This document summarizes a webinar presented by the Centre for Defence Enterprise (CDE) on funding opportunities for research on innate host response targets for therapy against biothreat agents. The CDE is launching a themed competition seeking short proof-of-concept proposals in three challenge areas: 1) Identification of new cellular or host pathway targets, 2) Identification of new candidate therapies, and 3) Identification of new platform technologies for assessing therapeutic benefit. Successful proposals will receive up to £80,000 in funding and may qualify for additional follow-on funding to further develop technologies of interest to the UK Ministry of Defence. The competition aims to fund highly innovative early-stage research with potential military and civilian applications.