พยาธิกำเนิดระบบไหลเวียน

1. พยาธิส รีร วิท ยาโรคระบบไหลเวีย น
โดย
รศ.พ.ต.อ.หญิง ดร.ศิร ิม า
เขมะเพชร

3. กษณะโครงสร้า งของหัว ใจ
- ตำา แหน่ง 2nd intercostal space ดึง 6th
intercostal space pericardium
- fibrous pericardium
- serous pericardium
มี pericardial
fluid/perdicardial
- parietal
eavity
- visceral/epicardium

4. Wall
*epicardium
*myocardium
*endocardium
hamber
*atrium (Lt., Rt.)
*ventricle (Lt.,Rt.)
Valve
*AV-valve
(tricuspid,
bicuspid)
*semilunar

5. ษณะเซลล์ก ล้า มเนือ หัว ใจ
้

6. Conduction system
SA-node
Atrial cell (Rt., Lt.)
AV-node
Bundle branches (Rt., Lt)
Purkinje fibers
apillary muscle
Ventricular cell
AV-valve ปิด
contraction

8. รูป Cardiac cycle

9. Hemodynamic ในหัว ใจ

15. Cardiovascular Disease
 Cerebrovascular disease and
heart disease are the
second, third of the leading
causes of death.
 Years of life lost are much
more than other disease.

16. Risk Factors
Hypertension
Hypercholestrolemia
diabetes
obesity
high dietary salt
alcohol and cigarette
consumption







17. ophysiology of cardiovascular

21. diovascular dysfunction
ardiomyopathy
Heart failure
*Lt.side
*Rt.side
Dysrhythmia
ascular diseases

23. ns & symptoms of heart fail

24. ht-side heart failure
*ตับ โต (hepatomegaly)
*ปวดแน่น ช่อ งท้อ ง (abdominal
comfort)
*เบือ อาหาร (anorexia)
่
*ขาบวม (swelling)
*ท้อ งบวม (ascites)
de heart failure
ลือ ดคัง ในปอด (pulmonary edema)
่
หนือ ย (tiredness)
่
หอบ (shortness of breath)
ไอเป็น เลือ ด (blood-tinged mucous)
นอนราบไม่ไ ด้

28. Arrhythmia
หัว ใจมีก ารเต้น
ผิด จัง หวะ;
rial fibrilation
*
omplete heart
ock

31. Vascular dysfunction

32. Vascular structure

34. Vascular function disorder
arteries
vein
eases
therosclerosis
ypertension
rthostatic (postural) hypotension
neurysm
hrombus formation
mbolism
eripheral arterial disease
isease of vein
*CAD, myocardial ischem

35. therosclerosis
onic disease of arterial
em
ammatory disease
aracterized by abnormal
kening and hardening of the
el walls
accumulation of lipid-laden
phages within the arterial walls
“plaque”

45. Ischemic syndrome
Throughout the body
*coronary arteries
*cerebrovascular dise
etc

47. jor risk factors
Endothelial injury
smoking
hypertension
diabetes
Chronic inflammatio
ncreased LDL
decreased HDL
plaque
hyperhomocystinemia
atherosclerosis
CAD
HT
Myocardial infarction
Stroke (brain

48. ocardial infarction

49. Defined as
Hypertension
a sustained elevation
systemic arterial blood pressure

52. Coronary artery disease

54. angina
Is the chest pain
or discomfort that
occur when your
heart muscle does
not get enough
blood

57. Avoid sedentary lifestyle

58. Prevention strategies

59. Five Dimensions
Control Plan
Establishing a
comprehensive prevention
and control system
Strengthening educational
activities
Implementing screening
and care management
Providing affordable

60. Establishing a comprehensive
prevention
and control system

Integrating government, medical care facilities, and
community resources to collaborate in prevention
program.

Developing national guidelines on hypertension,
dyslipidemia and diabetes .

The Tobacco Hazards Prevention Act (1997) regulates
the sales promotion of tobacco products, restriction
on smoking area, smoke cessation and anti-smoking
education.

Conducting regular experts committee to supervise