 2014 Dstl 01 October 2014 Key problem space (2) Platforms • Mobility • Lethality • Armour OFFICIAL
- 10. © Crown copyright 2014 Dstl 01 October 2014 Key problem space (3) Bases • Infrastructure • Protection • Power / Waste OFFICIAL
- 11. © Crown copyright 2014 Dstl 01 October 2014 Key problem space (4) Logistics • ‘The oil of war’ • More responsive, predictive, logistics • As far forward as possible OFFICIAL
- 12. Key themes • Materials • Power • Sensors © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 13. Application of Synthetic Biology Tools to address Defence Challenges © Crown copyright 2014 Dstl 01 October 2014 How can this emerging technology address defence challenges? OFFICIAL
- 14. OFFICIAL Synthetic Biology • Integrated approach for UK – From basic science to industrial application – Includes defence © Crown Copyright Dstl 2014
- 15. OFFICIAL Synthetic biology • Relevance to MOD – Integration into research programme to provide solutions – Understand potential impact on Threat and mitigate – Legislation © Crown Copyright Dstl 2014 www.syntheticgenomics.com
- 16. OFFICIAL Synthetic biology aims to design and engineer novel biologically-based parts, devices and systems, as well as redesign existing natural biological systems for useful purposes. It incorporates the principles of engineering eg modularity, abstraction and orthogonality into classical biotechnology. © Crown copyright 2014 Dstl 01 October 2014
- 17. 1 October, 2014 OFFICIAL © Crown copyright 2014 Dstl BUT….if it isn’t clear to the assessors how the application exploits synthetic biology, it will be out! There are other definitions….
- 18. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Synthetic Biology and Defence Technology Readiness Level LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE
- 19. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Synthetic Biology and Defence Technology Readiness Level LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE BUY
- 20. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Synthetic Biology and Defence Technology Readiness Level LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE WATCH
- 21. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Synthetic Biology and Defence Technology Readiness Level LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE INVEST TO ADAPT OR APPLY DEFENCE APPLICATIONS
- 22. OFFICIAL Priorities in the competition © Crown copyright 2014 Dstl 01 October 2014 Challenge 1: Exploiting synthetic biology for protection Challenge 2: Novel sensor technologies Challenge 3: Potential revolutions Synthetic Biology Novelty, Quality, Impact, Risk, Value Incremental, vague, outside scope, no defence application identified
- 23. OFFICIAL Challenge 1: Protection © Crown copyright 2014 Dstl 01 October 2014 Don’t be there Don’t be seen Don’t be targeted Don’t be hit Don’t be penetrated Don’t be killed Built in redundancy
- 24. OFFICIAL Challenge 1: Protection • People, bases, platforms • Against a range of forms of attack – physical attack ie projectiles or blast – chemical and biological agents – energy eg lasers etc • Avoiding attack in the first place – eg camouflage • Saving lives, protecting equipment – traumatic injury, sea survival, crash and post-crash survival, aircraft ejection, hostile environments • Novel materials of particular interest © Crown copyright 2014 Dstl 01 October 2014
- 25. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Challenge 2: Sensors Sensors LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE CB(D)E* Sonar, radar etc Gravity, material integrity, etc *Chemical, Biological (inc Diagnostics), Explosives
- 26. OFFICIAL Sensors….higher TRL • Chemical and Biological threat agents • Explosives Seeking technologies applicable to a wide range of challenges Prior demonstration of preliminary feasibility – Focus on issues such as improving confidence in outputs and reducing the logistic burden – Sample acquisition, preparation and pre-processing must be included © Crown copyright 2014 Dstl 01 October 2014
- 27. OFFICIAL Sensors….lower TRL • Protective coating integrity • Environmental sensors • Magnetic fields, acoustic, visible light, infra red, and ultra violet wavelengths (and beyond?) in ground, air or water • Contaminants or signatures in air, water or soil • Remote gravity fluctuations induced by large equipment • On the spot DNA analysis for identification © Crown copyright 2014 Dstl 01 October 2014
- 28. OFFICIAL © Crown copyright 2014 Dstl 01 October 2014 Sensors in Defence LOW HIGH BASIC RESEARCH COMMERCIALLY AVAILABLE Sensors CB(D)E* *Chemical, Biological (inc Diagnostics), Explosives
- 29. OFFICIAL Challenge 3: Revolutions • Not covered above in 1 and 2 • Synthetic biology applications with defence relevance • Novel materials of particular interest • Power – “materials that can be used to produce or store power” – no synthetic approaches to fuels • High TRL and significant commercial investment already © Crown copyright 2014 Dstl 01 October 2014
- 30. OFFICIAL Materials…. • New materials are potentially transformational – Synthetic biology routes to existing compounds are not needed • Must involve synthetic biology at some stage in their production • Likely require multidisciplinary teams and approaches • Production of sufficient material to demonstrate desired property • Military application must be identified • Challenges 1 and 3 – Application will decide which is the most appropriate © Crown copyright 2014 Dstl 01 October 2014
- 31. © Crown copyright 01 October 2014 Programme vision for materials “……..exploiting global investment in state of the art materials and structures science for enhanced defence and security capability.” Future proofing that from which defence equipment is made! OFFICIAL
- 32. Challenges • Challenge 1: Protection • Challenge 2: Sensors • Challenge 3: not covered above • Pick the most appropriate one for the application selected • No pre-determined allocation of funds between challenges OFFICIAL © Crown copyright 2014 Dstl 01 October 2014
- 33. What we don’t want • Routes to existing materials and compounds – including antibiotics • Existing solutions or technology, which have already been tested and found to have limited utility • Proposals that comprise a paper study, review or similar OFFICIAL © Crown copyright 2014 Dstl 01 October 2014
- 34. What we don’t want • Solutions requiring the release of genetically modified organisms (GMOs) into the environment • Proposals in areas where there is already a significant research effort – unless a clearly defined new application relevant to defence and security • Proposals without a synthetic biology component in the approach OFFICIAL © Crown copyright 2014 Dstl 01 October 2014
- 35. Bidding… improving your chances • Identify the defence application clearly – What will be the benefit? • Identify the synthetic biology component clearly • How is this highly innovative? • What advantages does this provide over currently available solutions? • Have you assembled a team that can do this? © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 36. Bidding… improving your chances • Read the guidance • Submit early • The deadline really is the deadline © Crown copyright 2014 Dstl 01 October 2014 OFFICIAL
- 37. Synthetic Biology • Deadline: Thursday 6 November 2014 at 5pm • Technical Partners for successful bids • Exploitation – Phase 2 • Potentially up to £3 million for Phase 2 funding – Main MOD research programme – Commercial partners OFFICIAL © Crown copyright 2014 Dstl 01 October 2014