The document discusses the structure and function of cell membranes. It describes how the fluid mosaic model proposes that cell membranes are made of a bilayer of phospholipids with embedded proteins that move freely within the bilayer. The major components are phospholipids, cholesterol, proteins, and carbohydrates. Transport across the membrane occurs through diffusion, facilitated diffusion, and active transport using carrier proteins. Tight junctions between cells help regulate transport and maintain cell homeostasis.
endocytosis and exocytosis is a procss of cell eating and drinnking. it is a mazor tool for self defence to an individual cell. there are some molecular mechanism for this process described in given notes.
The Cell signalling is part of any communication process that governs basic activities of cells and coordinates all cell actions.
The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, immunity, tissue homeostasis.
The cell membrane receptors and internal receptors have been discussed along with current trends in cell signalling.
1. Visualization of cell signalling
2. Stem cells and cell signalling
This Presentation Deals With What Is A Cell Signalling, The Components, Its Stages, Main Events Involved, Autocrine Signalling, Paracrine Signalling, Endocrine Signalling And The References Respectively.
Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins
This presentation gives an overview of Lipid Rafts, how it was discovered, its importance and the future research in this area,Feel free to comment and ask any questions
Extra cellular matrix is recently being explored in connection with cancer , metastases and autoimmune disorders. It is prepared for the benefit of both UG and PG medical and dental students.
endocytosis and exocytosis is a procss of cell eating and drinnking. it is a mazor tool for self defence to an individual cell. there are some molecular mechanism for this process described in given notes.
The Cell signalling is part of any communication process that governs basic activities of cells and coordinates all cell actions.
The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, immunity, tissue homeostasis.
The cell membrane receptors and internal receptors have been discussed along with current trends in cell signalling.
1. Visualization of cell signalling
2. Stem cells and cell signalling
This Presentation Deals With What Is A Cell Signalling, The Components, Its Stages, Main Events Involved, Autocrine Signalling, Paracrine Signalling, Endocrine Signalling And The References Respectively.
Facilitated diffusion (also known as facilitated transport or passive-mediated transport) is the process of spontaneous passive transport (as opposed to active transport) of molecules or ions across a biological membrane via specific transmembrane integral proteins
This presentation gives an overview of Lipid Rafts, how it was discovered, its importance and the future research in this area,Feel free to comment and ask any questions
Extra cellular matrix is recently being explored in connection with cancer , metastases and autoimmune disorders. It is prepared for the benefit of both UG and PG medical and dental students.
• The membrane enclosing a cell is called cell membrane or plasma membrane (animal cells) and plasma lemma (plant cells).
• It contains proteins and lipids in the ratio of 80 : 20 in bacteria on one extreme and on the other extreme 20 : 80 in some nerve cells.
• The over all composition of most of the cell membranes is 40-50% protein and 50-60% lipids; both the components vary in their composition.
Structure and functions of cell, transport across cell membrane, cell
division, cell junctions. General principles of cell communication,
the smallest unit that can live on its own and that makes up all living organisms and the tissues of the body
The basic tenets of the cell theory are as follows:
All living things are made up of one or more cells.
The cell is the structural and functional unit of all living things.
Cells come from pre-existing cells through the process of division.
All cells are the same in regard to chemical composition.
Cells also communicate with each other. Whether in plants, humans, or animals, they connect to create a solid, well formed organism. In humans, cells build tissues, tissues form organs, and organs work together to keep the body alive.
Experts estimate that there are around 200Trusted Source cell types in the human body.
TRANSPORT PROCESS ACROSS CELL MEMBRANE.pptxPoojaDahale3
For a drug to get absorbed after oral administration, it must first pass through this biological barrier. Such a movement of drug across the membrane is called as drug transport.
It is the boundary that separates the cell from its surroundings.
It regulate the exchange of substances between inside and outside of the cell. It is semi-permeable.
It is made up of lipids, proteins, and carbohydrates.
Cell structure slideshare.pptx Unlocking the Secrets of Cells: Structure, Fun...ananyagirishbabu1
Dive into the intricate world of cells with our detailed Slideshare presentation. This educational resource is designed to provide a thorough understanding of cells, the fundamental building blocks of all living organisms. Ideal for students, educators, and biology enthusiasts, this presentation covers:
Introduction to Cell Theory: Discover the historical development of cell theory and its significance in modern biology.
Types of Cells: Compare and contrast prokaryotic and eukaryotic cells, highlighting their unique features and functions.
Cell Organelles and Their Functions: Explore the various organelles within a cell, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and more, each described with their specific roles.
Cell Membrane Structure and Function: Learn about the composition and function of the cell membrane, including its role in regulating the movement of substances in and out of the cell.
Cell Division and Reproduction: Understand the processes of mitosis and meiosis, key to cellular replication and genetic diversity.
Specialized Cells: Investigate the diversity of cell types, including muscle cells, nerve cells, and blood cells, and their specialized functions in multicellular organisms.
Interactive Diagrams and Visual Aids: Engage with detailed diagrams and illustrations that clarify complex concepts and enhance learning.Introduction to Cell Theory: Discover the historical development of cell theory and its significance in modern biology.
Types of Cells: Compare and contrast prokaryotic and eukaryotic cells, highlighting their unique features and functions.
Cell Organelles and Their Functions: Explore the various organelles within a cell, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and more, each described with their specific roles.
Cell Membrane Structure and Function: Learn about the composition and function of the cell membrane, including its role in regulating the movement of substances in and out of the cell.
Cell Division and Reproduction: Understand the processes of mitosis and meiosis, key to cellular replication and genetic diversity.
Specialized Cells: Investigate the diversity of cell types, including muscle cells, nerve cells, and blood cells, and their specialized functions in multicellular organisms.
Interactive Diagrams and Visual Aids: Engage with detailed diagrams and illustrations that clarify complex concepts and enhance learning.
This Slideshare presentation is a valuable educational tool, offering clear explanations and engaging visuals to help you grasp the essential concepts of cellular biology. Whether preparing for exams, teaching a class, or simply exploring the microscopic foundations of life, this resource provides a comprehensive overview of the fascinating world of cells. Explore the fascinating world of cells with our comprehensive SlideShare presentation. This educational resource delves into the fundamental unit of life,
Similar to 3. Structure and function of cell membrane (Biochemistry) (20)
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
3. • Plasma membrane was discovered by Schwann
(1838)
• Named as cell membrane by Nageli and Cramer
(1855)
• Membrane was given the name of Plasmalemma
by Plowe (1931)
• Chemically a biomolecule consists of lipid (20-
40%), proteins (59-75%) and carbohydrates
(1-5%)
• Important lipids of the membrane is
Phospholipids (some 100 types), sterols (e.g.,
cholesterol), glycolipids, sphingolipids (e.g.,
sphingomyelin, cerebrosides).
4. • Carbohydrates present in the membrane are
branched or unbranched oligosaccharides,
e.g., hexose, fructose, hexosamine, sialic
acid, etc.
• Protein can be fibrous or globular, structural,
carrier, receptors or enzymatic.
• Several types of models explained structure
of plasma membrane:
• Lamellar models/ sandwich model (Danielli and
Davson, 1935)
• Robertson model (David Robertson, 1959)
• Fluid-Mosaic model (Singer and Nicolson, 1972)
5. Fluid-Mosaic model
• The currently accepted model for the structure of
the plasma membrane, called the fluid mosaic
model, was first proposed by Singer and Nicolson
in 1972.
• According to the fluid mosaic model, the plasma
membrane is a mosaic of components-primarily,
phospholipids, cholesterol, and proteins-that move
freely and fluidly in the plane of the membrane.
• The principal components of the plasma
membrane are lipids (phospholipids and
cholesterol), proteins, and carbohydrate groups
that are attached to some of the lipids and
proteins.
6.
7. • A phospholipid is a lipid made of glycerol, two
fatty acid tails, and a phosphate-linked head group.
Biological membranes usually involve two layers of
phospholipids with their tails pointing inward, an
arrangement called a phospholipid bilayer.
• Cholesterol, another lipid composed of four fused
carbon rings, is found alongside phospholipids in
the core of the membrane.
• Carbohydrate groups are present only on the outer
surface of the plasma membrane and are attached to
proteins, forming glycoproteins , or lipids, forming
glycolipids.
8.
9. • Phospholipids, arranged in a bilayer, make up the
basic fabric of the plasma membrane. They are
well-suited for this role because they are
amphipathic.
• The hydrophilic, or "water-loving," portion of a
phospholipid is its head, which contains a
negatively charged phosphate group as well as an
additional small group which may also or be
charged or polar.
• The hydrophilic heads of phospholipids in a
membrane bilayer face outward, contacting the
aqueous (watery) fluid both inside and outside the
cell. Since water is a polar molecule, it readily
forms electrostatic (charge-based) interactions with
the phospholipid heads.
10. • The hydrophobic, or "water-fearing," part of a
phospholipid consists of its long, nonpolar fatty acid
tails. The fatty acid tails can easily interact with
other nonpolar molecules, but they interact poorly
with water.
• The phospholipid bilayer formed by these
interactions makes a good barrier between the
interior and exterior of the cell, because water and
other polar or charged substances cannot easily
cross the hydrophobic core of the membrane.
11.
12. • Proteins are the second major component of plasma
membranes. There are two main categories of
membrane proteins: integral and peripheral.
• The portions of an integral membrane protein found
inside the membrane are hydrophobic, while those
that are exposed to the cytoplasm or extracellular
fluid tend to be hydrophilic.
• Some integral membrane proteins form a channel
that allows ions or other small molecules to pass.
• Peripheral membrane proteins are found on the
outside and inside surfaces of membranes, attached
either to integral proteins or to phospholipids.
13.
14. • Carbohydrates are the third major component of
plasma membranes. In general, they are found on
the outside surface of cells and are bound either to
proteins (forming glycoproteins) or to lipids
(forming glycolipids).
• These carbohydrate chains may consist of 2-60
monosaccharide units and can be either straight or
branched.
• Along with membrane proteins, these carbohydrates
form distinctive cellular markers, sort of like
molecular ID badges, that allow cells to recognize
each other.
15. • Carbohydrates are the third major component of
plasma membranes. In general, they are found on
the outside surface of cells and are bound either to
proteins (forming glycoproteins) or to lipids
(forming glycolipids).
• These carbohydrate chains may consist of 2-60
monosaccharide units and can be either straight or
branched.
• Along with membrane proteins, these carbohydrates
form distinctive cellular markers, sort of like
molecular ID badges, that allow cells to recognize
each other.
17. • Tight junctions, also known as occluding junctions
or zonulae occludentes (singular, zonula
occludens) are multiprotein junctional complexes
whose general function is to prevent leakage of
transported solutes and water and seals the
paracellular pathway.
• Tight junctions may also serve as leaky pathways
by forming selective channels for small cations,
anions, or water.
• Tight junctions (TJ) are specialized membrane
structures found in cell-cell contact areas where the
membranes of the neighboring cells come into a
close proximity.
• Tight junctions are present only in vertebrates.
18. • Tight junctions are composed of branching network of
sealing strands, each started acting independently from
the others.
• Therefore, the efficiency of the junction in preventing
ion passage increases exponentially with the number
of strands.
• There are at least 40 different proteins composing the
tight junctions.
• These proteins consist of both transmembrane and
cytoplasmic proteins.
• The three major transmembrane proteins are occludin,
claudins, and junction adhesion molecule (JAM)
proteins.
Structure of tight junction
19. • They hold cells together.
• Barrier function, which can be further subdivided into
protective barriers and functional barriers serving
purposes such as material transport and maintenance
of osmotic balance:
• Aims to preserve the transcellular transport.
• Tight junctions prevent the passage of molecules
and ions through the space between plasma
membranes of adjacent cells, so materials must
actually enter the cells (by diffusion or active
transport) in order to pass through the tissue.
Function of tight junction
21. • The cell membrane is one the great multitasker of
biology .
• It provides structure for the cell, protects cytosolic
contents from the environment, and allow cells to
act as specialized unit.
• This phospholipid bilayer can determine that what
molecule can move into or out of the cell, and so is
in large part responsible for maintaining the delicate
homeostasis of each cell.
• Transport: Transport is any process in which
movement of matter and/or energy occurs from one
part of a system to another.
22.
23. Diffusion
• Diffusion is the net movement of material from an
area of high concentration of that substance to an
area with lower concentration of that substance.
• Simple Diffusion means that kinetic movement of
molecules or ions occurs through a membrane
opening or through intermolecular spaces without
any interaction with carrier proteins in the
membrane.
• Simple diffusion of lipid – soluble substances can
take place through the lipid bilayer , its rate
dependent on how highly lipid soluble it is (E.g.
oxygen , carbon dioxide , nitrogen , alcohol ).
24. • Water & lipid -insoluble substances simply diffuse
through protein channels, the number and size of
openings available determining its rate.
• The protein channels involved in simple diffusion
are distinguished by 2 important characteristics:
• They are often selectively permeable to certain
substances.
• Many of the channels can be opened or closed by
gates.
• Facilitated diffusion is also called carrier-mediated
diffusion because a substance transported in this
manner diffuses through the membrane using a
specific carrier protein to help.
25.
26. •Fick’s Law of Diffusion:
The net diffusion rate of a gas across a
fluid membrane is proportional to the
difference in concentration, to the surface
area of the membrane, to the permeability
of the membrane to the substance and
inversely proportional to the thickness of
the membrane and molecular weight of the
molecule.
27.
28.
29. • The osmotic pressure is defined to be the pressure
required to maintain equilibrium, with no net
movement of solvent .
• Osmotic pressure depends on the molar
concentration of the solute but not on its identity . It
is the exact amount of pressure required to stop
osmosis.
• The tonicity of a solution refers to the effect on cell
volume of the concentration of non – penetrating
solutes in the solution surrounding the cell.